Allison Schloop

College of Sciences

Works (3)

Updated: March 29th, 2024 12:50

2020 journal article

Discovery of Membrane-Permeating Cyclic Peptides via mRNA Display

BIOCONJUGATE CHEMISTRY, 31(10), 2325–2338.

By: J. Bowen n, A. Schloop n, G. Reeves*, S. Menegatti n  & B. Rao n

MeSH headings : Animals; Cell Line; Cell-Penetrating Peptides / chemistry; Cell-Penetrating Peptides / genetics; Cell-Penetrating Peptides / pharmacokinetics; Drosophila melanogaster / embryology; Gene Library; Humans; Mice; Models, Molecular; NIH 3T3 Cells; Peptides, Cyclic / chemistry; Peptides, Cyclic / genetics; Peptides, Cyclic / pharmacokinetics; Permeability; RNA, Messenger / genetics
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: December 21, 2020

2020 article

Formation, interpretation, and regulation of the Drosophila Dorsal/NF-kappa B gradient

GRADIENTS AND TISSUE PATTERNING, Vol. 137, pp. 143–191.

By: A. Schloop n, P. Bandodkar n & G. Reeves n

MeSH headings : Animals; Body Patterning; Computational Biology / methods; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / embryology; Drosophila melanogaster / physiology; Embryo, Nonmammalian / cytology; Embryo, Nonmammalian / physiology; Gene Expression Regulation, Developmental; NF-kappa B / genetics; NF-kappa B / metabolism; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Phosphoproteins / genetics; Phosphoproteins / metabolism; Signal Transduction; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: The mechanisms behind the initiation of the Dorsal gradient and its regulation of target genes are described, and a discussion of quantitative and computational studies ofThe Dl gradient system, including regulation of theDl gradient is discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 26, 2020

2020 journal article

Robustness of the Dorsal morphogen gradient with respect to morphogen dosage

PLOS COMPUTATIONAL BIOLOGY, 16(4).

By: H. Al Asafen n, P. Bandodkar n, S. Carrell-Noel n, A. Schloop n, J. Friedman n & G. Reeves n

MeSH headings : Animals; Body Patterning / genetics; Cell Nucleus / metabolism; Cytoplasm / metabolism; DNA-Binding Proteins / metabolism; Drosophila / embryology; Drosophila / genetics; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Embryo, Nonmammalian / metabolism; Gene Expression Regulation, Developmental / genetics; Morphogenesis / genetics; NF-kappa B / metabolism; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Phosphoproteins / genetics; Phosphoproteins / metabolism; Signal Transduction; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: The robustness of the Dorsal/NF-κB signaling module with respect to perturbations to the dosage of maternally-expressed dorsal mRNA is investigated and the need for quantitative understanding of biophysical mechanisms of morphogen gradients in order to understand emergent phenotypes, such as robustness is highlighted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 26, 2020

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