Works (4)

Updated: July 5th, 2023 15:42

2017 journal article

Structural studies of Neurospora crassa LPMO9D and redox partner CDHIIA using neutron crystallography and small-angle scattering


By: A. Bodenheimer n, . William B. O'Dell n, C. Stanley* & F. Meilleur n

author keywords: Polysaccharide monooxygenases; Cellobiose dehydrogenases; Neutron diffraction; Neutron scattering; X-ray induced photoreduction
MeSH headings : Carbohydrate Dehydrogenases / chemistry; Carbohydrate Dehydrogenases / metabolism; Catalytic Domain; Crystallography, X-Ray; Mixed Function Oxygenases / chemistry; Mixed Function Oxygenases / metabolism; Models, Molecular; Neurospora crassa / enzymology; Oxidation-Reduction; Scattering, Small Angle
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states

FEBS LETTERS, 590(23), 4429–4438.

By: A. Bodenheimer n & F. Meilleur n

author keywords: Cel7A; cellulase; closed state; processivity; product-binding site; Trichoderma reesei
MeSH headings : Binding Sites; Catalytic Domain; Crystallography, X-Ray; Glycoside Hydrolases / chemistry; Glycoside Hydrolases / genetics; Glycoside Hydrolases / metabolism; Molecular Dynamics Simulation; Mutation; Trichoderma / enzymology
TL;DR: Analysis of the interactions formed by R251 provides a structural rationale for the concurrent decrease in product inhibition and catalytic efficiency measured for product‐binding site mutants. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Neutron protein crystallography: A complementary tool for locating hydrogens in proteins


By: . William B. O'Dell n, A. Bodenheimer n & F. Meilleur n

author keywords: Neutron; Crystallography; Hydrogen; Enzyme; Protonation; Water
TL;DR: Methods to produce isotopically-substituted proteins and to grow large crystals are provided in the context of neutron structures reported in the literature along with technique-specific strategies including joint X-ray/neutron structure refinement. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms


By: A. Bodenheimer n, M. Cuneo*, P. Swartz n, J. He*, H. O'Neill*, D. Myles*, B. Evans*, F. Meilleur n, F. Section

MeSH headings : Cellulose 1,4-beta-Cellobiosidase / chemistry; Crystallization; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Hypocrea / chemistry
TL;DR: A preliminary analysis of the electron-density maps suggests that the linker and CBM are disordered in both crystal forms of Cel7A, which consists of a large 434-residue N-terminal catalytic domain capable of cleaving cellulose, a 27-Residue flexible linking module and a small 36- Residue C-Terminal carbohydrate-binding module. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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