Aoi Nakanishi-Hester

https://orcid.org/0000-0002-5967-0477

I am a dependable, passionate, and determined DVM/Ph.D. dual degree student studying neuroscience at NC State University College of Veterinary Medicine. One of my career goals is to improve animal and human welfare through translational research as a veterinarian. I study Alzheimer's Disease (AD) in the murine model. My project works as a bridge to fulfill the knowledge gap by defining the molecular mechanism of how protein kinase, known as TAK1, activation causes memory loss.

Works (2)

Updated: July 11th, 2023 21:14
Download BibTeX Download Plain Text View JSON

2023 journal article

Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer?s disease mouse models

JOURNAL OF CELL SCIENCE, 136(6).

By: K. Sai n, A. Nakanishi n, K. Scofield n, D. Tokarz n, K. Linder n, T. Cohen *, J. Ninomiya-Tsuji  n

author keywords: Alzheimer?s disease; Cell death; Inflammation; TAK1
MeSH headings : Animals; Mice; Alzheimer Disease / genetics; Calcium; Cytokines / metabolism; Neuroinflammatory Diseases; Signal Transduction / physiology
Sources: Web Of Science, ORCID
Added: May 30, 2023

2022 journal article

A Pilot, Open-Label Study to Evaluate the Efficacy of Intra-Articular Administration of a Caninized TNF Receptor Fc Fusion Protein as a Treatment for Osteoarthritis-Associated Joint Pain

FRONTIERS IN VETERINARY SCIENCE, 9.

By: A. Nakanishi n, B. Lascelles  n, J. Allen n, B. Case n, D. Gearing* & M. Enomoto n 

author keywords: osteoarthritis; joint pain; TNF-alpha; force plate; limb use asymmetry test
Sources: Web Of Science, ORCID
Added: June 27, 2022

Employment

Updated: April 21st, 2023 14:21

2022 - present

NC State University College of Veterinary Medicine Raleigh, NC, US
Ph.D./DVM student Comparative Biomedical Sciences