Works (116)

2019 journal article

A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies

DIABETES, 68(8), 1649–1662.

By: Y. Tang, P. Lenzini, R. Pop-Busui, P. Ray, H. Campbell, B. Perkins, B. Callaghan, M. Wagner ...

Source: Web Of Science
Added: August 12, 2019

2019 article

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts

SCIENTIFIC DATA.

By: L. St John-Williams, S. Mahmoudiandehkordi, M. Arnold, T. Massaro, C. Blach, G. Kastenmueller, G. Louie, A. Kueider-Paisley ...

Source: Web Of Science
Added: November 11, 2019

2019 journal article

Cheminformatics approach to exploring and modeling trait-associated metabolite profiles

JOURNAL OF CHEMINFORMATICS, 11.

By: J. Ash, M. Kuenemann, D. Rotroff, A. Motsinger-Reif & D. Fourches

Source: Web Of Science
Added: July 15, 2019

2019 journal article

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

NATURE COMMUNICATIONS, 10.

By: M. Menden, D. Wang, M. Mason, B. Szalai, K. Bulusu, Y. Guan, T. Yu, J. Kang ...

Source: Web Of Science
Added: July 1, 2019

2019 journal article

Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex

CHROMOSOME RESEARCH, 27(3), 179–202.

By: K. Kennedy, R. Thomas, J. Durrant, T. Jiang, A. Motsinger-Reif & M. Breen

Source: Web Of Science
Added: September 30, 2019

2019 journal article

Identifying individual risk rare variants using protein structure guided local tests (POINT)

PLOS COMPUTATIONAL BIOLOGY, 15(2).

By: R. West, W. Lu, D. Rotroff, M. Kuenemann, S. Chang, M. Wu, M. Wagner, J. Buse ...

Source: Web Of Science
Added: March 25, 2019

2019 article

Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy

JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: P. Fox, B. Keene, K. Lamb, K. Schober, V. Chetboul, V. Fuentes, J. Payne, G. Wess ...

Source: Web Of Science
Added: October 28, 2019

2019 journal article

Untargeted Metabolomic Profiling Identifies Disease-Specific Pathways in Food Allergy and Asthma

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 143(2), AB255–255.

By: E. Crestani, J. Leirer, A. Motsinger-Reif, W. Phipatanakul, R. Kaddurah-Daouk & T. Chatila

Source: NC State University Libraries
Added: February 25, 2019

2018 journal article

Gene expression and linkage analysis implicate as a mediator of rituximab resistance

Pharmacogenomics Journal, 18(3), 467–473.

By: J. Jack, G. Small, C. Brown, T. Havener, H. McLeod, A. Motsinger-Reif, K. Richards

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Gene set analysis methods: A systematic comparison

Biodata Mining, 11.

By: R. Mathur, D. Rotroff, J. Ma, A. Shojaie & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

DIABETES CARE, 41(11), 2404–2413.

By: M. Morieri, H. Gao, M. Pigeyre, H. Shah, J. Sjaarda, C. Mendonca, T. Hastings, P. Buranasupkajorn ...

Source: NC State University Libraries
Added: November 5, 2018

2018 journal article

Genetic variants in CPA6 and PRPF31 are associated with variation in response to metformin in individuals with type 2 diabetes

Diabetes, 67(7), 1428–1440.

By: D. Rotroff, S. Yee, K. Zhou, S. Marvel, H. Shah, J. Jack, T. Havener, M. Hedderson ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study

Journal of Veterinary Internal Medicine, 32(3), 930–943.

By: P. Fox, B. Keene, K. Lamb, K. Schober, V. Chetboul, V. Fuentes, G. Wess, J. Payne ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Modulation of GLP-1 levels by a genetic variant that regulates the cardiovascular effects of intensive glycemic control in ACCORD

Diabetes Care, 41(2), 348–355.

By: H. Shah, M. Morieri, S. Marcovina, R. Sigal, H. Gerstein, M. Wagner, A. Motsinger-Reif, J. Buse ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Pharmacogenetic analysis of the model-based pharmacokinetics of five anti-HIV drugs: How does this influence the effect of aging?

Clinical and Translational Science, 11(2), 226–236.

By: J. Chen, F. Akhtari, M. Wagner, O. Suzuki, T. Wiltshire, A. Motsinger-Reif, J. Dumond

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 7(8), 525–533.

By: R. Kaddurah-Daouk, T. Hankemeier, E. Scholl, R. Baillie, A. Harms, C. Stage, K. Dalhoff, G. Jurgens ...

Source: NC State University Libraries
Added: October 16, 2018

2018 journal article

Sphingolipid metabolic pathway impacts thiazide diuretics blood pressure response: Insights from genomics, metabolomics, and lipidomics

Journal of the American Heart Association, 7(1).

By: M. Shahin, Y. Gong, R. Frye, D. Rotroff, A. Beitelshees, R. Baillie, A. Chapman, J. Gums ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

The influence of Neanderthal alleles on cytotoxic response

PEERJ, 6.

By: F. Akhtari, T. Havener, M. Fukudo, J. Jack, H. McLeod, T. Wiltshire, A. Motsinger-Reif

Source: NC State University Libraries
Added: November 5, 2018

2017 review

An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines

Frontiers in Pharmacology.

By: K. Roell, D. Reif & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Assessment of potential miRNA biomarkers of VERO-cell tumorigenicity in a new line (AGMK1-9T7) of African green monkey kidney cells

Vaccine, 35(41), 5503–5509.

By: B. Teferedegne, D. Rotroff, J. Macauley, G. Foseh, G. Lewis, A. Motsinger-Rief, A. Lewis

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Association of breed and histopathological grade in canine mast cell tumours

Veterinary and Comparative Oncology, 15(3), 829–839.

By: H. Mochizuki, A. Motsinger-Reif, C. Bettini, S. Moroff & M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial

PeerJ, 5.

By: S. Marvel, D. Rotroff, M. Wagner, J. Buse, T. Havener, H. McLeod, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2017 article

Common genetic variants in neurobeachin (nbea) are associated with metformin drug response in individuals with type 2 diabetes in the accord clinical trial

Clinical Pharmacology & Therapeutics.

By: D. Rotroff, S. Marvel, J. Jack, T. Havener, A. Doria, H. Shah, J. Mychaleckyi, H. McLeod ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Data descriptor: Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

Scientific Data, 4.

By: L. St John-Williams, C. Blach, J. Toledo, D. Rotroff, S. Kim, K. Klavins, R. Baillie, X. Han ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Metabolic network failures in Alzheimer's disease: A biochemical road map

Alzheimers & Dementia, 13(9), 965–984.

By: J. Toledo, M. Arnold, G. Kastenmuller, R. Chang, R. Baillie, X. Han, M. Thambisetty, J. Tenenbaum ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

The The effect of heart disease on anesthetic complications during routine dental procedures in dogs

Journal of the American Animal Hospital Association, 53(4), 206–213.

By: J. Carter, A. Motsinger-Reif, W. Krug & B. Keene

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: Effects of estradiol and progesterone addback

Translational Psychiatry, 7.

By: T. Nguyen, J. Reuter, N. Gaikwad, D. Rotroff, H. Kucera, A. Motsinger-Reif, C. Smith, L. Nieman ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Thromboelastographic monitoring of the effect of unfractionated heparin in healthy dogs

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001), 27(1), 71–81.

By: C. McLaughlin, S. Marks, D. Dorman, A. Motsinger-Reif & R. Hanel

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

A A comparison of DMET Plus microarray and genome-wide technologies by assessing population substructure

Pharmacogenetics and Genomics, 26(4), 147–153.

By: J. Jackson, K. Long, Y. He, A. Motsinger-Reif, H. McLeod & J. Jack

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

A European spectrum of pharmacogenomic biomarkers: Implications for clinical pharmacogenomics

PLoS One, 11(9).

By: C. Mizzi, E. Dalabira, J. Kumuthini, N. Dzimiri, I. Balogh, N. Basak, R. Bohm, J. Borg ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

A genetic response score for hydrochlorothiazide use insights from genomics and metabolomics integration

Hypertension, 68(3), 621-.

By: M. Shahin, Y. Gong, C. McDonough, D. Rotroff, A. Beitelshees, T. Garrett, J. Gums, A. Motsinger-Reif ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies

Pharmacogenetics and Genomics, 26(7), 324–333.

By: M. Irvin, D. Rotroff, S. Aslibekyan, D. Zhi, B. Hidalgo, A. Motsinger-Reif, S. Marvel, V. Srinivasasainagendra ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Alpha-hydroxybutyric acid is a selective metabolite biomarker of impaired glucose tolerance

Diabetes Care, 39(6), 988–995.

By: J. Cobb, A. Eckhart, A. Motsinger-Reif, B. Carr, L. Groop & E. Ferrannini

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Carboplatin/taxane-induced gastrointestinal toxicity: a pharmacogenomics study on the SCOTROC1 trial

Pharmacogenomics Journal, 16(3), 243–248.

By: Y. He, S. Winham, J. Hoskins, S. Glass, J. Paul, R. Brown, A. Motsinger-Reif, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Comprehensive genomic characterization of five canine lymphoid tumor cell lines

BMC Veterinary Research, 12.

By: S. Roode, D. Rotroff, K. Richards, P. Moore, A. Motsinger-Reif, Y. Okamura, T. Mizuno, H. Tsujimoto, S. Suter, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes

Metabolomics, 12(11).

By: C. Chialvo, R. Che, D. Reif, A. Motsinger-Reif & L. Reed

Source: NC State University Libraries
Added: August 6, 2018

2016 review

Embracing integrative multiomics approaches

International Journal of Genomics.

By: D. Rotroff & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Genetic predictors of cardiovascular mortality during intensive glycemic control in type 2 diabetes: Findings from the ACCORD clinical trial

Diabetes Care, 39(11), 1915–1924.

By: H. Shah, H. Gao, M. Morieri, J. Skupien, S. Marvel, G. Pare, G. Mannino, P. Buranasupkajorn ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Genome-wide association study in immunocompetent patients with delayed hypersensitivity to sulfonamide antimicrobials

PLoS One, 11(6).

By: J. Reinhart, A. Motsinger-Reif, A. Dickey, S. Yale & L. Trepanier

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Incorporating concomitant medications into genome-wide analyses for the study of complex disease and drug response

Frontiers in Genetics, 7.

By: H. Graham, D. Rotroff, S. Marvel, J. Buse, T. Havener, A. Wilson, M. Wagner, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero

BMC Genomics, 17.

By: D. Rotroff, B. Joubert, S. Marvel, S. Haberg, M. Wu, R. Nilsen, P. Ueland, W. Nystad, S. London, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: New mechanistic insights for rapid acting antidepressants

Translational Psychiatry, 6.

By: D. Rotroff, D. Corum, A. Motsinger-Reif, O. Fiehn, N. Bottrel, W. Drevets, J. Singh, G. Salvadore, R. Kaddurah-Daouk

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Pharmacometabolomic assessment of metformin in non-diabetic, African Americans

Frontiers in Pharmacology, 7.

By: D. Rotroff, N. Oki, X. Liang, S. Yee, S. Stocker, D. Corum, M. Meisner, O. Fiehn ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy

American Journal of Veterinary Research, 77(7), 693–699.

By: S. Friedenberg, L. Chdid, B. Keene, B. Sherry, A. Motsinger-Reif & K. Meurs

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

Nature Genetics, 48(9), 1055-.

By: K. Zhou, S. Yee, E. Seiser, N. Leeuwen, R. Tavendalel, A. Bennett, C. Groves, R. Coleman ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Accuracy of SNPs to predict risk of HLA alleles associated with drug-induced hypersensitivity events across racial groups

Pharmacogenomics, 16(8), 817–824.

By: Y. He, J. Hoskins, S. Clark, N. Campbell, K. Wagner, A. Motsinger-Reif, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

An investigation of gene-gene interactions in dose-response studies with Bayesian nonparametrics

Biodata Mining, 8.

By: A. Beam, A. Motsinger-Reif & J. Doyle

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Canine urothelial carcinoma: genomically aberrant and comparatively relevant

Chromosome Research, 23(2), 311–331.

By: S. Shapiro, S. Raghunath, C. Williams, A. Motsinger-Reif, J. Cullen, T. Liu, D. Albertson, M. Ruvolo ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization

Chromosome Research, 23(2), 171–186.

By: K. Poorman, L. Borst, S. Moroff, S. Roy, P. Labelle, A. Motsinger-Reif, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Evaluating the role of admixture in cancer therapy via in vitro drug response and multivariate genome-wide associations

Pharmacogenomics, 16(13), 1451–1463.

By: J. Jack, T. Havener, H. McLeod, A. Motsinger-Reif & M. Foster

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation

Chromosome Research, 23(4), 681–708.

By: S. Roode, D. Rotroff, A. Avery, S. Suter, D. Bienzle, J. Schiffman, A. Motsinger-Reif, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Initial evaluation of nighttime restlessness in a naturally occurring canine model of osteoarthritis pain

PeerJ, 3.

By: D. Knazovicky, A. Tomas, A. Motsinger-Reif & B. Lascelles

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Operative factors associated with short-term outcome in horses with large colon volvulus: 47 cases from 2006 to 2013

Equine Veterinary Journal, 47(3), 279–284.

By: L. Gonzalez, C. Fogle, W. Baker, F. Hughes, J. Law, A. Motsinger-Reif, A. Blikslager

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Population-based in vitro hazard and concentration-response assessment of chemicals: The 1000 genomes high-throughput screening study

Environmental Health Perspectives, 123(5), 458–466.

By: N. Abdo, M. Xia, C. Brown, O. Kosyk, R. Huang, S. Sakamuru, Y. Zhou, J. Jack ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Relative quantification and higher-order modeling of the plasma glycan cancer burden ratio in ovarian cancer case-control samples

Journal of Proteome Research, 14(10), 4394–4401.

By: E. Hecht, E. Scholl, S. Walker, A. Taylor, W. Cliby, A. Motsinger-Reif, D. Muddiman

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

A A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs?

British Journal of Haematology, 167(1), 110–120.

By: D. LeVine, A. Birkenheuer, M. Brooks, S. Nordone, D. Bellinger, S. Jones, T. Fischer, S. Oglesbee ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

An adaptive permutation approach for genome-wide association study: Evaluation and recommendations for use

Biodata Mining, 7.

By: R. Che, J. Jack, A. Motsinger-Reif & C. Brown

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Bayesian neural networks for detecting epistasis in genetic association studies

BMC Bioinformatics, 15.

By: A. Beam, A. Motsinger-Reif & J. Doyle

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24

PLoS Genetics, 10(2).

By: C. Agler, D. Nielsen, G. Urkasemsin, A. Singleton, N. Tonomura, S. Sigurdsson, R. Tang, K. Linder ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Evaluation of thromboelastography for prediction of clinical bleeding in thrombocytopenic dogs after total body irradiation and hematopoietic cell transplantation

American Journal of Veterinary Research, 75(5), 425–432.

By: M. Bucknoff, R. Hanel, S. Marks, A. Motsinger-Reif & S. Suter

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy

Breast Cancer Research and Treatment, 145(1), 245–254.

By: D. Hertz, S. Roy, J. Jack, A. Motsinger-Reif, A. Drobish, L. Clark, L. Carey, E. Dees, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines

Pharmacogenomics, 15(2), 137–146.

By: C. Brown, T. Havener, M. Medina, J. Jack, R. Krauss, H. McLeod, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

Chromosome Research, 22(3), 305–319.

By: R. Thomas, L. Borst, D. Rotroff, A. Motsinger-Reif, K. Lindblad-Toh, J. Modiano, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Lymphoblastoid cell lines models of drug response: Successes and lessons from this pharmacogenomic model

Current Molecular Medicine, 14(7), 833–840.

By: J. Jack, D. Rotroff & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

PGxClean: a quality control GUI for the Affymetrix DMET chip and other candidate gene studies with non-biallelic alleles

Biodata Mining, 7.

By: D. Rotroff, J. Jack, N. Campbell, S. Clark & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Positive association between a glutathione-S-transferase polymorphism and lymphoma in dogs

Veterinary and Comparative Oncology, 12(3), 227–236.

By: J. Ginn, J. Sacco, Y. Wong, A. Motsinger-Reif, R. Chun & L. Trepanier

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Prevalence of onychectomy in cats presented for veterinary care near Raleigh, NC and educational attitudes toward the procedure

Veterinary Anaesthesia and Analgesia, 41(1), 48–53.

By: L. Lockhart, A. Motsinger-Reif, W. Simpson & L. Posner

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Relationship between mechanical thresholds and limb use in dogs with coxofemoral joint OA-associated pain and the modulating effects of pain alleviation from total hip replacement on mechanical thresholds

Veterinary Surgery, 43(5), 542–548.

By: A. Tomas, D. Marcellin-Little, S. Roe, A. Motsinger-Reif & B. Lascelles

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Single-nucleotide polymorphism data support the general unrelatedness of the males in the agricultural health study

Cancer Epidemiology Biomarkers, 23(10), 2192–2195.

By: J. Jack, A. Motsinger-Reif, S. Koutros, M. Alavanja, L. Freeman & J. Hoppin

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

VH1-44 gene usage defines a subset of canine B-cell lymphomas associated with better patient survival

Veterinary Immunology and Immunopathology, 157(3-4), 125–130.

By: H. Chen, G. Small, A. Motsinger-Reif, S. Suter & K. Richards

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Alfaxalone anesthesia in bullfrogs (Lithobates catesbeiana) by injection or immersion

Journal of Zoo and Wildlife Medicine, 44(4), 965–971.

By: L. Posner, K. Bailey, E. Richardson, A. Motsinger-Reif & C. Harms

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Alterations in metabolic pathways and networks in Alzheimer's disease

Translational Psychiatry, 3.

By: R. Kaddurah-Daouk, H. Zhu, S. Sharma, M. Bogdanov, S. Rozen, W. Matson, N. Oki, A. Motsinger-Reif ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

CYP2C8*3 increases risk of neuropathy in breast cancer patients treated with paclitaxel

Annals of Oncology, 24(6), 1472–1478.

By: D. Hertz, S. Roy, A. Motsinger-Reif, A. Drobish, L. Clark, H. McLeod, L. Carey, E. Dees

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas

Placenta, 34(7), 599–605.

By: L. Guo, S. Tsai, N. Hardison, A. James, A. Motsinger-Reif, B. Thames, E. Stone, C. Deng, J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL

Cancer Research, 73(16), 5029–5039.

By: K. Richards, A. Motsinger-Reif, H. Chen, Y. Fedoriw, C. Fan, D. Nielsen, G. Small, R. Thomas ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Gene selection and cancer type classification of diffuse large-B-cell lymphoma using a bivariate mixture model for two-species data

Human Genomics, 7.

By: Y. Su, D. Nielsen, L. Zhu, K. Richards, S. Suter, M. Breen, A. Motsinger-Reif, J. Osborne

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Genome-wide association studies in pharmacogenomics: Successes and lessons

Pharmacogenetics and Genomics, 23(8), 383–394.

By: A. Motsinger-Reif, E. Jorgenson, M. Relling, D. Kroetz, R. Weinshilboum, N. Cox, D. Roden

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Interview A discussion on genome-wide associations in pharmacogenomics

Pharmacogenomics, 14(4), 361–363.

By: S. Jones & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine

Pharmacogenomics, 14(16), 1929–1931.

By: D. Rotroff, R. Thomas, M. Breen & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction

Biodata Mining, 6.

By: H. Dai, R. Charnigo, M. Becker, J. Leeder & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

A A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT

Pharmacogenetics and Genomics, 22(11), 796–802.

By: C. Brown, T. Havener, M. Medina, J. Auman, L. Mangravite, R. Krauss, H. McLeod, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

A predictive model for Efavirenz dosing

Pharmacogenomics, 13(2), 137–138.

By: C. Brown, N. Oki, G. Hariani & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Assessing the utility of whole genome amplified DNA as a template for DMET Plus array

Clinical Chemistry and Laboratory Medicine, 50(8), 1329–1334.

By: Y. He, A. Misher, W. Irvin, A. Motsinger-Reif, H. McLeod & J. Hoskins

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel

Breast Cancer Research and Treatment, 134(1), 401–410.

By: D. Hertz, A. Motsinger-Reif, A. Drobish, S. Winham, H. McLeod, L. Carey, E. Dees

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Comparison of venous sampling methods for thromboelastography in clinically normal dogs

American Journal of Veterinary Research, 73(12), 1864–1870.

By: J. Walker, R. Hanel, B. Hansen & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2012 conference paper

Effects of acepromazine maleate on platelet function assessed by use of adenosine diphosphate activated- and arachidonic acid-activated modified thromboelastography in healthy dogs

In American Journal of Veterinary Research (Vol. 73, pp. 595–601).

By: B. Conner, R. Hanel, B. Hansen, A. Motsinger-Reif, M. Asakawa & C. Swanson

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Evaluation of polymorphisms in the sulfonamide detoxification genes CYB5A and CYB5R3 in dogs with sulfonamide hypersensitivity

Journal of Veterinary Internal Medicine, 26(5), 1126–1133.

By: J. Funk-Keenan, J. Sacco, Y. Wong, S. Rasmussen, A. Motsinger-Reif & L. Trepanier

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Evaluation of polymorphisms in the sulfonamide detoxification genes NAT2, CYB5A, and CYB5R3 in patients with sulfonamide hypersensitivity

Pharmacogenetics and Genomics, 22(10), 733–740.

By: J. Sacco, M. Abouraya, A. Motsinger-Reif, S. Yale, C. McCarty & L. Trepanier

Source: NC State University Libraries
Added: August 6, 2018

2012 personal communication

Loss of power in two-stage residual-outcome regression analysis in genetic association studies

Genetic Epidemiology.

By: R. Che, A. Motsinger-Reif & C. Brown

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Multivariate methods and software for association mapping in dose-response genome-wide association studies

Biodata Mining, 5.

By: C. Brown, T. Havener, M. Medina, R. Krauss, H. McLeod & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Twice-daily application of HIV microbicides alters the vaginal microbiota

MBio, 3(6).

By: J. Ravel, P. Gajer, L. Fu, C. Mauck, S. Koenig, J. Sakamoto, A. Motsinger-Reif, G. Doncel, S. Zeichner

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

A A comparison of multifactor dimensionality reduction and L-1-penalized regression to identify gene-gene interactions in genetic association studies

Statistical Applications in Genetics and Molecular Biology, 10(1).

By: S. Winham, C. Wang & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: Signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart

Genes, Chromosomes and Cancer, 50(11), 859–874.

By: A. Angstadt, A. Motsinger-Reif, R. Thomas, W. Kisseberth, C. Couto, D. Duval, D. Nielsen, J. Modiano, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Genomic profiling in CEPH cell lines distinguishes between the Camptothecins and Indenoisoquinolines

Molecular Cancer Therapeutics, 10(10), 1839–1845.

By: V. Watson, N. Hardison, T. Harris, A. Motsinger-Reif & H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees

PLoS One, 6(5).

By: V. Watson, A. Motsinger-Reif, N. Hardison, E. Peters, T. Havener, L. Everitt, J. Auman, D. Comins, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Insights into the inhibition of platelet activation by omega-3 polyunsaturated fatty acids: Beyond aspirin and clopidogrel

Thrombosis Research, 128(4), 335–340.

By: M. Cohen, J. Rossi, J. Garbarino, R. Bowling, A. Motsinger-Reif, C. Schuler, A. Dupont, D. Gabriel

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior

BMC Cancer, 11.

By: B. Hedan, R. Thomas, A. Motsinger-Reif, J. Abadie, C. Andre, J. Cullen, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Optimization of nonlinear dose- and concentration-response models utilizing evolutionary computation

Dose-Response, 9(3), 387–409.

By: A. Beam & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Pharmacogenomic characterization of US FDA-approved cytotoxic drugs

Pharmacogenomics, 12(10), 1407–1415.

By: E. Peters, A. Motsinger-Reif, T. Havener, L. Everitt, N. Hardison, V. Watson, M. Wagner, K. Richards, M. Province, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Quality of reporting on randomised controlled trials of auriculotherapy for pain

Acupuncture in Medicine, 29(2), 122–126.

By: G. Asher, A. Motsinger-Reif, D. Jonas & A. Viera

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas

Leukemia & Lymphoma, 52(7), 1321–1335.

By: R. Thomas, E. Seiser, A. Motsinger-Reif, L. Borst, V. Valli, K. Kelley, S. Suter, D. Argyle ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Shift work in nurses: Contribution of phenotypes and genotypes to adaptation

PLoS One, 6(4).

By: K. Gamble, A. Motsinger-Reif, A. Hida, H. Borsetti, S. Servick, C. Ciarleglio, S. Robbins, J. Hicks ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

The Effect of Retrospective Sampling on Estimates of Prediction Error for Multifactor Dimensionality Reduction

Annals of Human Genetics, 75, 46–61.

By: S. Winham & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways

Placenta, 32(2), 175–182.

By: S. Tsai, N. Hardison, A. James, A. Motsinger-Reif, S. Bischoff, B. Thames, J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

A comparison of internal validation techniques for multifactor dimensionality reduction

BMC Bioinformatics, 11.

By: S. Winham, A. Slater & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2010 review

Auriculotherapy for pain management: A systematic review and meta-analysis of randomized controlled trials

Journal of Alternative and Complementary Medicine.

By: G. Asher, D. Jonas, R. Coeytaux, A. Reilly, Y. Loh, A. Motsinger-Reif, S. Winham

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Discussion of a genome-wide association approach to determine HIV-1 set point in African Americans

Journal of Infectious Diseases, 201(8), 1118–1120.

By: A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: An AIDS clinical trials group study

Journal of Infectious Diseases, 202(5), 717–722.

By: H. Ribaudo, H. Liu, M. Schwab, E. Schaeffeler, M. Eichelbaum, A. Motsinger-Reif, M. Ritchie, U. Zanger ...

Source: NC State University Libraries
Added: August 6, 2018

2010 conference paper

Grammatical evolution decision trees for detecting gene-gene interactions

In Evolutionary computation, machine learning and data mining in bioinformatics, proceedings (Vol. 6023, pp. 98–109).

By: S. Deodhar & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Polymorphisms in IL-1 beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

BMC Medical Genetics, 11.

By: A. Motsinger-Reif, P. Antas, N. Oki, S. Levy, S. Holland & T. Sterling

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

Blood, 115(18), 3827–3834.

By: N. Limdi, M. Wadelius, L. Cavallari, N. Eriksson, D. Crawford, M. Lee, C. Chen, A. Motsinger-Reif ...

Source: NC State University Libraries
Added: August 6, 2018

2009 article

A A comparison of analytical methods for genetic association studies (vol 32, pg 767, 2008)

Genetic Epidemiology.

By: A. Motsinger-Reif, D. Reif, T. Fanelli & M. Ritchie

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Characterization of conserved and nonconserved imprinted genes in swine

Biology of Reproduction, 81(5), 906–920.

By: S. Bischoff, S. Tsai, N. Hardison, A. Motsinger-Reif, B. Freking, D. Nonneman, G. Rohrer, J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination

Genes and Immunity, 10(2), 112–119.

By: D. Reif, A. Motsinger-Reif, B. McKinney, M. Rock, J. Crowe & J. Moore

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

A A Comparison of analytical methods for genetic association studies

Genetic Epidemiology, 32(8), 767–778.

By: A. Motsinger-Reif, D. Reif, T. Fanelli & M. Ritchie

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Comparison of approaches for machine-learning optimization of neural networks for detecting gene-gene interactions in genetic epidemiology

Genetic Epidemiology, 32(4), 325–340.

By: A. Motsinger-Reif, S. Dudek, L. Hahn & M. Ritchie

Source: NC State University Libraries
Added: August 6, 2018