Arianna George

Works (4)

Updated: July 7th, 2023 21:20

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

By: K. Popowski n , A. Moatti n , G. Scull n, D. Silkstone n, H. Lutz  n, B. López de Juan Abad  n, A. George n , E. Belcher  n ...

topics (OpenAlex): Extracellular vesicles in disease; RNA Interference and Gene Delivery; Inhalation and Respiratory Drug Delivery
TL;DR: The results suggest that extracellular vesicles can serve as an inhaled mRNA drug-delivery system that is superior to synthetic liposomes. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 17, 2022

2021 article

Exosome therapeutics for COVID‐19 and respiratory viruses

Popowski, K. D., Dinh, P. U. C., George, A., Lutz, H., & Cheng, K. (2021, January 31). View, Vol. 1, p. 20200186.

By: K. Popowski n , P. Dinh n, A. George n , H. Lutz  n & K. Cheng n

author keywords: COVID-19; exosomes; respiratory viruses; SARS-CoV-2
topics (OpenAlex): Extracellular vesicles in disease; COVID-19 Impact on Reproduction; Respiratory viral infections research; SARS-CoV-2 and COVID-19 Research; Long-Term Effects of COVID-19
TL;DR: The relationship between exosomes and respiratory viruses is reviewed, potential exosome therapeutics for viral infections are described, and progress toward clinical translation for lung‐derived exosomal therapeutics is summarized. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 19, 2021

2020 article

Exosome therapeutics for lung regenerative medicine

Popowski, K., Lutz, H., Hu, S., George, A., Dinh, P. U., & Cheng, K. (2020, June 29). Journal of Extracellular Vesicles, Vol. 9, p. 1785161.

By: K. Popowski n , H. Lutz  n, S. Hu n , A. George n , P. Dinh n & K. Cheng n

author keywords: Exosome; regenerative medicine; lung spheroid cell; stem cell
topics (OpenAlex): Extracellular vesicles in disease; MicroRNA in disease regulation; Circular RNAs in diseases
TL;DR: The uses of exosomes as a therapy and their roles in lung regenerative medicine, as well as current challenges in exosome therapies are underline. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 20, 2020

2020 article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

Dinh, P.-U. C., Paudel, D., Brochu, H., Popowski, K. D., Gracieux, M. C., Cores, J., … Cheng, K. (2020, February 28). Nature Communications, Vol. 11.

By: P. Dinh n, D. Paudel n, H. Brochu n , K. Popowski n , M. Gracieux n, J. Cores n, K. Huang n , M. Hensley n ...

MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
topics (OpenAlex): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis; Medical Imaging and Pathology Studies; Extracellular vesicles in disease
TL;DR: It is shown that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 23, 2020

Education

Updated: September 26th, 2023 16:58

2022 - present

Duke University Durham, North Carolina, US
Duke Physician Assistant Program

2017 - 2020

North Carolina State University Raleigh, NC, US
Human Biology, B.S. Biological Sciences

2017 - 2020

North Carolina State University Raleigh, NC, US
Biochemistry, B.S. Molecular and Structural Biochemistry

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