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Works (27)
2026 article
The Environmental Health Language Collaborative (EHLC) Adverse Outcome Pathway (AOP) Standards Workshop Report
Mortensen, H., Hench, V., Nymark, P., Lynn, S., Hogberg, H., Feshuk, M., … Schmitt, C. (2026, February 26). F1000Research.
2025 article
Integrating AI-powered text mining from PubTator into the manual curation workflow at the Comparative Toxicogenomics Database
Wiegers, T. C., Davis, A. P., Wiegers, J., Sciaky, D., Barkalow, F., Wyatt, B., … Mattingly, C. J. (2025, January 1). Database, Vol. 2025.
2025 article
Linking chemical data from the Comparative Toxicogenomics Database with adverse outcome pathways from the AOP-Wiki: a mechanistic data-oriented approach to help inform environmental health
Davis, A. P., Wiegers, T. C., Sciaky, D., Barkalow, F., Wyatt, B., Wiegers, J., … Mattingly, C. J. (2025, November 17). F1000Research.
2024 article
Comparative Toxicogenomics Database’s 20th anniversary: update 2025
Davis, A. P., Wiegers, T. C., Sciaky, D., Barkalow, F., Strong, M., Wyatt, B., … Mattingly, C. J. (2024, October 10). Nucleic Acids Research, Vol. 10.
2024 article
Transforming environmental health datasets from the comparative toxicogenomics database into chord diagrams to visualize molecular mechanisms
Wyatt, B., Davis, A. P., Wiegers, T. C., Wiegers, J., Abrar, S., Sciaky, D., … Mattingly, C. J. (2024, July 22). Frontiers in Toxicology, Vol. 6.
2023 article
CTD tetramers: a new online tool that computationally links curated chemicals, genes, phenotypes, and diseases to inform molecular mechanisms for environmental health
Davis, A. P., Wiegers, T. C., Wiegers, J., Wyatt, B., Johnson, R. J., Sciaky, D., … Mattingly, C. J. (2023, July 21). Toxicological Sciences, Vol. 195, pp. 155–168.
2022 article
Comparative Toxicogenomics Database (CTD): update 2023
Davis, A. P., Wiegers, T. C., Johnson, R. J., Sciaky, D., Wiegers, J., & Mattingly, C. J. (2022, September 28). Nucleic Acids Research, Vol. 9.
2021 article
CTD anatomy: Analyzing chemical-induced phenotypes and exposures from an anatomical perspective, with implications for environmental health studies
Davis, A. P., Wiegers, T. C., Wiegers, J., Grondin, C. J., Johnson, R. J., Sciaky, D., & Mattingly, C. J. (2021, January 1). Current Research in Toxicology.
2021 article
Predicting molecular mechanisms, pathways, and health outcomes induced by Juul e-cigarette aerosol chemicals using the Comparative Toxicogenomics Database
Grondin, C. J., Davis, A. P., Wiegers, J. A., Wiegers, T. C., Sciaky, D., Johnson, R. J., & Mattingly, C. J. (2021, January 1). Current Research in Toxicology.
2021 article
Regulatory status of pesticide residues in cannabis: Implications to medical use in neurological diseases
Pinkhasova, D. V., Jameson, L. E., Conrow, K. D., Simeone, M. P., Davis, A. P., Wiegers, T. C., … Leung, M. C. K. (2021, January 1). Current Research in Toxicology.
2020 article
Comparative Toxicogenomics Database (CTD): update 2021
Davis, A. P., Grondin, C. J., Johnson, R. J., Sciaky, D., Wiegers, J., Wiegers, T. C., & Mattingly, C. J. (2020, October 1). Nucleic Acids Research, Vol. 49, pp. D1138–D1143.
2020 article
Leveraging the Comparative Toxicogenomics Database to Fill in Knowledge Gaps for Environmental Health: A Test Case for Air Pollution-induced Cardiovascular Disease
Davis, A. P., Wiegers, T. C., Grondin, C. J., Johnson, R. J., Sciaky, D., Wiegers, J., & Mattingly, C. J. (2020, July 8). Toxicological Sciences, Vol. 177, pp. 392–404.
2018 article
Accessing an Expanded Exposure Science Module at the Comparative Toxicogenomics Database
Grondin, C. J., Davis, A. P., Wiegers, T. C., Wiegers, J. A., & Mattingly, C. J. (2018, January 16). Environmental Health Perspectives, Vol. 126.
2018 article
Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways
Davis, A. P., Wiegers, T. C., Wiegers, J., Johnson, R. J., Sciaky, D., Grondin, C. J., & Mattingly, C. J. (2018, May 23). Toxicological Sciences, Vol. 165, pp. 145–156.
2018 article
The Comparative Toxicogenomics Database: update 2019
Davis, A. P., Grondin, C. J., Johnson, R. J., Sciaky, D., McMorran, R., Wiegers, J., … Mattingly, C. J. (2018, September 17). Nucleic Acids Research, Vol. 47, pp. D948–D954.
2016 journal article
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database
Environmental Health Perspectives, 124(10), 1592–1599.
Contributors: C. Grondin n, n, T. Wiegers n, B. King *, J. Wiegers n, D. Reif n , J. Hoppin n , C. Mattingly n
2016 article
Assessing the state of the art in biomedical relation extraction: overview of the BioCreative V chemical-disease relation (CDR) task
Wei, C.-H., Peng, Y., Leaman, R., Davis, A. P., Mattingly, C. J., Li, J., … Lu, Z. (2016, January 1). Database.
2016 article
BioCreative V CDR task corpus: a resource for chemical disease relation extraction
Li, J., Sun, Y. P., Johnson, R. J., Sciaky, D., Wei, C. H., Leaman, R., … al. (2016, January 1). Database.
2016 article
Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database
Davis, A. P., Wiegers, T. C., King, B. L., Wiegers, J., Grondin, C. J., Sciaky, D., … Mattingly, C. J. (2016, May 12). PLoS ONE, Vol. 11.
2016 article
The Comparative Toxicogenomics Database: update 2017
Davis, A. P., Grondin, C. J., Johnson, R. J., Sciaky, D., King, B. L., McMorran, R., … Mattingly, C. J. (2016, September 19). Nucleic Acids Research, Vol. 45, pp. D972–978.
2014 article
The Comparative Toxicogenomics Database's 10th year anniversary: update 2015
Davis, A. P., Grondin, C. J., Lennon-Hopkins, K., Saraceni-Richards, C., Sciaky, D., King, B. L., … Mattingly, C. J. (2014, October 17). Nucleic Acids Research, Vol. 43, pp. D914–920.
2014 article
Web services-based text-mining demonstrates broad impacts for interoperability and process simplification
Wiegers, T. C., Davis, A. P., & Mattingly, C. J. (2014, June 10). Database.
2013 article
A CTD-Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug-disease and drug-phenotype interactions
Davis, A. P., Wiegers, T. C., Roberts, P. M., King, B. L., Lay, J. M., Lennon-Hopkins, K., … Mattingly, C. J. (2013, November 28). Database.
2013 article
Text Mining Effectively Scores and Ranks the Literature for Improving Chemical-Gene-Disease Curation at the Comparative Toxicogenomics Database
Davis, A. P., Wiegers, T. C., Johnson, R. J., Lay, J. M., Lennon-Hopkins, K., Saraceni-Richards, C., … Mattingly, C. J. (2013, April 17). PLoS ONE, Vol. 8.
2012 article
Ranking Transitive Chemical-Disease Inferences Using Local Network Topology in the Comparative Toxicogenomics Database
King, B. L., Davis, A. P., Rosenstein, M. C., Wiegers, T. C., & Mattingly, C. J. (2012, November 7). PLoS ONE, Vol. 7.
2012 journal article
Targeted journal curation as a method to improve data currency at the Comparative Toxicogenomics Database
Database-The Journal of Biological Databases and Curation.
2012 journal article
The Comparative Toxicogenomics Database: update 2013
Nucleic Acids Research, 41(D1), D1104–D1114.