A. N. Novell

Works (6)

Updated: July 5th, 2023 15:42

2017 article

An evaluation of the sonoporation potential of low-boiling point phase-change ultrasound contrast agents in vitro

Fix, S. M., Novell, A., Yun, Y., Dayton, P. A., & Arena, C. B. (2017, January 21). Journal of Therapeutic Ultrasound.

By: S. Fix *, A. Novell n, Y. Yun *, P. Dayton n & C. Arena  n

author keywords: Sonoporation; Ultrasound; Drug delivery; Acoustic droplet vaporization; Nanodroplet
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound and Cavitation Phenomena; Ultrasound Imaging and Elastography
TL;DR: It is concluded that phase-change ultrasound contrast agents can be used to induce the sonoporation of cells in vitro, and the results warrant further investigation into the use of PCCAs as extravascularSonoporation agents in vivo. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2016 article

Wideband acoustic activation and detection of droplet vaporization events using a capacitive micromachined ultrasonic transducer

Novell, A., Arena, C. B., Oralkan, O., & Dayton, P. A. (2016, June 1). The Journal of the Acoustical Society of America, Vol. 139, pp. 3193–3198.

By: A. Novell n, C. Arena  n, O. Oralkan n  & P. Dayton n

MeSH headings : Contrast Media / chemistry; Equipment Design; Fluorocarbons / chemistry; Lipids / chemistry; Microbubbles; Time Factors; Transducers; Ultrasonography / instrumentation; Volatilization
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound Imaging and Elastography; Photoacoustic and Ultrasonic Imaging
TL;DR: This study exploited the wide bandwidth of a 128-element capacitive micromachined ultrasonic transducer array for activation and real-time imaging of ADV events from droplets circulating in a tube to provide a substantial increase of the contrast-to-noise ratio. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 article

Dual-frequency acoustic droplet vaporization detection for medical imaging

Arena, C. B., Novell, A., Sheeran, P. S., Puett, C., Moyer, L. C., & Dayton, P. A. (2015, September 1). IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control.

By: C. Arena  n, A. Novell n, P. Sheeran n, C. Puett  n, L. Moyer n & P. Dayton n

MeSH headings : Fluorocarbons / chemistry; Microbubbles; Microscopy, Acoustic / methods; Phantoms, Imaging; Transducers; Ultrasonography / methods
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Photoacoustic and Ultrasonic Imaging; Ultrasound Imaging and Elastography
TL;DR: Results indicate that it is possible to generate high-sensitivity, high-contrast images of vaporization events and has the potential to be applied in combination with dropletmediated therapy to track treatment outcomes or as a standalone diagnostic system to monitor the physical properties of the surrounding environment. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2014 article

Evaluation of bias voltage modulation sequence for nonlinear contrast agent imaging using a capacitive micromachined ultrasonic transducer array

Novell, A., Legros, M., Grégoire, J.-M., Dayton, P. A., & Bouakaz, A. (2014, August 7). Physics in Medicine and Biology.

By: A. Novell n, M. Legros *, J. Grégoire *, P. Dayton n & A. Bouakaz *

author keywords: amplitude modulation; bias voltage; cMUT; multi-pulse sequence; contrast agent imaging; harmonic; nonlinear behavior
MeSH headings : Algorithms; Contrast Media; Humans; Microbubbles; Phantoms, Imaging; Transducers; Ultrasonography / instrumentation; Ultrasonography / methods
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound Imaging and Elastography; Photoacoustic and Ultrasonic Imaging
TL;DR: A new contrast imaging sequence, called bias voltage modulation (BVM), specifically developed for cMUTs to suppress their inherent nonlinear behavior is proposed, revealing that the problem of cM UT nonlinearity can be addressed, thus expanding the potential of this new transducer technology for nonlinear contrast agent detection and imaging. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2014 journal article

Evaluation of chirp reversal power modulation sequence for contrast agent imaging

Physics in Medicine & Biology, 59(17), 5101–5117.

By: A. Novell, C. Sennoga, J. Escoffre, J. Chaline & A. Bouakaz

Source: NC State University Libraries
Added: August 6, 2018

2014 article

Ultrasound imaging from vaporization signals emitted by phase change contrast agents

B. Arena, Novell, S. Sheeran, Puett, C. Phillips, & A. Dayton. (2014, September 1).

By: . B. Arena n, . Novell  n, . S. Sheeran n, . Puett n, . C. Phillips n & . A. Dayton n

author keywords: acoustic droplet vaporization; contrast enhanced ultrasound; nanodroplet; nanoemulsion; perfluorocarbon
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Photoacoustic and Ultrasonic Imaging; Thermoregulation and physiological responses
TL;DR: It is demonstrated that this event can be used to generate an ultrasound image, and that the signal can be separated from that of a conventional microbubble. (via Semantic Scholar)
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7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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