Alena Joignant

College of Sciences

Works (8)

Updated: November 28th, 2024 05:01

2024 article

Obtaining 20 μm Spatial Resolution with a 2940 nm Laser by IR-MALDESI Mass Spectrometry Imaging

Eisenberg, S. M., Joignant, A. N., Knizner, K. T., Manni, J. G., & Muddiman, D. C. (2024, November 8). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 11.

By: S. Eisenberg n, A. Joignant n, K. Knizner n, J. Manni & D. Muddiman n

author keywords: IR-MALDESI; mass spectrometry imaging; mid-IRlaser; spatial resolution
Sources: Web Of Science, NC State University Libraries
Added: November 18, 2024

2024 article

Quantitative sampling by IR-MALDESI is not susceptible to tissue heterogeneity in a multi-organ model

Joignant, A. N., Hector, E. C., Barnes, M. M., Kullman, S. W., & Muddiman, D. C. (2024, November 13). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 11.

By: A. Joignant n, E. Hector n, M. Barnes n, S. Kullman n & D. Muddiman n

author keywords: IR-MALDESI; Mass spectrometry imaging; Quantitative; Zebrafish
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 25, 2024

2023 journal article

Evaluating the optimal tissue thickness for mass spectrometry imaging using infrared matrix-assisted laser desorption electrospray ionization

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 37(22).

By: A. Joignant n, K. Knizner n, Y. Xi n & D. Muddiman n

TL;DR: This work defines an optimal sample thickness for IR-MALDESI-MSI and demonstrates the utility of optimizing tissue thickness for MSI platforms of comparable Z resolution. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 30, 2023

2023 article

Impact of wavelength and spot size on laser depth of focus: Considerations for mass spectrometry imaging of non-flat samples

Joignant, A. N. N., Xi, Y., & Muddiman, D. C. C. (2023, March 14). JOURNAL OF MASS SPECTROMETRY, Vol. 3.

By: A. Joignant n, Y. Xi n & D. Muddiman n

author keywords: depth of focus; laser wavelength; mass spectrometry imaging; spatial resolution; surface roughness
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023

2023 article

Maximized Spatial Information and Minimized Acquisition Time of Top-Hat IR-MALDESI-MSI of Zebrafish Using Nested Regions of Interest (nROIs)

Joignant, A. N., Ritter, M. M., Knizner, K. T., Garrard, K. P., Kullman, S. W., & Muddiman, D. C. (2023, August 1). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 8.

By: A. Joignant n, M. Ritter n, K. Knizner n, K. Garrard n, S. Kullman n & D. Muddiman n

author keywords: IR-MALDESI; mass spectrometry imaging; spatialresolution; nested region of interest; zebrafish
TL;DR: The nROI method was characterized on mouse liver and applied to top-hat MSI of zebrafish using a novel optical train, which resulted in a significant improvement in both acquisition time and spatial detail of the zebra fish. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

SMART: A data reporting standard for mass spectrometry imaging

JOURNAL OF MASS SPECTROMETRY, 58(2).

By: Y. Xi n, A. Sohn n, A. Joignant n, S. Cologna*, B. Prentice* & D. Muddiman n

author keywords: data reporting standards; mass spectrometry imaging
MeSH headings : Research Design; Mass Spectrometry / methods; Ions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: The goal of this tutorial is to discuss the necessity of establishing a uniform reporting system to communicate MSI data in publications and presentations in a simple format to readily interpret the parameters and baseline outcomes of the data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: March 13, 2023

2022 journal article

Developing transmission mode for infrared matrix-assisted laser desorption electrospray ionization mass spectrometry imaging

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 36(22).

By: A. Joignant n, H. Bai n, J. Guymon n, K. Garrard n, M. Pankow n & D. Muddiman n

MeSH headings : Animals; Glycerol; Ice; Lasers; Mammals; Mice; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: This work has successfully demonstrated the adaptation of the NextGen IR‐MAL DESI source through the feasibility of tm‐IR‐MALDESI mass spectrometry imaging on mammalian tissue, expanding future biological applications of the method. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 26, 2022

2022 journal article

Improved spatial resolution of infrared matrix-assisted laser desorption electrospray ionization mass spectrometry imaging using a reflective objective

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 36(23).

By: A. Joignant n, H. Bai n, J. Manni & D. Muddiman n

MeSH headings : Animals; Spectrometry, Mass, Electrospray Ionization / methods; Ice; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Lasers; Mammals
Sources: Web Of Science, NC State University Libraries
Added: October 17, 2022

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