Works (4)
Updated: July 7th, 2023 21:20
2022 journal article
Inhalable dry powder mRNA vaccines based on extracellular vesicles
Matter, 5(9), 2960–2974.
TL;DR:
The results suggest that extracellular vesicles can serve as an inhaled mRNA drug-delivery system that is superior to synthetic liposomes.
(via Semantic Scholar)
open access via www.cell.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 17, 2022
2021 review
Exosome therapeutics for COVID-19 and respiratory viruses
[Review of ]. VIEW, 2(3).
author keywords: COVID-19; exosomes; respiratory viruses; SARS-CoV-2
TL;DR:
The relationship between exosomes and respiratory viruses is reviewed, potential exosome therapeutics for viral infections are described, and progress toward clinical translation for lung‐derived exosomal therapeutics is summarized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 19, 2021
2020 review
Exosome therapeutics for lung regenerative medicine
[Review of ]. JOURNAL OF EXTRACELLULAR VESICLES, 9(1).
author keywords: Exosome; regenerative medicine; lung spheroid cell; stem cell
TL;DR:
The uses of exosomes as a therapy and their roles in lung regenerative medicine, as well as current challenges in exosome therapies are underline.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 20, 2020
2020 journal article
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
NATURE COMMUNICATIONS, 11(1).
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
TL;DR:
It is shown that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 23, 2020
Education
Updated: September 26th, 2023 16:58
2022 - present
Duke University Durham, North Carolina, US
Duke Physician Assistant Program
2017 - 2020
North Carolina State University Raleigh, NC, US
Human Biology, B.S.
Biological Sciences
2017 - 2020
North Carolina State University Raleigh, NC, US
Biochemistry, B.S.
Molecular and Structural Biochemistry
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