Works (44)

Updated: July 15th, 2024 04:39

2024 journal article

An 18-μm microaggregate blood filter does not cause hemolysis during in vitro whole blood transfusions in sea turtles

AMERICAN JOURNAL OF VETERINARY RESEARCH, 85(5).

By: N. Dannemiller n, A. Lynch n, E. Christiansen n & C. Harms n

author keywords: erythrocyte; hematology; red blood cell morphology; sea turtle rehabilitation; transfusion medicine
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 28, 2024

2024 journal article

INVESTIGATION OF A POINT-OF-CARE VISCOELASTIC COAGULATION MONITOR AND ITS COMPARISON TO THROMBOELASTOGRAPHY IN CLINICALLY HEALTHY AFRICAN ELEPHANTS (<i>LOXODONTA AFRICANA</i>)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 55(1), 164–172.

By: A. Heniff n, A. Lynch n, L. Ruterbories n, L. Minter n, T. Georoff n & J. Balko n

Sources: Web Of Science, NC State University Libraries
Added: May 20, 2024

2024 journal article

Pharmacokinetics of a continuous intravenous infusion of hydromorphone in healthy dogs

FRONTIERS IN VETERINARY SCIENCE, 11.

By: C. Wimbish n, A. Lynch n, H. Knych*, Y. Ueda n & K. Messenger n

author keywords: constant rate infusion; hydromorphone; dog; pharmacokinetics; pain; opioid
Sources: Web Of Science, NC State University Libraries
Added: July 8, 2024

2023 journal article

Case report: Laryngospasm following ethanol ablation of a parathyroid nodule in a dog with primary hyperparathyroidism

FRONTIERS IN VETERINARY SCIENCE, 10.

By: K. Rank n, A. Lynch n, R. Green n, L. Reed-Jones n, K. Harrell n & Y. Ueda n

author keywords: iatrogenic; hyperparathyroidism; hypocalcemia; ethanol ablation; laryngospasm
TL;DR: To the authors' knowledge, this is the first description of laryngospasm following ethanol ablation of a parathyroid nodule in a dog that developed hypocalcemia. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 19, 2023

2023 journal article

Evaluation of thrombin generation in dogs administered clopidogrel

Frontiers in Veterinary Science, 10.

By: K. Rank n, A. Lynch n, L. Ruterbories n, R. Li n & Y. Ueda n

author keywords: coagulation; platelet inhibitory; antithrombotic; therapeutic monitoring; canine
TL;DR: Thrombin generation performed on platelet poor plasma may not be a useful antiplatelet monitoring tool in dogs, despite concomitant changes in TEG-PM variables consistent with platelet inhibition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: September 11, 2023

2023 article

Hemostatic profiles in dogs with sudden acquired retinal degeneration syndrome

Lynch, A. M. M., Ruterbories, L. K. K., Robertson, J. B. B., Lunn, K. F. F., & Mowat, F. M. M. (2023, April 19). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 4.

By: A. Lynch n, L. Ruterbories n, J. Robertson n, K. Lunn n & F. Mowat n

author keywords: coagulation; fibrinogen; hypercoagulability; SARDS
MeSH headings : Dogs; Animals; Retinal Degeneration / veterinary; Case-Control Studies; Hemostatics; Pilot Projects; Thrombophilia / complications; Thrombophilia / veterinary; Fibrinogen; Antithrombins; Thrombelastography / veterinary; Dog Diseases
TL;DR: Hypercoagulability was common in both dogs with SARDS and controls, but dogs with ARDS were significantly more hypercoagULable on TEG, which remains to be determined. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 20, 2023

2023 journal article

Persistent spontaneous pneumomediastinum in a dog with pulmonary fibrosis

VETERINARY RECORD CASE REPORTS, 8.

By: S. Amirsultan n, A. Lynch n, D. Meritet n & N. Nelson n

author keywords: dogs; histopathology; radiography; respiratory disease
TL;DR: A 5‐year‐old, 5.8‐kg, neutered, male, mix‐breed dog was presented to the emergency service of a university hospital for assessment of respiratory distress, with a diagnosis of interstitial pulmonary fibrosis made at postmortem examination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023

2022 journal article

2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1‐ Defining populations at risk

Journal of Veterinary Emergency and Critical Care, 32(3), 289–314.

By: A. deLaforcade*, L. Bacek*, M. Blais*, C. Boyd*, B. Brainard*, D. Chan*, S. Cortellini*, R. Goggs* ...

author keywords: arrhythmias; heartworm disease; protein-losing enteropathy; vascular devices
MeSH headings : Adrenocortical Hyperfunction / drug therapy; Adrenocortical Hyperfunction / veterinary; Anemia, Hemolytic, Autoimmune / drug therapy; Anemia, Hemolytic, Autoimmune / veterinary; Animals; Cat Diseases / drug therapy; Cat Diseases / epidemiology; Cats; Consensus; Critical Care; Dirofilariasis; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dogs; Fibrinolytic Agents / therapeutic use; Protein-Losing Enteropathies / drug therapy; Protein-Losing Enteropathies / veterinary; Risk Factors; Sepsis / veterinary; Thrombosis / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: May 16, 2022

2022 journal article

2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 6: Defining rational use of thrombolytics

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 32(4), 446–470.

By: C. Sharp*, M. Blais*, C. Boyd*, B. Brainard*, D. Chan*, A. Laforcade*, R. Goggs*, J. Guillaumin* ...

author keywords: anticoagulant; antiplatelet agent; cats; dogs; thrombosis
MeSH headings : Animals; Anticoagulants / therapeutic use; Cat Diseases / drug therapy; Cats; Consensus; Critical Care; Dog Diseases / drug therapy; Dogs; Fibrinolytic Agents / therapeutic use; Tissue Plasminogen Activator / therapeutic use; Venous Thrombosis / drug therapy; Venous Thrombosis / veterinary
TL;DR: Substantial additional research is needed to address the role of thrombolytics for the treatment of arterial and venous thrombosis in dogs and cats. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 8, 2022

2022 article

Clinical features and posttreatment monitoring of dogs administered rivaroxaban (2018-2020): 19 cases

Tracy, A. L., Goggs, R., Brooks, M. B., & Lynch, A. M. (2022, April 20). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 4.

By: A. Tracy n, R. Goggs*, M. Brooks* & A. Lynch n

author keywords: anticoagulant; canine; thromboprophylaxis; venous thrombosis
MeSH headings : Animals; Anticoagulants; Clopidogrel / therapeutic use; Dog Diseases / drug therapy; Dogs; Factor Xa Inhibitors / therapeutic use; Humans; Retrospective Studies; Rivaroxaban / therapeutic use; Thrombosis / drug therapy; Thrombosis / veterinary
TL;DR: Dogs in this study received a range of rivaroxaban dosages and attained variable aXa values that were not directly correlated with dosage and there were also no significant differences in baseline clinicopathological variables in dogs in which a Xa fell within or outside this range. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022

2022 article

Outcomes of 434 dogs with non-steroidal anti-inflammatory drug toxicosis treated with fluid therapy, lipid emulsion, or therapeutic plasma exchange

Chalifoux, N. V., Butty, E. M., Mauro, K. D., Moyle, R. B., Ehrhardt, C. M., Robertson, J. B., … Lynch, A. M. (2022, December 1). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 12.

By: N. Chalifoux*, E. Butty*, K. Mauro*, R. Moyle, C. Ehrhardt*, J. Robertson n, M. Labato*, C. Culler ...

Contributors: J. Robertson n

author keywords: carprofen; ibuprofen; ILE; intoxication; naproxen; NSAID; TPE
MeSH headings : Dogs; Animals; Ibuprofen / adverse effects; Plasma Exchange / veterinary; Retrospective Studies; Creatinine; Emulsions / adverse effects; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Fluid Therapy / veterinary; Dog Diseases / chemically induced; Dog Diseases / therapy; Dog Diseases / diagnosis; Lipids
TL;DR: Despite similar outcomes of lower incidence of AKI in the TPE group, and slightly lower maximal creatinine concentration in dogs treated with ILE vs IVF alone, ILE and TPE should be considered in the management of severe NSAID toxicosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 7, 2022

2022 article

Outcomes of nonsteroidal anti-inflammatory drug toxicosis treated with therapeutic plasma exchange in 62 dogs

Butty, E. M., Suter, S. E., Chalifoux, N. V., Lynch, A. M., Mauro, K. D., Moyle, R. B., … Labato, M. A. (2022, August 5). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 8.

By: E. Butty*, S. Suter n, N. Chalifoux*, A. Lynch n, K. Mauro*, R. Moyle, C. Ehrhardt*, J. Robertson n ...

author keywords: carprofen; ibuprofen; naproxen; NSAID; TPE
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Dog Diseases / drug therapy; Dog Diseases / therapy; Dogs; Drug Overdose / therapy; Drug Overdose / veterinary; Ibuprofen / adverse effects; Naproxen / therapeutic use; Plasma Exchange / veterinary; Retrospective Studies
TL;DR: This population of dogs managed with TPE had excellent outcomes, even in cases of high NSAID dose ingestion, when TPE is available and the time frame is appropriate, this extracorporeal modality should be considered for the management of NSAID overdose. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 15, 2022

2022 journal article

Point-of-care viscoelastic coagulation assessment in healthy dogs during the perianesthetic period

BMC VETERINARY RESEARCH, 18(1).

By: W. Wang n, A. Lynch n, J. Balko n, D. Duffy n, J. Robertson n & L. Posner n

author keywords: Coagulation; Viscoelastic testing; VCM Vet; Perianesthetic period
MeSH headings : Animals; Blood Coagulation; Blood Coagulation Tests / veterinary; Dogs; Fibrinolysis; Point-of-Care Systems; Thrombelastography / veterinary
TL;DR: The rate of clot formation (CT and CFT) decreased over the perianesthetic period in healthy dogs undergoing surgery and there was clinically acceptable consistency between devices. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: September 26, 2022

2021 article

Clinical features, outcome, and illness severity scoring in 32 dogs with urosepsis (2017-2018)

Perry, K. M., Lynch, A. M., Caudill, A., Vigani, A., Roberston, J. B., & Vaden, S. (2021, November 3). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 11.

By: K. Perry n, A. Lynch n, A. Caudill n, A. Vigani*, J. Roberston n & S. Vaden n

author keywords: APPLE score; canine; infection; MODS
MeSH headings : Animals; Dog Diseases / diagnosis; Dogs; Male; Multiple Organ Failure / veterinary; Patient Acuity; Retrospective Studies; Sepsis / diagnosis; Sepsis / veterinary
TL;DR: Survition of dogs with urosepsis was good and may be higher than for other sources of sepsis, and compared to survivors, nonsurvivors had more dysfunctional organs and higher illness severity scores, which may be helpful in the assessment and management of Dogs with u rosepsis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 15, 2021

2021 journal article

Evaluation of point-of-care coagulation tests as alternatives to anti-Xa activity for monitoring the anticoagulant effects of rivaroxaban in healthy dogs

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 31(1), 18–24.

By: A. Lynch n, L. Ruterbories n, E. Griffith n, R. Hanel*, A. Stablein* & M. Brooks*

author keywords: anticoagulant; antithrombotic; canine direct oral anticoagulants; thromboembolism
MeSH headings : Administration, Oral; Animals; Anticoagulants / administration & dosage; Anticoagulants / pharmacology; Blood Coagulation / drug effects; Blood Coagulation Tests / veterinary; Dogs; Factor Xa Inhibitors / administration & dosage; Factor Xa Inhibitors / pharmacology; Male; Partial Thromboplastin Time / veterinary; Point-of-Care Testing; Prospective Studies; Prothrombin Time / veterinary; Reference Values; Rivaroxaban / administration & dosage; Rivaroxaban / pharmacology; Thrombelastography / veterinary
TL;DR: Of all the coagulation tests investigated, the PT correlated best with RIVA, and there is potential for PT being a convenient second-line monitoring option in dogs receiving rivaroxaban, but further work is necessary to validate other PT assays. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 16, 2020

2021 article

Influence of long-stay jugular catheters on hemostatic variables in healthy dogs

Kielb Basile, J. L., Lynch, A. M., Ruterbories, L., Castaneda, K., Griffith, E., & Ueda, Y. (2021, July 3). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 7.

By: J. Kielb Basile, A. Lynch n, L. Ruterbories n, K. Castaneda n, E. Griffith n & Y. Ueda n

author keywords: canine; central venous catheter; hemostasis; thromboelastography; venipuncture
MeSH headings : Animals; Catheters, Indwelling / adverse effects; Catheters, Indwelling / veterinary; Dogs; Hemostatics; Jugular Veins; Male; Partial Thromboplastin Time / veterinary; Prospective Studies; Prothrombin Time / veterinary
TL;DR: The data suggest that accurate hemostatic variables may be obtained using blood collected from indwelling jugular catheters, maintained with heparinized saline for at least 72 hours, in healthy dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 12, 2021

2021 article

Non-cardiogenic pulmonary oedema and multisystemic haemorrhage secondary to an accidental intravenous injection of melarsomine in a dog

Wolf, J., Law, J. M., & Lynch, A. (2021, September 29). VETERINARY RECORD CASE REPORTS, Vol. 9.

By: J. Wolf n, J. Law n & A. Lynch n

author keywords: canine; dirofilariasis treatment; drug error
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 12, 2021

2021 journal article

SAFETY OF MULTIPLE-DOSE INTRAMUSCULAR KETOPROFEN TREATMENT IN LOGGERHEAD TURTLES (CARETTA CARETTA)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 52(1), 126–132.

By: C. Harms n, L. Ruterbories n, N. Stacy*, E. Christiansen n, M. Papich n, A. Lynch n, A. Barratclough*, M. Serrano n

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Drug Administration Schedule; Ketoprofen / administration & dosage; Ketoprofen / adverse effects; Ketoprofen / therapeutic use; Thrombelastography; Turtles / blood
TL;DR: Ketoprofen at 2 mg/kg IM q24hr for up to 5 days in loggerheads appears safe with respect to blood clotting and blood data, although other potential effects were not evaluated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 24, 2021

2021 journal article

The influence of feeding and gastroprotectant medications on the Factor Xa inhibitory activity of orally administered rivaroxaban in normal dogs

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 31(1), 59–65.

By: A. Lynch n, L. Ruterbories n, E. Griffith n, R. Hanel*, A. Stablein* & M. Brooks*

author keywords: anticoagulant; antithrombotic; canine direct oral anticoagulants; thromboembolism
MeSH headings : Administration, Oral; Animals; Anti-Ulcer Agents / administration & dosage; Anti-Ulcer Agents / pharmacology; Anticoagulants / administration & dosage; Anticoagulants / pharmacokinetics; Blood Coagulation Tests / veterinary; Dogs; Factor Xa Inhibitors / administration & dosage; Factor Xa Inhibitors / pharmacokinetics; Male; Meals; Prospective Studies; Reference Values; Rivaroxaban / administration & dosage; Rivaroxaban / pharmacokinetics
TL;DR: Based on results, dogs treated with rivaroxaban do not require special modification of feeding practices or gastroprotectant drug administration and clinically relevant differences among treatment groups were not identified in combined analyses of time points. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 16, 2020

2021 article

Use of a polyethylene glycol solution for the management of sand impaction in three dogs

Johnson, R., Wigglesworth, S., Moyle, R., & Lynch, A. (2021, June 19). VETERINARY RECORD CASE REPORTS, Vol. 6.

By: R. Johnson n, S. Wigglesworth*, R. Moyle* & A. Lynch n

author keywords: critical care; dogs; emergency medicine; fluid therapy
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 28, 2021

2021 article

Use of extracorporeal therapy in a dog with heatstroke

Tracy, A., Lynch, A., Messenger, K., Vaden, S., & Vigani, A. (2021, December 14). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 12.

By: A. Tracy n, A. Lynch n, K. Messenger n, S. Vaden n & A. Vigani*

author keywords: cytokines; extracorporeal therapy; heatstroke; hemodialysis; hemoperfusion
MeSH headings : Acute Kidney Injury / veterinary; Animals; Cytokines; Dog Diseases / therapy; Dogs; Heat Stroke / therapy; Heat Stroke / veterinary; Hemoperfusion / veterinary; Male
TL;DR: To the authors' knowledge, this represents the first clinical use of ECT consisting of HD and cytokine adsorption in the management of severe heat-related illness in a dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 20, 2021

2020 journal article

Capsule endoscopy detects insufficient treatment of gastric bleeding in a dog with chronic hepatitis

VETERINARY RECORD CASE REPORTS, 8(4).

By: M. Tolbert*, A. Spencer n, A. Lynch n, M. Papich n & J. Lidbury*

author keywords: omeprazole; canine; rivaroxaban; portal hypertension
TL;DR: Substantial upper GI bleeding persisted despite excellent gastric acid suppression, bringing into question the value of routinely recommending such therapy in dogs with hepatic failure without additional monitoring for adequacy of treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020

2020 journal article

Evaluation of an emergency medicine-focused clinical pathology training course for non-clinical pathology house officers

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 30(2), 165–169.

By: S. Pavlides*, A. Lynch n, K. Snowden* & M. Leissinger*

author keywords: education; emergency diagnostics; clinical pathology proficiency
MeSH headings : Animals; Clinical Competence / standards; Curriculum; Education, Veterinary; Emergency Medicine / education; Humans; Pathology, Clinical / education; Prospective Studies; Surveys and Questionnaires; Veterinarians
TL;DR: This study identified that a 4-hour clinical pathology training course relevant to small animal emergency medicine improved the knowledge and confidence of nonclinical pathology house officers and may prove helpful to improve the proficiency of emergency veterinarians. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 10, 2020

2020 journal article

Extrahepatic biliary tract obstruction secondary to a diaphragmatic rent in a dog

VETERINARY RECORD CASE REPORTS, 8(2).

By: M. Granick*, A. Lynch n & E. Cohen n

TL;DR: A 13-month-old intact female Akita was referred to a specialty hospital with suspected pancreatitis and exploratory coeliotomy identified a right dorsolateral diaphragmatic rent with pyloric, proximal duodenal, right pancreatic and associated omental entrapment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 8, 2021

2020 journal article

Intervertebral disc disease and aortic thromboembolism are the most common causes of acute paralysis in dogs and cats presenting to an emergency clinic

VETERINARY RECORD, 187(10).

By: G. Rossi n, A. Stachel n, A. Lynch n & N. Olby n

MeSH headings : Animals; Cat Diseases / epidemiology; Cats; Dog Diseases / epidemiology; Dogs; Emergency Service, Hospital; Female; Intervertebral Disc Degeneration / epidemiology; Intervertebral Disc Degeneration / veterinary; Intervertebral Disc Displacement / epidemiology; Intervertebral Disc Displacement / veterinary; Male; North Carolina / epidemiology; Paralysis / etiology; Paralysis / veterinary; Prevalence; Records / veterinary; Thromboembolism / epidemiology; Thromboembolism / veterinary
TL;DR: IVDD and ATE are the overwhelming causes of acute paralysis in dogs and cats, respectively, with approximately 28% of dogs and 40 per cent of cats having a different diagnosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 15, 2021

2020 journal article

Outcome and treatments of dogs with aortic thrombosis: 100cases(1997-2014)

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(5), 1759–1767.

By: M. Ruehl*, A. Lynch n, . Therese E. O'Toole*, B. Morris*, J. Rush*, C. Couto, S. Hmelo, S. Sonnenshein, A. Butler, J. Guillaumin*

author keywords: canine; protein-losing nephropathy; saddle thrombus; thromboembolism; thrombus
MeSH headings : Animals; Blood Coagulation Tests / veterinary; Dog Diseases / drug therapy; Dogs; Proteinuria / veterinary; Retrospective Studies; Thrombosis / veterinary
TL;DR: Dogs with ATh have a poor prognosis, with nonambulatory dogs at the time of presentation having worse outcome, and ambulation status at thetime of presentation was significantly correlated with survival‐to‐discharge. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 31, 2020

2020 journal article

The influence of packed cell volume versus plasma proteins on thromboelastographic variables in canine blood

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 30(4), 418–425.

By: A. Lynch n, L. Ruterbories n, J. Jack n, A. Motsinger-Reif n & R. Hanel*

MeSH headings : Animals; Blood Coagulation Tests / veterinary; Blood Proteins / physiology; Cell Size; Dogs / blood; Female; Fibrinogen / metabolism; Hematocrit / veterinary; Male; Thrombelastography / veterinary
TL;DR: In an ex vivo model, plasma proteins but not PCV impacted TEG variables, suggesting that TEG changes noted with anemia are imparted by changes in available fibrinogen in a fixed microenvironment rather than artifact of anemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 13, 2020

2020 journal article

What is your diagnosis? Abdominal fluid from a dog

Veterinary Clinical Pathology, 49(1), 164–166.

By: A. DiDomenico n, D. Stowe n & A. Lynch n

author keywords: cytology; peritoneal effusion; seminoperitoneum; sperm; vasectomy
MeSH headings : Animals; Ascitic Fluid / diagnostic imaging; Ascitic Fluid / pathology; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Epididymis / diagnostic imaging; Epididymis / pathology; Inflammation / veterinary; Lethargy / veterinary; Male; Photomicrography / veterinary; Spermatocele / diagnostic imaging; Spermatocele / pathology; Spermatocele / veterinary; Spermatozoa / pathology; Testis / diagnostic imaging; Testis / pathology; Ultrasonography / veterinary; Vasectomy / adverse effects; Vasectomy / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 27, 2020

2019 journal article

Acute chlorfenapyr toxicity in 3 dogs from a single household

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 29(6), 686–689.

By: R. Davy*, S. Campos* & A. Lynch n

author keywords: canine; hyperthermia; gastric lavage; pesticide; toxicity
MeSH headings : Animals; Charcoal / therapeutic use; Dog Diseases / chemically induced; Dogs; Fat Emulsions, Intravenous / therapeutic use; Fatal Outcome; Female; Fever / chemically induced; Fever / therapy; Fever / veterinary; Poisoning; Pyrethrins / toxicity
TL;DR: This is the first reported case of chlorfenapyr toxicity in dogs and previous case reports in human medicine have reported a variable mortality rate, although 1 of 3 dogs described here made a complete recovery. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 4, 2019

2019 journal article

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1-Defining populations at risk

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 29(1), 37–48.

By: A. deLaforcade*, L. Bacek*, M. Blais*, R. Goggs*, A. Lynch* & E. Rozanski*

author keywords: cardiomyopathy; IMHA; PLN; thromboembolism; thrombosis
MeSH headings : Animals; Cat Diseases / drug therapy; Cat Diseases / epidemiology; Cat Diseases / etiology; Cats; Critical Care; Delphi Technique; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Fibrinolytic Agents / therapeutic use; Practice Patterns, Physicians' / standards; Risk Factors; Thrombosis / drug therapy; Thrombosis / veterinary; United States / epidemiology; Veterinary Medicine / standards
TL;DR: Documented disease associations with thrombosis provide the basis for recommendations on prescribing provided in subsequent domains, and numerous knowledge gaps were identified. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 20, 2020

2019 journal article

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 3-Defining antithrombotic protocols

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 29(1), 60–74.

By: M. Blais*, D. Bianco, R. Goggs*, A. Lynch n, L. Palmer*, A. Ralph, C. Sharp*

author keywords: administration and dosage; anticoagulant; antiplatelet agents; CURATIVE; veterinary
MeSH headings : Animals; Anticoagulants / therapeutic use; Cat Diseases / drug therapy; Cats; Clinical Protocols / standards; Critical Care; Dog Diseases / drug therapy; Dogs; Fibrinolytic Agents / therapeutic use; Heparin / therapeutic use; Practice Patterns, Physicians' / standards; Veterinary Medicine / standards
TL;DR: Evidence-based recommendations concerning specific protocols could not be formulated for most antithrombotic drugs evaluated, either because of the wide range of dosage reported (eg, aspirin in dogs) or the lack of evidence in the current literature. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 4, 2019

2019 journal article

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 4-Refining and monitoring antithrombotic therapies

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 29(1), 75–87.

By: C. Sharp*, A. deLaforcade*, A. Koenigshof*, A. Lynch n & J. Thomason*

author keywords: anticoagulant; antiplatelet agent; cats; dogs; thromboprophylaxis; therapeutic monitoring
MeSH headings : Animals; Anticoagulants / adverse effects; Anticoagulants / therapeutic use; Cat Diseases / drug therapy; Cats; Critical Care; Dog Diseases / drug therapy; Dogs; Drug Monitoring / veterinary; Fibrinolytic Agents / adverse effects; Fibrinolytic Agents / therapeutic use; Heparin / adverse effects; Heparin / therapeutic use; Practice Patterns, Physicians' / standards; Surveys and Questionnaires; Thrombosis / drug therapy; Thrombosis / veterinary; United States; Veterinary Medicine / standards
TL;DR: Significant knowledge gaps were highlighted in the field, indicating the need for substantial additional research in this field, and the final guidelines recommend that therapeutic monitoring should be performed when using warfarin or unfractionated heparin in dogs and cats at risk of thrombosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 4, 2019

2019 journal article

Retrospective evaluation of Micrurus fulvius (Eastern coral snake) envenomation and the use of mechanical ventilation in dogs and a cat (2011-2016): 8 cases

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 29(6), 662–667.

By: S. Campos*, A. Allen-Durrance*, M. Schaer* & A. Lynch n

author keywords: hypoventilation; environmental toxins; neuromuscular disorders; peripheral nervous system disorders; respiratory failure
MeSH headings : Adaptor Proteins, Signal Transducing; Animals; Antivenins / administration & dosage; Cats; Cell Cycle Proteins; Cohort Studies; Coral Snakes; Dogs; Hospitalization; Hospitals, University; Humans; Male; Medical Records; Positive-Pressure Respiration; Respiration, Artificial / veterinary; Respiratory Insufficiency / etiology; Respiratory Insufficiency / therapy; Respiratory Insufficiency / veterinary; Retrospective Studies; Snake Bites / therapy; Snake Bites / veterinary
TL;DR: Ventilatory failure secondary to Eastern coral snake envenomation necessitating MV carries an excellent prognosis and is better than reported for other causes of lower motor neuron disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 28, 2019

2018 journal article

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

Nature Biomedical Engineering, 2(1), 17–26.

By: J. Tang n, T. Su n, K. Huang n, P. Dinh n, Z. Wang*, A. Vandergriff n, M. Hensley n, J. Cores n ...

TL;DR: The attachment of platelet nanovesicles to the surface of cardiac stem cells increases the retention of the cells delivered to the heart and reduces infarct size in rat and pig models of acute myocardial infarction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Fluid Therapy in Lung Disease

Veterinary Clinics of North America: Small Animal Practice, 47(2), 461–470.

By: E. Rozanski* & A. Lynch*

author keywords: Extravascular lung water; Pulmonary contusion; Pulmonary edema; Pneumonia; Crystalloids
MeSH headings : Animals; Biomarkers; Cat Diseases / diagnostic imaging; Cat Diseases / therapy; Cats; Colloids / therapeutic use; Dog Diseases / diagnostic imaging; Dog Diseases / therapy; Dogs; Fluid Therapy / methods; Fluid Therapy / veterinary; Lung Diseases / diagnostic imaging; Lung Diseases / therapy; Lung Diseases / veterinary
TL;DR: In dogs and cats with preexisting confirmed or suspected pulmonary disease, concerns may exist that the fluid therapy may impair gas exchange, either through increases in hydrostatic pressures or extravasation, so a conservative fluid therapy plan is preferred with close monitoring of its tolerance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: February 21, 2020

2016 journal article

Assessment of hemostatic changes in a model of acute hemorrhage in dogs.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001).

Alex Lynch

author keywords: acute coagulopathy of trauma and shock; platelet function; platelet function testing; viscoelastic monitoring
MeSH headings : Animals; Blood Coagulation Tests / veterinary; Disease Models, Animal; Dog Diseases / diagnosis; Dog Diseases / physiopathology; Dogs; Female; Hemorrhage / diagnosis; Hemorrhage / physiopathology; Hemorrhage / veterinary; Hemostasis; Male; Partial Thromboplastin Time / veterinary; Platelet Count / veterinary; Platelet Function Tests / veterinary; Prospective Studies; Prothrombin Time / veterinary; Thrombelastography / veterinary
TL;DR: Platelet dysfunction occurred following hemorrhage in this model, despite a stable platelet count, and platelet function testing in dogs with naturally occurring hemorrhage warrants further investigation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2015 journal article

Acute tracheal compression in a large breed dog due to a dorsal tracheal membrane abscess.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001).

Alex Lynch

author keywords: tracheal compression; tracheal abscess
MeSH headings : Abscess / complications; Abscess / diagnosis; Abscess / veterinary; Animals; Dog Diseases / diagnosis; Dogs; Male; Streptococcal Infections / complications; Streptococcal Infections / diagnosis; Streptococcal Infections / veterinary; Tracheal Diseases / microbiology; Tracheal Diseases / veterinary
TL;DR: To the authors' knowledge, this represents the first report of an abscess in the dorsal tracheal membrane, diagnosed by endoscopic-guided transtracheal fine needle aspiration, causing clinically relevant acutetracheal obstruction. (via Semantic Scholar)
Source: ORCID
Added: September 27, 2022

2015 journal article

Hospital-acquired Anemia in Critically Ill Dogs and Cats: A Multi-Institutional Study.

Journal of Veterinary Internal Medicine.

Alex Lynch

author keywords: Canine; Clinical pathology; Feline; Hematology; Intensive care; Transfusion medicine
MeSH headings : Anemia / etiology; Anemia / pathology; Anemia / veterinary; Animals; Cat Diseases / blood; Cat Diseases / mortality; Cat Diseases / pathology; Cats; Cohort Studies; Critical Illness; Dog Diseases / blood; Dog Diseases / mortality; Dog Diseases / pathology; Dogs; Hematocrit / veterinary; Hospitals, Animal; Iatrogenic Disease
TL;DR: Hospitalized cats were significantly more likely to develop anemia compared to dogs, but anemic dogs were significantly less likely to survive to discharge, and surgical patients were at higher risk of developing hospital‐acquired anemia. (via Semantic Scholar)
Source: ORCID
Added: September 27, 2022

2015 journal article

Massive haemorrhage associated with inadvertent incision of a suspected carotid artery pseudoaneurysm in a cat.

The Journal of Small Animal Practice.

Alex Lynch

MeSH headings : Aneurysm, False / diagnosis; Aneurysm, False / veterinary; Animals; Carotid Arteries; Cat Diseases / diagnosis; Cats; Diagnosis, Differential; Male; Osteotomy / veterinary; Postoperative Hemorrhage / diagnosis; Postoperative Hemorrhage / veterinary
TL;DR: This case highlights the development of pseudoaneurysm as a potential complication of head and neck surgery, and additionally describes a case of massive transfusion in a cat. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2015 journal article

Transfusion practices for treatment of dogs hospitalized following trauma: 125 cases (2008-2013).

Journal of the American Veterinary Medical Association.

Alex Lynch

MeSH headings : Animals; Blood Transfusion / veterinary; Dog Diseases / therapy; Dogs; Female; Hemorrhage / therapy; Hemorrhage / veterinary; Male; Retrospective Studies; Wounds and Injuries / veterinary
TL;DR: Apparent clinical triggers for the decision to perform blood transfusion in dogs hospitalized following traumatic injury included evidence of shock or worsening anemia on admission and requirement for perioperative hemodynamic optimization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2015 journal article

Transfusion practices for treatment of dogs undergoing splenectomy for splenic masses: 542 cases (2001-2012).

Journal of the American Veterinary Medical Association.

Alex Lynch

MeSH headings : Animals; Blood Transfusion / veterinary; Dog Diseases / surgery; Dogs; Female; Hemorrhage / therapy; Hemorrhage / veterinary; Male; Retrospective Studies; Splenectomy / adverse effects; Splenectomy / veterinary; Splenic Neoplasms / surgery; Splenic Neoplasms / veterinary
TL;DR: Evidence of shock, anemia, and hypocoagulability were apparent triggers for the decision to perform blood transfusion in dogs undergoing splenectomy for splenic masses and were likely attributable to hemoperitoneum and related hypovolemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2014 journal article

Clinical experience of anti-Xa monitoring in critically ill dogs receiving dalteparin.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001).

Alex Lynch

author keywords: anticoagulation; canine; low molecular weight heparin; thromboelastography; canine
MeSH headings : Animals; Anticoagulants / administration & dosage; Critical Illness; Dalteparin / adverse effects; Dalteparin / therapeutic use; Dog Diseases / drug therapy; Dogs; Factor Xa / analysis; Factor Xa / drug effects; Factor Xa Inhibitors / adverse effects; Factor Xa Inhibitors / therapeutic use; Female; Male; Monitoring, Physiologic / methods; Thrombosis / prevention & control; Thrombosis / veterinary
TL;DR: Dalteparin was well tolerated in a heterogeneous population of dogs but dogs that appear more hypercoagulable on pre-treatment TEG may require closer monitoring and greater dose adjustment to achieve the target anti-Xa range. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 27, 2022

2013 journal article

Cytokine and transcription factor expression by Aspergillus fumigatus-stimulated peripheral blood mononuclear cells in dogs with sino-nasal aspergillosis

Veterinary Immunology and Immunopathology, 154(3-4), 111–120.

By: M. Vanherberghen*, F. Bureau*, I. Peters*, M. Day*, A. Lynch*, L. Fievez*, F. Billen*, C. Clercx*, D. Peeters*

author keywords: Dog; Nasal mucosa; Aspergillus fumigatus; Peripheral blood mononuclear cells; Immune response
MeSH headings : Animals; Aspergillosis / immunology; Aspergillosis / microbiology; Aspergillosis / veterinary; Aspergillus fumigatus / physiology; Cell Proliferation; Cytokines / genetics; Cytokines / metabolism; Dog Diseases / immunology; Dog Diseases / microbiology; Dogs; Female; Gene Expression Regulation / immunology; Leukocytes, Mononuclear / immunology; Leukocytes, Mononuclear / metabolism; Male; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: The results suggest that the incapacity of affected dogs to clear these fungal infections is not related to a defect in Th1 immunity or to an overwhelming regulatory reaction, but rather to an uncontrolled pro-inflammatory reaction driven by Th17 cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 29, 2020

2011 journal article

Postoperative haemorrhage associated with active suction drains in two dogs.

The Journal of Small Animal Practice.

Alex Lynch

MeSH headings : Animals; Dog Diseases / surgery; Dogs; Female; Hypovolemia / etiology; Hypovolemia / prevention & control; Hypovolemia / veterinary; Male; Postoperative Hemorrhage / etiology; Postoperative Hemorrhage / prevention & control; Postoperative Hemorrhage / veterinary; Suction / adverse effects; Suction / veterinary
TL;DR: This article describes two dogs in which an active suction drain was placed to manage dead space at the surgical site and acute haemorrhage and hypovolaemia occurred postoperatively and fluid resuscitation and temporary discontinuation of drainage resulted in resolution of clinical signs. (via Semantic Scholar)
Source: ORCID
Added: September 27, 2022

Employment

Updated: February 16th, 2021 17:34

2017 - present

North Carolina State University Raleigh, NC, US
Assistant Professor in Emergency and Critical Care Department of Clinical Sciences

2015 - 2017

University of Florida Gainesville, FL, US
Clinical Assistant Professor Small Animal Clinical Sciences

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.