Ashley E. Marlowe

Works (2)

Updated: July 5th, 2023 15:49

2012 article

The effect of point mutations on structure and mechanical properties of collagen-like fibril: A molecular dynamics study

Marlowe, A. E., Singh, A., & Yingling, Y. G. (2012, August 2). Materials Science and Engineering C, Vol. 32, p. 2583–2588.

By: A. Marlowe n, A. Singh n & Y. Yingling n 

Contributors: A. Marlowe n, A. Singh n & Y. Yingling n 

author keywords: Collagen fibril; Molecular dynamics simulations; Point mutations; Osteogenesis Imperfecta; Mechanical properties
topics (OpenAlex): Collagen: Extraction and Characterization; Connective tissue disorders research; Bone and Dental Protein Studies
TL;DR: The results suggest that the reduction in mechanical properties of collagen fibrils may be used to predict the clinical outcome of mutations, as well as the trend in reduction of fibril's tensile strength predicted by simulations. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 article

The Sequence of HIV-1 TAR RNA Helix Controls Cationic Distribution

Sethaphong, L., Singh, A., Marlowe, A. E., & Yingling, Y. G. (2010, January 14). The Journal of Physical Chemistry C, Vol. 114, p. 5506–5512.

By: L. Sethaphong n, A. Singh n, A. Marlowe n & Y. Yingling n 

Contributors: Y. Yingling n , A. Marlowe n, A. Singh n & L. Sethaphong n

topics (OpenAlex): RNA and protein synthesis mechanisms; RNA Research and Splicing; DNA and Nucleic Acid Chemistry
TL;DR: There is a sequence-dependent cationic localization toward the purine-rich run within the TAR helix and other purine -rich duplexes and the behavior is independent of ionic species or a presence of a bulge. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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