Amy F. Pruitt

Works (14)

Updated: July 5th, 2023 15:58

2012 journal article

Autologous peripheral blood hematopoietic cell transplantation in dogs with B-cell lymphoma

Journal of Veterinary Internal Medicine, 26(5), 1155–1163.

By: J. Willcox, A. Pruitt & S. Suter

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Total skin electron therapy technique for the canine patient

Veterinary Radiology & Ultrasound, 52(3), 345–352.

By: K. Rechner, K. Weeks & A. Pruitt

Source: NC State University Libraries
Added: August 6, 2018

2010 article

CHEMOTHERAPY FOLLOWED BY ABDOMINAL CAVITY IRRADIATION FOR FELINE LYMPHOBLASTIC LYMPHOMA

WILLIAMS, L. A. U. R. E. L. E., PRUITT, A. M. Y. F., & THRALL, D. O. N. A. L. D. E. (2010, August 12). Veterinary Radiology & Ultrasound.

By: L. Williams n, A. Pruitt n & D. Thrall n

author keywords: feline; lymphoma; chemoradiotherapy
MeSH headings : Abdominal Neoplasms / blood; Abdominal Neoplasms / drug therapy; Abdominal Neoplasms / radiotherapy; Abdominal Neoplasms / veterinary; Animals; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Cat Diseases / blood; Cat Diseases / drug therapy; Cat Diseases / radiotherapy; Cats; Combined Modality Therapy / veterinary; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood; Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma / veterinary; Radiotherapy Dosage; Remission Induction / methods; Treatment Outcome
topics (OpenAlex): Veterinary Oncology Research; Hepatocellular Carcinoma Treatment and Prognosis; Lymphoma Diagnosis and Treatment
TL;DR: Results of this study suggest that 15 Gy total abdomen fractionated radiation therapy after induction chemotherapy is tolerated satisfactorily, and this protocol is suitable for further testing to quantify efficacy. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Medical and surgical management of reproductive neoplasia in two western lowland gorillas (Gorilla gorilla gorilla)

Journal of Medical Primatology, 39(5), 328–335.

By: E. Stringer, R. De Voe, F. Valea, S. Toma, G. Mulvaney, A. Pruitt, B. Troan, M. Loomis

Source: NC State University Libraries
Added: August 6, 2018

2010 article

RADIATION THERAPY COMMUNICATION: NASAL PASSAGE AND PARANASAL SINUS LYMPHOMA IN A PONY

GERARD, M. A. T. H. E. W., PRUITT, A. M. Y., & THRALL, D. O. N. A. L. D. E. (2010, January 1). Veterinary Radiology & Ultrasound, Vol. 51, pp. 97–101.

By: M. Gerard n , A. Pruitt n & D. Thrall*

author keywords: equine; lymphoma; nasal passage; paranasal sinus; radiation therapy
MeSH headings : Animals; Euthanasia, Animal; Horse Diseases / pathology; Horse Diseases / radiotherapy; Horses; Lymphoma, B-Cell / pathology; Lymphoma, B-Cell / radiotherapy; Lymphoma, B-Cell / veterinary; Male; Palliative Care / methods; Paranasal Sinus Neoplasms / radiotherapy; Paranasal Sinus Neoplasms / veterinary; Radiation Dosage; Treatment Outcome
topics (OpenAlex): Infectious Diseases and Mycology; Veterinary Oncology Research
TL;DR: The results suggest that localized equine B-cell lymphoma is radiosensitive, and that palliative radiation therapy is a reasonable consideration for large tumors, even when tumor volume prevents all gross tumor from being irradiated. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 article

EFFECT OF WETNESS LEVEL ON THE SUITABILITY OF WET GAUZE AS A SUBSTITUTE FOR SUPERFLAB® AS A BOLUS MATERIAL FOR USE WITH 6 MV PHOTONS

BENOIT, J. E. R. O. M. E., PRUITT, A. M. Y. F., & THRALL, D. O. N. A. L. D. E. (2009, August 21). Veterinary Radiology & Ultrasound.

By: J. Benoit n, A. Pruitt n & D. Thrall n

author keywords: air gap; bolus; radiation therapy; Superflab((R)); surface dose
MeSH headings : Animals; Radiation Dosage; Radiotherapy, High-Energy / veterinary; Skin / radiation effects; Surgical Sponges; Water
topics (OpenAlex): Advanced Radiotherapy Techniques; Radiation Therapy and Dosimetry; Radiation Dose and Imaging
TL;DR: If Superflab use leads to poor contact with the skin, wet gauze having a physical density of 1.02 g/cm3 can be used as a substitute, and the presence of an air gap under SuperFlab led to reduced surface dose, especially for small fields and large air gaps. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumours

Shiomitsu, K., Johnson, C. L., Malarkey, D. E., Pruitt, A. F., & Thrall, D. E. (2009, May 13). Veterinary and Comparative Oncology.

By: K. Shiomitsu n, C. Johnson n, D. Malarkey*, A. Pruitt n & D. Thrall n

author keywords: canine; EGFR; nasal tumour; radiosensitivity; VEGF
MeSH headings : Animals; Dog Diseases / metabolism; Dog Diseases / pathology; Dog Diseases / radiotherapy; Dogs; ErbB Receptors / metabolism; Gene Expression Regulation, Neoplastic; Immunohistochemistry / veterinary; Neoplasms, Glandular and Epithelial / metabolism; Neoplasms, Glandular and Epithelial / pathology; Neoplasms, Glandular and Epithelial / radiotherapy; Neoplasms, Glandular and Epithelial / veterinary; Nose Neoplasms / radiotherapy; Nose Neoplasms / veterinary; Treatment Outcome; Vascular Endothelial Growth Factor A / metabolism
topics (OpenAlex): Veterinary Oncology Research; Angiogenesis and VEGF in Cancer; Infectious Diseases and Mycology
TL;DR: Findings indicate that EGFR and VEGF proteins were present in some malignant epithelial nasal tumours in the dogs, and therefore, it may be beneficial to treat canine patients with tumours that overexpress EG FR and V EGF with specific inhibitors in conjunction with radiation. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 article

CHARACTERIZATION OF NORMAL TISSUE COMPLICATIONS IN 51 DOGS UNDERGOING DEFINITIVE PELVIC REGION IRRADIATION

ARTHUR, J. E. N. N. I. F. E. R. J., KLEITER, M. I. R. I. A. M. M., THRALL, D. O. N. A. L. D. E., & PRUITT, A. M. Y. F. (2008, January 1). Veterinary Radiology & Ultrasound.

By: J. Arthur n, M. Kleiter*, D. Thrall n & A. Pruitt n

author keywords: dog; radiation therapy; normal tissue complication; rectal toxicity
MeSH headings : Animals; Colonic Neoplasms / radiotherapy; Colonic Neoplasms / veterinary; Dog Diseases / epidemiology; Dog Diseases / radiotherapy; Dogs; Female; Male; Necrosis / pathology; Necrosis / veterinary; North Carolina / epidemiology; Pedigree; Pelvis / pathology; Prevalence; Radiation Injuries / epidemiology; Radiation Injuries / veterinary; Radiotherapy Dosage / veterinary; Retrospective Studies
topics (OpenAlex): Veterinary Oncology Research; Cancer Diagnosis and Treatment; Effects of Radiation Exposure
TL;DR: The finding of an association of tumor site to complications may be a spurious finding and the association between field size and complications is not unexpected although absolute difference in field size between dogs with and without complications was small. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 article

A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas

Siddiqui, F., Li, C.-Y., LaRue, S. M., Poulson, J. M., Avery, P. R., Pruitt, A. F., … Hauck, M. L. (2007, January 1). Molecular Cancer Therapeutics.

By: F. Siddiqui  n, C. Li*, S. LaRue *, J. Poulson*, P. Avery *, A. Pruitt n, X. Zhang *, R. Ullrich* ...

MeSH headings : Adenoviridae; Animals; Cats; Cytomegalovirus / genetics; Feasibility Studies; Genetic Therapy / adverse effects; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Hyperthermia, Induced; Interleukin-12 / blood; Interleukin-12 / genetics; Interleukin-12 / therapeutic use; Liver / pathology; Mice; Promoter Regions, Genetic / genetics; Recombinant Proteins / adverse effects; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Recombinant Proteins / therapeutic use; Sarcoma / drug therapy; Sarcoma / genetics; Sarcoma / radiotherapy; Sarcoma / veterinary
topics (OpenAlex): Virus-based gene therapy research; Immunotherapy and Immune Responses; CAR-T cell therapy research
TL;DR: An adenoviral gene therapy vector with IL-12 controlled by a heat-inducible promoter (heat shock promoter 70B) was developed and tested in a phase I clinical trial in cats with spontaneously arising soft tissue sarcoma, finding it possible to localize gene expression and limit systemic toxicity of IL- 12 using the hyperthermia-induced gene therapy approach. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 article

COMPARISON OF ISODOSE DISTRIBUTIONS IN CANINE BRAIN IN HETEROGENEITY‐CORRECTED VERSUS UNCORRECTED TREATMENT PLANS USING 6 MV PHOTONS

LYONS, J., THRALL, D. E., & PRUITT, A. F. (2007, April 19). Veterinary Radiology & Ultrasound.

By: J. Lyons n, D. Thrall n & A. Pruitt n

author keywords: heterogeneity correction; dog; radiation therapy; treatment planning
MeSH headings : Algorithms; Animals; Brain Neoplasms / radiotherapy; Brain Neoplasms / veterinary; Dog Diseases / radiotherapy; Dogs; Dose-Response Relationship, Radiation; Photons; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted / methods; Radiotherapy Planning, Computer-Assisted / veterinary; Radiotherapy, Conformal / methods; Radiotherapy, Conformal / veterinary; Tomography, Emission-Computed, Single-Photon / methods; Tomography, Emission-Computed, Single-Photon / veterinary
topics (OpenAlex): Advanced MRI Techniques and Applications; Advanced Radiotherapy Techniques; MRI in cancer diagnosis
TL;DR: No clinically significant difference is found between CT-based radiotherapy plans without and with heterogeneity correction for brain tumors in small animals, which supports the use of MR-based treatment planning for radiotherapy of small animal brain tumors. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 article

Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas

Thrall, D. E., LaRue, S. M., Pruitt, A. F., Case, B., & Dewhirst, M. W. (2006, January 1). International Journal of Hyperthermia.

By: D. Thrall n, S. LaRue *, A. Pruitt n, B. Case n & M. Dewhirst*

author keywords: hyperthermia; radiation therapy; dog; oxygen measurements
MeSH headings : Animals; Cell Hypoxia / physiology; Cell Hypoxia / radiation effects; Combined Modality Therapy / methods; Combined Modality Therapy / veterinary; Dog Diseases / metabolism; Dog Diseases / therapy; Dogs; Hyperthermia, Induced / methods; Hyperthermia, Induced / veterinary; Oxygen / analysis; Oxygen / metabolism; Sarcoma / metabolism; Sarcoma / therapy; Sarcoma / veterinary
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Sarcoma Diagnosis and Treatment; Virus-based gene therapy research
TL;DR: There was an increase in oxygenation in tumours with low pre-treatment oxygenation that persisted throughout treatment, an advantageous hyperthermia effect as it may lead to increased radiation cell killing at each fraction. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 article

Phase I Trial of Doxorubicin-Containing Low Temperature Sensitive Liposomes in Spontaneous Canine Tumors

Hauck, M. L., LaRue, S. M., Petros, W. P., Poulson, J. M., Yu, D., Spasojevic, I., … Dewhirst, M. W. (2006, July 1). Clinical Cancer Research.

By: M. Hauck n, S. LaRue *, W. Petros *, J. Poulson*, D. Yu, I. Spasojevic, A. Pruitt n, A. Klein n ...

MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / adverse effects; Antineoplastic Agents / pharmacokinetics; Carcinoma / therapy; Carcinoma / veterinary; Combined Modality Therapy; Dog Diseases / therapy; Dogs; Dose-Response Relationship, Drug; Doxorubicin / administration & dosage; Doxorubicin / adverse effects; Doxorubicin / pharmacokinetics; Drug Administration Schedule; Drug Delivery Systems; Female; Hyperthermia, Induced / methods; Liposomes; Male; Maximum Tolerated Dose; Microwaves / therapeutic use; Sarcoma / therapy; Sarcoma / veterinary; Temperature; Treatment Outcome
topics (OpenAlex): RNA Interference and Gene Delivery; Virus-based gene therapy research; Nanoparticle-Based Drug Delivery
TL;DR: LTSL-doxorubicin offers a novel approach to improving drug delivery to solid tumors and was well tolerated and resulted in favorable response profiles in these patients. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy

Clinical Cancer Research, 11(14), 5206–5214.

By: D. Thrall, S. Larue, D. Yu, T. Samulski, L. Sanders, B. Case, G. Rosner, C. Azuma ...

Source: NC State University Libraries
Added: August 6, 2018

2004 article

USE OF PHOTON FIELDS WITH NONCOINCIDENT ISOCENTERS TO IMPROVE HOMOGENEITY OF DOSE DISTRIBUTION

Pruitt, A. F., & Thrall, D. E. (2004, September 1). Veterinary Radiology & Ultrasound.

By: A. Pruitt n & D. Thrall n

author keywords: boost fields; noncoincident isocenters; radiation therapy; dog
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / radiotherapy; Dogs; Nose Neoplasms / radiotherapy; Nose Neoplasms / veterinary; Radiography; Radiotherapy Dosage / veterinary; Radiotherapy Planning, Computer-Assisted / veterinary
topics (OpenAlex): Advanced Radiotherapy Techniques; Medical Imaging Techniques and Applications; Head and Neck Cancer Studies
TL;DR: Improved tumor dose distribution was achieved with the addition of a smaller field having a different isocenter, and dose delivered to the mandible was lower in all dogs with the use of noncoincident fields, as it was possible to reduce the dose delivered from the ventral field. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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