Works (3)
Updated: July 5th, 2023 15:39
2020 journal article
Engineering Cercospora disease resistance via expression of Cercospora nicotianae cercosporin-resistance genes and silencing of cercosporin production in tobacco
PLOS ONE, 15(3), e0230362.
Ed(s): R. Wilson
MeSH headings : Ascomycota / drug effects; Ascomycota / genetics; Disease Resistance / drug effects; Disease Resistance / genetics; Drug Resistance, Fungal / drug effects; Drug Resistance, Fungal / genetics; Gene Expression Regulation, Fungal / drug effects; Gene Silencing / drug effects; Genes, Fungal; Genetic Engineering; Perylene / analogs & derivatives; Perylene / pharmacology; Plants, Genetically Modified; Tobacco / microbiology; Transformation, Genetic; Transgenes
TL;DR:
It is concluded that expression of fungal cercosporin autoresistance genes as well as silencing of the cercsporin pathway are both effective strategies for engineering resistance to Cercospora diseases where cercOSporin plays a critical role.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 8, 2020
2015 journal article
Characterization of Cercospora nicotianae Hypothetical Proteins in Cercosporin Resistance
PLOS ONE, 10(10).
MeSH headings : Ascomycota / genetics; Ascomycota / metabolism; Drug Resistance, Fungal / drug effects; Fungal Proteins / genetics; Fungal Proteins / metabolism; Gene Expression Regulation, Fungal / drug effects; Mutation; Neurospora crassa / genetics; Neurospora crassa / metabolism; Perylene / analogs & derivatives; Perylene / pharmacology
TL;DR:
Analysis of 71cR conserved domains and secondary and tertiary structure identify the protein as having an NTF2-like superfamily DUF1348 domain with unknown function, to be intracellular and localized in the cytosol, and to have similarities to proteins in the steroid delta-isomerase family.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Membrane transporters in self resistance of Cercospora nicotianae to the photoactivated toxin cercosporin
Current Genetics, 61(4), 601–620.
author keywords: Perylenequinone; Photosensitizer resistance; ABC transporter; MFS transporter; Targeted gene disruption; CRG1; CnATR1; CnCFP
MeSH headings : ATP-Binding Cassette Transporters / genetics; ATP-Binding Cassette Transporters / metabolism; Antifungal Agents / metabolism; Antifungal Agents / pharmacology; Drug Resistance, Fungal / genetics; Fungal Proteins / genetics; Fungal Proteins / metabolism; Gene Expression Regulation, Fungal; Gene Targeting; Membrane Transport Proteins / genetics; Membrane Transport Proteins / metabolism; Neurospora crassa / drug effects; Neurospora crassa / genetics; Neurospora crassa / metabolism; Perylene / analogs & derivatives; Perylene / metabolism; Perylene / pharmacology; Photosensitizing Agents / metabolism; Photosensitizing Agents / pharmacology; Phylogeny; Saccharomycetales / classification; Saccharomycetales / drug effects; Saccharomycetales / genetics; Saccharomycetales / metabolism; Singlet Oxygen / metabolism; Uracil / metabolism; Zinc / metabolism
TL;DR:
It is concluded that cercosporin autoresistance in Cercospora is mediated by multiple genes, and that the fungus compensates for mutations by up-regulation of other resistance genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
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