Works (33)

Updated: April 11th, 2023 10:13

2022 article

Bioaccessibility and intestinal cell uptake of carotenoids and chlorophylls differ in powdered spinach by the ingredient form as measured using in vitro gastrointestinal digestion and anaerobic fecal fermentation models

Hayes, M., Mohamedshah, Z., Chadwick-Corbin, S., Hoskin, R., Iorizzo, M., Lila, M. A., … Ferruzzi, M. G. (2022, March 8). FOOD & FUNCTION, Vol. 13.

By: M. Hayes, Z. Mohamedshah, S. Chadwick-Corbin, R. Hoskin, M. Iorizzo, M. Lila, A. Neilson, M. Ferruzzi

Sources: Web Of Science, ORCID
Added: March 31, 2022

2022 article

Bioaccessibility, gut microbial metabolism and intestinal transport of phenolics from 100% Concord grape juice and whole grapes are similar in a simulated digestion and fecal fermentation model

Mohamedshah, Z., Hayes, M., Chadwick-Corbin, S., Neilson, A. P., & Ferruzzi, M. G. (2022, March 9). FOOD & FUNCTION, Vol. 3.

Sources: Web Of Science, ORCID
Added: April 4, 2022

2022 journal article

Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 626, 205–210.

By: K. Racine, L. Iglesias-Carres, J. Herring, M. Ferruzzi, C. Kay, J. Tessem, A. Neilson

author keywords: BTBR; Ob/ob; Type-2 diabetes; Flavanol; Insulin; Beta cell
Sources: Web Of Science, ORCID
Added: October 17, 2022

2022 journal article

Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 109.

By: D. Weikart, V. Indukuri, K. Racine, K. Coleman, J. Kovac, D. Cockburn, H. Hopfer, A. Neilson, J. Lambert

author keywords: Cocoa; sex differences; roasting; fermentation; obesity; inflammation
Source: Web Of Science
Added: October 11, 2022

2022 review

Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome?

[Review of ]. FRONTIERS IN NEUROSCIENCE, 16.

By: C. Cheatham*, D. Nieman, A. Neilson & M. Lila

author keywords: age-related; cognition; neuroprotective; phenolic metabolites; prebiotic flavonoids; exercise; microbiome
Sources: Web Of Science, ORCID
Added: March 28, 2022

2022 journal article

Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 74(1), 194–210.

By: L. Griffin, S. Kohrt*, A. Rathore, C. Kay, M. Grabowska* & A. Neilson

Sources: Web Of Science, ORCID
Added: February 10, 2021

2022 article

Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo-in vitro colonic fermentation model

Iglesias-Carres, L., Racine, K. C., & Neilson, A. P. (2022, July 11). FOOD & FUNCTION.

By: L. Iglesias-Carres, K. Racine & A. Neilson

Source: Web Of Science
Added: July 26, 2022

2022 journal article

Potential of Phenolic Compounds and Their Gut Microbiota-Derived Metabolites to Reduce TMA Formation: Application of an In Vitro Fermentation High-Throughput Screening Model

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(10), 3207–3218.

By: L. Iglesias-Carres, E. Krueger*, J. Herring*, J. Tessem* & A. Neilson

author keywords: atherosclerosis; food bioactives; gut microbiota metabolites; phenolic compounds; TMA
Source: Web Of Science
Added: April 18, 2022

2021 journal article

An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

SCIENTIFIC REPORTS, 11(1).

By: M. Virdee*, N. Saini*, C. Kay, A. Neilson, S. Kwan*, K. Helfrich*, S. Mooney*, S. Smith*

Sources: Web Of Science, ORCID
Added: February 10, 2021

2021 journal article

Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 87.

By: L. Griffin, L. Essenmacher*, K. Racine, L. Iglesias-Carres, J. Tessem*, S. Smith*, A. Neilson

author keywords: Natural products; Genetic diversity; Diabetes; Flavonoids; Personalized nutrition; Interindividual variation
Source: Web Of Science
Added: January 11, 2021

2021 journal article

Fasting and postprandial trimethylamine N-oxide in sedentary and endurance-trained males following a short-term high-fat diet

PHYSIOLOGICAL REPORTS, 9(16).

By: C. Steele*, M. Baugh*, L. Griffin, A. Neilson, B. Davy*, M. Hulver*, K. Davy*

author keywords: endurance-trained; high-fat diet; sedentary; trimethylamine N-oxide
Source: Web Of Science
Added: September 7, 2021

2021 journal article

Gut Metabolite Trimethylamine N-Oxide Protects INS-1 beta-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions

BIOMOLECULES, 11(12).

By: E. Krueger*, J. Beales*, K. Russon*, W. Elison*, J. Davis*, J. Hansen*, A. Neilson, J. Hansen, J. Tessem*

author keywords: beta cell; islet; glucolipotoxicity (GLT); glucose stimulated insulin secretion (GSIS); unfolded protein response (UPR); type 2 diabetes (T2D)
Source: Web Of Science
Added: January 10, 2022

2021 journal article

Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans

HYPERTENSION, 78(2), 499–511.

By: V. Brunt*, A. Casso*, R. Gioscia-Ryan*, Z. Sapinsley*, B. Ziemba*, Z. Clayton*, A. Bazzoni*, N. VanDongen* ...

author keywords: advanced glycation end products; arterial stiffness; gut microbiota; pulse wave velocity
Source: Web Of Science
Added: July 19, 2021

2021 article

Journal of Nutritional Biochemistry Special Issue: Polyphenols, obesity, and cardiometabolic health

Bruno, R. S., Neilson, A. P., Lambert, J. D., & Moustaid-Moussa, N. (2021, March). JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Vol. 89.

By: R. Bruno*, A. Neilson, J. Lambert* & N. Moustaid-Moussa*

Source: Web Of Science
Added: April 12, 2021

2021 journal article

Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial

NUTRIENTS, 13(9).

By: C. Mitchell*, B. Davy*, M. Ponder*, R. McMillan*, M. Hughes*, M. Hulver*, A. Neilson, K. Davy*

author keywords: dietary fiber; prebiotics; inulin; diabetes; metabolism; gut microbiota
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Techno-economic analysis of a grape pomace biorefinery: Production of seed oil, polyphenols, and biochar

FOOD AND BIOPRODUCTS PROCESSING, 127, 139–151.

By: Q. Jin*, . Sean F. O'Keefe*, A. Stewart*, A. Neilson, Y. Kim* & H. Huang*

author keywords: Techno-economic analysis; Grape pomace; Seed oil; Polyphenol; Biochar
Source: Web Of Science
Added: June 10, 2021

2021 journal article

The gut microbiome-derived metabolite trimethylamineN-oxide modulates neuroinflammation and cognitive function with aging

GEROSCIENCE, 43(1), 377–394.

By: V. Brunt*, T. LaRocca*, A. Bazzoni*, Z. Sapinsley*, J. Miyamoto-Ditmon*, R. Gioscia-Ryan*, A. Neilson, C. Link*, D. Seals*

author keywords: Cognitive impairment; Inflammation; Astrocyte activation; Brain; Memory
Source: Web Of Science
Added: September 14, 2020

2021 journal article

Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 91.

By: L. Iglesias-Carres, M. Hughes*, C. Steele*, M. Ponder*, K. Davy* & A. Neilson

author keywords: Atherosclerosis; Cardiovasculardisease; Phytochemicals; TMAO
Source: Web Of Science
Added: April 26, 2021

2021 article

Utilizing preclinical models of genetic diversity to improve translation of phytochemical activities from rodents to humans and inform personalized nutrition

Iglesias-Carres, L., & Neilson, A. P. (2021, October 14). FOOD & FUNCTION.

By: L. Iglesias-Carres & A. Neilson

Source: Web Of Science
Added: November 8, 2021

2020 journal article

Flavone Hispidulin Stimulates Glucagon-Like Peptide-1 Secretion and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetic Mice

MOLECULAR NUTRITION & FOOD RESEARCH, 64(6).

By: Y. Wang*, A. Wang*, H. Alkhalidy*, J. Luo*, E. Moomaw*, A. Neilson, D. Liu*

author keywords: diabetes; glucagon-like peptide-1; hispidulin; insulin; mice
Source: Web Of Science
Added: February 17, 2020

2020 journal article

Grape pomace and its secondary waste management: Biochar production for a broad range of lead (Pb) removal from water

ENVIRONMENTAL RESEARCH, 186.

By: Q. Jin*, Z. Wang*, Y. Feng*, Y. Kim*, A. Stewart*, . Sean F. O'Keefe*, A. Neilson, Z. He*, H. Huang*

author keywords: Grape pomace; Biochar; Pb; Adsorption mechanism; Water contamination
Source: Web Of Science
Added: August 3, 2020

2020 journal article

Modulating Phenolic Bioaccessibility and Glycemic Response of Starch-Based Foods in Wistar Rats by Physical Complexation between Starch and Phenolic Acid

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(46), 13257–13266.

By: M. Li, L. Griffin, S. Corbin n, A. Neilson & M. Ferruzzi

author keywords: LC-MS; in vitro bioaccessibility; cellular uptake efficiency; postprandial glycemic response; Caco-2 human intestinal cells; starch-phenolic complexes
Source: Web Of Science
Added: January 4, 2021

2020 journal article

Postprandial skeletal muscle metabolism following a high-fat diet in sedentary and endurance-trained males

JOURNAL OF APPLIED PHYSIOLOGY, 128(4), 872–883.

By: M. Baugh*, S. Bowser*, R. McMillan*, B. Davy*, L. Essenmacher*, A. Neilson, M. Hulver*, K. Davy*

author keywords: exercise; high-fat diet; metabolic flexibility; skeletal muscle; substrate oxidation
Source: Web Of Science
Added: May 18, 2020

2020 journal article

Preference for and sensitivity to flavanol mean degree of polymerization in model wines is correlated with body composition

APPETITE, 144.

By: L. Griffin, C. Diako*, L. Miller*, A. Neilson, C. Ross* & A. Stewart

author keywords: Astringency; Preference; BMI; Body fat percentage; PROP
Sources: Web Of Science, ORCID
Added: December 9, 2019

2020 journal article

Serum endotoxin, gut permeability and skeletal muscle metabolic adaptations following a short term high fat diet in humans

METABOLISM-CLINICAL AND EXPERIMENTAL, 103.

By: S. Bowser*, R. McMillan*, N. Boutagy*, M. Tarpey*, A. Smithson*, K. Osterberg*, A. Neilson, B. Davy*, K. Davy*, M. Hulver*

author keywords: Skeletal muscle; Substrate oxidation; Metabolic flexibility; High fat diet; Metabolic adaptation
Source: Web Of Science
Added: February 27, 2020

2020 article

Supplemental treatment options for diabetes: how flavanol metabolites improve beta-cell function

Lloyd, T., Griffin, L., Krueger, E., Beales, J., Barlow, A., Sheets, J., … Tessem, J. (2020, April). FASEB JOURNAL, Vol. 34.

By: T. Lloyd*, L. Griffin, E. Krueger*, J. Beales*, A. Barlow*, J. Sheets*, I. Ekpo*, M. Ross* ...

Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 journal article

Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans

HYPERTENSION, 76(1), 101–112.

By: V. Brunt*, R. Gioscia-Ryan*, A. Casso*, N. VanDongen*, B. Ziemba*, Z. Sapinsley*, J. Richey*, M. Zigler* ...

author keywords: acetylcholine; aging; brachial artery; microbiota nitric oxide; superoxide
Source: Web Of Science
Added: July 27, 2020

2019 journal article

A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer

FOOD & FUNCTION, 10(4), 2138–2147.

By: L. Griffin, Z. Djuric*, C. Angiletta*, C. Mitchell*, M. Baugh*, K. Davy*, A. Neilson

Source: Web Of Science
Added: April 20, 2020

2019 journal article

Comparison of Common Analytical Methods for the Quantification of Total Polyphenols and Flavanols in Fruit Juices and Ciders

JOURNAL OF FOOD SCIENCE, 84(8), 2147–2158.

By: S. Ma*, C. Kim*, A. Neilson, L. Griffin, G. Peck*, . Sean F. O'Keefe*, A. Stewart

author keywords: BSA precipitation; DMAC; flavanols; Folin-Ciocalteu; Lowenthal permanganate titration
Sources: Web Of Science, ORCID
Added: August 5, 2019

2019 journal article

Compositional Characterization of Different Industrial White and Red Grape Pomaces in Virginia and the Potential Valorization of the Major Components

FOODS, 8(12).

By: Q. Jin*, J. O'Hair*, A. Stewart*, . Sean F. O'Keefe*, A. Neilson, Y. Kim*, M. McGuire*, A. Lee*, G. Wilder*, H. Huang*

author keywords: grape pomace; chemical composition; fatty acids; polyphenols; carbohydrates; lignin
Source: Web Of Science
Added: January 27, 2020

2019 journal article

Development of a rapid ultra performance hydrophilic interaction liquid chromatography tandem mass spectrometry method for procyanidins with enhanced ionization efficiency

JOURNAL OF CHROMATOGRAPHY A, 1594, 54–64.

By: K. Racine, A. Lee*, A. Stewart*, K. Blakeslee* & A. Neilson

author keywords: Cocoa; Sensitivity; Electrospray ionization; Diol; Ammonium formate
Source: Web Of Science
Added: May 28, 2019

2019 journal article

Flavanol Polymerization Is a Superior Predictor of alpha-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans

ANTIOXIDANTS, 8(12).

By: K. Racine, B. Wiersema*, L. Griffin, L. Essenmacher*, A. Lee*, H. Hopfer*, J. Lambert*, A. Stewart*, A. Neilson

author keywords: flavan-3-ol; procyanidin; alpha-glucosidase; melanoidin; Maillard reaction
Source: Web Of Science
Added: January 27, 2020

2019 journal article

Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet

NUTRITION RESEARCH, 66, 32–47.

By: L. Griffin, D. Fausnacht*, J. Tuzo*, A. Addington*, K. Racine, H. Zhang*, M. Hughes*, K. England* ...

author keywords: Mean degree of polymerization (mDP); Flavanols; Procyanidins (PCs); Glucose intolerance; Cytokines
Source: Web Of Science
Added: July 22, 2019