Adam Joseph Birkenheuer
Works (117)
Updated: October 30th, 2024 05:01
2024 article
ACVIM consensus statement on the diagnosis of immune thrombocytopenia in dogs and cats
LeVine, D. N., Kidd, L., Garden, O. A., Brooks, M. B., Goggs, R., Kohn, B., … Spada, E. (2024, May 16). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 5.
author keywords: autoimmune; hemostasis; immune-mediated; platelet; thrombopoietin
open access via onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 28, 2024
2024 journal article
Case report: Severe hepatopathy following rivaroxaban administration in a dog
FRONTIERS IN VETERINARY SCIENCE, 11.
author keywords: rivaroxaban; hepatopathy; canine; anticoagulant; factor Xa inhibitor
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 29, 2024
2024 article
Response to Correspondence on 'Analysis of US Marketed Artemisinin Supplements for Use in Dogs'
Berman, A. R., Birkenheuer, A. J., Sorah, E. L., & Papich, M. G. (2024, October 14). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 10.
Sources: Web Of Science, NC State University Libraries
Added: October 28, 2024
2023 journal article
A Novel Vaccine Strategy to Prevent Cytauxzoonosis in Domestic Cats
VACCINES, 11(3).
author keywords: cytauxzoonosis; Cytauxzoon felis; adenoviral vector vaccines; domestic cats; tick-borne diseases; c88; cf76
TL;DR:
A replication-defective human adenoviral vector (AdHu5) is used to deliver C. felis-specific immunogenic antigens and induce a cell-mediated and humoral immune response in cats and shows promising results as a vaccination strategy against cytauxzoonosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 17, 2023
2023 journal article
A practical protocol to prepare paraffin-embedded whole tick histology sections
TICKS AND TICK-BORNE DISEASES, 14(4).
MeSH headings : Animals; Humans; Fixatives; Paraffin Embedding; Ixodes; Tick-Borne Diseases
TL;DR:
A feasible protocol to prepare high quality paraffin-embedded whole tick histology sections is described that uses commonly available tools, reagents and standard histologic equipment and should allow any investigator to easily make adjustments to this protocol as needed based on their experimental goals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 24, 2023
2023 journal article
A retrospective study of vector borne disease prevalence among anemic dogs in North Carolina
PLOS ONE, 18(11).
TL;DR:
This study supported the use of PCR and serology run in parallel to maximize the chance of detecting exposure to or infection with VBD compared to either serology or PCR alone.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 18, 2024
2023 article
Gastric pH and serum gastrin concentration in age-matched healthy dogs and dogs with chronic kidney disease
Grady, K., Ernst, E., Secoura, P. L., Price, J., Birkenheuer, A., Vaden, S. L., … Tolbert, M. K. (2023, October 24). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 10.
author keywords: acid suppressant; azotemia; canine; famotidine; omeprazole
TL;DR:
The results suggest that prophylactic gastric acid suppression in dogs with CKD is not warranted unless other clinical indications for use are present.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 20, 2023
2023 journal article
Transmission of Cytauxzoon felis by injection of Amblyomma americanum salivary glands
PARASITOLOGY INTERNATIONAL, 95.
author keywords: Feline; Cytauxzoon felis; Sporozoite; Ticks; Salivary glands
MeSH headings : Animals; Cats; Amblyomma; Ixodidae / parasitology; Protozoan Infections, Animal / parasitology; Ticks / parasitology; Piroplasmida / physiology; Felis; Cat Diseases
TL;DR:
This study validates the feasibility of collecting infectious sporozoites from C. felis-infected ticks that can be used to infect naïve cats and has the potential to expand resources to study C.Felis and further advance research in this field.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 12, 2023
2022 journal article
A Serodiagnostic IgM ELISA to Detect Acute Cytauxzoonosis
PATHOGENS, 11(10).
author keywords: cytauxzoonosis; Cytauxzoon felis; domestic cats; diagnostic assay; ELISA; serology
TL;DR:
While further validation on assay performance is needed, the C. felis IgM ELISA is a promising test to detect acute cytauxzoonosis and can be utilized to develop a point-of-care test for clinical use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 7, 2022
2022 journal article
Babesia in North America An Update
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 52(6), 1193–1209.
author keywords: Babesia; Babesiosis; Canine; Tick-borne; Thrombocytopenia; Anemia
MeSH headings : Animals; Dogs; Babesia; Babesiosis / diagnosis; Babesiosis / pathology; Babesiosis / therapy; Dog Diseases / drug therapy; Dog Diseases / pathology; Dog Diseases / therapy; North America
TL;DR:
This updated article aims to provide practical guidance about the clinical manifestations of disease, treatment options, and outcomes of dog babesiosis, and the authors hope to provide some clarity about the taxonomy and nomenclature of these organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 12, 2022
2022 journal article
Cytauxzoon felis in salivary glands of Amblyomma americanum
TICKS AND TICK-BORNE DISEASES, 14(1).
author keywords: Cytauxzoon felis; Sporozoites; In situ hybridization; Tick; Salivary glands
MeSH headings : Cats; Animals; Amblyomma; Microscopy, Electron, Transmission; Salivary Glands
TL;DR:
The first direct visualization of any developing stage of C. felis within the tick host has been visualized microscopically, and it is believed that sporozoites in tick salivary glands (SG) have similar potential for cytauxzoonosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 13, 2023
2022 journal article
DETECTION OF VECTOR-BORNE INFECTIONS IN LIONS AND TIGERS AT TWO ZOOS IN TENNESSEE AND OKLAHOMA, USA
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 53(1), 50–59.
MeSH headings : Animals; Babesia / genetics; Lions; Oklahoma; Tennessee / epidemiology; Tigers
TL;DR:
The presence of tick-borne diseases in managed nondomestic felids in the southeastern United States is documents and underscores that ectoparasite control measures should be practiced to minimize exposure of carnivores in managed care.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 8, 2022
2022 journal article
Prevalence and genetic characterization of a Babesia microti-like species in the North American river otter (Lontra canadensis)
VETERINARY PARASITOLOGY- REGIONAL STUDIES AND REPORTS, 29.
author keywords: Babesiosis; Babesia microti -like species; Lontra canadensis; North American river otter; Hemolytic anemia; Phylogenetic analyses
MeSH headings : Animals; Babesia / genetics; Babesia microti / genetics; Babesiosis / parasitology; Dog Diseases / parasitology; Dogs; Foxes; Male; Otters / parasitology; Prevalence; RNA, Ribosomal, 18S / genetics; Raccoons / parasitology
TL;DR:
It is demonstrated that this piroplasm is a potential pathogen of North American river otters and the parasite is widespread in otter populations in the eastern United States.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022
2021 journal article
A novel missense mutation of the NAT10 gene in a juvenile Schnauzer dog with chronic respiratory tract infections
JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(3), 1542–1546.
author keywords: ciliary dysplasia; congenital; genetics; microtubule; pneumonia; whole genome sequencing
MeSH headings : Animals; Dog Diseases / genetics; Dogs; Male; Mutation; Mutation, Missense; Respiratory Tract Infections / genetics; Respiratory Tract Infections / veterinary; Whole Genome Sequencing / veterinary
TL;DR:
W Whole genome sequencing discovered a deleterious missense A/C mutation within the NAT10 gene, a gene essential for microtubule acetylation, appropriate ciliary development, and cytokinesis, suggesting a pathophysiological mechanism for this dog and highlighting an associated mutation or possible novel genetic cause of chronic respiratory infections in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 29, 2021
2021 journal article
Direct injection of Amblyomma americanum ticks with Cytauxzoon felis
TICKS AND TICK-BORNE DISEASES, 13(1).
author keywords: Cytauxzoon felis; Direct injection; Tick; In situ hybridization
MeSH headings : Amblyomma; Animals; Cat Diseases / epidemiology; Cats; Felis; Ixodidae / parasitology; Protozoan Infections, Animal / parasitology; Ticks
TL;DR:
The results suggest that injected C. felis remained alive in ticks but was unable to progress to infective sporozoites after injection, and the potential of using ticks as an alternative model to study C.Felis is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 23, 2021
2020 journal article
A new piroplasmid species infecting dogs: morphological and molecular characterization and pathogeny of Babesia negevi n. sp.
PARASITES & VECTORS, 13(1).
author keywords: Babesia negevi n; sp; Canine; Israel; Ornithodoros tholozani; Borrelia persica; Babesia duncani; Babesia conradae
MeSH headings : Animals; Babesia / classification; Babesia / cytology; Babesia / pathogenicity; Babesiosis / blood; Babesiosis / diagnosis; Babesiosis / parasitology; Borrelia / genetics; Borrelia / pathogenicity; Coinfection / microbiology; Coinfection / parasitology; Coinfection / veterinary; Cyclooxygenase 1 / genetics; Dog Diseases / blood; Dog Diseases / parasitology; Dogs; Female; Israel; Male; Phylogeny; RNA, Ribosomal, 18S / genetics; Sequence Analysis, DNA; Ticks / microbiology; Ticks / parasitology
TL;DR:
A new species of Babesia n.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 18, 2020
2020 journal article
Cytauxzoon felis cytochrome b gene mutation associated with atovaquone and azithromycin treatment
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(6), 2432–2437.
author keywords: anemia; apicomplexan; cytauxzoonosis; feline; mitochondrial; resistance
MeSH headings : Animals; Atovaquone / therapeutic use; Azithromycin / therapeutic use; Cat Diseases / drug therapy; Cats; Cytochromes b / genetics; Felis; Mutation; Protozoan Infections, Animal
TL;DR:
Parasites with mutations of cytb M128 can be selected and impart resistance to A&A treatment even with higher atovaquone dosing, according to this study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020
2020 journal article
Global distribution of canine Babesia species identified by a commercial diagnostic laboratory
VETERINARY PARASITOLOGY- REGIONAL STUDIES AND REPORTS, 22.
author keywords: Babesiosis; Canine; Ticks; Anemia; Thrombocytopenia; Azotemia; Proteinuria
MeSH headings : Animals; Babesia / classification; Babesiosis / diagnosis; Babesiosis / epidemiology; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs / parasitology; Laboratories; Polymerase Chain Reaction / veterinary
TL;DR:
This report characterize the results of over 100,000 canine samples from 52 different countries and territories spanning 4 continents that were submitted to a commercial diagnostic laboratory for Babesia testing by polymerase chain reaction to provide a global overview of which Babesian species veterinarians could expect to find in their practice area.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021
2020 journal article
Perceptions and attitudes of Small Animal Internal Medicine specialists toward the publication requirement for board certification
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 574–580.
author keywords: board certification; credentials; education; residency training
MeSH headings : Authorship; Certification; Humans; Societies, Scientific / organization & administration; Societies, Scientific / standards; Specialization; Specialty Boards / standards; Veterinary Medicine / organization & administration; Veterinary Medicine / standards
TL;DR:
A majority of SAIM Diplomates favored the retention of the publication requirement in some form, and publications submitted for credentialing purposes were cited at rates similar to control articles.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 17, 2020
2020 journal article
Second illness due to subsequent Cytauxzoon felis infection in a domestic cat
Journal of Feline Medicine and Surgery Open Reports.
author keywords: Cytauxzoonosis; schizont; piroplasm; vector-borne disease
TL;DR:
A castrated male domestic shorthair cat from a wooded area in Missouri had recovered from typical severe cytauxzoonosis at 4 years of age, after intensive in-hospital supportive care and administration of atovaquone and azithromycin and then developed a subsequent clinical illness typical of cytauxZoonosis, which was accompanied not only by intraerythrocytic piroplasms, but also by schizont-laden tissue macrophages pathognomonic of clinical cyt
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: August 6, 2020
2020 journal article
Serum procalcitonin concentrations in dogs with induced endotoxemia
Journal of Veterinary Internal Medicine, 1.
author keywords: animal model; biomarker; lipopolysaccharide; sepsis
MeSH headings : Animals; Cross-Over Studies; Dog Diseases / blood; Dog Diseases / chemically induced; Dogs; Endotoxemia / blood; Endotoxemia / chemically induced; Endotoxemia / veterinary; Lipopolysaccharides / toxicity; Male; Procalcitonin / blood
TL;DR:
Procalcitonin expression is likely to be a clinically useful biomarker for sepsis in dogs and might have an additional role in prognostication and therapeutic decision‐making.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: January 23, 2020
2020 journal article
Three‐dimensional bladder ultrasound for estimation of urine volume in dogs compared with traditional 2‐dimensional ultrasound methods
Journal of Veterinary Internal Medicine, 34(6), 2460–2467.
author keywords: bladder volume; dogs; ultrasound; urine
MeSH headings : Animals; Dogs; Point-of-Care Systems; Prospective Studies; Ultrasonography / veterinary; Urinary Bladder / diagnostic imaging
TL;DR:
The tested 3D ultrasound device was found to be an accurate and rapid point‐of‐care tool for measuring UBV in dogs, providing a noninvasive method to estimate bladder volume in real time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: November 24, 2020
2020 journal article
Validation of Bartonella henselae Western Immunoblotting for Serodiagnosis of Bartonelloses in Dogs
JOURNAL OF CLINICAL MICROBIOLOGY, 58(4).
author keywords: serology; zoonosis; vector borne; Western blotting; antigen; Bartonella henselae
MeSH headings : Animals; Antibodies, Bacterial; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae; Blotting, Western; Dog Diseases / diagnosis; Dogs; Serologic Tests
TL;DR:
This study characterized WB immunodominant proteins that could be used to confirm a serodiagnosis of canine bartonelloses using agar-grown Bartonella henselae San Antonio type 2 (SA2) whole-cell proteins, and found a strong but variable recognition of these proteins among 81% of group II dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 27, 2020
2019 journal article
ACVIM consensus statement on the diagnosis of immune-mediated hemolytic anemia in dogs and cats
JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(2), 313–334.
author keywords: comorbidity; Delphi survey; direct antiglobulin test; erythrocyte; evidence; flow cytometry; hemolysis; iceberg model; spherocyte; veterinary and comparative clinical immunology society
MeSH headings : Anemia, Hemolytic, Autoimmune / diagnosis; Anemia, Hemolytic, Autoimmune / etiology; Anemia, Hemolytic, Autoimmune / veterinary; Animals; Cat Diseases / diagnosis; Cat Diseases / etiology; Cats; Comorbidity; Consensus; Dog Diseases / diagnosis; Dog Diseases / etiology; Dogs; Societies, Veterinary
TL;DR:
Clinical guidelines for diagnosis of, and underlying disease screening for, IMHA in dogs and cats are provided, which should be implemented with consideration of animal, owner, and geographical factors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 22, 2019
2019 journal article
Babesia sp. infection in a zoo-housed polar bear (Ursus maritimus)
Veterinary Parasitology: Regional Studies and Reports.
author keywords: Babesiosis; Polar bear; Tick-borne disease; Wildlife
MeSH headings : Animals; Animals, Zoo; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / parasitology; Fatal Outcome; Female; New York; Ursidae
TL;DR:
A 28-year-old female polar bear housed in a zoo in Upstate New York presented with acute inappetence and lethargy, and because laboratory testing indicated severe hepatic and renal disease, the bear was humanely euthanized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: August 6, 2020
2019 journal article
Prevalence of Babesia spp. and clinical characteristics of Babesia vulpes infections in North American dogs
Journal of Veterinary Internal Medicine, 7.
author keywords: B; vulpes; Babesia; hemolytic anemia; prevalence; tick; vector-borne disease
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / transmission; Coinfection / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; North America / epidemiology; Polymerase Chain Reaction / veterinary; Prevalence
TL;DR:
The prevalence of Babesia sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 5, 2019
2018 journal article
Agreement between Parallel Canine Blood and Urine Cultures: Is Urine Culture the Poor Man's Blood Culture?
JOURNAL OF CLINICAL MICROBIOLOGY, 56(9).
Ed(s): B. Fenwick
author keywords: blood culture; bloodstream infections; concordance; dogs; urine culture
MeSH headings : Animals; Bacteremia / diagnosis; Bacteremia / veterinary; Bacteria / growth & development; Bacteria / isolation & purification; Bacteriological Techniques / veterinary; Blood Culture / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Retrospective Studies; Sensitivity and Specificity; Urinalysis / veterinary; Urinary Tract Infections / diagnosis; Urinary Tract Infections / veterinary
TL;DR:
It is found that urine culture is neither a substitute nor a screen for blood culture, and should be performed in any potentially septic animal, especially those that are considered immunosuppressed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 19, 2018
2018 journal article
Agreement between parallel canine blood and urine cultures: Is urine culture the poor man's blood culture?
Journal of Clinical Microbiology.
Source: ORCID
Added: August 6, 2020
2018 journal article
Azotemia and Proteinuria in Dogs Infected with Babesia gibsoni
Journal of the American Animal Hospital Association, 54(3), 156–160.
MeSH headings : Animals; Azotemia / diagnosis; Azotemia / veterinary; Babesia; Babesiosis / metabolism; DNA, Protozoan; Dog Diseases / diagnosis; Dog Diseases / metabolism; Dogs; Proteinuria / diagnosis; Proteinuria / veterinary; Retrospective Studies
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2018 journal article
Babesia gibsoni cytochrome b mutations in canine blood samples submitted to a US veterinary diagnostic laboratory
Journal of Veterinary Internal Medicine, 32(6), 1965–1969.
author keywords: atovaquone; mitochondrial; pharmacogenomics; resistance
MeSH headings : Animals; Babesia / genetics; Babesiosis / blood; Babesiosis / epidemiology; Babesiosis / parasitology; Cytochromes b / genetics; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Mutation / genetics; Pathology, Veterinary / statistics & numerical data; Prevalence; Real-Time Polymerase Chain Reaction / veterinary; United States / epidemiology
TL;DR:
The study reaffirms that B. gibsoni infection is widespread and most commonly detected in American Staffordshire Terrier/American Pit Bull Terrier dogs and that the prevalence of cytb mutations does not warrant pretreatment genotyping.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018
2018 journal article
Clinical, morphological, and molecular characterization of an undetermined Babesia species in a maned wolf (Chrysocyon brachyurus)
TICKS AND TICK-BORNE DISEASES, 10(1), 124–126.
author keywords: Babesia; Maned wolf; Chrysocyon brachyurus; PCR; Blood smear; Raccoon
MeSH headings : Animals; Animals, Zoo; Anti-Infective Agents / therapeutic use; Babesia / classification; Babesia / cytology; Babesia / genetics; Babesia / isolation & purification; Babesiosis / drug therapy; Babesiosis / microbiology; Canidae; Female; Treatment Outcome
TL;DR:
Clinical, morphological and molecular characterization of a possible novel Babesia species infection of a maned wolf with infection by an undetermined species suggested a unique Babesian species that is most closely related to a BabesIA species that has been found to infect raccoons in North America.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 28, 2019
2018 journal article
Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs
Journal of Veterinary Internal Medicine, 32(6), 1958–1964.
author keywords: bacteria; BAPGM; serology; vector-borne; zoonosis
MeSH headings : Animals; Antigens, Bacterial / immunology; Bartonella / immunology; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella quintana / immunology; Cells, Cultured; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique / methods; Fluorescent Antibody Technique / veterinary; Polymerase Chain Reaction / veterinary; Sensitivity and Specificity; Serologic Tests / methods; Serologic Tests / veterinary; Trench Fever / diagnosis; Trench Fever / veterinary
TL;DR:
Despite IFA testing of dogs against 8 different Bartonella isolates, IFA sensitivity remained poor, and specificity was only 85%.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018
2018 journal article
Genetic conservation of Cytauxzoon felis antigens and mRNA expression in the schizont life-stage
VETERINARY PARASITOLOGY, 263, 49–53.
author keywords: Feline; Cytauxzoon felis; Cytauxzoonosis; Antigen; Vaccine candidate; Genetic conservation
MeSH headings : Animals; Antigens, Protozoan / genetics; Cat Diseases / parasitology; Cats; DNA, Protozoan / genetics; Piroplasmida / genetics; Protozoan Infections, Animal / mortality; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / prevention & control; Protozoan Vaccines / genetics; Protozoan Vaccines / immunology; RNA, Messenger / genetics; Schizonts / genetics
TL;DR:
The suitability of three C. felis antigens for further investigation as vaccine candidates against cytauxzoonosis is assessed and robust levels of all transcripts in the schizont life stage of the parasite are revealed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 3, 2018
2018 journal article
Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis
CLINICAL PROTEOMICS, 15(1).
Contributors: M. Schreeg n, H. Marr n, J. Tarigo n, M. Sherrill*, H. Outi*, E. Scholl n, D. Bird n , A. Vigil*
author keywords: Cytauxzoonosis; Cytauxzoon felis; Expression library immunization; Protein microarray; Piroplasmid; Vaccine
TL;DR:
Protein microarray facilitated high-throughput identification of novel antigens, substantially increasing the pool of characterized C. felis Antigens and should be considered for development of C.Felis vaccines, diagnostics, and therapeutics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 14, 2019
2018 journal article
Molecular and Serological Prevalence of Anaplasma phagocytophilum, A. platys, Ehrlichia canis, E. chaffeenses, E. ewingii, Borrelia burgdorferi, Babesia canis, B. gibsoni and B. vogeli among Clinically Healthy Outdoor Dogs in Serbia
Veterinary Parasitology: Regional Studies and Reports, 14, 117–122.
author keywords: Molecular prevalence; seroprevalence; Tick-borne pathogens; Dogs; Serbia
MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasmosis / epidemiology; Animals; Animals, Wild; Antibodies, Bacterial / blood; Babesia / genetics; Borrelia burgdorferi / genetics; Disease Reservoirs / microbiology; Disease Reservoirs / parasitology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs / microbiology; Dogs / parasitology; Ehrlichia canis / genetics; Ehrlichiosis / veterinary; Female; Lyme Disease / veterinary; Male; Polymerase Chain Reaction; Prevalence; Serbia / epidemiology; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology
TL;DR:
It is concluded that outdoor dogs in this territory are reservoirs for B. canis and B. gibsoni and are frequently co-exposed to combinations of Anaplasma and Babesia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID, NC State University Libraries
Added: September 11, 2019
2017 journal article
Bartonella Seroepidemiology in Dogs from North America, 2008-2014
Journal of Veterinary Internal Medicine, 32(1), 222–231.
author keywords: Canine; Seroreactivity; Zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Male; North America / epidemiology; Seroepidemiologic Studies; Spatio-Temporal Analysis
TL;DR:
Male intact dogs, mixed breed dogs, and dogs exposed to other CVBD have higher seroreactivity to multiple Bartonella species, and geographic patterns supported broad distribution of exposure, and co‐exposure with otherCVBD was common.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Endothelial alterations in a canine model of immune thrombocytopenia
Platelets, 30(1), 88–97.
author keywords: Dog; endothelium; ITP
MeSH headings : Animals; Biomarkers; Biopsy; Blood Coagulation; Blood Platelets / metabolism; Blood Platelets / ultrastructure; Disease Models, Animal; Dogs; Endothelium / metabolism; Endothelium / ultrastructure; Flow Cytometry; Lysophospholipids / blood; Male; Platelet Activation; Platelet Count; Purpura, Thrombocytopenic, Idiopathic / blood; Purpura, Thrombocytopenic, Idiopathic / drug therapy; Purpura, Thrombocytopenic, Idiopathic / etiology; Purpura, Thrombocytopenic, Idiopathic / metabolism; Sphingosine / analogs & derivatives; Sphingosine / blood; von Willebrand Factor / metabolism
TL;DR:
The results indicate that endothelial damage occurs in the canine ITP model and variability in the degree of endothelialDamage may account for differences in the bleeding phenotype among patients with ITP.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: March 18, 2019
2017 journal article
Improved molecular detection of Babesia infections in animals using a novel quantitative real-time PCR diagnostic assay targeting mitochondrial DNA
Parasites & Vectors, 10(1).
author keywords: Canine babesiosis; Babesia; Mitochondrial DNA; Quantitative PCR
MeSH headings : Animals; Babesia / classification; Babesiosis / diagnosis; Babesiosis / parasitology; DNA, Mitochondrial / genetics; DNA, Protozoan / genetics; Real-Time Polymerase Chain Reaction / methods; Real-Time Polymerase Chain Reaction / veterinary
TL;DR:
A more sensitive qPCR assay with a more expansive range of Babesia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Molecular detection of vector-borne pathogens in Greek cats
TICKS AND TICK-BORNE DISEASES, 9(2), 171–175.
author keywords: Vector-borne pathogens; Bartonella spp.; Haemoplasmas; Cat; Greece
MeSH headings : Animals; Bacteria / isolation & purification; Bacterial Infections / epidemiology; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cat Diseases / parasitology; Cats; Greece / epidemiology; Piroplasmida / isolation & purification; Prevalence; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology
TL;DR:
This study represents the first description of Bartonella koehlerae in Greek cats, and there was no significant difference in either haemoplasma or Bart onella infection rates when comparing healthy and sick cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Intermittent At-Home Suctioning of Esophageal Content for Prevention of Recurrent Aspiration Pneumonia in 4 Dogs with Megaesophagus
JOURNAL OF VETERINARY INTERNAL MEDICINE, 30(5), 1715–1719.
author keywords: Esophagostomy; Regurgitation
MeSH headings : Animals; Catheters, Indwelling; Dog Diseases / etiology; Dog Diseases / prevention & control; Dogs; Enteral Nutrition; Esophageal Achalasia / complications; Esophageal Achalasia / veterinary; Female; Male; Pneumonia, Aspiration / etiology; Pneumonia, Aspiration / prevention & control; Pneumonia, Aspiration / veterinary; Recurrence; Suction / methods; Survival Analysis
TL;DR:
Use of intermittent esophageal suctioning in dogs with megaesophagus that continue to regurgitate despite gastrostomy tube feedings can reduce or abolish clinical episodes of aspiration pneumonia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Mitochondrial Genome Sequences and Structures Aid in the Resolution of Piroplasmida phylogeny
PLOS ONE, 11(11).
Contributors: M. Schreeg n, H. Marr n, J. Tarigo n, L. Cohn *, D. Bird n , E. Scholl n, M. Levy n, B. Wiegmann n , n
MeSH headings : DNA, Protozoan / genetics; Genome, Mitochondrial; Humans; Phylogeny; Piroplasmida / classification; Piroplasmida / genetics; Protozoan Infections / parasitology
TL;DR:
Phylogenetic analysis of concatenated mitochondrial and 18S sequences as well as cox1 amino acid sequence identified five distinct Piroplasmida groups, each of which possesses a unique mitochondrial genome structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
PCR amplification of a multi-copy mitochondrial gene (cox3) improves detection of Cytauxzoon felis infection as compared to a ribosomal gene (18S)
VETERINARY PARASITOLOGY, 225, 123–130.
Contributors: M. Schreeg n, H. Marr n, E. Griffith n , J. Tarigo n, D. Bird n , M. Reichard *, L. Cohn *, M. Levy n, n
author keywords: Cytauxzoonosis; Cytochrome c oxidase; Piroplasmosis; Mitochondria; Feline; Molecular diagnostic assays
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; DNA, Protozoan / blood; DNA, Protozoan / genetics; Electron Transport Complex IV / genetics; Gene Dosage; Haemosporida / genetics; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; RNA, Ribosomal, 18S / genetics; Sensitivity and Specificity
TL;DR:
A PCR assay targeting the C. felis mitochondrial gene cytochrome c oxidase subunit III (cox3) is designed and demonstrated that the cox3 PCR can detect as low as 1 copy of DNA target and can detect C.Felis during early infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Update on Canine and Feline Blood Donor Screening for Blood-Borne Pathogens
JOURNAL OF VETERINARY INTERNAL MEDICINE, 30(1), 15–35.
author keywords: Blood donor testing; Transfusions
MeSH headings : Animals; Blood Donors; Blood Transfusion / veterinary; Blood-Borne Pathogens / isolation & purification; Cat Diseases / blood; Cat Diseases / prevention & control; Cats; Communicable Diseases / transmission; Communicable Diseases / veterinary; Disease Transmission, Infectious / veterinary; Dog Diseases / blood; Dog Diseases / prevention & control; Dogs
TL;DR:
An update on the 2005 American College of Veterinary Internal Medicine Consensus Statement on blood donor infectious disease screening was presented at the 2015 ACVIM Forum in Indianapolis, Indiana, and is presented below.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Coagulation abnormalities in 5 cats with naturally occurring cytauxzoonosis
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 25(4), 538–545.
author keywords: disseminated intravascular coagulation; feline; sepsis; thromboelastography
MeSH headings : Animals; Blood Cell Count / veterinary; Blood Coagulation Tests / veterinary; Cat Diseases / blood; Cats; Cross-Sectional Studies; Disseminated Intravascular Coagulation / blood; Disseminated Intravascular Coagulation / veterinary; Female; Fibrinogen; Hemostasis; Male; Piroplasmida; Prothrombin Time / veterinary; Protozoan Infections / blood; Sepsis / blood; Sepsis / veterinary; Thrombelastography / veterinary
TL;DR:
This is the first report that comprehensively describes the hemostastic status of cats with naturally occurring infection with Cytauxzoon felis and all 5 cats had laboratory evidence of overt DIC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Prevalence of Cytauxzoon felis infection in healthy cats from enzootic areas in Arkansas, Missouri, and Oklahoma
PARASITES & VECTORS, 8.
author keywords: Arkansas; Cats; Cytauxzoon felis; Missouri; Oklahoma
MeSH headings : Animals; Arachnid Vectors / parasitology; Arkansas / epidemiology; Cat Diseases / epidemiology; Cat Diseases / parasitology; Cats; Ixodidae / parasitology; Missouri / epidemiology; Oklahoma / epidemiology; Piroplasmida / physiology; Prevalence; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology
TL;DR:
The high prevalence of C. felis in healthy domestic cats from Arkansas, Missouri, and Oklahoma suggests that infected domestic cats are likely reservoirs of infection for naive felines and substantiates the importance for the use of approved acaricides on cats to prevent cytauxzoonosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Rapid High-Resolution Melt Analysis of Cytauxzoon felis Cytochrome b To Aid in the Prognosis of Cytauxzoonosis
JOURNAL OF CLINICAL MICROBIOLOGY, 53(8), 2517–2524.
MeSH headings : Alleles; Animals; Antiprotozoal Agents / therapeutic use; Atovaquone / therapeutic use; Azithromycin / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Cytochromes b / genetics; Genotype; Genotyping Techniques / methods; Piroplasmida / drug effects; Piroplasmida / genetics; Piroplasmida / isolation & purification; Polymerase Chain Reaction / methods; Prognosis; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Protozoan Proteins / genetics; Sensitivity and Specificity; Transition Temperature; Veterinary Medicine / methods
TL;DR:
The purpose of this study was to design a PCR panel that could distinguish C. felis cytb1 from other cytochrome b genotypes, and this panel was predicted to distinguish cytb 1 from other cytb genotypes through the use of high-resolution melt analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs?
British Journal of Haematology, 167(1), 110–120.
author keywords: immune thrombocytopenia; canine; interleukin-8; animal model
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Monoclonal / adverse effects; Antibodies, Monoclonal / immunology; Blood Platelets / immunology; Blood Platelets / metabolism; Cytokines / blood; Cytokines / metabolism; Disease Models, Animal; Dogs; Hemorrhage / immunology; Phenotype; Platelet Count; Purpura, Thrombocytopenic, Idiopathic / blood; Purpura, Thrombocytopenic, Idiopathic / diagnosis; Purpura, Thrombocytopenic, Idiopathic / immunology
TL;DR:
Evaluation of cytokine profiles led to the identification of platelets as a potential source of serum interleukin‐8 (IL8) in dogs, suggesting that platelet IL8 may be a previously unrecognized modulator of platelet‐neutrophil crosstalk in humans with ITP.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Comparison of serological and molecular panels for diagnosis of vector-borne diseases in dogs
Parasites & Vectors, 7(1), 127.
author keywords: Canine vector-borne diseases; Serology; Molecular testing; Diagnostic panel
MeSH headings : Animals; Bacterial Infections / blood; Bacterial Infections / diagnosis; Bacterial Infections / microbiology; Bacterial Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Parasitic Diseases, Animal / blood; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / parasitology; Serologic Tests / veterinary
TL;DR:
Serological and PCR assays should be used in parallel to maximize CVBD diagnosis, and a panel combining serological and molecular assays run in parallel resulted in a 4-58% increase in the recognition of exposure to or infection with CVBD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID, NC State University Libraries, Web Of Science
Added: August 6, 2018
2014 journal article
Copperhead (Agkistrodon contortrix) envenomation of dogs: 52 cases (2004-2011)
Journal of the American Animal Hospital Association.
MeSH headings : Agkistrodon; Animals; Antivenins / administration & dosage; Crotalid Venoms; Dog Diseases / epidemiology; Dog Diseases / therapy; Dogs; Emergency Medical Services; Female; Male; Snake Bites / epidemiology; Snake Bites / veterinary; United States / epidemiology
TL;DR:
It is found that the clinical course after copperhead envenomation is generally limited to local rather than systemic illness and is largely self-limiting and responsive to supportive care with hospitalization for monitoring.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 6, 2020
2014 journal article
Identification of Parabodo caudatus (class Kinetoplastea) in urine voided from a dog with hematuria
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 27(1), 117–120.
author keywords: Bodo urinarius; canine; flagellate; Parabodo caudatus; protozoa
MeSH headings : Animals; DNA, Protozoan / genetics; Dog Diseases / parasitology; Dog Diseases / urine; Dogs; Euglenozoa Infections / parasitology; Euglenozoa Infections / urine; Euglenozoa Infections / veterinary; Hematuria / parasitology; Hematuria / urine; Hematuria / veterinary; Kinetoplastida / genetics; Kinetoplastida / isolation & purification; Male; Polymerase Chain Reaction / veterinary; RNA, Ribosomal, 18S / genetics
TL;DR:
A voided urine sample was observed to contain biflagellate protozoa 5 days following an episode of gross hematuria, and Parabodo caudatus organisms were unable to be demonstrated cytologically or by means of PCR in samples collected from the dog’s environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
Investigation of a Commercial ELISA for the Detection of Canine Procalcitonin
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(2), 599–602.
author keywords: Sepsis; Diagnostic test; Dog; Validation; Biomarker
MeSH headings : Animals; Biomarkers / blood; Calcitonin / blood; Dog Diseases / blood; Dogs / blood; Enzyme-Linked Immunosorbent Assay / veterinary; Protein Precursors / blood; Reproducibility of Results; Sepsis / blood; Sepsis / veterinary; Thyroid Neoplasms / blood; Thyroid Neoplasms / veterinary
TL;DR:
The results of this investigation do not support the use of this ELISA for the detection of Procalcitonin (PCT) in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae
Journal of Clinical Microbiology, 52(9), 3447–3452.
Ed(s): E. Munson
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Diarrhea / microbiology; Diarrhea / pathology; Diarrhea / veterinary; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Flea Infestations / complications; Flea Infestations / veterinary; Male; Prostatitis / diagnosis; Prostatitis / microbiology; Prostatitis / pathology; Steatitis / microbiology; Steatitis / pathology
TL;DR:
A dog developed an unusual clinical presentation for canine bartonellosis following an acute flea infestation, and comprehensive medical, microbiological, and surgical interventions were required for diagnosis and to achieve a full recovery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Regional Seroreactivity and Vector-Borne Disease Co-Exposures in Dogs in the United States from 2004–2010: Utility of Canine Surveillance
Vector-Borne and Zoonotic Diseases, 14(10), 724–732.
author keywords: Dirofilaria; Rickettsia; Babesia; Ehrlichia; United States; Anaplasma; Borrelia; Bartonella; Surveillance
MeSH headings : Anaplasma / immunology; Anaplasmosis / epidemiology; Animals; Arachnid Vectors / microbiology; Arachnid Vectors / parasitology; Babesia / immunology; Babesiosis / epidemiology; Bartonella / immunology; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Borrelia burgdorferi / immunology; Coinfection / veterinary; Dirofilaria immitis / immunology; Dirofilariasis / epidemiology; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Ehrlichia / immunology; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Lyme Disease / epidemiology; Retrospective Studies; Rickettsia / immunology; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary; Ticks / microbiology; Ticks / parasitology; United States / epidemiology
TL;DR:
Notable annual and regional seroreactivity variation was observed with certain pathogens over 7 years of study, suggesting canine surveillance studies may have value in contributing to future VBD knowledge.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
A Novel Candidate Vaccine for Cytauxzoonosis Inferred from Comparative Apicomplexan Genomics
PLOS ONE, 8(8).
Contributors: J. Tarigo n, E. Scholl n, D. Bird n, C. Brown *, L. Cohn *, G. Dean n, M. Levy n, D. Doolan *
MeSH headings : Animals; Antigens, Protozoan / genetics; Antigens, Protozoan / immunology; Cat Diseases / immunology; Cat Diseases / parasitology; Cat Diseases / prevention & control; Cats; Cattle; Conserved Sequence; Genome, Protozoan; Genomics; Immune Sera / immunology; Piroplasmida / genetics; Piroplasmida / immunology; Protozoan Infections, Animal / immunology; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / prevention & control; Protozoan Proteins / genetics; Protozoan Proteins / immunology; Protozoan Vaccines / genetics; Protozoan Vaccines / immunology; Recombinant Proteins / genetics; Recombinant Proteins / immunology; Synteny; Theileria parva / genetics; Theileria parva / immunology
TL;DR:
Comparative genomics is used to computationally and experimentally interpret the C. felis genome to identify a novel candidate vaccine antigen for cytauxzoonosis, and this approach emphasizes the use of comparative genomics as an accelerated path to developing vaccines against experimentally intractable pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Failure of efficacy and adverse events associated with dose-intense diminazene diaceturate treatment of chronic Cytauxzoon felis infection in five cats
JOURNAL OF FELINE MEDICINE AND SURGERY, 16(2), 157–163.
MeSH headings : Animals; Antiprotozoal Agents / administration & dosage; Antiprotozoal Agents / adverse effects; Antiprotozoal Agents / therapeutic use; Carrier State; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Chronic Disease; Diminazene / administration & dosage; Diminazene / adverse effects; Diminazene / analogs & derivatives; Diminazene / therapeutic use; Dose-Response Relationship, Drug; Female; Male; Parasitic Diseases, Animal / drug therapy; Treatment Failure
TL;DR:
It is hypothesized that a dose-intensified regimen of diminazene could reduce or eliminate parasitemia from five domestic cats naturally infected with C felis and that Diminazene diaceturate cannot be recommended for elimination of the carrier state of C fel is infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Infection with Panola MountainEhrlichiasp. in a Dog with Atypical Lymphocytes and Clonal T-Cell Expansion
Journal of Veterinary Internal Medicine, 27(5), 1251–1255.
author keywords: Lymphocytosis; Panola Mountain Ehrlichia sp.; Clonal T-cell expansion; Bacteria; Tick vector
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dog Diseases / microbiology; Dogs; Doxycycline / therapeutic use; Ehrlichia / classification; Ehrlichiosis / blood; Ehrlichiosis / drug therapy; Ehrlichiosis / veterinary; Liver / cytology; Lymph Nodes / cytology; Lymphocytosis / veterinary; Male; T-Lymphocytes / classification; T-Lymphocytes / cytology; T-Lymphocytes / physiology; Thrombocytopenia / veterinary
TL;DR:
An 11-year-old, castrated male Scottish Terrier that lived predominantly indoors and had no travel history was referred to the North Carolina State University Veterinary Health Complex in October 2012 for routine reevaluation of hepatobiliary disease and morphologic abnormalities raised the suspicion of possible lymphoid neoplasia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
Pharmacogenomics of Cytauxzoon felis Cytochrome b: Implications for Atovaquone and Azithromycin Therapy in Domestic Cats with Cytauxzoonosis
JOURNAL OF CLINICAL MICROBIOLOGY, 51(9), 3066–3069.
MeSH headings : Animals; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / therapeutic use; Atovaquone / pharmacokinetics; Atovaquone / therapeutic use; Azithromycin / pharmacokinetics; Azithromycin / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Cytochromes b / genetics; Cytochromes b / metabolism; Pharmacogenetics; Piroplasmida / genetics; Piroplasmida / metabolism; Protozoan Infections / drug therapy; Protozoan Infections / parasitology
TL;DR:
This work characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonosis and found a cytb genotype that was associated with survival in A&A-treated cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Splenosystemic Shunts in Cats: A Retrospective of 33 Cases (2004-2011)
JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1347–1353.
author keywords: Acquired; Congenital; Hepatic; Portal hypertension; Ultrasound
MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Cohort Studies; Female; Hypertension, Portal / veterinary; Male; Renal Veins / diagnostic imaging; Renal Veins / pathology; Retrospective Studies; Splenic Vein / diagnostic imaging; Splenic Vein / pathology; Ultrasonography; Vena Cava, Inferior / diagnostic imaging; Vena Cava, Inferior / pathology
TL;DR:
Neither the signalment of cats in this report nor the anatomy of their portovascular anomalies shared similarities with those cats previously identified with single-vessel shunts, so the relevance and etiology of these newly described splenosystemic shunts remain elusive and warrants further investigation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
A Myristoylated Alanine-Rich C Kinase Substrate–Related Peptide Suppresses Cytokine mRNA and Protein Expression in LPS-Activated Canine Neutrophils
American Journal of Respiratory Cell and Molecular Biology, 48(3), 314–321.
author keywords: MARCKS; cytokine; inflammation; neutrophil
MeSH headings : Animals; Dogs; Humans; Interleukin-8 / biosynthesis; Interleukin-8 / genetics; Interleukin-8 / metabolism; Intracellular Signaling Peptides and Proteins / metabolism; Lipopolysaccharides / pharmacology; Membrane Proteins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Neutrophils / drug effects; Neutrophils / metabolism; Peptides / metabolism; Peptides / pharmacology; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Tumor Necrosis Factor-alpha / biosynthesis; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism
TL;DR:
Observations identify MARCKS protein as a promising therapeutic target in the treatment of inflammatory diseases or syndromes attributed to neutrophil influx and inflammatory cytokine production, such as sepsis, acute lung injury, and acute respiratory distress syndrome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2012 journal article
Congenital Adrenal Hyperplasia Associated with Mutation in an 11 ss-Hydroxylase-Like Gene in a Cat
JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(5), 1221–1226.
author keywords: Androgen; Feline; Hermaphrodite; Hypertension
MeSH headings : Adrenal Hyperplasia, Congenital / enzymology; Adrenal Hyperplasia, Congenital / genetics; Adrenal Hyperplasia, Congenital / veterinary; Animals; Cat Diseases / enzymology; Cat Diseases / genetics; Cats; DNA / chemistry; DNA / genetics; Male; Point Mutation; Polymerase Chain Reaction / veterinary; Sequence Analysis, DNA; Steroid 11-beta-Hydroxylase / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Diminazene Diaceturate for Treatment of Chronic Cytauxzoon felis Parasitemia in Naturally Infected Cats
Journal of Veterinary Internal Medicine.
author keywords: Cytauxzoonosis; Piroplasm; Antiprotozoal; Carrier
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Carrier State; Cat Diseases / drug therapy; Cats; Diminazene / analogs & derivatives; Diminazene / therapeutic use; Parasitemia / drug therapy; Parasitemia / veterinary; Parasitic Diseases, Animal / drug therapy; Real-Time Polymerase Chain Reaction / veterinary
TL;DR:
Dinazene diaceturate was unable to eliminate the pathogen or decrease parasite burden in healthy, chronically infected cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: August 6, 2020
2012 journal article
Evaluation of Cytauxzoon felis infection status in captive-born wild felids housed in an area endemic for the pathogen
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 241(8), 1088–1092.
MeSH headings : Animals; Apicomplexa / classification; Apicomplexa / isolation & purification; Arkansas / epidemiology; Cats; Disease Reservoirs / veterinary; Endemic Diseases / veterinary; Felidae; Female; Male; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology
TL;DR:
Whether apparently healthy captive-born wild felids that were not native to North America and were housed in an area endemic for Cytauxzoon felis harbored the pathogen is investigated to determine whether apparently healthy captives without clinical signs of disease tested positive for C felis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Hypocalcemia and Hypovitaminosis D in Dogs with Induced Endotoxemia
JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(2), 244–251.
author keywords: Animal model; Calcium; Magnesium; Parathyroid hormone; Sepsis; Vitamin D
MeSH headings : Animals; Blood Gas Analysis / veterinary; Blood Pressure; Body Temperature; Calcium / blood; Calcium / urine; Cross-Over Studies; Dog Diseases / blood; Dog Diseases / metabolism; Dogs; Endotoxemia / blood; Endotoxemia / complications; Endotoxemia / metabolism; Endotoxemia / veterinary; Hypocalcemia / blood; Hypocalcemia / complications; Hypocalcemia / metabolism; Hypocalcemia / veterinary; Magnesium / blood; Magnesium / urine; Male; Parathyroid Hormone / blood; Vitamin D / analogs & derivatives; Vitamin D / blood
TL;DR:
Hypocalcemia occurs during endotoxemia in dogs and is associated with hypovitaminosis D, and hypomagnesemia, hypoparathyroidism, alkalosis, and increased calciuresis are not associated with HypocalCEmia in endotoxemic dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Lack of evidence for perinatal transmission of Cytauxzoon felis in domestic cats
VETERINARY PARASITOLOGY, 188(1-2), 172–174.
author keywords: Hemoprotozoa; Apicomplexa; Theileriidae; Vertical transmission
MeSH headings : Animals; Carrier State; Cat Diseases / epidemiology; Cat Diseases / parasitology; Cat Diseases / transmission; Cats; Female; Infectious Disease Transmission, Vertical / veterinary; Male; Missouri / epidemiology; Piroplasmida / classification; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / transmission
TL;DR:
This work investigated the possibility of perinatal transmission of C. felis from chronically infected cats to their offspring and found that two queens produced a total of 14 healthy kittens in three litters.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Pathology in practice. Intraerythrocytic infection with organisms consistent with a large Babesia sp.
Journal of the American Veterinary Medical Association, 241(8), 1029–1031.
MeSH headings : Animals; Babesia / cytology; Babesia / isolation & purification; Babesiosis / microbiology; Babesiosis / pathology; Babesiosis / veterinary; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; Male
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Re-emergence of Babesia conradae and effective treatment of infected dogs with atovaquone and azithromycin
VETERINARY PARASITOLOGY, 187(1-2), 23–27.
author keywords: Protozoal; Babesiosis; Piroplasm; Babesia gibsoni
MeSH headings : Animals; Antiprotozoal Agents / administration & dosage; Antiprotozoal Agents / therapeutic use; Atovaquone / administration & dosage; Atovaquone / therapeutic use; Azithromycin / administration & dosage; Azithromycin / therapeutic use; Babesia / classification; Babesiosis / drug therapy; Babesiosis / epidemiology; Babesiosis / parasitology; Babesiosis / veterinary; California / epidemiology; Communicable Diseases, Emerging / epidemiology; Communicable Diseases, Emerging / parasitology; Communicable Diseases, Emerging / veterinary; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dog Diseases / genetics; Dog Diseases / parasitology; Dogs; Female; Male; Pedigree
TL;DR:
Combination therapy with atovaquone and azithromycin appears to be effective for acute and chronic babesiosis caused by B. conradae.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Variation in the ITS-1 and ITS-2 rRNA genomic regions of Cytauxzoon felis from bobcats and pumas in the eastern United States and comparison with sequences from domestic cats
Veterinary Parasitology, 190(1-2), 29–35.
author keywords: Bobcat; Cytauxzoon; rRNA; Internal transcribed spacer unit; Genetic variability; Florida puma
MeSH headings : Animals; Appalachian Region / epidemiology; Base Sequence; Cat Diseases / epidemiology; Cat Diseases / parasitology; Cats; DNA, Protozoan / analysis; DNA, Protozoan / genetics; DNA, Ribosomal Spacer / analysis; DNA, Ribosomal Spacer / genetics; Disease Reservoirs; Genetic Variation / genetics; Genotype; Lynx / parasitology; Midwestern United States / epidemiology; Molecular Sequence Data; Piroplasmida / genetics; Piroplasmida / isolation & purification; Prevalence; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology; Puma / parasitology; Sequence Analysis, DNA; Southeastern United States / epidemiology; Species Specificity
TL;DR:
Investigation of intraspecific variation of the C. felis internal transcribed spacer (ITS)-1 and ITS-2 rRNA regions from 145 wild felids in the United States indicates that, based on ITS-1 andITS-2 sequences, numerous C.Felis strains may circulate inWild felids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 6, 2020
2011 journal article
Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils
Developmental & Comparative Immunology, 35(8), 872–880.
author keywords: TREM-1; TLR; Neutrophils; Sepsis; Canine
MeSH headings : Amino Acid Sequence; Animals; Cells, Cultured; Cloning, Molecular; Conserved Sequence; Cytokines / immunology; Cytokines / metabolism; Dogs / genetics; Dogs / immunology; Humans; Lipopolysaccharides / immunology; Lipopolysaccharides / pharmacology; Membrane Glycoproteins / genetics; Membrane Glycoproteins / immunology; Membrane Glycoproteins / metabolism; Molecular Sequence Data; Neutrophils / immunology; Neutrophils / metabolism; Phylogeny; Receptors, Immunologic / genetics; Receptors, Immunologic / metabolism; Sequence Alignment; Teichoic Acids / immunology; Teichoic Acids / pharmacology; Toll-Like Receptors / agonists; Up-Regulation / drug effects
TL;DR:
Functionally, canine TREM-1 synergistically enhances LPS-induced production of IL-8, TNF-α and a canine orthologue of CXCL1 and these data suggest that T REM-1 expression in dogs is an amplifier of pro-inflammatory responses to microbial products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Pharmacokinetics of diminazene diaceturate in healthy cats
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(6), 608–610.
MeSH headings : Animals; Antiprotozoal Agents / blood; Antiprotozoal Agents / pharmacokinetics; Area Under Curve; Cats / blood; Chromatography, High Pressure Liquid; Diminazene / analogs & derivatives; Diminazene / blood; Diminazene / pharmacokinetics; Female; Half-Life; Male
TL;DR:
The pharmacokinetic profile of diminazene diaceturate in cats was characterized and it was found that this drug, if found to be effective for the treatment of C. felis, would offer advantages both in practicality of dosing and in cost.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Prevalence of infectious diseases in cats and dogs rescued following Hurricane Katrina
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 238(3), 311–317.
MeSH headings : Animals; Cat Diseases / epidemiology; Cat Diseases / transmission; Cats; Communicable Diseases / epidemiology; Communicable Diseases / transmission; Communicable Diseases / veterinary; Cyclonic Storms; Disasters; Dog Diseases / epidemiology; Dog Diseases / transmission; Dogs; Female; Male; Prevalence; United States / epidemiology
TL;DR:
The dispersal of potentially infectious animals to other regions of North America where some infections were not typically found could have contributed to new geographic ranges for these organisms or to underdiagnosis in affected animals because of a low index of suspicion in regions with low disease prevalence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Babesia (Theileria) annae in a Red Fox (Vulpes vulpes) from Prince Edward Island, Canada
Journal of Wildlife Diseases, 46(2), 615–621.
author keywords: Babesia (Theileria) annae; Canada; Prince Edward Island; red fox; Vulpes vulpes
MeSH headings : Animals; DNA, Protozoan / analysis; Fatal Outcome; Female; Foxes / parasitology; Prince Edward Island / epidemiology; Theileria / isolation & purification; Theileriasis / epidemiology
TL;DR:
This is the first reported case of a red fox in Canada infected with a piroplasm and it remains uncertain whether the presence of this hemoparasite in this fox was pathogenic or an incidental finding.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2010 journal article
Babesia canis and Babesia rossi co-infection in an untraveled Nigerian dog
VETERINARY PARASITOLOGY, 173(3-4), 334–335.
author keywords: Babesia; Canine; Africa
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Babesia / genetics; Babesia / isolation & purification; Babesiosis / drug therapy; Babesiosis / parasitology; Babesiosis / veterinary; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; Diminazene / analogs & derivatives; Diminazene / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Female; Nigeria; Polymerase Chain Reaction / veterinary; Sequence Analysis, DNA
TL;DR:
This study constitutes the first report of co-infection with B. canis and B. rossi in the West African sub-region and the first reported of autochthonous B.Canis on the African continent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Babesia microti-like infections are prevalent in North American foxes
VETERINARY PARASITOLOGY, 172(3-4), 179–182.
author keywords: Babesia; Tick; Anemia; Azotemia; Piroplasmosis
MeSH headings : Animals; Babesia microti / genetics; Babesiosis / epidemiology; Babesiosis / parasitology; Coyotes / parasitology; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Foxes / parasitology; Molecular Sequence Data; North America; Prevalence; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology; RNA, Ribosomal, 18S / genetics; Spain; Tubulin / genetics
TL;DR:
Interestingly, partial beta-tubulin gene sequences characterized from the B. microti-like parasites of domestic dogs from Spain in this study were different from those previously reported from a Spanish domestic dog sample which is believed to be a pseudogene.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Efficacy of Atovaquone and Azithromycin or Imidocarb Dipropionate in Cats with Acute Cytauxzoonosis
JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(1), 55–60.
author keywords: Antimicrobials; Clinical Trials; Microbiology; Molecular biology; Parasitology; PCR assays; Protozoa
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Atovaquone / therapeutic use; Azithromycin / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; Drug Therapy, Combination / veterinary; Female; Genotype; Imidocarb / analogs & derivatives; Imidocarb / therapeutic use; Logistic Models; Male; Parasitemia / drug therapy; Parasitemia / parasitology; Parasitemia / veterinary; Piroplasmida / genetics; Piroplasmida / isolation & purification; Polymerase Chain Reaction / veterinary; Prospective Studies; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Survival Analysis
TL;DR:
Survival to discharge was more likely in cats treated with A&A as compared with imidocarb, although case fatality rate remained high, and cats with a lower parasitemia were more likely to survive.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Evaluation of Brain Tissue or Cerebrospinal Fluid with Broadly Reactive Polymerase Chain Reaction for Ehrlichia, Anaplasma, Spotted Fever Group Rickettsia, Bartonella, and Borrelia Species in Canine Neurological Diseases (109 Cases)
Journal of Veterinary Internal Medicine, 24(2), 372–378.
author keywords: Central nervous system (CNS); Inflammation; Meningoencephalomyelitis; Vector-borne microorganisms
MeSH headings : Animals; Brain / microbiology; DNA, Bacterial / classification; DNA, Bacterial / isolation & purification; Dog Diseases / cerebrospinal fluid; Dog Diseases / microbiology; Dogs; Female; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacterial Infections / cerebrospinal fluid; Gram-Negative Bacterial Infections / microbiology; Gram-Negative Bacterial Infections / veterinary; Male; Meningoencephalitis / microbiology; Meningoencephalitis / veterinary; Polymerase Chain Reaction / veterinary
TL;DR:
The results of this investigation suggest that microorganisms in the genera Ehrlichia, Anaplasma, Rickettsia, Bartonella, and Borrelia are unlikely to be directly associated with canine MEM in the geographic regions evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2010 journal article
Prevalence of Selected Vector-borne Organisms and Identification of Bartonella Species DNA in North American River Otters (Lontra canadensis)
Journal of Wildlife Diseases, 46(3), 947–950.
author keywords: Bartonella; disease; Ehrlichia; Lontra canadensis; Ricketisia; river otter
MeSH headings : Animals; Animals, Wild / microbiology; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; DNA, Bacterial / blood; Female; Male; North Carolina / epidemiology; Otters / virology; Polymerase Chain Reaction / veterinary; Prevalence; Rivers
TL;DR:
Trapper-killed North American river otters in North Carolina, USA, were screened for multiple vector-borne bacteria known to be pathogenic to mammals and blood from one live otter captured in 2008 was found positive for this Bartonella sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2010 journal article
Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam
MEDICAL MYCOLOGY, 49(5), 539–542.
author keywords: pythiosis; dogs; terbinafine; itraconazole; mefenoxam
MeSH headings : Alanine / administration & dosage; Alanine / adverse effects; Alanine / analogs & derivatives; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / adverse effects; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Duodenum / pathology; Female; Gastrointestinal Diseases / diagnosis; Gastrointestinal Diseases / drug therapy; Gastrointestinal Diseases / pathology; Gastrointestinal Diseases / veterinary; Histocytochemistry; Itraconazole / administration & dosage; Itraconazole / adverse effects; Naphthalenes / administration & dosage; Naphthalenes / adverse effects; Pythiosis / diagnosis; Pythiosis / drug therapy; Pythiosis / pathology; Pythiosis / veterinary; Pythium / isolation & purification; Terbinafine; Treatment Outcome
TL;DR:
A case of canine gastrointestinal pythiosis in which lesions were resolved through the administration of itraconazole, terbinafine, and the agricultural fungicide mefenoxam is described.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Babesiosis Caused by a Large Babesia Species in 7 Immunocompromised Dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(1), 127–131.
author keywords: Anemia; Chemotherapy; Splenectomy; Thrombocytopenia
MeSH headings : Animals; Babesia / classification; Babesia / genetics; Babesiosis / parasitology; Babesiosis / veterinary; DNA, Protozoan / genetics; Dog Diseases / immunology; Dog Diseases / parasitology; Dogs; Immunocompromised Host; RNA, Ribosomal, 18S / genetics; Retrospective Studies
TL;DR:
Dogs with pigmenturia, anemia, and thrombocytopenia should be tested for Babesia sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
DIAGNOSIS AND TREATMENT OF BABESIA ODOCOILEI IN CAPTIVE REINDEER (RANGIFER TARANDUS TARANDUS) AND RECOGNITION OF THREE NOVEL HOST SPECIES
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 40(1), 152–159.
author keywords: Anemia; Babesia; hemolysis; imidocarb dipropionate; Rangifer tarandus tarandus; reindeer
MeSH headings : Animals; Animals, Zoo; Antiprotozoal Agents / therapeutic use; Arachnid Vectors / parasitology; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / drug therapy; Babesiosis / transmission; Babesiosis / veterinary; Female; Imidocarb / therapeutic use; Male; RNA, Ribosomal, 18S / chemistry; RNA, Ribosomal, 18S / genetics; Reindeer / parasitology; Sequence Analysis, RNA; Species Specificity; Ticks / parasitology; Treatment Outcome
TL;DR:
Due to the high morbidity and mortality associated with acute babesiosis, captive reindeer should receive tick prevention, be tested for subclinical infections in endemic areas, and receive aggressive treatment for acute infections when clinical Babesiosis is suspected.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets in a Pomeranian Dog Caused by a Novel Mutation in the Vitamin D Receptor Gene
JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(6), 1278–1283.
MeSH headings : Animals; Dog Diseases / drug therapy; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genetic Predisposition to Disease; Hypocalcemia / veterinary; Receptors, Calcitriol / genetics; Rickets / drug therapy; Rickets / genetics; Rickets / veterinary; Vitamin D / analogs & derivatives; Vitamin D / pharmacology
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
Bartonella DNA in the Blood and Lymph Nodes of Golden Retrievers with Lymphoma and in Healthy Controls
Journal of Veterinary Internal Medicine, 22(1), 89–95.
author keywords: bacteria; cancer; dog; tick; vector-borne
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / veterinary; Case-Control Studies; DNA, Bacterial / analysis; DNA, Bacterial / blood; Disease Vectors; Dog Diseases / blood; Dog Diseases / microbiology; Dogs; Female; Lymph Nodes / microbiology; Lymphoma / microbiology; Lymphoma / veterinary; Male; Models, Statistical; Polymerase Chain Reaction / veterinary; Risk Factors; Surveys and Questionnaires
TL;DR:
Bartonella DNA can be detected in blood and lymph nodes; importantly, in this report, Bartonella was detected in the same proportion of clinically healthy dogs and dogs with lymphoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2008 journal article
Cytauxzoon felis infections are present in bobcats (Lynx rufus) in a region where cytauxzoonosis is not recognized in domestic cats
VETERINARY PARASITOLOGY, 153(1-2), 126–130.
author keywords: cytauxzoonosis; piroplasmosis; Cytauxzoon felis; bobcats; PCR; tick
MeSH headings : Animals; Cat Diseases / epidemiology; Cat Diseases / parasitology; Cats; Eukaryota / classification; Eukaryota / isolation & purification; Lynx / parasitology; North Carolina / epidemiology; Pennsylvania / epidemiology; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology
TL;DR:
This study indicates the potential for C. felis infections in domestic cats in the northeastern USA if the appropriate tick vectors are present and Veterinary practitioners in PA should be on alert for cytauxzoonosis in domestic Cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
Evaluation of four DNA extraction methods for the detection of Tritrichomonas foetus in feline stool specimens by polymerase chain reaction
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 20(5), 639–641.
author keywords: Cats; feces; polymerase chain reaction; protozoa
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / economics; Cat Diseases / parasitology; Cats; Costs and Cost Analysis; DNA, Protozoan / genetics; DNA, Protozoan / isolation & purification; Feces / parasitology; North Carolina; Polymerase Chain Reaction / methods; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 16S / isolation & purification; Trichomonas / genetics; Trichomonas Infections / diagnosis; Trichomonas Infections / economics; Trichomonas Infections / veterinary
TL;DR:
In the present study, 4 commercially available DNA extraction methods were examined for their influence on the sensitivity of PCR for the detection of Tritrichomonas foetus in feline stool and the ZR Fecal DNA kit was identified as affording the greatest analytical sensitivity and reproducibility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
Failure to identify an association between serologic or molecular evidence ofBartonellainfection and idiopathic rhinitis in dogs
Journal of the American Veterinary Medical Association, 233(4), 597–599.
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Case-Control Studies; DNA, Bacterial / analysis; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Rhinitis / diagnosis; Rhinitis / microbiology; Rhinitis / veterinary
TL;DR:
The failure to find any evidence of exposure to or infection with Bartonella spp in dogs with idiopathic nasal discharge suggested that Bart onella infection was not a common cause of the disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2008 journal article
Use of a nitinol gooseneck snare catheter for removal of adult Dirofilaria immitis in two cats
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 233(9), 1441–1445.
MeSH headings : Animals; Cardiac Catheterization / instrumentation; Cardiac Catheterization / methods; Cardiac Catheterization / veterinary; Cat Diseases / parasitology; Cat Diseases / surgery; Cats; Chylothorax / etiology; Chylothorax / parasitology; Chylothorax / surgery; Chylothorax / veterinary; Dirofilaria immitis / isolation & purification; Dirofilariasis / complications; Dirofilariasis / surgery; Female; Heart Failure / surgery; Heart Failure / veterinary; Male; Treatment Outcome
TL;DR:
Findings suggested that use of a nitinol gooseneck snare catheter may be a safe and effective technique for removing adult D immitis from the right atrium and ventricle in cats and that successful removal of adult heartworms in infected cats may resolve clinical signs of right-sided congestive heart failure and chylothorax.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Antibiotic-resistant Corynebacterium jeikeium urinary tract infection in a cat
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 43(1), 61–64.
MeSH headings : Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Bacteriuria / microbiology; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Corynebacterium / drug effects; Corynebacterium / genetics; Corynebacterium / isolation & purification; Corynebacterium Infections / drug therapy; Corynebacterium Infections / microbiology; Corynebacterium Infections / veterinary; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors / administration & dosage; Enzyme Inhibitors / pharmacology; Male; Microbial Sensitivity Tests / veterinary; RNA, Ribosomal, 16S / genetics; Treatment Outcome; Urinary Tract Infections / drug therapy; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR:
Urine culture and gene sequencing identified Corynebacterium jeikeium, which was resistant to antibiotics and appeared to be the cause of the urinary tract infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Bartonella DNA in Loggerhead Sea Turtles
Emerging Infectious Diseases, 13(6), 949–950.
MeSH headings : Animals; Atlantic Ocean; Bartonella / genetics; Bartonella / isolation & purification; Bartonella / pathogenicity; Bartonella Infections / blood; Bartonella Infections / genetics; Bartonella Infections / veterinary; DNA, Bacterial / classification; North Carolina; Polymerase Chain Reaction; Turtles / blood; Turtles / microbiology
TL;DR:
Pathogenic bacteria are an important threat in terrestrial and marine environments, and in the case of B. henselae, reservoir hosts may be more diverse than currently recognized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2007 journal article
In vitro cultivation of a newly recognized Babesia sp in dogs in North Carolina
VETERINARY PARASITOLOGY, 151(2-4), 150–157.
author keywords: Babesia sp.; canine babesiosis; HL-1 medium; microaerophilous stationary phase culture; RPMI-1640; small subunit ribosomal RNA gene; transmission electron microscopy
MeSH headings : Animals; Babesia / classification; Babesia / genetics; Babesia / growth & development; Babesia / ultrastructure; Babesiosis / parasitology; Babesiosis / veterinary; Base Sequence; Cells, Cultured; Dog Diseases / parasitology; Dogs; Female; Genes, rRNA / genetics; Microscopy, Electron, Transmission / veterinary; Molecular Sequence Data; North Carolina; Species Specificity
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Molecular evidence of prevalent dual piroplasma infections in North American raccoons (Procyon lotor)
PARASITOLOGY, 135(1), 33–37.
author keywords: Babesia; piroplasmosis; babesiosis
MeSH headings : Animals; Babesia / genetics; Babesia / isolation & purification; Babesia microti / genetics; Babesia microti / isolation & purification; Babesiosis / parasitology; Babesiosis / veterinary; DNA Primers / chemistry; DNA, Protozoan / analysis; DNA, Protozoan / blood; Genotype; North Carolina; Parasitic Diseases, Animal / parasitology; Polymerase Chain Reaction / veterinary; RNA, Ribosomal, 18S / genetics; Raccoons / parasitology; Sequence Homology, Nucleic Acid
TL;DR:
This study highlights the need for molecular assays for the accurate identification of piroplasma and performs a molecular survey of raccoons using polymerase chain reaction assays specific for each genotype.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Quantification of mucin gene expression in tracheobronchial epithelium of healthy dogs and dogs with chronic bronchitis
AMERICAN JOURNAL OF VETERINARY RESEARCH, 68(4), 435–440.
MeSH headings : Animals; Bronchitis, Chronic / metabolism; Bronchitis, Chronic / veterinary; DNA Primers; Dog Diseases / metabolism; Dogs; Evaluation Studies as Topic; Mucins / metabolism; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; RNA, Messenger / metabolism
TL;DR:
The ability to measure mucin gene expression from tracheobronchial brushing specimens collected from client-owned dogs during routine bronchoscopy should prove to be a useful tool for the study of bronchitis in dogs and expand the usefulness of airway inflammation in dogs as a model for bronchritis in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
The detection of Cytauxzoon felis in apparently healthy free-roaming cats in the USA
VETERINARY PARASITOLOGY, 146(3-4), 316–320.
author keywords: Cytauxzoonosis; PCR; free-roaming; survival; hyperendemic
MeSH headings : Animals; Carrier State; Cat Diseases / epidemiology; Cat Diseases / parasitology; Cats; Female; Male; Piroplasmida; Protozoan Infections, Animal / epidemiology; Protozoan Infections, Animal / parasitology; United States / epidemiology
TL;DR:
Despite the low prevalence rate, the presence of apparently healthy infected free-roaming cats suggests that they may have the capacity to serve as an additional reservoir host for C. felis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 article
Use of basal serum or plasma cortisol concentrations to rule out a diagnosis of hypoadrenocorticism in dogs: 123 cases (2000-2005)
Lennon, E. M., Boyle, T. E., Hutchins, R. G., Friedenthal, A., Correa, M. T., Bissett, S. A., … Birkenheuer, A. J. (2007, August 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 231, pp. 413–416.
MeSH headings : Adrenal Glands / pathology; Adrenal Insufficiency / blood; Adrenal Insufficiency / diagnosis; Adrenal Insufficiency / genetics; Adrenal Insufficiency / veterinary; Animals; Case-Control Studies; Diagnosis, Differential; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / genetics; Dogs; Female; Genetic Predisposition to Disease; Hydrocortisone / blood; Male; Nova Scotia / epidemiology; Pedigree; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
Cytauxzoon felisinfection in cats in the mid-Atlantic states: 34 cases (1998–2004)
Journal of the American Veterinary Medical Association, 228(4), 568–571.
MeSH headings : Animals; Base Sequence; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cats; Diagnosis, Differential; Female; Geography; Male; North Carolina / epidemiology; Piroplasmida / isolation & purification; Piroplasmida / pathogenicity; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / epidemiology; RNA, Protozoan / genetics; RNA, Ribosomal / genetics; RNA, Ribosomal, 18S / genetics; Retrospective Studies; Seasons; Sequence Homology, Nucleic Acid; South Carolina / epidemiology; Virginia / epidemiology
TL;DR:
Data indicate that veterinarians in the mid-Atlantic region of the United States should consider C. felis infection in cats that become ill with fever, icterus, and pancytopenia or bicy topenia, especially in the spring and summer months.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2006 journal article
Development and evaluation of a PCR assay for the detection of Cytauxzoon felis DNA in feline blood samples
VETERINARY PARASITOLOGY, 137(1-2), 144–149.
author keywords: cytauxzoonosis; piroplasmosis; pancytopenia
MeSH headings : Animals; Blood / parasitology; Cat Diseases / blood; Cat Diseases / diagnosis; Cat Diseases / mortality; Cat Diseases / parasitology; Cats; DNA, Protozoan / analysis; Ixodidae / parasitology; Piroplasmida / genetics; Piroplasmida / isolation & purification; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / blood; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / mortality; Protozoan Infections, Animal / parasitology; RNA, Ribosomal, 18S / analysis; Sensitivity and Specificity
TL;DR:
This work has developed and evaluated the sensitivity and specificity of a polymerase chain reaction (PCR) based assay and can be used for the rapid clinical diagnosis of cytauxzoonosis and for epidemiological studies that will better define the geographic distribution of C. felis infection in cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 article
Efficacy of ronidazole for treatment of feline Tritrichomonas foetus infection
JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 20, pp. 536–543.
author keywords: colitis; diarrhea; metronidazole; nitroimidazole; tinidazole
TL;DR:
Oral administration of RDZ at 30 to 50 mg/kg PO q12h for 14 days resolved diarrhea and eradicated infection in 1 naturally infected cat and 10 experimentally inoculated cats receiving a different isolate of T foetus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
Molecular characterization of a Babesia species identified in a North American raccoon
JOURNAL OF WILDLIFE DISEASES, 42(2), 375–380.
Contributors: n , J. Whittington*, J. Neel n , E. Large n, A. Barger*, M. Levy n, E. Breitschwerdt n
author keywords: Babesia; PCR; phylogenetics; piroplasm; Procyon lotor; raccoon; taxonomy
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / parasitology; Babesiosis / transmission; Babesiosis / veterinary; Diagnosis, Differential; Disease Reservoirs / veterinary; Gene Amplification; Humans; Male; Phylogeny; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; RNA, Protozoan / analysis; RNA, Ribosomal, 18S / analysis; Raccoons / parasitology; Zoonoses
TL;DR:
The data generated in this study can be used to design molecular diagnostic tests for detection of this Babesia sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
The identification of a genetically unique piroplasma in North American river otters (Lontra canadensis)
PARASITOLOGY, 134(5), 631–635.
author keywords: Babesia; North American river otter; PCR; phylogenetics
MeSH headings : Animals; Babesia / genetics; Babesia / isolation & purification; Base Sequence; Molecular Sequence Data; North America; Otters / parasitology; Phylogeny; RNA, Protozoan / genetics; RNA, Ribosomal, 18S / genetics; Rivers
TL;DR:
It is indicated that the prevalence of piroplasma in North Carolina otters is quite high and the pathogenic potential of this organism for otters or other species remains unknown.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Canine and feline blood donor screening for infectious disease
JOURNAL OF VETERINARY INTERNAL MEDICINE, 19(1), 135–142.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Geographic distribution of babesiosis among dogs in the United States and association with dog bites: 150 cases (2000-2003)
Journal of the American Veterinary Medical Association, 227(6), 942–947.
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / transmission; Babesiosis / veterinary; Bites and Stings / complications; Bites and Stings / veterinary; Breeding; DNA, Protozoan / analysis; Dog Diseases / epidemiology; Dog Diseases / transmission; Dogs; Geography; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Retrospective Studies; United States / epidemiology
TL;DR:
Testing for babesiosis should be pursued in dogs with clinicopathologic abnormalities consistent with immune-mediated hemolytic anemia or thrombocytopenia, particularly if there is a history of a recent dog bite.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2005 journal article
Icterus and pancytopenia in a cat
NAVC Clinician's Brief, 3(7), 21.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Molecular characterization of trichomonads from feces of dogs with diarrhea
JOURNAL OF PARASITOLOGY, 91(4), 939–943.
MeSH headings : Animals; Base Sequence; DNA, Protozoan / chemistry; DNA, Protozoan / isolation & purification; Diarrhea / parasitology; Diarrhea / veterinary; Dog Diseases / parasitology; Dogs; Electrophoresis, Agar Gel / veterinary; Feces / parasitology; Female; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Protozoan Infections / parasitology; Protozoan Infections, Animal; RNA, Ribosomal / genetics; Sequence Alignment / veterinary; Trichomonadida / classification; Trichomonadida / genetics; Trichomonadida / isolation & purification; Tritrichomonas foetus / classification; Tritrichomonas foetus / genetics; Tritrichomonas foetus / isolation & purification
TL;DR:
The present study is the first to establish the molecular identity of trichomonads infecting dogs with diarrhea, and validate the longstanding assumption that canine trICHomoniasis may be attributed to P. hominis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
Detection and molecular characterization of a novel large Babesia species in a dog
Veterinary Parasitology, 124(3-4), 151–160.
Contributors: n , J. Neel n , D. Ruslander n, M. Levy n & E. Breitschwerdt n
author keywords: piroplasm; babesiosis; 18S; rRNA; taxonomy
MeSH headings : Animals; Antibodies, Protozoan / blood; Antiprotozoal Agents / therapeutic use; Babesia / classification; Babesia / genetics; Babesia / immunology; Babesia / isolation & purification; Babesiosis / drug therapy; Babesiosis / parasitology; Babesiosis / veterinary; Cross Reactions; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Imidocarb / therapeutic use; Phylogeny; Polymerase Chain Reaction / veterinary; RNA, Ribosomal, 18S; Sequence Homology, Nucleic Acid; Treatment Outcome
TL;DR:
The molecular characterization of a large Babesia species that was detected in the blood and bone marrow of a dog with clinical and hematological abnormalities consistent with babesiosis is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2004 journal article
Efficacy of Combined Atovaquone and Azithromycin for Therapy of Chronic Babesia gibsoni (Asian Genotype) Infections in Dogs
Journal of Veterinary Internal Medicine.
TL;DR:
A combination of atovaquone and azithromycin is the 1st described treatment that will either eliminate B. gibsoni (Asian genotype) infections or suppress the parasitemia below the limit of detection in the majority of treated dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 6, 2020
2004 article
Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 18, pp. 494–498.
author keywords: piroplasm; polymerase chain reaction; protozoa; treatment
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
Concurrent bartonellosis and babesiosis in a dog with persistent thrombocytopenia
Journal of the American Veterinary Medical Association, 223(9), 1306–1310.
MeSH headings : Animals; Antibodies, Protozoan / blood; Antiprotozoal Agents / therapeutic use; Babesia / genetics; Babesia / immunology; Babesia / isolation & purification; Babesiosis / complications; Babesiosis / diagnosis; Babesiosis / veterinary; Bartonella Infections / complications; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; DNA, Protozoan / blood; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / etiology; Dogs; Imidocarb / analogs & derivatives; Imidocarb / therapeutic use; Male; Polymerase Chain Reaction / veterinary; Thrombocytopenia / etiology; Thrombocytopenia / veterinary
TL;DR:
Polymerase chain reaction (PCR) analysis of multiple stored blood samples obtained during the 5-month period of persistent thrombocytopenia identified DNA of B. canis vogeli.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2003 journal article
Development and Evaluation of a Seminested PCR for Detection and Differentiation of Babesia gibsoni (Asian Genotype) and B. canis DNA in Canine Blood Samples
Journal of Clinical Microbiology, 41(9), 4172–4177.
MeSH headings : Animals; Babesia / genetics; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / veterinary; DNA, Protozoan / blood; Dog Diseases / diagnosis; Dogs; Polymerase Chain Reaction / methods; RNA, Ribosomal, 18S / chemistry; RNA, Ribosomal, 18S / genetics; Sensitivity and Specificity
TL;DR:
The seminested PCR test was able to detect and discriminate B. gibsoni (Asian genotype), B.Canis subsp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2003 journal article
Serosurvey of antiBabesia antibodies in stray dogs and American pit bull terriers and American Staffordshire terriers from North Carolina
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(6), 551–557.
MeSH headings : Animals; Antibodies, Protozoan / blood; Babesia / immunology; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / veterinary; DNA, Protozoan / analysis; Dog Diseases / epidemiology; Dogs; Female; Male; North Carolina / epidemiology; Seroepidemiologic Studies
TL;DR:
There was no association between antiBabesia antibodies and the presence of ticks, and there are currently Babesia gibsoni epizootics affecting American pit bull terrier kennels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2003 journal article
Transfusion-associated Babesia gibsoni infection in a dog
Journal of the American Veterinary Medical Association, 222(7), 959–963.
MeSH headings : Animals; Antibodies, Protozoan / analysis; Antiprotozoal Agents / therapeutic use; Babesia / immunology; Babesiosis / diagnosis; Babesiosis / drug therapy; Babesiosis / etiology; Babesiosis / veterinary; Blood Transfusion / veterinary; Carrier State / diagnosis; Carrier State / parasitology; Carrier State / veterinary; DNA, Protozoan / isolation & purification; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / etiology; Dogs; Female; Fluorescent Antibody Technique / veterinary; Hematocrit / veterinary; Hysterectomy / veterinary; Ovariectomy / veterinary; Polymerase Chain Reaction / veterinary; Splenomegaly / parasitology; Splenomegaly / veterinary; Transfusion Reaction; Treatment Outcome
TL;DR:
A series of antiparasitic treatments failed to eliminate the B gibsoni infection and screening of potential blood donor dogs for Babesia spp is becoming increasingly important in the United States.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2003 journal article
Tritrichomonas foetus and not Pentatrichomonas hominis is the etiologic agent of feline trichomonal diarrhea
JOURNAL OF PARASITOLOGY, 89(1), 99–104.
TL;DR:
The purpose of the present study was to determine the identity of this recently recognized flagellate by means of rRNA gene sequence analysis; restriction enzyme digest mapping; and light, transmission, and scanning electron microscopy (SEM).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Differentiation of Haemobartonella canis and Mycoplasma haemofelis on the basis of comparative analysis of gene sequences
American Journal of Veterinary Research, 63(10), 1385–1388.
MeSH headings : Anaplasmataceae / classification; Anaplasmataceae / genetics; Anaplasmataceae Infections / microbiology; Anaplasmataceae Infections / veterinary; Animals; Base Sequence; Cat Diseases / microbiology; Cats; DNA, Ribosomal / genetics; Dog Diseases / microbiology; Dogs; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Phylogeny; Ribonucleases / genetics; Species Specificity
TL;DR:
Haemobartonella canis and M haemofelis are not identical organisms and molecular differentiation is more clearly evident by use of comparative analysis of RNase P gene sequences than by comparativeAnalysis of 16S rDNA gene sequences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2002 journal article
Retrospective study of proliferative papillary vulvitis in Florida panthers
JOURNAL OF WILDLIFE DISEASES, 38(1), 115–123.
author keywords: Florida panther; cougar; Pumas concolor coryi; proliferative vulvitis; vestibulum vaginae; pathology; reproduction
MeSH headings : Animals; Animals, Wild; Carnivora; Epithelium / pathology; Female; Florida; Immunohistochemistry / veterinary; Microscopy, Electron / veterinary; Prevalence; Retrospective Studies; Vagina / pathology; Vagina / ultrastructure; Vulvitis / diagnosis; Vulvitis / epidemiology; Vulvitis / veterinary
TL;DR:
Proliferative, papillary vulvitis was identified in 16 of 34 free-ranging and captive female Florida panthers monitored over a period from 1983–98 and did not appear to have a significant effect on reproduction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Single-Tube Nested PCR for Detection of Tritrichomonasfoetus in Feline Feces
Journal of Clinical Microbiology, 40(11), 4126–4130.
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / parasitology; Cats; DNA Primers; DNA, Protozoan / analysis; DNA, Ribosomal / analysis; Feces / parasitology; Polymerase Chain Reaction / instrumentation; Polymerase Chain Reaction / methods; Protozoan Infections / diagnosis; Protozoan Infections / parasitology; Protozoan Infections, Animal; RNA, Ribosomal, 5.8S / genetics; Sensitivity and Specificity; Tritrichomonas foetus / genetics; Tritrichomonas foetus / isolation & purification
TL;DR:
The results demonstrate that the single-tube nested PCR is ideally suited for diagnostic testing of feline fecal samples that are found negative by direct microscopy and culturing and definitive identification of microscopically observable or cultivated organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2002 journal article
Visceral leishmaniasis in a New York foxhound kennel
JOURNAL OF VETERINARY INTERNAL MEDICINE, 16(1), 34–44.
author keywords: canine; dogs; Leishmania; sand fly
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Visceral leishmaniasis in a New York foxhound kennel
Journal of Veterinary Internal Medicine.
TL;DR:
Foxhounds that were > 18 months of age or that had traveled to the southeastern United States were more likely to be diagnosed with visceral leishmaniasis and transmission of Leishmania spp.
(via Semantic Scholar)
Source: ORCID
Added: August 6, 2020
2001 journal article
Canine Rocky Mountain spotted fever: A retrospective study of 30 cases
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 37(1), 41–48.
MeSH headings : Animals; Antibodies, Bacterial / blood; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dogs; Female; Male; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Rickettsia rickettsii / immunology; Rocky Mountain Spotted Fever / epidemiology; Rocky Mountain Spotted Fever / veterinary
TL;DR:
Dogs with antibody titers of 1:1,024 or greater at the time of presentation had a higher incidence of more severe neurological dysfunction and cutaneous lesions and the survival rate following R. rickettsii infection was 100%.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2000 journal article
There are at least three genetically distinct small piroplasms from dogs
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 30(14), 1501–1505.
author keywords: Babesia gibsoni; Babesia canis; 18S rRNA phylogeny; piroplasms; anaemia; protozoa; tick-transmitted; tick vector
MeSH headings : Alabama; Animals; Babesia / classification; Babesia / genetics; Databases, Factual; Dogs / parasitology; Indiana; Japan; Missouri; Molecular Sequence Data; North Carolina; Oklahoma; Phylogeny; RNA, Ribosomal, 18S / genetics; Theileria / genetics
TL;DR:
The 18S nuclear subunit ribosomal RNA (18S rRNA) gene of small piroplasms isolated from dogs from Okinawa (Japan), Oklahoma, North Carolina, Indiana, Missouri, and Alabama, was isolated and sequenced and suggested that there are multiple small piraplasm species in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
1999 journal article
Babesia gibsoni infections in dogs from North Carolina
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 35(2), 125–128.
MeSH headings : Animals; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / epidemiology; Babesiosis / therapy; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Male; North Carolina / epidemiology
TL;DR:
The recognition of canine babesiosis in North Carolina caused by Babesia gibsoni documents the expansion of the previously reported endemic area of this disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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