Adam Moeser Mackey, E., & Moeser, A. J. J. (2022). Sex Differences in Mast Cell-Associated Disorders: A Life Span Perspective. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 14(10). https://doi.org/10.1101/cshperspect.a039172 Mackey, E., Thelen, K. M., Bali, V., Fardisi, M., Trowbridge, M., Jordan, C. L., & Moeser, A. J. (2020). Perinatal androgens organize sex differences in mast cells and attenuate anaphylaxis severity into adulthood. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(38), 23751–23761. https://doi.org/10.1073/pnas.1915075117 D'Costa, S., Ayyadurai, S., Gibson, A. J., Mackey, E., Rajput, M., Sommerville, L. J., … Moeser, A. J. (2019). Mast cell corticotropin-releasing factor subtype 2 suppresses mast cell degranulation and limits the severity of anaphylaxis and stress-induced intestinal permeability. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 143(5), 1865-+. https://doi.org/10.1016/j.jaci.2018.08.053 Gonzalez, L. M., Moeser, A. J., & Blikslager, A. T. (2015). Animal models of ischemia-reperfusion-induced intestinal injury: progress and promise for translational research. American Journal of Physiology-Gastrointestinal and Liver Physiology, 308(2), G63–G75. https://doi.org/10.1152/ajpgi.00112.2013 Grilli, E., Tugnoli, B., Passey, J. L., Stahl, C. H., Piva, A., & Moeser, A. J. (2015). Impact of dietary organic acids and botanicals on intestinal integrity and inflammation in weaned pigs. BMC VETERINARY RESEARCH, 11. https://doi.org/10.1186/s12917-015-0410-0 Muthusamy, N., Sommerville, L. J., Moeser, A. J., Stumpo, D. J., Sannes, P., Adler, K., … Ghashghaei, H. T. (2015). MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. AGING CELL, 14(5), 764–773. https://doi.org/10.1111/acel.12354 Jacobi, S. K., Moeser, A. J., Blikslager, A. T., Rhoads, J. M., Corl, B. A., Harrell, R. J., & Odle, J. (2013). Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets. World Journal of Gastroenterology, 19(31), 5094–5102. https://doi.org/10.3748/wjg.v19.i31.5094 Onyiah, J. C., Sheikh, S. Z., Maharshak, N., Steinbach, E. C., Russo, S. M., Kobayashi, T., … Plevy, S. E. (2013). Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance. GASTROENTEROLOGY, 144(4), 789–798. https://doi.org/10.1053/j.gastro.2012.12.025 Lennon, E. M., Maharshak, N., Elloumi, H., Borst, L., Plevy, S. E., & Moeser, A. J. (2013). Early Life Stress Triggers Persistent Colonic Barrier Dysfunction and Exacerbates Colitis in Adult IL-10(-/-) Mice. INFLAMMATORY BOWEL DISEASES, 19(4), 712–719. https://doi.org/10.1097/mib.0b013e3182802a4e McLamb, B. L., Gibson, A. J., Overman, E. L., Stahl, C., & Moeser, A. J. (2013). Early Weaning Stress in Pigs Impairs Innate Mucosal Immune Responses to Enterotoxigenic E. coli Challenge and Exacerbates Intestinal Injury and Clinical Disease. PLOS ONE, 8(4). https://doi.org/10.1371/journal.pone.0059838 Cabrera, R. A., Usry, J. L., Arrellano, C., Nogueira, E. T., Kutschenko, M., Moeser, A. J., & Odle, J. (2013). Effects of creep feeding and supplemental glutamine or glutamine plus glutamate (Aminogut) on pre- and post-weaning growth performance and intestinal health of piglets. JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 4(1). https://doi.org/10.1186/2049-1891-4-29 Robbins, R. C., Artuso-Ponte, V. C., Moeser, A. J., Morrow, W. E. M., Spears, J. W., & Gebreyes, W. A. (2013). Effects of quaternary benzo(c)phenanthridine alkaloids on growth performance, shedding of organisms, and gastrointestinal tract integrity in pigs inoculated with multidrug-resistant Salmonella spp. American Journal of Veterinary Research, 74(12), 1530–1535. https://doi.org/10.2460/ajvr.74.12.1530 Stoeker, L. L., Overman, E. L., Nordone, S. K., Moeser, A. J., Simoes, R. D., & Dean, G. A. (2013). Infection with feline immunodeficiency Virus alters intestinal epithelial transport and mucosal immune responses to probiotics. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 153(1-2), 146–152. https://doi.org/10.1016/j.vetimm.2013.01.017 Overman, E. L., Rivier, J. E., & Moeser, A. J. (2012). CRF Induces Intestinal Epithelial Barrier Injury via the Release of Mast Cell Proteases and TNF-alpha. PLOS ONE, 7(6). https://doi.org/10.1371/journal.pone.0039935 Moeser, A. J., Borst, L. B., Overman, B. L., & Pittman, J. S. (2012). Defects in small intestinal epithelial barrier function and morphology associated with peri-weaning failure to thrive syndrome (PFTS) in swine. RESEARCH IN VETERINARY SCIENCE, 93(2), 975–982. https://doi.org/10.1016/j.rvsc.2012.01.003 Jacobi, S. K., Moeser, A. J., Corl, B. A., Harrell, R. J., Blikslager, A. T., & Odle, J. (2012). Dietary Long-Chain PUFA Enhance Acute Repair of Ischemia-Injured Intestine of Suckling Pigs. The Journal of Nutrition, 142(7), 1266–1271. https://doi.org/10.3945/jn.111.150995 Peace, R. M., Campbell, J., Polo, J., Crenshaw, J., Russell, L., & Moeser, A. (2011). Spray-Dried Porcine Plasma Influences Intestinal Barrier Function, Inflammation, and Diarrhea in Weaned Pigs. JOURNAL OF NUTRITION, 141(7), 1312–1317. https://doi.org/10.3945/jn.110.136796 Shan, T., Li, L., Simmonds, P., Wang, C., Moeser, A., & Delwart, E. (2011). The Fecal Virome of Pigs on a High-Density Farm. JOURNAL OF VIROLOGY, 85(22), 11697–11708. https://doi.org/10.1128/jvi.05217-11 Nighot, P. K., Moeser, A., Ali, R. A., Blikslager, A. T., & Koci, M. D. (2010). Astrovirus infection induces sodium malabsorption and redistributes sodium hydrogen exchanger expression. Virology, 401(2), 146–154. https://doi.org/10.1016/j.virol.2010.02.004 Smith, F., Clark, J. E., Overman, B. L., Tozel, C. C., Huang, J. H., Rivier, J. E. F., … Moeser, A. J. (2010). Early weaning stress impairs development of mucosal barrier function in the porcine intestine. American Journal of Physiology-Gastrointestinal and Liver Physiology, 298(3), G352–G363. https://doi.org/10.1152/ajpgi.00081.2009 Hansen, S. L., Ashwell, M. S., Moeser, A. J., Fry, R. S., Knutson, M. D., & Spears, J. W. (2010). High dietary iron reduces transporters involved in iron and manganese metabolism and increases intestinal permeability in calves. JOURNAL OF DAIRY SCIENCE, 93(2), 656–665. https://doi.org/10.3168/jds.2009-2341 Nighot, P. K., Moeser, A. J., Ryan, K. A., Ghashghaei, T., & Blikslager, A. T. (2009). ClC-2 is required for rapid restoration of epithelial tight junctions in ischemic-injured murine jejunum. Experimental Cell Research, 315(1), 110–118. https://doi.org/10.1016/j.yexcr.2008.10.001 Hansen, S. L., Trakooljul, N., Liu, H.-C., Moeser, A. J., & Spears, J. W. (2009). Iron Transporters Are Differentially Regulated by Dietary Iron, and Modifications Are Associated with Changes in Manganese Metabolism in Young Pigs. JOURNAL OF NUTRITION, 139(8), 1474–1479. https://doi.org/10.3945/jn.109.105866 Corl, B. A., Odle, J., Niu, X., Moeser, A. J., Gatlin, L. A., Phillips, O. T., … Rhoads, J. M. (2008). Arginine Activates Intestinal p70S6k and Protein Synthesis in Piglet Rotavirus Enteritis. The Journal of Nutrition, 138(1), 24–29. https://doi.org/10.1093/jn/138.1.24 Moeser, A. J., Nighot, P. K., Roerig, B., Ueno, R., & Blikslager, A. T. (2008). Comparison of the chloride channel activator lubiprostone and the oral laxative Polyethylene Glycol 3350 on mucosal barrier repair in ischemic-injured porcine intestine. World Journal of Gastroenterology, 14(39), 6012. https://doi.org/10.3748/wjg.14.6012 Moeser, A. J., Blikslager, A. T., & Swanson, C. (2008). Determination of minimum alveolar concentration of sevoflurane in juvenile swine. Research in Veterinary Science, 84(2), 283–285. https://doi.org/10.1016/j.rvsc.2007.03.015 Moeser, A. J., Nighot, P. K., Ryan, K. A., Simpson, J. E., Clarke, L. L., & Blikslager, A. T. (2008). Mice lacking the Na+/H+ exchanger 2 have impaired recovery of intestinal barrier function. American Journal of Physiology-Gastrointestinal and Liver Physiology, 295(4), G791–G797. https://doi.org/10.1152/ajpgi.00538.2007 Little, D., Brown, S. A., Campbell, N. B., Moeser, A. J., Davis, J. L., & Blikslager, A. T. (2007). Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum. American Journal of Veterinary Research, 68(6), 614–624. https://doi.org/10.2460/ajvr.68.6.614 Moeser, A. J., Ryan, K. A., Nighot, P. K., & Blikslager, A. T. (2007). Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs. American Journal of Physiology-Gastrointestinal and Liver Physiology, 293(2), G413–G421. https://doi.org/10.1152/ajpgi.00304.2006 Rhoads, J. M., Corl, B. A., Harrell, R., Niu, X., Gatlin, L., Phillips, O., … al. (2007). Intestinal ribosomal p70(S6K) signaling is increased in piglet rotavirus enteritis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(3), G913–G922. https://doi.org/10.1152/ajpgi.00468.2006 Moeser, A. J., & Blikslager, A. T. (2007). Mechanisms of porcine diarrheal disease. Journal of the American Veterinary Medical Association, 231(1), 56–67. https://doi.org/10.2460/javma.231.1.56 Muley, N. S., Heugten, E., Moeser, A. J., Rausch, K. D., & Kempen, T. A. T. G. (2007). Nutritional value for swine of extruded corn and corn fractions obtained after dry milling. JOURNAL OF ANIMAL SCIENCE, 85(7), 1695–1701. https://doi.org/10.2527/jas.2006-127 Moeser, A. J., Nighot, P. K., Engelke, K. J., Ueno, R., & Blikslager, A. T. (2007). Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone. American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(2), G647–G656. https://doi.org/10.1152/ajpgi.00183.2006 Blikslager, A. T., Moeser, A. J., Gookin, J. L., Jones, S. L., & Odle, J. (2007). Restoration of Barrier Function in Injured Intestinal Mucosa. Physiological Reviews, 87(2), 545–564. https://doi.org/10.1152/physrev.00012.2006 Moeser, A. J., Klok, C. V., Ryan, K. A., Wooten, J. G., Little, D., Cook, V. L., & Blikslager, A. T. (2007). Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig. American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(1), G173–G181. https://doi.org/10.1152/ajpgi.00197.2006 Moeser, A. J., Nighot, P. K., Ryan, K. A., Wooten, J. G., & Blikslager, A. T. (2006). Prostaglandin-mediated inhibition of Na+/H+ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine. American Journal of Physiology-Gastrointestinal and Liver Physiology, 291(5), G885–G894. https://doi.org/10.1152/ajpgi.00380.2005 Kempen, T. A. T. G., Heugten, E., Moeser, A. J., Muley, N. S., & Sewalt, V. J. H. (2006). Selecting soybean meal characteristics preferred for swine nutrition. JOURNAL OF ANIMAL SCIENCE, 84(6), 1387–1395. https://doi.org/10.2527/2006.8461387x Moeser, A. J., Haskell, M. M., Shifflett, D. E., Little, D., Schultz, B. D., & Blikslager, A. T. (2004). CIC-2 chloride secretion mediates prostaglandin-induced recovery of barrier function in ischemia-injured porcine ileum. GASTROENTEROLOGY, 127(3), 802–815. https://doi.org/10.1053/j.gastro.2004.06.004 Shifflett, D. E., Jones, S. L., Moeser, A. J., & Blikslager, A. T. (2004). Mitogen-activated protein kinases regulate COX-2 and mucosal recovery in ischemic-injured porcine ileum. American Journal of Physiology-Gastrointestinal and Liver Physiology, 286(6), G906–G913. https://doi.org/10.1152/ajpgi.00478.2003 Shifflett, D. E., Bottone, F. G., Jr., Young, K. M., Moeser, A. J., Jones, S. L., & Blikslager, A. T. (2004). Neutrophils augment recovery of porcine ischemia-injured ileal mucosa by an IL-1β- and COX-2-dependent mechanism. American Journal of Physiology-Gastrointestinal and Liver Physiology, 287(1), G50–G57. https://doi.org/10.1152/ajpgi.00076.2003 Moeser, A. J., See, M. T., Heugten, E., Morrow, W. E. M., & Kempen, T. V. (2003). Diet and evaluators affect perception of swine waste odor: An educational demonstration. Journal of Animal Science, 81(12), 3211–3215. https://doi.org/10.2527/2003.81123211x Moeser, A. J., & Kempen, T. A. T. G. (2002). Dietary fibre level and enzyme inclusion affect nutrient digestibility and excreta characteristics in grower pigs. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 82(14), 1606–1613. https://doi.org/10.1002/jsfa.1234 Moeser, A. J., Kim, I. B., Heugten, E., & Kempen, T. V. (2002). The nutritional value of degermed, dehulled corn for pigs and its impact on the gastrointestinal tract and nutrient excretion. Journal of Animal Science, 80(10), 2629–2638. https://doi.org/10.2527/2002.80102629x Nighot, M., Moeser, A., Ueno, R., & Blikslager, A. Gastro protective properties of the novel prostone SPI-8811 against acid-injured porcine mucosa. World Journal of Gastroenterology, 18(34), 4684–4692.