@article{a clinico-pathological analysis of ivermectin-induced toxicity in eight hermann’s tortoises treated for tick infestation_2024, url={https://publons.com/wos-op/publon/67695733/}, DOI={10.5455/JRVS.20240328090505}, abstractNote={This study presents a clinico-pathological examination of ivermectin-induced toxicity in eight Hermann's tortoises, administered to address tick infestation. Subsequently, nervous signs were observed, leading to the demise of five tortoises. Clinical manifestations included inappetence, weakness, diarrhea, tremors, and paralysis preceding death. Postmortem examination revealed hemorrhagic lung tissues, fatty liver, and significant tick infestation. Laboratory analysis detected Borrelia spp. in blood smears, Oxyuris spp. eggs and cysts in fecal samples, and Escherichia coli and Salmonella enterica in microbial cultures. Histopathological analysis indicated hepatic vacuolar degeneration. The correlation between clinical, pathological, and histopathological findings suggests acute infection and drug toxicity, particularly ivermectin toxicity. The tortoises, initially weighing an average of 900 grams, were pets at Niger Resort Minna and were presented to the Nigerian Police Veterinary Hospital, Garki 2 on the 27th of May 2023, after exhibiting symptoms of inappetence and severe diarrhea following the administration of 1% ivermectin (Ivanor from Jubaili Animal Health Ltd) at a dose rate of 0.04 mg/kg. Three tortoises died shortly after administration, with two succumbing within hours.}, journal={Journal of Research in Veterinary Sciences}, year={2024} } @article{a_binhambali_umar_mukhtar_a_pate_nuhu_ipinlaiye_kolo_ismail_et al._2024, title={Exploring the Effects of Glutathione Supplementation on Liver Enzymes and Serum Electrolyte Levels in Mice Exposed to 850-1900 MHz Mobile Phone Radiation: An Investigation into Radiative Stress and Potential Protective Measures}, url={https://doi.org/10.1101/2024.05.24.595675}, DOI={10.1101/2024.05.24.595675}, abstractNote={ABSTRACT The pervasive presence of electromagnetic fields (EMF) generated by modern technologies poses a significant threat to human health, with ionizing radiation, a byproduct of EMF, potentially contributing to cancer development. This study explores the impact of chronic exposure to GSM-EMFs and 900-1800 MHz-induced electromagnetic radiation (EMR) on liver enzymes, and serum electrolytes in mice and potential mitigating effect of exogenous glutathione administration. Thirty-five adult male mice were randomly divided into seven groups and exposed to various modes of mobile phone radiation for five weeks, with or without glutathione administration. Liver enzymes (ALP, ALT, AST) and serum electrolytes (sodium, potassium, bicarbonate) were analyzed. Results showed significant increases in ALP levels in the Silent, Ringtone + GSH, and Silent + GSH groups compared to controls, while ALT and AST levels remained largely unchanged. Serum electrolyte concentrations did not significantly differ across experimental groups.}, journal={BioRxiv}, author={A, Aliyah T and Binhambali, Abdulhakeem and Umar, AH and Mukhtar, Abubakar Ibrahim and A, Tekanyi A and Pate, AA and Nuhu, A and Ipinlaiye, T and Kolo, Haruna Muhammad and Ismail, Ummulkhairi and et al.}, year={2024}, month={May} } @inproceedings{binhambali_bada_2019, title={MANAGEMENT OF BABESIOSIS IN A 5-YEAR-OLD CAUCASIAN DOG}, url={https://rgdoi.net/10.13140/RG.2.2.32165.10729}, DOI={10.13140/RG.2.2.32165.10729}, booktitle={Unpublished}, publisher={Unpublished}, author={Binhambali, Abdulhakeem and Bada, Abdulaziz Abdullahi}, year={2019} }