Works (50)

2012 journal article

Human tRNA(UUU)(LYs3) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism

Journal of Molecular Biology, 416(4), 467–485.

By: F. Vendeix, F. Murphy, W. Cantara, G. Leszczynska, E. Gustilo, B. Sproat, A. Malkiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase

RNA, 17(9), 1678–1687.

By: K. Harris, V. Jones, Y. Bilbille, M. Swairjo & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA

Nucleic Acids Research, 38(9), 3094–3105.

By: A. Scheunemann, W. Graham, F. Vendeix & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Free energy calculation of modified base-pair formation in explicit solvent: A predictive model

RNA, 15(12), 2278–2287.

By: F. Vendeix, A. Munoz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

The structure of the human tRNA(Lys3) anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairs

Nucleic Acids Research, 37(10), 3342–3353.

By: Y. Bilbille, F. Vendeix, R. Guenther, A. Malkiewicz, X. Ariza, J. Vilarrasa, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

A disease-causing point mutation in human mitochondrial tRNA(Met) results in tRNA misfolding leading to defects in translational initiation and elongation

Journal of Biological Chemistry, 283(49), 34445–34456.

By: C. Jones, C. Jones, W. Graham, P. Agris & L. Spremulli

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding

Biochemistry, 47(23), 6117–6129.

By: F. Vendeix, A. Dziergowska, E. Gustilo, W. Graham, B. Sproat, A. Malkiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Bringing order to translation: the contributions of transfer RNA anticodon-domain modifications

EMBO Reports, 9(7), 629–635.

By: P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNA(Met)

Nucleic Acids Research, 36(20), 6548–6557.

By: H. Lusic, E. Gustilo, F. Vendeix, R. Kaiser, M. Delaney, W. Graham, V. Moye, W. Cantara, P. Agris, A. Deiters

Source: NC State University Libraries
Added: August 6, 2018

2008 review

tRNA's modifications bring order to gene expression

[Review of ]. Current Opinion in Microbiology, 11(2), 134–140.

By: E. Gustilo, A. Franck & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

E-coli glutamyl-tRNA synthetase is inhibited by anticodon stem-loop domains and a minihelix

RNA Biology, 4(2), 85–92.

By: E. Gustilo, D. Dubois, J. Lapointe & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines

Nature Structural & Molecular Biology, 14(6), 498–502.

By: A. Weixlbaumer, F. Murphy, A. Dziergowska, A. Malkiewicz, F. Vendeix, P. Agris, V. Ramakrishnan

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Quality assessment of commercial small interfering RNA and DNA: Monoclonal antibodies and a high-throughput chemiluminescence assay

Analytical Biochemistry, 360(1), 172–174.

By: L. Barley-Maloney & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Specificity of phage display selected peptides for modified anticodon stem and loop domains of tRNA

Protein Journal, 26(1), 61–73.

By: M. Eshete, M. Marchbank, S. Deutscher, B. Sproat, G. Leszczynska, A. Malkiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2007 review

tRNA's wobble decoding of the genome: 40 years of modification

[Review of ]. Journal of Molecular Biology, 366(1), 1–13.

By: P. Agris, F. Vendeix & W. Graham

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs

Journal of Molecular Biology, 362(4), 771–786.

By: C. Jones, A. Spencer, J. Hsu, L. Spremulli, S. Martinis, M. Derider, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Assembly of the archaeal box C/D sRNP can occur via alternative pathways and requires temperature-facilitated sRNA remodeling

Journal of Molecular Biology, 362(5), 1025–1042.

By: K. Gagnon, X. Zhang, P. Agris & E. Maxwell

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Assessing incomplete deprotection of microarray oligonucleotides in situ

Nucleic Acids Research, 34(19).

By: H. Dressman, L. Barley-Maloney, L. Rowlette, P. Agris & M. Garcia-Blanco

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

tRNA regulation of gene expression: Interactions of an mRNA 5 '-UTR with a regulatory tRNA

RNA, 12(7), 1254–1261.

By: A. Nelson, T. Henkin & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2005 patent

Antibacterial and antiviral agents and methods of screening for the same

Washington, DC: U.S. Patent and Trademark Office.

By: P. Agris & S. Ashraf

Source: NC State University Libraries
Added: August 6, 2018

2005 patent

Methods and compositions for determining the purity of chemically synthesized nucleic acids

Washington, DC: U.S. Patent and Trademark Office.

By: P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Decoding the genome: A modified view

Nucleic Acids Research, 32(1), 223–238.

By: P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Modified nucleotides in tRNA(Lys) and tRNA(Val) are important for translocation

Journal of Molecular Biology, 338(3), 439–444.

By: S. Phelps, A. Malkiewicz, P. Agris & S. Joseph

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Sequence-altered peptide adopts optimum conformation for modification-dependent binding of the yeast tRNA(Phe) anticodon domain

Protein Journal, 23(1), 33–38.

By: P. Mucha, A. Szyk, P. Rekowski & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Structural characterization of an intermolecular RNA-RNA interaction involved in the transcription regulation element of a bipartite plant virus

Nucleic Acids Research, 32(9), 2819–2828.

By: R. Guenther, T. Sit, H. Gracz, M. Dolan, H. Townsend, G. Liu, W. Newman, P. Agris, S. Lommel

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

The role of modifications in codon discrimination by tRNA(Lys) UUU

Nature Structural & Molecular Biology, 11(12), 1186–1191.

By: F. Murphy, V. Ramakrishnan, A. Malkiewicz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Naturally-occurring modification restricts the anticodon domain conformational space of tRNA(Phe)

Journal of Molecular Biology, 334(5), 901–918.

By: J. Stuart, K. Koshlap, R. Guenther & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Using capillary electrophoresis to study methylation effect on RNA-peptide interaction

Acta Biochimica Polonica, 50(3), 857–864.

By: P. Mucha, A. Szyk, P. Rekowski & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Accurate translation of the genetic code depends on tRNA modified nucleosides

Journal of Biological Chemistry, 277(19), 16391–16395.

By: C. Yarian, H. Townsend, W. Czestkowski, E. Sochacka, A. Malkiewicz, R. Guenther, A. Miskiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Highly conserved modified nucleosides influence Mg2+-dependent tRNA folding

Nucleic Acids Research, 30(21), 4751–4760.

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Identification and quantification of protecting groups remaining in commercial oligonucleotide products using monoclonal antibodies

Analytical Biochemistry, 306(1), 135–143.

By: C. Fu, S. Smith, S. Simkins & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Interaction of RNA with phage display selected peptides analyzed by capillary electrophoresis mobility shift assay

RNA, 8(5), 698–704.

By: P. Mucha, A. Szyk, P. Rekowski, R. Guenther & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2002 personal communication

QC in antisense oligo synthesis

By: P. Agris, S. Smith, C. Fu & S. Simkins

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide

Biochemistry, 40(47), 14191–14199.

By: P. Mucha, A. Szyk, P. Rekowski, P. Weiss & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Functional anticodon architecture of human tRNA(Lys3) includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t(6)A

Biochemistry, 39(44), 13396–13404.

By: J. Stuart, Z. Gdaniec, R. Guenther, M. Marszalek, E. Sochacka, A. Malkiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Modified constructs of the tRNA TPsi C domain to probe substrate conformational requirements of m(1)A(58) and m(5)U(54) tRNA methyltransferases

Nucleic Acids Research, 28(6), 1374–1380.

By: R. Sengupta, S. Vainauskas, C. Yarian, E. Sochacka, A. Malkiewicz, R. Guenther, K. Koshlap, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Modified nucleoside dependent Watson-Crick and wobble codon binding by tRNA(UUU)(Lys) species

Biochemistry, 39(44), 13390–13395.

By: C. Yarian, M. Marszalek, E. Sochacka, A. Malkiewicz, R. Guenther, A. Miskiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Role of modified nucleosides of yeast tRNA(Phe) in ribosomal binding

Cell Biochemistry and Biophysics, 33(3), 241–252.

By: S. Ashraf, R. Guenther, G. Ansari, A. Malkiewicz, E. Sochacka & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Synthesis and properties of uniquely modified oligoribonucleotides: Yeast tRNA(Phe) fragments with 6-methyluridine and 5,6-dimethyluridine at site-specific positions

Nucleosides, Nucleotides & Nucleic Acids, 19(3), 515–531.

By: E. Sochacka, G. Czerwinska, R. Guenther, R. Cain, P. Agris & A. Malkiewicz

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

A distinctive RNA fold: The solution structure of an analogue of the yeast tRNA(Phe) T psi C domain

Biochemistry, 38(27), 8647–8656.

By: K. Koshlap, R. Guenther, E. Sochacka, A. Malkiewicz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1999 patent

Antibacterial agents and methods of screening for the same

Washington, DC: U.S. Patent and Trademark Office.

By: P. Agris & S. Ashraf

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Experimental models of protein-RNA interaction: Isolation and analyses of tRNA(Phe) and U1 snRNA-binding peptides from bacteriophage display libraries

Journal of Protein Chemistry, 18(4), 425–435.

By: P. Agris, M. Marchbank, W. Newman, R. Guenther, P. Ingram, J. Swallow, P. Mucha, A. Szyk ...

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Orientation of the tRNA anticodon in the ribosomal P-site: Quantitative footprinting with U-33-modified, anticodon stem and loop domains

RNA, 5(9), 1191–1199.

By: S. Ashraf, R. Guenther & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Single atom modification (O -> S) of tRNA confers ribosome binding

RNA, 5(2), 188–194.

By: S. Ashraf, E. Sochacka, R. Cain, R. Guenther, A. Malkiewicz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Structural and functional roles of the N1- and N3-protons of psi at tRNA's position 39

Nucleic Acids Research, 27(17), 3543–3549.

By: C. Yarian, M. Basti, R. Cain, G. Ansari, R. Guenther, E. Sochacka, G. Czerwinska, A. Malkiewicz, P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

The uridine in 'U-turn': Contributions to tRNA-ribosomal binding

RNA, 5(4), 503–511.

By: S. Ashraf, G. Ansari, R. Guenther, E. Sochacka, A. Malkiewicz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Thermodynamic contribution of nucleoside modifications to yeast tRNA(Phe) anticodon stem loop analogs

Acta Biochimica Polonica, 46(1), 163–172.

By: P. Agris, R. Guenther, E. Sochacka, W. Newman, G. Czerwinska, G. Liu, W. Ye, A. Malkiewicz

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Modified RNAs as potential drug targets

Acta Biochimica Polonica, 45(1), 13–18.

By: R. Guenther, B. Forrest, W. Newman, A. Malkiewicz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1997 conference paper

Ribosomal binding of modified tRNA anticodons related to thermal stability

Symposium on RNA Biology II. RNA: Tool and Target (1997: North Carolina Biotechnology Center) Research Triangle Park, North Carolina, USA, October 17-19, 1997 (Nucleic acids symposium series; no. 36), 36, 58–60. Oxford: Oxford University Press.

By: S. Ashraf, R. Guenther, W. Ye, Y. Lee, A. Malkiewicz & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Unconventional structure of tRNA(Lys)SUU anticodon explains tRNA's role in bacterial and mammalian ribosomal frameshifting and primer selection by HIV-1

RNA, 3(4), 420–428.

By: P. Agris, R. Guenther, P. Ingram, M. Basti, J. Stuart, E. Sochacka, A. Malkiewicz

Source: NC State University Libraries
Added: August 6, 2018