Works (8)

2016 journal article

Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection

Proceedings of the National Academy of Sciences of the United States of America, 113(41), E6080–6088.

By: J. Maciag, S. Mackenzie, M. Tucker, J. Schipper, P. Swartz & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Modifying caspase-3 activity by altering allosteric networks

Biochemistry, 53(48), 7582–7595.

By: C. Cade, P. Swartz, S. MacKenzie & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Redesigning the procaspase-8 dimer interface for improved dimerization

Protein Science, 23(4), 442–453.

By: C. Ma, S. MacKenzie & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Lengthening the intersubunit linker of procaspase 3 leads to constitutive activation

Biochemistry, 52(36), 6219–6231.

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Slow folding and assembly of a procaspase-3 interface variant

Biochemistry, 52(20), 3415–3427.

By: S. MacKenzie & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

A bifunctional allosteric site in the dimer interface of procaspase-3

Biophysical Chemistry, 159(1), 100–109.

By: J. Schipper, S. MacKenzie, A. Sharma & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2010 review

The potential for caspases in drug discovery

[Review of ]. Current Opinion in Drug Discovery & Development, 13(5), 568–576.

By: S. MacKenzie, J. Schipper & A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2008 review

Targeting cell death in tumors by activating Caspases

[Review of ]. Current Cancer Drug Targets, 8(2), 98–109.

By: S. MacKenzie & A. Clark

Source: NC State University Libraries
Added: August 6, 2018