Works (39)

Updated: March 1st, 2024 16:18

2023 journal article

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health. METABOLITES, 13(7).

By: E. Krueger*, L. Griffin n, J. Beales*, T. Lloyd*, N. Brown*, W. Elison*, C. Kay n, A. Neilson n, J. Tessem*

co-author countries: United States of America 🇺🇸
author keywords: gut microbiome; phytochemicals; flavanol metabolites; glucose sensitivity; responder analysis; personalized nutrition
Sources: Web Of Science, ORCID
Added: August 14, 2023

2023 article

Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N-oxide by modulating gut microbes

Satheesh Babu, A. K., Petersen, C., Iglesias-Carres, L., Paz, H. A., Wankhade, U. D., Neilson, A. P., & Anandh Babu, P. V. (2023, November 3). BIOFACTORS.

By: A. Satheesh Babu*, C. Petersen*, L. Iglesias-Carres n, H. Paz*, U. Wankhade*, A. Neilson n, P. Anandh Babu*

co-author countries: United States of America 🇺🇸
author keywords: blueberry; chlorogenic acid; gut microbes; strawberry; trimethylamine; trimethylamine N-oxide
Source: Web Of Science
Added: November 27, 2023

2023 journal article

Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 120.

By: L. Iglesias-Carres n, S. Chadwick-Corbin n, M. Sweet n & A. Neilson n

co-author countries: United States of America 🇺🇸
author keywords: Atherosclerosis; Cardiovascular disease; FMO3; Trimethylamine; Trimethylamine N-oxide
Sources: Web Of Science, ORCID
Added: January 2, 2024

2023 article

Gut Microbiota Depletion Using Antibiotics to Investigate Diet-Derived Microbial Metabolites: An Efficient Strategy

Babu, A. K. S., Petersen, C., Paz, H. A., Iglesias-Carres, L., Li, Y., Zhong, Y., … Babu, P. V. A. (2023, December 6). MOLECULAR NUTRITION & FOOD RESEARCH.

By: A. Babu*, C. Petersen*, H. Paz*, L. Iglesias-Carres n, Y. Li*, Y. Zhong, A. Neilson n, U. Wankhade*, P. Babu*

co-author countries: United States of America 🇺🇸
author keywords: antibiotics; diet-derived microbial metabolites; gut microbes; metabolic health; trimethylamine; trimethylamine N-oxide
Source: Web Of Science
Added: December 18, 2023

2023 journal article

In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects

JOURNAL OF FUNCTIONAL FOODS, 107.

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Artichoke; Polyphenols; Antiaging; TMAO; Neuroprotective
Source: Web Of Science
Added: August 28, 2023

2023 journal article

Mechanism of off-color formation in potato chips fried in oil systems containing ascorbic acid as a stabilizer

LWT-FOOD SCIENCE AND TECHNOLOGY, 179.

By: L. Iglesias-Carres n, K. Racine n, S. Chadwick n, C. Nunn n, S. Kalambur*, A. Neilson n, M. Ferruzzi*

co-author countries: United States of America 🇺🇸
author keywords: Amino acid; Maillard reaction; BHT; Rosemary; Carnosic acid; Tocopherol; Moisture; Solubility; Citric acid; Canola oil
Sources: Web Of Science, ORCID
Added: June 12, 2023

2022 article

Bioaccessibility and intestinal cell uptake of carotenoids and chlorophylls differ in powdered spinach by the ingredient form as measured using in vitro gastrointestinal digestion and anaerobic fecal fermentation models

Hayes, M., Mohamedshah, Z., Chadwick-Corbin, S., Hoskin, R., Iorizzo, M., Lila, M. A., … Ferruzzi, M. G. (2022, March 8). FOOD & FUNCTION, Vol. 13.

co-author countries: United States of America 🇺🇸
MeSH headings : Anaerobiosis; Caco-2 Cells; Carotenoids / metabolism; Chlorophyll; Digestion; Fermentation; Health Promotion; Humans; Powders; Spinacia oleracea / metabolism
Sources: Web Of Science, ORCID
Added: March 31, 2022

2022 article

Bioaccessibility, gut microbial metabolism and intestinal transport of phenolics from 100% Concord grape juice and whole grapes are similar in a simulated digestion and fecal fermentation model

Mohamedshah, Z., Hayes, M., Chadwick-Corbin, S., Neilson, A. P., & Ferruzzi, M. G. (2022, March 9). FOOD & FUNCTION, Vol. 3.

By: Z. Mohamedshah n, M. Hayes n, S. Chadwick-Corbin n, A. Neilson n & M. Ferruzzi n

co-author countries: United States of America 🇺🇸
MeSH headings : Caco-2 Cells; Digestion; Fermentation; Fruit / chemistry; Gastrointestinal Microbiome; Humans; Phenols / analysis; Vitis / metabolism
Sources: Web Of Science, ORCID
Added: April 4, 2022

2022 journal article

Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 626, 205–210.

By: K. Racine*, L. Iglesias-Carres, J. Herring, M. Ferruzzi*, C. Kay*, J. Tessem, A. Neilson*

author keywords: BTBR; Ob/ob; Type-2 diabetes; Flavanol; Insulin; Beta cell
MeSH headings : Animals; Cacao; Diabetes Mellitus, Type 2 / drug therapy; Female; Humans; Hyperglycemia; Hyperinsulinism; Male; Mice; Obesity; Pilot Projects; Plant Extracts / pharmacology; Plant Extracts / therapeutic use
Sources: Web Of Science, ORCID
Added: October 17, 2022

2022 journal article

Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 109.

By: D. Weikart, V. Indukuri, K. Racine*, K. Coleman, J. Kovac, D. Cockburn, H. Hopfer, A. Neilson*, J. Lambert*

author keywords: Cocoa; sex differences; roasting; fermentation; obesity; inflammation
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use; Body Weight; Cacao; Chocolate; Diet, High-Fat / adverse effects; Disease Models, Animal; Food Ingredients; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Polyphenols / pharmacology
Source: Web Of Science
Added: October 11, 2022

2022 review

Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome?

[Review of ]. FRONTIERS IN NEUROSCIENCE, 16.

By: C. Cheatham*, D. Nieman*, A. Neilson n & M. Lila n

co-author countries: United States of America 🇺🇸
author keywords: age-related; cognition; neuroprotective; phenolic metabolites; prebiotic flavonoids; exercise; microbiome
Sources: Web Of Science, ORCID
Added: March 28, 2022

2022 journal article

Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 74(1), 194–210.

By: L. Griffin n, S. Kohrt*, A. Rathore n, C. Kay n, M. Grabowska* & A. Neilson n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Chromatography, Liquid; Gastrointestinal Microbiome; Polyphenols / analysis; Rats; Tandem Mass Spectrometry; Urinary Bladder Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: February 10, 2021

2022 article

Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo-in vitro colonic fermentation model

Iglesias-Carres, L., Racine, K. C., & Neilson, A. P. (2022, July 11). FOOD & FUNCTION.

By: L. Iglesias-Carres n, K. Racine n & A. Neilson n

co-author countries: United States of America 🇺🇸
MeSH headings : Atherosclerosis / metabolism; Bacteria / metabolism; Beverages; Chlorogenic Acid; Choline / metabolism; Coffee; Fermentation; Humans; Methylamines / metabolism
Source: Web Of Science
Added: July 26, 2022

2022 journal article

Potential of Phenolic Compounds and Their Gut Microbiota-Derived Metabolites to Reduce TMA Formation: Application of an In Vitro Fermentation High-Throughput Screening Model

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(10), 3207–3218.

By: L. Iglesias-Carres n, E. Krueger*, J. Herring, J. Tessem* & A. Neilson n

co-author countries: United States of America 🇺🇸
author keywords: atherosclerosis; food bioactives; gut microbiota metabolites; phenolic compounds; TMA
MeSH headings : Choline / metabolism; Fermentation; Gastrointestinal Microbiome; High-Throughput Screening Assays; Humans; Methylamines
Source: Web Of Science
Added: April 18, 2022

2021 journal article

An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

SCIENTIFIC REPORTS, 11(1).

By: M. Virdee*, N. Saini*, C. Kay n, A. Neilson n, S. Kwan*, K. Helfrich*, S. Mooney*, S. Smith*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Disease Models, Animal; Female; Fetal Alcohol Spectrum Disorders / blood; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / microbiology; Gastrointestinal Microbiome; Male; Mice; Mothers; Pregnancy
Sources: Web Of Science, ORCID
Added: February 10, 2021

2021 journal article

Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 87.

By: L. Griffin n, L. Essenmacher*, K. Racine n, L. Iglesias-Carres n, J. Tessem*, S. Smith*, A. Neilson n

co-author countries: United States of America 🇺🇸
author keywords: Natural products; Genetic diversity; Diabetes; Flavonoids; Personalized nutrition; Interindividual variation
MeSH headings : Animals; Anti-Obesity Agents / therapeutic use; Collaborative Cross Mice / genetics; Collaborative Cross Mice / physiology; Diet, High-Fat / adverse effects; Disease Models, Animal; Female; Genetic Variation; Male; Obesity / drug therapy; Obesity / etiology; Obesity / genetics; Quercetin / therapeutic use; Sex Factors
Source: Web Of Science
Added: January 11, 2021

2021 journal article

Fasting and postprandial trimethylamine N-oxide in sedentary and endurance-trained males following a short-term high-fat diet

PHYSIOLOGICAL REPORTS, 9(16).

By: C. Steele*, M. Baugh*, L. Griffin n, A. Neilson n, B. Davy*, M. Hulver*, K. Davy*

co-author countries: United States of America 🇺🇸
author keywords: endurance-trained; high-fat diet; sedentary; trimethylamine N-oxide
MeSH headings : Adolescent; Adult; Cardiometabolic Risk Factors; Diet, High-Fat / adverse effects; Dietary Fats / metabolism; Endurance Training; Fasting / metabolism; Humans; Male; Methylamines / blood; Postprandial Period; Sedentary Behavior
Source: Web Of Science
Added: September 7, 2021

2021 journal article

Gut Metabolite Trimethylamine N-Oxide Protects INS-1 beta-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions

BIOMOLECULES, 11(12).

By: E. Krueger*, J. Beales*, K. Russon*, W. Elison*, J. Davis*, J. Hansen*, A. Neilson n, J. Hansen, J. Tessem*

co-author countries: United States of America 🇺🇸
author keywords: beta cell; islet; glucolipotoxicity (GLT); glucose stimulated insulin secretion (GSIS); unfolded protein response (UPR); type 2 diabetes (T2D)
MeSH headings : Animals; Cell Proliferation / drug effects; Cell Survival / drug effects; Cells, Cultured; Diabetes Mellitus, Type 2 / metabolism; Diabetes Mellitus, Type 2 / prevention & control; Endoplasmic Reticulum Stress; Endoribonucleases / metabolism; Female; Gastrointestinal Microbiome; Gene Expression Regulation / drug effects; Insulin / metabolism; Insulin-Secreting Cells / cytology; Insulin-Secreting Cells / drug effects; Insulin-Secreting Cells / metabolism; Methylamines / pharmacology; Models, Biological; Multienzyme Complexes / metabolism; Oxidative Stress; Primary Cell Culture; Protein Serine-Threonine Kinases / metabolism; Rats
Source: Web Of Science
Added: January 10, 2022

2021 journal article

Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans

HYPERTENSION, 78(2), 499–511.

By: V. Brunt*, A. Casso*, R. Gioscia-Ryan*, Z. Sapinsley*, B. Ziemba*, Z. Clayton*, A. Bazzoni*, N. VanDongen* ...

co-author countries: United States of America 🇺🇸
author keywords: advanced glycation end products; arterial stiffness; gut microbiota; pulse wave velocity
MeSH headings : Adolescent; Adult; Age Factors; Aged; Aging / blood; Animals; Aorta / drug effects; Aorta / physiology; Blood Pressure / drug effects; Blood Pressure / physiology; Female; Humans; Male; Methylamines / administration & dosage; Methylamines / blood; Mice; Middle Aged; Pulse Wave Analysis; Vascular Stiffness / drug effects; Vascular Stiffness / physiology; Young Adult
Source: Web Of Science
Added: July 19, 2021

2021 article

Journal of Nutritional Biochemistry Special Issue: Polyphenols, obesity, and cardiometabolic health

Bruno, R. S., Neilson, A. P., Lambert, J. D., & Moustaid-Moussa, N. (2021, March). JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Vol. 89.

co-author countries: United States of America 🇺🇸
MeSH headings : Cardiovascular Diseases / prevention & control; Gastrointestinal Microbiome / drug effects; Humans; Obesity / prevention & control; Obesity / therapy; Polyphenols / administration & dosage; Polyphenols / metabolism; Risk Factors; Tea / chemistry
Source: Web Of Science
Added: April 12, 2021

2021 journal article

Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial

NUTRIENTS, 13(9).

By: C. Mitchell*, B. Davy*, M. Ponder*, R. McMillan*, M. Hughes*, M. Hulver*, A. Neilson n, K. Davy*

co-author countries: United States of America 🇺🇸
author keywords: dietary fiber; prebiotics; inulin; diabetes; metabolism; gut microbiota
MeSH headings : Diabetes Mellitus, Type 2 / prevention & control; Dietary Supplements; Female; Humans; Insulin / blood; Insulin Resistance; Inulin / administration & dosage; Inulin / pharmacology; Male; Middle Aged; Pilot Projects; Prebiotics
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Techno-economic analysis of a grape pomace biorefinery: Production of seed oil, polyphenols, and biochar

FOOD AND BIOPRODUCTS PROCESSING, 127, 139–151.

By: Q. Jin*, . Sean F. O'Keefe*, A. Stewart*, A. Neilson n, Y. Kim* & H. Huang*

co-author countries: United States of America 🇺🇸
author keywords: Techno-economic analysis; Grape pomace; Seed oil; Polyphenol; Biochar
Source: Web Of Science
Added: June 10, 2021

2021 journal article

The gut microbiome-derived metabolite trimethylamineN-oxide modulates neuroinflammation and cognitive function with aging

GEROSCIENCE, 43(1), 377–394.

By: V. Brunt*, T. LaRocca*, A. Bazzoni*, Z. Sapinsley*, J. Miyamoto-Ditmon*, R. Gioscia-Ryan*, A. Neilson n, C. Link*, D. Seals*

co-author countries: United States of America 🇺🇸
author keywords: Cognitive impairment; Inflammation; Astrocyte activation; Brain; Memory
MeSH headings : Aging; Animals; Cognition; Gastrointestinal Microbiome; Methylamines; Mice
Source: Web Of Science
Added: September 14, 2020

2021 journal article

Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 91.

By: L. Iglesias-Carres n, M. Hughes*, C. Steele*, M. Ponder*, K. Davy* & A. Neilson n

co-author countries: United States of America 🇺🇸
author keywords: Atherosclerosis; Cardiovasculardisease; Phytochemicals; TMAO
MeSH headings : Animals; Atherosclerosis / metabolism; Atherosclerosis / therapy; Cardiovascular Diseases / metabolism; Cardiovascular Diseases / therapy; Drug Discovery; Gastrointestinal Microbiome / drug effects; Humans; Lipid Metabolism / drug effects; Methylamines / antagonists & inhibitors; Methylamines / metabolism; Oxidative Stress / drug effects; Phytochemicals / pharmacology
Source: Web Of Science
Added: April 26, 2021

2021 article

Utilizing preclinical models of genetic diversity to improve translation of phytochemical activities from rodents to humans and inform personalized nutrition

Iglesias-Carres, L., & Neilson, A. P. (2021, October 14). FOOD & FUNCTION.

By: L. Iglesias-Carres n & A. Neilson n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Genetic Variation / genetics; Humans; Mice; Mice, Inbred Strains / genetics; Nutritional Physiological Phenomena / drug effects; Nutritional Physiological Phenomena / genetics; Phytochemicals / administration & dosage; Phytochemicals / pharmacology; Translational Research, Biomedical
Source: Web Of Science
Added: November 8, 2021

2020 journal article

Flavone Hispidulin Stimulates Glucagon-Like Peptide-1 Secretion and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetic Mice

MOLECULAR NUTRITION & FOOD RESEARCH, 64(6).

By: Y. Wang*, A. Wang*, H. Alkhalidy*, J. Luo*, E. Moomaw*, A. Neilson n, D. Liu*

co-author countries: China 🇨🇳 Jordan 🇯🇴 United States of America 🇺🇸
author keywords: diabetes; glucagon-like peptide-1; hispidulin; insulin; mice
MeSH headings : Animals; Cell Line; Cell Survival / drug effects; Cyclic AMP / metabolism; Cyclic AMP-Dependent Protein Kinases / metabolism; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Eating / drug effects; Flavones / pharmacology; Glucagon-Like Peptide 1 / metabolism; Hyperglycemia / drug therapy; Hyperglycemia / metabolism; Hypoglycemic Agents / pharmacology; Insulin / metabolism; Insulin-Secreting Cells / drug effects; Insulin-Secreting Cells / metabolism; Male; Mice, Inbred C57BL
Source: Web Of Science
Added: February 17, 2020

2020 journal article

Grape pomace and its secondary waste management: Biochar production for a broad range of lead (Pb) removal from water

ENVIRONMENTAL RESEARCH, 186.

By: Q. Jin*, Z. Wang*, Y. Feng*, Y. Kim*, A. Stewart*, . Sean F. O'Keefe*, A. Neilson n, Z. He*, H. Huang*

co-author countries: United States of America 🇺🇸
author keywords: Grape pomace; Biochar; Pb; Adsorption mechanism; Water contamination
MeSH headings : Adsorption; Charcoal; Lead; Vitis; Wastewater; Water
Source: Web Of Science
Added: August 3, 2020

2020 journal article

Modulating Phenolic Bioaccessibility and Glycemic Response of Starch-Based Foods in Wistar Rats by Physical Complexation between Starch and Phenolic Acid

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(46), 13257–13266.

By: M. Li n, L. Griffin n, S. Corbin n, A. Neilson n & M. Ferruzzi n

co-author countries: United States of America 🇺🇸
author keywords: LC-MS; in vitro bioaccessibility; cellular uptake efficiency; postprandial glycemic response; Caco-2 human intestinal cells; starch-phenolic complexes
MeSH headings : Animals; Blood Glucose / metabolism; Caco-2 Cells; Glycemic Index; Humans; Hydroxybenzoates / metabolism; Intestines; Male; Phenols / metabolism; Rats; Rats, Wistar; Solanum tuberosum / metabolism; Starch / analysis; Starch / metabolism; Zea mays / metabolism
Source: Web Of Science
Added: January 4, 2021

2020 journal article

Postprandial skeletal muscle metabolism following a high-fat diet in sedentary and endurance-trained males

JOURNAL OF APPLIED PHYSIOLOGY, 128(4), 872–883.

By: M. Baugh*, S. Bowser*, R. McMillan*, B. Davy*, L. Essenmacher*, A. Neilson n, M. Hulver*, K. Davy*

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: exercise; high-fat diet; metabolic flexibility; skeletal muscle; substrate oxidation
MeSH headings : Diet, High-Fat; Endurance Training; Fasting; Humans; Male; Muscle, Skeletal; Postprandial Period
Source: Web Of Science
Added: May 18, 2020

2020 journal article

Preference for and sensitivity to flavanol mean degree of polymerization in model wines is correlated with body composition

APPETITE, 144.

By: L. Griffin n, C. Diako*, L. Miller*, A. Neilson n, C. Ross* & A. Stewart*

co-author countries: United States of America 🇺🇸
author keywords: Astringency; Preference; BMI; Body fat percentage; PROP
MeSH headings : Adipose Tissue; Adult; Body Composition / physiology; Body Mass Index; Body Weight / physiology; Female; Food Preferences / drug effects; Food Preferences / physiology; Humans; Male; Middle Aged; Polymerization; Polyphenols / administration & dosage; Propylthiouracil / administration & dosage; Taste / drug effects; Taste / physiology; Taste Buds / drug effects; Taste Threshold / drug effects; Wine / analysis; Young Adult
Sources: Web Of Science, ORCID
Added: December 9, 2019

2020 journal article

Serum endotoxin, gut permeability and skeletal muscle metabolic adaptations following a short term high fat diet in humans

METABOLISM-CLINICAL AND EXPERIMENTAL, 103.

By: S. Bowser*, R. McMillan*, N. Boutagy*, M. Tarpey*, A. Smithson*, K. Osterberg*, A. Neilson*, B. Davy*, K. Davy*, M. Hulver*

co-author countries: United States of America 🇺🇸
author keywords: Skeletal muscle; Substrate oxidation; Metabolic flexibility; High fat diet; Metabolic adaptation
MeSH headings : Adaptation, Physiological / physiology; Adult; Diet, High-Fat; Dietary Fats / pharmacology; Endotoxins / blood; Energy Metabolism / drug effects; Humans; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Intestines / drug effects; Intestines / pathology; Lipid Metabolism / drug effects; Male; Muscle, Skeletal / drug effects; Muscle, Skeletal / metabolism; Muscle, Skeletal / pathology; Permeability; Young Adult
Source: Web Of Science
Added: February 27, 2020

2020 article

Supplemental treatment options for diabetes: how flavanol metabolites improve beta-cell function

Lloyd, T., Griffin, L., Krueger, E., Beales, J., Barlow, A., Sheets, J., … Tessem, J. (2020, April). FASEB JOURNAL, Vol. 34.

By: T. Lloyd*, L. Griffin n, E. Krueger*, J. Beales*, A. Barlow*, J. Sheets*, I. Ekpo*, M. Ross* ...

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 journal article

Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans

HYPERTENSION, 76(1), 101–112.

By: V. Brunt*, R. Gioscia-Ryan*, A. Casso*, N. VanDongen*, B. Ziemba*, Z. Sapinsley*, J. Richey*, M. Zigler* ...

co-author countries: United States of America 🇺🇸
author keywords: acetylcholine; aging; brachial artery; microbiota nitric oxide; superoxide
MeSH headings : Acetylcholine / pharmacology; Adolescent; Adult; Aged; Aging / blood; Aging / physiology; Animals; Antioxidants / pharmacology; Ascorbic Acid / pharmacology; Brachial Artery / drug effects; Brachial Artery / physiology; Carotid Arteries / drug effects; Carotid Arteries / physiology; Cyclic N-Oxides / pharmacology; Dietary Supplements; Endothelium, Vascular / drug effects; Gastrointestinal Microbiome; Humans; Methylamines / administration & dosage; Methylamines / blood; Methylamines / toxicity; Mice; Mice, Inbred C57BL; Middle Aged; Nitric Oxide / blood; Nitric Oxide Synthase Type III / metabolism; Oxidative Stress / drug effects; Spin Labels; Superoxides / metabolism; Tyrosine / analogs & derivatives; Tyrosine / blood; Vasodilation / drug effects; Vasodilation / physiology; Young Adult
Source: Web Of Science
Added: July 27, 2020

2019 journal article

A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer

FOOD & FUNCTION, 10(4), 2138–2147.

By: L. Griffin*, Z. Djuric*, C. Angiletta*, C. Mitchell*, M. Baugh*, K. Davy*, A. Neilson*

co-author countries: United States of America 🇺🇸
MeSH headings : Adult; Aged; Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Bacteria / metabolism; Betaine / blood; Choline / blood; Colonic Neoplasms / blood; Colonic Neoplasms / diet therapy; Colonic Neoplasms / metabolism; Colonic Neoplasms / microbiology; Diet, Mediterranean; Fasting; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines / blood; Middle Aged
Source: Web Of Science
Added: April 20, 2020

2019 journal article

Comparison of Common Analytical Methods for the Quantification of Total Polyphenols and Flavanols in Fruit Juices and Ciders

JOURNAL OF FOOD SCIENCE, 84(8), 2147–2158.

By: S. Ma*, C. Kim*, A. Neilson n, L. Griffin n, G. Peck*, . Sean F. O'Keefe*, A. Stewart*

co-author countries: United States of America 🇺🇸
author keywords: BSA precipitation; DMAC; flavanols; Folin-Ciocalteu; Lowenthal permanganate titration
MeSH headings : Flavanones / analysis; Food Analysis / methods; Fruit / chemistry; Fruit and Vegetable Juices / analysis; Malus / chemistry; Polyphenols / analysis
Sources: Web Of Science, ORCID
Added: August 5, 2019

2019 journal article

Compositional Characterization of Different Industrial White and Red Grape Pomaces in Virginia and the Potential Valorization of the Major Components

FOODS, 8(12).

By: Q. Jin*, J. O'Hair*, A. Stewart*, . Sean F. O'Keefe*, A. Neilson n, Y. Kim*, M. McGuire, A. Lee*, G. Wilder*, H. Huang*

co-author countries: United States of America 🇺🇸
author keywords: grape pomace; chemical composition; fatty acids; polyphenols; carbohydrates; lignin
Source: Web Of Science
Added: January 27, 2020

2019 journal article

Development of a rapid ultra performance hydrophilic interaction liquid chromatography tandem mass spectrometry method for procyanidins with enhanced ionization efficiency

JOURNAL OF CHROMATOGRAPHY A, 1594, 54–64.

By: K. Racine*, A. Lee*, A. Stewart*, K. Blakeslee* & A. Neilson n

co-author countries: United States of America 🇺🇸
author keywords: Cocoa; Sensitivity; Electrospray ionization; Diol; Ammonium formate
MeSH headings : Biflavonoids / analysis; Biflavonoids / isolation & purification; Catechin / analysis; Catechin / isolation & purification; Chemistry Techniques, Analytical / methods; Chromatography, Liquid; Formates / chemistry; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Proanthocyanidins / analysis; Proanthocyanidins / isolation & purification; Tandem Mass Spectrometry
Source: Web Of Science
Added: May 28, 2019

2019 journal article

Flavanol Polymerization Is a Superior Predictor of alpha-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans

ANTIOXIDANTS, 8(12).

co-author countries: United States of America 🇺🇸
author keywords: flavan-3-ol; procyanidin; alpha-glucosidase; melanoidin; Maillard reaction
Source: Web Of Science
Added: January 27, 2020

2019 journal article

Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet

NUTRITION RESEARCH, 66, 32–47.

By: L. Griffin*, D. Fausnacht*, J. Tuzo*, A. Addington*, K. Racine*, H. Zhang*, M. Hughes*, K. England* ...

co-author countries: United States of America 🇺🇸
author keywords: Mean degree of polymerization (mDP); Flavanols; Procyanidins (PCs); Glucose intolerance; Cytokines
MeSH headings : Adipose Tissue / chemistry; Animals; Body Composition / drug effects; Diet, High-Fat / adverse effects; Dietary Supplements; Eating / drug effects; Flavonols / administration & dosage; Glucose Intolerance / prevention & control; Grape Seed Extract / chemistry; Inflammation / prevention & control; Insulin Resistance; Interleukin-6 / analysis; Male; Mice; Mice, Inbred C57BL; Obesity / physiopathology; Pinus / chemistry; Plant Bark / chemistry; Weight Gain / drug effects
Source: Web Of Science
Added: July 22, 2019

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