Works (31)

2022 journal article

DINOS: Data INspired Oligo Synthesis for DNA Data Storage

ACM JOURNAL ON EMERGING TECHNOLOGIES IN COMPUTING SYSTEMS, 18(3).

By: K. Volkel, K. Tomek, A. Keung & J. Tuck

author keywords: DNA information storage; DNA synthesis; DNA assembly algorithms
Sources: Web Of Science, ORCID
Added: April 14, 2022

2022 journal article

Human Pluripotent Stem Cell-Derived Medium Spiny Neuron-like Cells Exhibit Gene Desensitization

CELLS, 11(9).

By: R. Tam & A. Keung

author keywords: dopamine; gene desensitization; acute and chronic; RNA-seq; human embryonic stem cell; medium spiny neuron
Source: Web Of Science
Added: May 23, 2022

2022 journal article

Modified Histone Peptides Linked to Magnetic Beads Reduce Binding Specificity

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(3).

By: J. Meanor, A. Keung & B. Rao

author keywords: yeast surface display; histone post-translational modifications; affinity reagents; protein engineering; chromodomain; binder; reader; antibody; epigenome engineering; synthetic biology
Source: Web Of Science
Added: February 21, 2022

2021 review

DNA stability: a central design consideration for DNA data storage systems

[Review of ]. NATURE COMMUNICATIONS, 12(1).

By: K. Matange, J. Tuck & A. Keung

Sources: Web Of Science, ORCID
Added: April 19, 2021

2021 journal article

Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids

BMC BIOTECHNOLOGY, 21(1).

By: D. Sen, A. Voulgaropoulos & A. Keung

author keywords: Human cerebral organoids; Neurodevelopment; Agarose microwells; Microfabrication; RNAseq; Mechanobiology
Source: Web Of Science
Added: October 26, 2021

2021 journal article

Evaluation of UBE3A antibodies in mice and human cerebral organoids

SCIENTIFIC REPORTS, 11(1).

By: D. Sen, Z. Drobna & A. Keung

Source: Web Of Science
Added: July 19, 2021

2021 journal article

Mapping the dynamic transfer functions of eukaryotic gene regulation

CELL SYSTEMS, 12(11), 1079-+.

By: J. Lee, L. Caywood, J. Lo n, N. Levering n & A. Keung

Sources: Web Of Science, ORCID
Added: January 31, 2022

2021 journal article

Mapping the residue specificities of epigenome enzymes by yeast surface display

CELL CHEMICAL BIOLOGY, 28(12), 1772-+.

By: A. Waldman, B. Rao & A. Keung

Source: Web Of Science
Added: January 3, 2022

2021 journal article

Promiscuous molecules for smarter file operations in DNA-based data storage

NATURE COMMUNICATIONS, 12(1).

By: K. Tomek, K. Volkel, E. Indermaur n, J. Tuck & A. Keung

Sources: Web Of Science, ORCID
Added: July 12, 2021

2021 article

Voices of biotech research

Annabi, N., Baker, M., Boettiger, A., Chakraborty, D., Chen, Y., Corbett, K. S., … Wang, J. (2021, March). NATURE BIOTECHNOLOGY, Vol. 39, pp. 281–286.

Source: Web Of Science
Added: April 5, 2021

2020 review

Capturing complex epigenetic phenomena through human multicellular systems

[Review of ]. CURRENT OPINION IN BIOMEDICAL ENGINEERING, 16, 34–41.

By: D. Sen & A. Keung

author keywords: Epigenetics; Organoids; Development; Aging; 3D; Multicellular
Source: Web Of Science
Added: June 10, 2021

2020 journal article

Dynamic and scalable DNA-based information storage

NATURE COMMUNICATIONS, 11(1).

By: K. Lin, K. Volkel, J. Tuck & A. Keung

Sources: Web Of Science, ORCID
Added: July 13, 2020

2020 journal article

Human Cerebral Organoids Reveal Early Spatiotemporal Dynamics and Pharmacological Responses of UBE3A

STEM CELL REPORTS, 15(4), 845–854.

Source: Web Of Science
Added: November 9, 2020

2019 journal article

Driving the Scalability of DNA-Based Information Storage Systems

ACS SYNTHETIC BIOLOGY, 8(6), 1241–1248.

By: K. Tomek, K. Volkel n, A. Simpson n, A. Hass n, E. Indermaur n, J. Tuck, A. Keung

author keywords: synthetic biology; DNA storage; information storage; nested architecture; file access; DNA sequencing
Source: Web Of Science
Added: July 15, 2019

2019 journal article

Engineering Epigenetic Regulation Using Synthetic Read-Write Modules

CELL, 176(1-2), 227-+.

By: M. Park*, N. Patel*, A. Keung & A. Khalil*

Source: Web Of Science
Added: January 28, 2019

2019 journal article

Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis

NATURE COMMUNICATIONS, 10.

By: C. Liao n, F. Ttofali, R. Slotkowski, S. Denny, T. Cecil n, R. Leenay, A. Keung, C. Beisel

Source: Web Of Science
Added: July 22, 2019

2016 article

A unifying model of epigenetic regulation

Keung, A. J., & Khalil, A. S. (2016, February 12). SCIENCE, Vol. 351, pp. 661–662.

By: A. Keung & A. Khalil*

Source: Web Of Science
Added: August 6, 2018

2016 review

The epigenome: the next substrate for engineering

[Review of ]. GENOME BIOLOGY, 17.

By: M. Park*, A. Keung & A. Khalil*

Source: Web Of Science
Added: August 6, 2018

2015 journal article

Chromatin regulation at the frontier of synthetic biology

Nature Reviews Genetics, 16(3), 159–171.

Source: Crossref
Added: February 24, 2020

2014 journal article

Using Targeted Chromatin Regulators to Engineer Combinatorial and Spatial Transcriptional Regulation

Cell, 158(1), 110–120.

Source: Crossref
Added: August 28, 2020

2013 journal article

Pan-neuronal maturation but not neuronal subtype differentiation of adult neural stem cells is mechanosensitive

Scientific Reports, 3(1).

By: A. Keung, M. Dong*, D. Schaffer* & S. Kumar*

Source: Crossref
Added: August 28, 2020

2012 journal article

A Genetic Strategy for the Dynamic and Graded Control of Cell Mechanics, Motility, and Matrix Remodeling

Biophysical Journal, 102(3), 434–442.

By: J. MacKay*, A. Keung & S. Kumar*

Source: Crossref
Added: August 28, 2020

2012 journal article

Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells

Integrative Biology, 4(9), 1049–1058.

Source: Crossref
Added: August 28, 2020

2011 journal article

An Evolved Adeno-associated Viral Variant Enhances Gene Delivery and Gene Targeting in Neural Stem Cells

Molecular Therapy, 19(4), 667–675.

Source: Crossref
Added: August 28, 2020

2011 journal article

Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells

STEM CELLS, 29(11), 1886–1897.

By: A. Keung, E. de Juan-Pardo*, D. Schaffer* & S. Kumar*

author keywords: Neural stem cells; Cellular mechanotransduction; Rho GTP-binding proteins; Adipose stem cells; Extracellular matrix; Elastic modulus
Source: Crossref
Added: August 28, 2020

2010 journal article

A Genetic Strategy for Graded and Dynamic Control of Cell-Matrix Mechanobiology

Biophysical Journal, 98(3), 730a.

By: J. MacKay*, A. Keung & S. Kumar*

Source: Crossref
Added: August 28, 2020

2010 journal article

Biophysics and dynamics of natural and engineered stem cell microenvironments

Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2(1), 49–64.

Source: Crossref
Added: August 28, 2020

2010 journal article

Mechanotransductive Engineering of Neural Stem Cell Behavior

Biophysical Journal, 98(3), 404a–405a.

By: A. Keung, E. de Juan-Pardo, D. Schaffer & S. Kumar

Source: Crossref
Added: August 28, 2020

2007 journal article

Thermal Control of Amide Product Distributions at the Ge(100)-2×1 Surface

The Journal of Physical Chemistry C, 111(1), 411–419.

By: A. Keung, M. Filler* & S. Bent*

Source: Crossref
Added: August 28, 2020

2006 journal article

Carboxylic Acid Chemistry at the Ge(100)-2 × 1 Interface:  Bidentate Bridging Structure Formation on a Semiconductor Surface

Journal of the American Chemical Society, 128(3), 770–779.

Source: Crossref
Added: August 28, 2020

2005 journal article

Tertiary amide chemistry at the Ge(100)-2×1 surface

Surface Science, 599(1-3), 41–54.

author keywords: density functional calculations; vibrational spectroscopies; germanium; organic molecules; organo-functionalization of surfaces; desorption; amide; Ge(100)
Source: Crossref
Added: August 28, 2020