Works (8)

Updated: July 5th, 2023 15:47

2019 journal article

Optimization of Sequence, Display, and Mode of Operation of IgG-Binding Peptide Ligands to Develop Robust, High-Capacity Affinity Adsorbents That Afford High IgG Product Quality

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(1).

By: T. Islam n, A. Naik n, Y. Hashimoto*, S. Menegatti n & R. Carbonell n

co-author countries: Japan 🇯🇵
author keywords: affinity chromatography; peptide ligand; antibody purification; binding capacity; process optimization; aggregate removal
Sources: Web Of Science, ORCID
Added: March 11, 2019

2017 journal article

Design, selection, and development of cyclic peptide ligands for human erythropoietin

JOURNAL OF CHROMATOGRAPHY A, 1500, 105–120.

By: W. Kish n, H. Sachi*, A. Naik n, M. Roach n, B. Bobay n, R. Blackburn n, S. Menegatti n, R. Carbonell n

co-author countries: Japan 🇯🇵
author keywords: Erythropoietin; Cyclic peptide ligands; Ligand screening; Affinity chromatography; Affinity maturation; In-silico docking
MeSH headings : Amino Acid Sequence; Amino Acids / chemistry; Erythropoietin / chemistry; Humans; Kinetics; Ligands; Molecular Sequence Data; Peptides, Cyclic / chemistry; Peptides, Cyclic / isolation & purification; Protein Binding
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Peptide-based affinity adsorbents with high binding capacity for the purification of monoclonal antibodies

Industrial & Engineering Chemistry Research, 52(26), 8800–8811.

By: W. Kish n, A. Naik n, S. Menegatti n & R. Carbonell n

Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Reversible cyclic peptide libraries for the discovery of affinity ligands

Analytical Chemistry, 85(19), 9229–9237.

By: S. Menegatti n, K. Ward n, A. Naik n, W. Kish n, R. Blackburn n & R. Carbonell n

MeSH headings : Ligands; Molecular Structure; Peptide Library; Peptides, Cyclic / analysis; Tandem Mass Spectrometry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands

Biotechnology and Bioengineering, 110(3), 857–870.

By: S. Menegatti n, M. Hussain n, A. Naik n, R. Carbonell n & B. Rao n

author keywords: cyclic peptide; mRNA display; Fc binding; affinity ligand; library
MeSH headings : Humans; Immunoglobulin Fc Fragments / metabolism; Peptide Library; Peptides, Cyclic / chemistry; Peptides, Cyclic / genetics; Peptides, Cyclic / isolation & purification; Peptides, Cyclic / metabolism; Protein Binding; Protein Engineering / methods; RNA, Messenger / genetics; Solid-Phase Synthesis Techniques / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Alkaline-stable peptide ligand affinity adsorbents for the purification of biomolecules

Journal of Chromatography A, 1245, 55–64.

By: S. Menegatti n, A. Naik n, P. Gurgel n & R. Carbonell n

author keywords: Peptide ligand; Affinity adsorbent; NaOH stability; Modification of surface chemistry; Solid-phase peptide synthesis; Cleaning-in-place
MeSH headings : Adsorption; Alkalies / chemistry; Chromatography, Affinity / instrumentation; Chromatography, Affinity / methods; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Ligands; Peptides / chemistry; Protein Binding
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Process for purification of monoclonal antibody expressed in transgenic Lemna plant extract using dextran-coated charcoal and hexamer peptide affinity resin

Journal of Chromatography A, 1260, 61–66.

By: A. Naik n, S. Menegatti n, H. Reese n, P. Gurgel n & R. Carbonell n

author keywords: Dextran-coated charcoal; Transgenic plants; Hexapeptide ligand; IgG purification; Monoclonal antibody; Phenolics; Lemna minor
MeSH headings : Antibodies, Monoclonal / isolation & purification; Antibodies, Monoclonal / metabolism; Araceae / chemistry; Araceae / metabolism; Charcoal / chemistry; Chromatography, Affinity / methods; Dextrans / chemistry; Humans; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Peptides / chemistry; Peptides / metabolism; Plant Extracts / chemistry; Plants, Genetically Modified / chemistry; Plants, Genetically Modified / metabolism; Protein Binding; Staphylococcal Protein A / chemistry; Staphylococcal Protein A / isolation & purification
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media

Journal of Chromatography A, 1218(13), 1691–1700.

By: A. Naik n, S. Menegatti n, P. Gurgel n & R. Carbonell n

author keywords: Hexapeptide ligand; IgG purification; Monoclonal antibody; Affinity chromatography; Regeneration
MeSH headings : Adsorption; Animals; Antibodies, Monoclonal / chemistry; Antibodies, Monoclonal / isolation & purification; CHO Cells; Caprylates; Cell Culture Techniques; Chromatography, Affinity / methods; Cricetinae; Cricetulus; Culture Media; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Oligopeptides / chemistry; Phosphoric Acids; Protein Binding; Sodium Chloride; Urea
Sources: Web Of Science, ORCID
Added: August 6, 2018

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