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2024 journal article
Taxanorm: a novel taxa-specific normalization approach for microbiome data
BMC BIOINFORMATICS, 25(1).
2023 journal article
Guided optimization of ToxPi model weights using a Semi-Automated approach
COMPUTATIONAL TOXICOLOGY, 29.
2023 journal article
MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients
PHARMACEUTICALS, 16(5).
2023 journal article
Pharmacogenomic Analyses Implicate B Cell Developmental Status and MKL1 as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy
CELLS, 12(12).
2023 journal article
RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients
PHARMACEUTICALS, 16(5).
2022 journal article
Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(18).
2022 journal article
Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response
Public Health Reports, 137(4), 803–812.
2022 journal article
Correlation Analysis of Variables From the Atherosclerosis Risk in Communities Study
FRONTIERS IN PHARMACOLOGY, 13.
2022 article
Genomic map of candidate human imprint control regions: the imprintome
Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS, Vol. 6.
2022 journal article
The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells
PLOS ONE, 17(10).
2022 article
ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
Fleming, J., Marvel, S. W., Supak, S., Motsinger-Reif, A. A., & Reif, D. M. (2022, April 26). JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, Vol. 4.
2021 journal article
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies
Clinical Pharmacology & Therapeutics, 110(3), 723–732.
2021 article
Extending the lymphoblastoid cell line model for drug combination pharmacogenomics
Green, A. J., Anchang, B., Akhtari, F. S., Reif, D. M., & Motsinger-Reif, A. (2021, May 28). PHARMACOGENOMICS, Vol. 5.
2021 journal article
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs
PLOS GENETICS, 17(8).
Ed(s): F. Vazquez
2021 journal article
Prediction of synergistic drug combinations using PCA-initialized deep learning
BIODATA MINING, 14(1).
2021 personal communication
The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning
Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January).
Contributors: S. Marvel n, J. House* , M. Wheeler *, K. Song n, Y. Zhou n, F. Wright n, W. Chiu *, I. Rusyn *, *, D. Reif n
2020 journal article
Comparative Exposure Assessment Using Silicone Passive Samplers Indicates That Domestic Dogs Are Sentinels To Support Human Health Research
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 54(12), 7409–7419.
2020 journal article
Genetic and environmental risk for lymphoma in boxer dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(5), 2068–2077.
2020 journal article
In vitro iatrogenic hemolysis of canine packed red blood cells during various rapid transfusion techniques
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 31(1), 25–31.
2020 journal article
Knockoff boosted tree for model-free variable selection
BIOINFORMATICS, 37(7), 976–983.
2020 journal article
Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells
SMALL, 16(21).
Contributors: J. House n , E. Bouzos*, K. Fahy *, V. Francisco*, D. Lloyd n, F. Wright n, *, P. Asuri *, K. Wheeler *
2020 journal article
Nonlinear Dose-Response Modeling of High-Throughput Screening Data Using an Evolutionary Algorithm
DOSE-RESPONSE, 18(2).
2020 journal article
Race and smoking status associated with paclitaxel drug response in patient-derived lymphoblastoid cell lines
PHARMACOGENETICS AND GENOMICS, 31(2), 48–52.
2020 journal article
The influence of packed cell volume versus plasma proteins on thromboelastographic variables in canine blood
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 30(4), 418–425.
2019 journal article
A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies
DIABETES, 68(8), 1649–1662.
2019 article
Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts
St John-Williams, L., Mahmoudiandehkordi, S., Arnold, M., Massaro, T., Blach, C., Kastenmueller, G., … Kaddurah-Daouk, R. (2019, October 17). SCIENTIFIC DATA, Vol. 6.
2019 journal article
Cheminformatics approach to exploring and modeling trait-associated metabolite profiles
JOURNAL OF CHEMINFORMATICS, 11.
2019 journal article
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
NATURE COMMUNICATIONS, 10.
2019 journal article
Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking
EPIGENOMICS, 11(13), 1487–1500.
2019 journal article
Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex
CHROMOSOME RESEARCH, 27(3), 179–202.
2019 journal article
Identifying individual risk rare variants using protein structure guided local tests (POINT)
PLOS COMPUTATIONAL BIOLOGY, 15(2).
2019 journal article
Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy
JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(6), 2572–2586.
2019 journal article
Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines
FRONTIERS IN GENETICS, 10.
Contributors: K. Roell n, T. Havener *, D. Reif n , J. Jack n, H. McLeod *, T. Wiltshire *, *
2019 article
Untargeted Metabolomic Profiling Identifies Disease-Specific Pathways in Food Allergy and Asthma
Crestani, E., Leirer, J., Motsinger-Reif, A., Phipatanakul, W., Kaddurah-Daouk, R., & Chatila, T. A. (2019, February). JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol. 143, pp. AB255–AB255.
2019 journal article
Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 145(3), 897–906.
2018 journal article
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
Alzheimer's & Dementia, 15(1), 76–92.
2018 journal article
Gene set analysis methods: A systematic comparison
Biodata Mining, 11.
2018 journal article
Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial
DIABETES CARE, 41(11), 2404–2413.
2018 journal article
Genetic variants in CPA6 and PRPF31 are associated with variation in response to metformin in individuals with type 2 diabetes
Diabetes, 67(7), 1428–1440.
2018 journal article
International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study
Journal of Veterinary Internal Medicine, 32(3), 930–943.
2018 journal article
Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 7(8), 525–533.
2018 journal article
The influence of Neanderthal alleles on cytotoxic response
PEERJ, 6.
2017 review
An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines
[Review of ]. Frontiers in Pharmacology, 8.
2017 article
Assessment of potential miRNA biomarkers of VERO-cell tumorigenicity in a new line (AGMK1-9T7) of African green monkey kidney cells
Teferedegne, B., Rotroff, D. M., Macauley, J., Foseh, G., Lewis, G., Motsinger-Rief, A., & Lewis, A. M., Jr. (2017, October 4). VACCINE, Vol. 35, pp. 5503–5509.
2017 journal article
Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial
PeerJ, 5.
2017 article
Common genetic variants in neurobeachin (nbea) are associated with metformin drug response in individuals with type 2 diabetes in the accord clinical trial
Clinical Pharmacology & Therapeutics, Vol. 101, pp. S9–9.
2017 journal article
Data descriptor: Targeted metabolomics and medication classification data from participants in the ADNI1 cohort
Scientific Data, 4.
2017 journal article
GUT DERIVED BILE ACID METABOLITES CORRELATE WITH STRUCTURAL AND FUNCTIONAL NEUROIMAGING MEASURES IN ALZHEIMER’S DISEASE
Alzheimer's & Dementia, 13(7), P543–P544.
2017 journal article
Gene expression and linkage analysis implicate as a mediator of rituximab resistance
PHARMACOGENOMICS JOURNAL, 18(3), 467–473.
2017 journal article
Genetic Variants in HSD17B3 , SMAD3 , and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes
Clinical Pharmacology & Therapeutics, 103(4), 712–721.
2017 journal article
Metabolic network failures in Alzheimer's disease: A biochemical road map
Alzheimers & Dementia, 13(9), 965–984.
2017 journal article
Metabolic network failures in Alzheimer's disease: A biochemical road map
Alzheimer's & Dementia, 13(9), 965–984.
2017 journal article
Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD
DIABETES CARE, 41(2), 348–355.
2017 journal article
Pharmacogenetic Analysis of the Model-Based Pharmacokinetics of Five Anti-HIV Drugs: How Does This Influence the Effect of Aging?
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 11(2), 226–236.
2017 journal article
Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(1).
2017 journal article
Targeted metabolomics and medication classification data from participants in the ADNI1 cohort
Scientific Data, 4(1).
2017 journal article
The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(4), 206–213.
2017 journal article
The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback
Translational Psychiatry, 7(8), e1193–e1193.
2016 journal article
A European spectrum of pharmacogenomic biomarkers: Implications for clinical pharmacogenomics
PLoS One, 11(9).
2016 journal article
A comparison of DMET Plus microarray and genome-wide technologies by assessing population substructure
PHARMACOGENETICS AND GENOMICS, 26(4), 147–153.
2016 journal article
A genetic response score for hydrochlorothiazide use insights from genomics and metabolomics integration
Hypertension, 68(3), 621-.
2016 journal article
A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies
Pharmacogenetics and Genomics, 26(7), 324–333.
2016 journal article
Association of breed and histopathological grade in canine mast cell tumours
VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 829–839.
Contributors: H. Mochizuki n , n, C. Bettini, S. Moroff & M. Breen n
2016 journal article
Comprehensive genomic characterization of five canine lymphoid tumor cell lines
BMC Veterinary Research, 12.
2016 journal article
Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes
METABOLOMICS, 12(11).
Contributors: C. Scott Chialvo *, R. Che n, D. Reif n , n & L. Reed *
2016 review
Embracing integrative multiomics approaches
[Review of ]. International Journal of Genomics.
2016 journal article
GENETIC INFLUENCE ON LEVELS OF TARGETED METABOLITES ASSOCIATED WITH ALZHEIMER’S DISEASE
Alzheimer's & Dementia, 12(7), P164–P165.
2016 journal article
Genetic predictors of cardiovascular mortality during intensive glycemic control in type 2 diabetes: Findings from the ACCORD clinical trial
Diabetes Care, 39(11), 1915–1924.
2016 journal article
Genome-wide association study in immunocompetent patients with delayed hypersensitivity to sulfonamide antimicrobials
PLoS One, 11(6).
2016 journal article
INDICES OF PLASMALOGEN BIOSYNTHESIS IN ADNI-1 BASELINE SERUM SAMPLES: ASSOCIATION WITH PROGRESSION TO DEMENTIA IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT
Alzheimer's & Dementia, 12(7), P879–P880.
2016 journal article
Incorporating concomitant medications into genome-wide analyses for the study of complex disease and drug response
Frontiers in Genetics, 7.
2016 journal article
Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero
BMC Genomics, 17.
2016 journal article
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants
Translational Psychiatry, 6(9), e894–e894.
2016 journal article
Pharmacometabolomic assessment of metformin in non-diabetic, African Americans
Frontiers in Pharmacology, 7.
2016 journal article
THE ALZHEIMER’S METABOLOME: RELATIONSHIP TO PATHOLOGICAL MARKERS AND COGNITIVE DECLINE IN THE ALZHEIMER’S DISEASE NEUROIMAGING INITIATIVE (ADNI)
Alzheimer's & Dementia, 12(7), P164.
2016 journal article
Thromboelastographic monitoring of the effect of unfractionated heparin in healthy dogs
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 27(1), 71–81.
2016 journal article
Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(7), 693–699.
2016 journal article
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
Nature Genetics, 48(9), 1055–1059.
2016 journal article
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
Nature Genetics, 48(9), 1055-.
2016 journal article
alpha-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance
DIABETES CARE, 39(6), 988–995.
2015 journal article
Accuracy of SNPs to predict risk of HLA alleles associated with drug-induced hypersensitivity events across racial groups
PHARMACOGENOMICS, 16(8), 817–824.
2015 journal article
An investigation of gene-gene interactions in dose-response studies with Bayesian nonparametrics
Biodata Mining, 8.
2015 journal article
Canine urothelial carcinoma: genomically aberrant and comparatively relevant
Chromosome Research, 23(2), 311–331.
Contributors: S. Shapiro n, S. Raghunath n, C. Williams n, n, J. Cullen n, T. Liu*, D. Albertson*, M. Ruvolo*
2015 journal article
Carboplatin/taxane-induced gastrointestinal toxicity: a pharmacogenomics study on the SCOTROC1 trial
PHARMACOGENOMICS JOURNAL, 16(3), 243–248.
2015 journal article
Evaluating the role of admixture in cancer therapy via in vitro drug response and multivariate genome-wide associations
PHARMACOGENOMICS, 16(13), 1451–1463.
2015 journal article
Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation
Chromosome Research, 23(4), 681–708.
Contributors: S. Roode n, D. Rotroff n, A. Avery *, S. Suter n, D. Bienzle *, J. Schiffman *, n, M. Breen n
2015 journal article
Initial evaluation of nighttime restlessness in a naturally occurring canine model of osteoarthritis pain
PeerJ, 3.
2015 journal article
Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes
CPT: Pharmacometrics & Systems Pharmacology, 4(11), 669–679.
2015 journal article
Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study
ENVIRONMENTAL HEALTH PERSPECTIVES, 123(5), 458–466.
2015 journal article
Relative Quantification and Higher-Order Modeling of the Plasma Glycan Cancer Burden Ratio in Ovarian Cancer Case-Control Samples
JOURNAL OF PROTEOME RESEARCH, 14(10), 4394–4401.
2014 journal article
A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs?
British Journal of Haematology, 167(1), 110–120.
2014 journal article
An adaptive permutation approach for genome-wide association study: Evaluation and recommendations for use
Biodata Mining, 7.
2014 journal article
Bayesian neural networks for detecting epistasis in genetic association studies
BMC Bioinformatics, 15.
2014 journal article
Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24
PLoS Genetics, 10(2).
2014 journal article
Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization
CHROMOSOME RESEARCH, 23(2), 171–186.
2014 journal article
Evaluation of thromboelastography for prediction of clinical bleeding in thrombocytopenic dogs after total body irradiation and hematopoietic cell transplantation
AMERICAN JOURNAL OF VETERINARY RESEARCH, 75(5), 425–432.
2014 journal article
Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy
BREAST CANCER RESEARCH AND TREATMENT, 145(1), 245–254.
2014 journal article
Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines
PHARMACOGENOMICS, 15(2), 137–146.
2014 journal article
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma
CHROMOSOME RESEARCH, 22(3), 305–319.
Contributors: R. Thomas n, L. Borst n , D. Rotroff n, n, K. Lindblad-Toh *, J. Modiano *, M. Breen n
2014 journal article
Lymphoblastoid Cell Lines Models of Drug Response: Successes and Lessons from this Pharmacogenomic Model
CURRENT MOLECULAR MEDICINE, 14(7), 833–840.
2014 journal article
Operative factors associated with short-term outcome in horses with large colon volvulus: 47 cases from 2006 to 2013
Equine Veterinary Journal, 47(3), 279–284.
Contributors: L. Gonzalez n , C. Fogle n , W. Baker, F. Hughes*, J. Law n, n, A. Blikslager n
2014 journal article
PGxClean: a quality control GUI for the Affymetrix DMET chip and other candidate gene studies with non-biallelic alleles
Biodata Mining, 7.
2014 journal article
Relationship Between Mechanical Thresholds and Limb Use in Dogs With Coxofemoral Joint OA-Associated Pain and the Modulating Effects of Pain Alleviation From Total Hip Replacement on Mechanical Thresholds
VETERINARY SURGERY, 43(5), 542–548.
2014 journal article
Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 23(10), 2192–2195.
2013 journal article
Alfaxalone anesthesia in bullfrogs (Lithobates catesbeiana) by injection or immersion
Journal of Zoo and Wildlife Medicine, 44(4), 965–971.
2013 journal article
Alterations in metabolic pathways and networks in Alzheimer’s disease
Translational Psychiatry, 3(4), e244–e244.
2013 journal article
CYP2C8*3 increases risk of neuropathy in breast cancer patients treated with paclitaxel
ANNALS OF ONCOLOGY, 24(6), 1472–1478.
2013 journal article
Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas
Placenta, 34(7), 599–605.
2013 journal article
Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Cancer Research, 73(16), 5029–5039.
Contributors: K. Richards n, n, H. Chen n, Y. Fedoriw n, C. Fan n, D. Nielsen n , G. Small n, R. Thomas n
2013 journal article
Gene selection and cancer type classification of diffuse large-B-cell lymphoma using a bivariate mixture model for two-species data
Human Genomics, 7.
2013 journal article
Genome-wide association studies in pharmacogenomics: Successes and lessons
Pharmacogenetics and Genomics, 23(8), 383–394.
2013 journal article
Interview A discussion on genome-wide associations in pharmacogenomics
Pharmacogenomics, 14(4), 361–363.
2013 article
Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine
Rotroff, D. M., Thomas, R., Breen, M., & Motsinger-Reif, A. A. (2013, December). PHARMACOGENOMICS, Vol. 14, pp. 1929–1931.
Contributors: D. Rotroff n, R. Thomas n, M. Breen n & n
2013 journal article
Prevalence of onychectomy in cats presented for veterinary care near Raleigh, NC and educational attitudes toward the procedure
Veterinary Anaesthesia and Analgesia, 41(1), 48–53.
2013 journal article
Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction
Biodata Mining, 6.
2013 journal article
VH1-44 gene usage defines a subset of canine B-cell lymphomas associated with better patient survival
Veterinary Immunology and Immunopathology, 157(3-4), 125–130.
2012 journal article
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT
PHARMACOGENETICS AND GENOMICS, 22(11), 796–802.
2012 journal article
A predictive model for Efavirenz dosing
Pharmacogenomics, 13(2), 137–138.
2012 journal article
Assessing the utility of whole genome amplified DNA as a template for DMET Plus array
Clinical Chemistry and Laboratory Medicine, 50(8), 1329–1334.
2012 journal article
CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel
BREAST CANCER RESEARCH AND TREATMENT, 134(1), 401–410.
2012 article
Comparison of venous sampling methods for thromboelastography in clinically normal dogs
Walker, J. M., Hanel, R. M., Hansen, B. D., & Motsinger-Reif, A. A. (2012, December). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 73, pp. 1864–1870.
2012 article
Effects of acepromazine maleate on platelet function assessed by use of adenosine diphosphate activated- and arachidonic acid-activated modified thromboelastography in healthy dogs
Conner, B. J., Hanel, R. M., Hansen, B. D., Motsinger-Reif, A. A., Asakawa, M., & Swanson, C. R. (2012, May). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 73, pp. 595–601.
2012 journal article
Evaluation of Polymorphisms in the Sulfonamide Detoxification Genes CYB5A and CYB5R3 in Dogs with Sulfonamide Hypersensitivity
JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(5), 1126–1133.
2012 journal article
Evaluation of polymorphisms in the sulfonamide detoxification genes NAT2, CYB5A, and CYB5R3 in patients with sulfonamide hypersensitivity
PHARMACOGENETICS AND GENOMICS, 22(10), 733–740.
2012 journal article
Loss of Power in Two-Stage Residual-Outcome Regression Analysis in Genetic Association Studies
Genetic Epidemiology, n/a-n/a.
2012 personal communication
Loss of power in two-stage residual-outcome regression analysis in genetic association studies
2012 journal article
Multivariate methods and software for association mapping in dose-response genome-wide association studies
Biodata Mining, 5.
2012 journal article
Positive association between a glutathione-S-transferase polymorphism and lymphoma in dogs
VETERINARY AND COMPARATIVE ONCOLOGY, 12(3), 227–236.
2012 journal article
Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota
MBIO, 3(6).
2011 journal article
A Comparison of Multifactor Dimensionality Reduction and L-1-Penalized Regression to Identify Gene-Gene Interactions in Genetic Association Studies
STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY, 10(1).
2011 journal article
Characterization of Canine Osteosarcoma by Array Comparative Genomic Hybridization and RT-qPCR: Signatures of Genomic Imbalance in Canine Osteosarcoma Parallel the Human Counterpart
GENES CHROMOSOMES & CANCER, 50(11), 859–874.
Contributors: A. Angstadt n, n, R. Thomas n, W. Kisseberth *, C. Guillermo Couto *, D. Duval *, D. Nielsen n , J. Modiano *, M. Breen n
2011 journal article
Genomic Profiling in CEPH Cell Lines Distinguishes between the Camptothecins and Indenoisoquinolines
MOLECULAR CANCER THERAPEUTICS, 10(10), 1839–1845.
2011 journal article
Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees
PLoS One, 6(5).
2011 journal article
Insights into the inhibition of platelet activation by omega-3 polyunsaturated fatty acids: Beyond aspirin and clopidogrel
THROMBOSIS RESEARCH, 128(4), 335–340.
2011 journal article
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer
British Journal of Cancer, 105(11), 1654–1662.
2011 journal article
Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior
BMC Cancer, 11.
2011 journal article
Optimization of nonlinear dose- and concentration-response models utilizing evolutionary computation
Dose-Response, 9(3), 387–409.
2011 journal article
Pharmacogenomic characterization of US FDA-approved cytotoxic drugs
PHARMACOGENOMICS, 12(10), 1407–1415.
2011 journal article
Quality of reporting on randomised controlled trials of auriculotherapy for pain
ACUPUNCTURE IN MEDICINE, 29(2), 122–126.
2011 journal article
Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas
Leukemia & Lymphoma, 52(7), 1321–1335.
2011 journal article
Shift work in nurses: Contribution of phenotypes and genotypes to adaptation
PLoS One, 6(4).
2011 journal article
The Effect of Retrospective Sampling on Estimates of Prediction Error for Multifactor Dimensionality Reduction
Annals of Human Genetics, 75, 46–61.
2010 journal article
A comparison of internal validation techniques for multifactor dimensionality reduction
BMC Bioinformatics, 11.
2010 review
Auriculotherapy for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
[Review of ]. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 16(10), 1097–1108.
2010 article
Discussion of a Genome-Wide Association Approach to Determine HIV-1 Set Point in African Americans
Motsinger-Reif, A. A. (2010, April 15). JOURNAL OF INFECTIOUS DISEASES, Vol. 201, pp. 1118–1120.
2010 journal article
Effect of CYP2B6, ABCB1, and CYP3A5 Polymorphisms on Efavirenz Pharmacokinetics and Treatment Response: An AIDS Clinical Trials Group Study
JOURNAL OF INFECTIOUS DISEASES, 202(5), 717–722.
2010 chapter
Grammatical Evolution Decision Trees for Detecting Gene-Gene Interactions
In Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (pp. 98–109).
2010 conference paper
Grammatical evolution decision trees for detecting gene-gene interactions
Evolutionary computation, machine learning and data mining in bioinformatics, proceedings, 6023, 98–109.
2010 journal article
Polymorphisms in IL-1 beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis
BMC Medical Genetics, 11.
2010 journal article
Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways
PLACENTA, 32(2), 175–182.
2010 journal article
Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups
BLOOD, 115(18), 3827–3834.
2009 article
A Comparison of Analytical Methods for Genetic Association Studies (vol 32, pg 767, 2008)
Motsinger-Reif, A. A., Reif, D. M., Fanelli, T. J., & Ritchie, M. D. (2009, December). GENETIC EPIDEMIOLOGY, Vol. 33, pp. 751–751.
Contributors: D. Reif* , T. Fanelli* & M. Ritchie * n,
2009 journal article
Characterization of Conserved and Nonconserved Imprinted Genes in Swine
BIOLOGY OF REPRODUCTION, 81(5), 906–920.
2008 journal article
262: Molecular signatures of preeclampsia in human term placentas
American Journal of Obstetrics and Gynecology, 199(6), S84.
2008 journal article
A Comparison of Analytical Methods for Genetic Association Studies
GENETIC EPIDEMIOLOGY, 32(8), 767–778.
Contributors: D. Reif* , T. Fanelli* & M. Ritchie * n,
2008 journal article
Comparison of approaches for machine-learning optimization of neural networks for detecting gene-gene interactions in genetic epidemiology
GENETIC EPIDEMIOLOGY, 32(4), 325–340.
2008 journal article
Genetic Basis for Adverse Events after Smallpox Vaccination
The Journal of Infectious Diseases, 198(1), 16–22.
Contributors: D. Reif* , B. McKinney *, A. Motsinger *, S. Chanock *, K. Edwards *, M. Rock*, J. Moore, J. Crowe Jr.
2008 journal article
Hemochromatosis Gene Polymorphisms, Mitochondrial Haplogroups, and Peripheral Lipoatrophy during Antiretroviral Therapy
The Journal of Infectious Diseases, 197(6), 858–866.
2008 journal article
Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination
GENES AND IMMUNITY, 10(2), 112–119.
Contributors: D. Reif* , n, B. McKinney *, M. Rock*, J. Crowe Jr. & J. Moore *
2007 journal article
A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction
Genetic Epidemiology, 31(4), 306–315.
2007 journal article
Genetic heterogeneity is not as threatening as you might think
Genetic Epidemiology, 31(7), 797–800.
2007 journal article
Human Genomic Association Studies: A Primer for the Infectious Diseases Specialist
The Journal of Infectious Diseases, 195(12), 1737–1744.
2007 journal article
Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation
Heart Rhythm, 4(6), 743–749.
2006 chapter
Comparison of Neural Network Optimization Approaches for Studies of Human Genetics
In F. Rothlauf (Ed.), Applications of Evolutionary Computing. EvoWorkshops 2006 (pp. 103–114).
Ed(s): F. Rothlauf
2006 journal article
Complex gene–gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes
Neurogenetics, 8(1), 11–20.
2006 journal article
Drug Transporter and Metabolizing Enzyme Gene Variants and Nonnucleoside Reverse-Transcriptase Inhibitor Hepatotoxicity
Clinical Infectious Diseases, 43(6), 779–782.
2006 journal article
Genetic programming neural networks: A powerful bioinformatics tool for human genetics
Applied Soft Computing, 7(1), 471–479.
2006 journal article
Genetic variation in the mitochondrial enzyme carbamyl-phosphate synthetase I predisposes children to increased pulmonary artery pressure following surgical repair of congenital heart defects: A validated genetic association study
Mitochondrion, 7(3), 204–210.
2006 journal article
Immunogenetics of CD4 Lymphocyte Count Recovery during Antiretroviral Therapy: An AIDS Clinical Trials Group Study
The Journal of Infectious Diseases, 194(8), 1098–1107.
2006 journal article
Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans
Genes & Immunity, 7(4), 310–315.
2006 journal article
The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction
Genetic Epidemiology, 30(6), 546–555.
2005 chapter
Can Neural Network Constraints in GP Provide Power to Detect Genes Associated with Human Disease?
In F. Rothlauf (Ed.), Applications of Evolutionary Computing. EvoWorkshops 2005 (pp. 44–53).
Ed(s): F. Rothlauf
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