Alexandra Bryant

College of Sciences

Works (1)

Updated: April 5th, 2024 18:46

2024 article

Exploring the Landscape of Aptamers: From Cross-Reactive to Selective to Specific, High-Affinity Receptors for Cocaine

Yang, K., Alkhamis, O., Canoura, J., Bryant, A., Gong, E. M., Barbu, M., … Landry, D. W. (2024, February 13). JACS AU, Vol. 2.

By: K. Yang*, O. Alkhamis n, J. Canoura n, A. Bryant n, E. Gong*, M. Barbu*, S. Taylor*, D. Nikic* ...

author keywords: cocaine; aptamer; specific; high-affinity; cross-reactive; hydrophobic receptor
TL;DR: A series of progressively improved DNA aptamers recognizing cocaine are reported, with the final optimized receptors having low nanomolar affinity and over a thousand-fold selectivity over the initial cross-reactants. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: March 11, 2024

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