Arianna Minzoni

Chemical & Biomolecular G&T

Works (7)

Updated: January 23rd, 2026 08:05

2026 article

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Idanwekhai, K. P., Shastry, S., Hurst, M. R., Minzoni, A., Barbieri, E., Remmler, L., … Tropsha, A. (2026, January 19). Biotechnology and Bioengineering, Vol. 1.

By: K. Idanwekhai *, S. Shastry n, M. Hurst n, A. Minzoni n, E. Barbieri*, L. Remmler*, E. Muratov, M. Daniele n , S. Menegatti n , A. Tropsha

Contributors: K. Idanwekhai *, S. Shastry n, M. Hurst n, A. Minzoni n, E. Barbieri*, L. Remmler*, E. Muratov, . al.

topics (OpenAlex): Protein purification and stability; Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: January 21, 2026

2025 journal article

Developing a process of lentivirus purification from recombinant fluids using peptide affinity ligands

Bioengineering & Translational Medicine, 10(6).

By: E. Barbieri n, G. Mollica n, S. Sripada n, S. Shastry n, Y. Wu n, A. Minzoni n, W. Smith n, E. Wuestenhagen* ...

author keywords: affinity chromatography; lentivirus; membrane chromatography; peptide ligands; product polishing
topics (OpenAlex): Virus-based gene therapy research; CAR-T cell therapy research; Viral Infectious Diseases and Gene Expression in Insects
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 14, 2025

2025 journal article

Integrating Affinity Chromatography in the Platform Process for Adenovirus Purification

Biotechnology and Bioengineering, 122(7), 1780–1792.

By: Y. Wu n, E. Barbieri n, W. Smith n, A. Minzoni n, R. Kilgore n, W. Chu n, M. Daniele n , S. Menegatti n 

Contributors: Y. Wu n, E. Barbieri n, W. Smith n, A. Minzoni n, R. Kilgore n, W. Chu n, M. Daniele n , S. Menegatti n 

author keywords: adenovirus; affinity chromatography; biomanufacturing; bioseparations; gene therapy
topics (OpenAlex): Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects; Viral gastroenteritis research and epidemiology
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: May 6, 2025

2025 article

Integrating affinity chromatography in the platform process for Adenovirus purification

Wu, Y., Barbieri, E., Smith, W. K., Minzoni, A., Kilgore, R. E., Chu, W., … Menegatti, S. (2025, April 5). (Vol. 4). Vol. 4.

By: Y. Wu n, E. Barbieri*, W. Smith n, A. Minzoni n, R. Kilgore n, W. Chu n, M. Daniele n , S. Menegatti n 

Contributors: Y. Wu n, E. Barbieri*, W. Smith n, A. Minzoni n, R. Kilgore n, W. Chu n, M. Daniele n , S. Menegatti n 

topics (OpenAlex): Viral Infectious Diseases and Gene Expression in Insects; Protein purification and stability; Virus-based gene therapy research
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: January 18, 2026

2024 journal article

Serotype-agnostic affinity purification of adeno-associated virus (AAV) via peptide-functionalized chromatographic resins

Journal of Chromatography A, 1734, 465320.

By: S. Shastry n, E. Barbieri n, A. Minzoni n, W. Chu n, S. Johnson n, M. Stoops n, J. Pancorbo n, G. Gilleskie n  ...

Contributors: S. Shastry n, E. Barbieri n, A. Minzoni n, W. Chu n, S. Johnson n, M. Stoops n, J. Pancorbo n, . al.

author keywords: Gene therapy; Adeno-associated virus; Peptide ligands; Affinity chromatography; Transduction activity
MeSH headings : Dependovirus / isolation & purification; Dependovirus / genetics; Dependovirus / chemistry; Chromatography, Affinity / methods; Peptides / chemistry; Peptides / isolation & purification; Serogroup; Humans; Hydrogen-Ion Concentration; Genetic Vectors; HEK293 Cells
topics (OpenAlex): Virus-based gene therapy research; RNA Interference and Gene Delivery; Viral Infectious Diseases and Gene Expression in Insects
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: September 1, 2024

2023 journal article

Rational design and experimental evaluation of peptide ligands for the purification of adeno‐associated viruses via affinity chromatography

Biotechnology Journal, 19(1).

By: S. Shastry n, W. Chu n, E. Barbieri n, P. Greback‐Clarke n, W. Smith  n, C. Cummings n, A. Minzoni n, J. Pancorbo n ...

Contributors: S. Shastry n, W. Chu n, E. Barbieri n, P. Greback-Clarke n, W. Smith  n, C. Cummings n, A. Minzoni n, . al.

author keywords: adeno-associated virus; affinity chromatography; gene therapy; peptide ligands; transduction activity
MeSH headings : Humans; Dependovirus / genetics; Capsid / chemistry; HEK293 Cells; Transduction, Genetic; Peptides / metabolism; Ligands; Chromatography, Affinity; Genetic Vectors / genetics
topics (OpenAlex): Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects; CAR-T cell therapy research
TL;DR: This study introduces a cohort of peptide ligands that mimic the biorecognition activity of the AAV receptor (AAVR) and anti-AAV antibody A20, enable product elution under near-physiological conditions (pH 6.0) and grant extended reusability by withstanding multiple regenerations. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 10, 2023

2023 article

The downstream bioprocess toolbox for therapeutic viral vectors

Kilgore, R., Minzoni, A., Shastry, S., Smith, W., Barbieri, E., Wu, Y., … Menegatti, S. (2023, September 9). Journal of Chromatography A, Vol. 1709.

By: R. Kilgore n, A. Minzoni n, S. Shastry n, W. Smith n, E. Barbieri n, Y. Wu n, J. LeBarre n, W. Chu n, J. O'Brien n, S. Menegatti n 

author keywords: Viral vectors; Gene therapy; Affinity ligands; Chromatography; Adsorbents; AAV
topics (OpenAlex): Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects; Bacteriophages and microbial interactions
TL;DR: This study presents a comprehensive overview of the downstream bioprocess toolbox for viral vectors established in the last decade, and discusses present efforts and future directions contributing to the success of this promising class of biological medicines. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 30, 2023

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