Rebecca A. Weingarten

MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Proteins / physiology; Campylobacter jejuni / enzymology; Campylobacter jejuni / genetics; Campylobacter jejuni / growth & development; Campylobacter jejuni / metabolism; Chickens; Citric Acid Cycle / genetics; Citric Acid Cycle / physiology; Fumarates / metabolism; Models, Genetic; Oxygen / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Succinate Dehydrogenase / genetics; Succinate Dehydrogenase / metabolism; Succinate Dehydrogenase / physiology; Succinic Acid / metabolism

TL;DR: Campylobacter jejuni encodes all the enzymes necessary for a complete oxidative tricarboxylic acid (TCA) cycle and the in vivo importance of succinate oxidation was confirmed, as the frdA::cat(+) strain colonized chickens at significantly lower levels than the wild type, while the sdhA:: cat(+) strain colonize chickens at wild-type levels. (via Semantic Scholar)

MeSH headings : Animals; Campylobacter jejuni / enzymology; Campylobacter jejuni / growth & development; Cecum / microbiology; Chickens / microbiology; Colony Count, Microbial; DNA Primers / genetics; Gene Components; Mass Spectrometry; Mutagenesis; Nitrates / metabolism; Oxidoreductases / genetics; Oxidoreductases / metabolism; Oxygen / metabolism; Species Specificity

TL;DR: While there appears to be a role for anaerobic respiration in host colonization, oxygen is the most important respiratory acceptor for C. jejuni in the chicken cecum. (via Semantic Scholar)