Works (67)
Updated: September 9th, 2023 05:02
2023 journal article
Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins
FRONTIERS IN NUTRITION, 10.
author keywords: astaxanthin; exercise; proteomics; oxylipins; inflammation; cytokines
www.frontiersin.org (publisher PDF)
Sources: Web Of Science, ORCID
Added: April 17, 2023
2023 review
Blueberry Supplementation and Skin Health
[Review of ]. ANTIOXIDANTS, 12(6).
author keywords: blueberries; skin; inflammation; polyphenol; antioxidant
Sources: Web Of Science, ORCID
Added: June 14, 2023
2023 article
CADMIUM EXPOSURE AFFECTS THE PROGRESSION OF HUMAN METASTATIC MELANOMA BY INDUCING A DEREGULATION OF ANTIOXIDANT CELL RESPONSE
Casoni, A., Benedusi, M., Cervellati, F., Pecorelli, A., Ferrara, F., Vallese, A., & Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 42–43.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
CONSTITUTIVE ACTIVATION OF NLRP3 INFLAMMASOME MACHINERY IN EX-VIVO MODELS OF RETT SYNDROME: FROM PATHOGENETIC ROLE TO NEW POTENTIAL THERAPEUTIC TARGET
Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 12–12.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
Deregulated NLRP3 inflammasome response due to a constitutive activation of NF-kappa B p65 pro-inflammatory pathway in lymphomonocytes of Rett syndrome patients
Cordone, V., Vallese, A., Pecorelli, A., Guiotto, A., Ferrara, F., Benedusi, M., … Valacchi, G. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S21–S22.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 journal article
Development of Spray Dried Spirulina Protein-Berry Pomace Polyphenol Particles to Attenuate Pollution-Induced Skin Damage: A Convergent Food-Beauty Approach
ANTIOXIDANTS, 12(7).
author keywords: sustainability; value-added; repurposing; skin health; cosmeceuticals
Sources: Web Of Science, ORCID
Added: July 17, 2023
2023 journal article
Evaluation of Anti-Oxinflammatory and ACE-Inhibitory Properties of Protein Hydrolysates Obtained from Edible Non-Mulberry Silkworm Pupae (Antheraea assama and Philosomia ricinii)
NUTRIENTS, 15(4).
author keywords: non-mulberry silkworm pupae; angiotensin converting enzyme-inhibitory peptides; antioxidative peptides; ultrafiltration; anti-inflammatory peptides
MeSH headings : Animals; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Antioxidants / pharmacology; Protein Hydrolysates / pharmacology; Bombyx; Pupa; Endothelial Cells; Lipopolysaccharides; Peptides / pharmacology; Hypertension; Hydrolysis
Sources: Web Of Science, ORCID
Added: March 20, 2023
2023 article
INFLAMMASOMES REGULATION BY ENVIRONMENTAL POLLUTANTS IN HUMAN SKIN
Ferrara, F., Pecorelli, A., Guiotto, A., Vallese, A., Cordone, V., Benedusi, M., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 38–39.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
MITOCHONDRIAL DYSFUNCTION AND NLRP3 INFLAMMASOME ACTIVATION IN AUTISM SPECTRUM DISORDER
Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 20–20.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
Mitochondria and inflammasome involvement in Autism Spectrum Disorder
Pecorelli, A. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S2–S2.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 journal article
Ox-inflammasome involvement in neuroinflammation
FREE RADICAL BIOLOGY AND MEDICINE, 207, 161–177.
Sources: Web Of Science, ORCID
Added: September 5, 2023
2023 article
ROLE OF COENZYME Q10 IN MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE DAMAGE IN RETT SYNDROME
Silvestri, S., Marcheggiani, F., Orlando, P., Cirilli, I., Mengarelli, F., Vallese, A., … Tiano, L. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 16–16.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
THE PROTECTIVE ROLE OF ENDOTHELIAL alpha 1AMPK IN AIRCRAFT NOISE-INDUCED VASCULAR DYSFUNCTION AND OXIDATIVE STRESS IS MEDIATED BY FASTING, EXERCISE AND PHARMACOLOGICAL TREATMENT
Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 11–12.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2022 article
Aberrant Mitochondrial Bioenergetics Fuels Inflammasome Machinery in Autism Spectrum Disorder
Pecorelli, A., Francesca, F., Cordone, V., Guiotto, A., Cervellati, C., Hayek, J., & Valacchi, G. (2022, February 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 180, pp. 97–98.
Sources: Web Of Science, ORCID
Added: April 25, 2022
2022 article
Involvement Of Ferroptosis In Rett Syndrome
Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Cervellati, C., Hayek, J., … Pecorelli, A. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 article
Loss of Scavenger Receptor B1 (SR-B1) in Brain of a Rett Syndrome Mouse Model
Pecorelli, A., Ferrara, F., Guiotto, A., Vallese, A., Cordone, V., Belmonte, G., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 article
Mutations Specific Redox Regulation Pathway In Rett Syndrome By The Use Of Transcriptomics And Proteomics Approaches
Pasqui, A., Cicaloni, V., Tinti, L., Mori, A., Bruttini, M., Pecorelli, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 review
Oxidative-Stress-Sensitive microRNAs in UV-Promoted Development of Melanoma
[Review of ]. CANCERS, 14(13).
author keywords: skin cancer; sunlight; redox imbalance; miRNome; mutations; epigenome
Sources: Web Of Science, ORCID
Added: July 26, 2022
2022 journal article
The constitutive activation of TLR4-IRAK1-NF kappa B axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients
FREE RADICAL BIOLOGY AND MEDICINE, 181, 1–13.
author keywords: MeCP2; p65; Oxinflammation; Interleukin-18; Interleukin-1 beta
MeSH headings : Humans; Inflammasomes / genetics; Inflammasomes / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Leukocytes, Mononuclear / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Toll-Like Receptor 4 / genetics
Sources: Web Of Science, ORCID
Added: March 14, 2022
2022 journal article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
REDOX BIOLOGY, 56.
author keywords: Inflammasomes; OxInflammation; Proteasome; UBR2; N-end rule pathway
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Air Pollutants; Apoptosis Regulatory Proteins / genetics; Catalase / metabolism; Cytokines / metabolism; Environmental Pollutants; Humans; Hydrogen Peroxide / metabolism; Inflammasomes / metabolism; NLR Proteins / metabolism; Oxidation-Reduction; Ozone / metabolism; Particulate Matter; Reactive Oxygen Species / metabolism; Ubiquitin-Protein Ligases / metabolism; Ubiquitination
Sources: Web Of Science, ORCID
Added: September 12, 2022
2022 article
Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation
Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2021 journal article
Alaskan Bog Blueberry (Vaccinium uliginosum) Extract as an Innovative Topical Approach to Prevent UV-Induced Skin Damage
COSMETICS, 8(4).
author keywords: cosmeceuticals; environmental stressor; oxidation; inflammation; antioxidant; OxInflammation; phytochemicals
Sources: Web Of Science, ORCID
Added: December 2, 2021
2021 article
Alteration of cellular defensive response and a possible involvement of ferroptosis cell death in Rett syndrome disorder
Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2021 journal article
Alterations in oxygen metabolism are associated to lung toxicity triggered by silver nanoparticles exposure
FREE RADICAL BIOLOGY AND MEDICINE, 166, 324–336.
author keywords: Nanoparticles; Lung epithelium; Nanotoxicology; Oxidative metabolism; NADPH oxidase; Mitochondria
MeSH headings : Animals; Hydrogen Peroxide; Lung; Metal Nanoparticles / toxicity; Mice; Oxygen; Silver
Sources: Web Of Science, ORCID
Added: April 19, 2021
2021 review
Altered Bone Status in Rett Syndrome
[Review of ]. LIFE-BASEL, 11(6).
author keywords: MeCP2; bone mineral density; bone metabolism; osteoblast; WNT pathway
Sources: Web Of Science, ORCID
Added: July 12, 2021
2021 journal article
Deferoxamine Treatment Improves Antioxidant Cosmeceutical Formulation Protection against Cutaneous Diesel Engine Exhaust Exposure
ANTIOXIDANTS, 10(12).
author keywords: cosmeceuticals; pollution; iron-chelator
Sources: Web Of Science, ORCID
Added: January 24, 2022
2021 article
Deregulated inflammasome response in Rett syndrome
Cordone, V., Pecorelli, A., Falone, S., Hayek, J., Amicarelli, F., & Valacchi, G. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177.
Sources: Web Of Science, ORCID
Added: February 21, 2022
2021 journal article
Impaired mitochondrial quality control in Rett Syndrome
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 700.
author keywords: RTT Syndrome; Oxidative stress; Mitochondrial quality control; Mitophagy; Apoptosis
MeSH headings : Adolescent; Adult; Apoptosis; Caspase 3 / genetics; Caspase 3 / metabolism; Caspase 7 / genetics; Caspase 7 / metabolism; Child; Dynamins / genetics; Dynamins / metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Humans; Membrane Proteins / genetics; Membrane Proteins / metabolism; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mitochondria / genetics; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Membrane Transport Proteins / genetics; Mitochondrial Membrane Transport Proteins / metabolism; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Mitophagy; Oxidation-Reduction; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Web Of Science, ORCID
Added: March 15, 2021
2021 article
Improper enzymatic defensive responses in Rett syndrome disorder
Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177.
Sources: Web Of Science, ORCID
Added: February 21, 2022
2021 article
Mitochondrial dynamics and quality control pathways impairment in Rett Syndrome and Autism Spectrum Disorder
Pecorelli, A., Guiotto, A., Cordone, V., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177, pp. S17–S18.
Sources: Web Of Science, ORCID
Added: February 28, 2022
2021 article
Mitochondrial dysfunction fuels inflammasome machinery in Autism Spectrum Disorder
Pecorelli, A., Cordone, V., Guiotto, A., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2021 journal article
Novel Spray Dried Algae-Rosemary Particles Attenuate Pollution-Induced Skin Damage
MOLECULES, 26(13).
author keywords: cosmeceuticals; pollution; phytochemicals; herbs
MeSH headings : Antioxidants / chemistry; Antioxidants / pharmacology; Cells, Cultured; Chlorella / chemistry; Cinnamates / chemistry; Depsides / chemistry; Environmental Exposure / adverse effects; Filaggrin Proteins; Humans; Rosmarinus / chemistry; Skin / injuries; Skin / metabolism; Skin / pathology; Skin Aging / drug effects
Sources: Web Of Science, ORCID
Added: June 23, 2021
2021 journal article
Protective effects of a comprehensive topical antioxidant against ozone-induced damage in a reconstructed human skin model
ARCHIVES OF DERMATOLOGICAL RESEARCH, 313(3), 139–146.
author keywords: Antioxidants; Ozone; Oxidative damage; Cosmeceuticals; Free radicals; Reactive Oxygen Species (ROS)
MeSH headings : Administration, Cutaneous; Antioxidants / administration & dosage; Cell Culture Techniques; Cells, Cultured; Drug Evaluation, Preclinical; Epidermis / drug effects; Epidermis / pathology; Humans; Lipid Peroxidation / drug effects; Oxidative Stress / drug effects; Ozone / adverse effects; Reactive Oxygen Species / metabolism; Skin Aging / drug effects
Sources: Web Of Science, ORCID
Added: May 26, 2020
2021 journal article
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents
ACS CHEMICAL NEUROSCIENCE, 12(9), 1716–1736.
author keywords: Endocannabinoid system; fatty acid amide hydrolase; enzyme inhibitors; selective inhibitors; epilepsy; temporal lobe epilepsy; seizures
MeSH headings : Amidohydrolases; Anticonvulsants / pharmacology; Endocannabinoids; Enzyme Inhibitors / pharmacology; Humans; Seizures
Sources: Web Of Science, ORCID
Added: June 10, 2021
2021 article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
Ferrara, F., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2020 journal article
A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 696.
author keywords: Rare disease; Rett syndrome; Inflammatory status; NLRP3 inflammasome; Mass spectrometry-based proteomics
MeSH headings : Adult; Female; Fibroblasts / chemistry; Humans; Inflammation / complications; Inflammation / metabolism; Protein Interaction Maps; Proteome / analysis; Proteome / metabolism; Proteomics; Rett Syndrome / complications; Rett Syndrome / metabolism; Young Adult
Sources: Web Of Science, ORCID
Added: January 19, 2021
2020 journal article
Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder
FASEB JOURNAL, 34(5), 6521–6538.
author keywords: 4-hydroxynonenal; fission; fusion; mitophagy; nuclear factor erythroid 2-related factor 2
MeSH headings : Adolescent; Adult; Autism Spectrum Disorder / metabolism; Autism Spectrum Disorder / pathology; Case-Control Studies; Child; Energy Metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; Humans; Male; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Dynamics; Mitochondrial Proteins / metabolism; Oxidative Stress; Young Adult
Sources: Web Of Science, ORCID
Added: April 20, 2020
2020 journal article
Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation
REDOX BIOLOGY, 28.
author keywords: NLRP3; ASC; Inflammatory status; Cytokines; MeCP2
MeSH headings : Biomarkers; Cytokines / metabolism; Disease Susceptibility; Fibroblasts / metabolism; Fluorescent Antibody Technique; Humans; Inflammasomes / metabolism; Inflammation Mediators / metabolism; Interleukin-1beta / metabolism; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Protein Transport; Rett Syndrome / etiology; Rett Syndrome / metabolism
Sources: Web Of Science, ORCID
Added: December 30, 2019
2020 journal article
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1866(7).
author keywords: Rett syndrome; Skin primary fibroblasts; Proteasome; alpha-Ring; PAC1; PAC2
MeSH headings : Codon, Nonsense / genetics; Dual Specificity Phosphatase 2 / genetics; Fibroblasts / metabolism; Gene Expression Regulation; Genetic Diseases, X-Linked / genetics; Genetic Diseases, X-Linked / pathology; Humans; Methyl-CpG-Binding Protein 2 / genetics; Neurodevelopmental Disorders / genetics; Neurodevelopmental Disorders / pathology; Primary Cell Culture; Proteasome Endopeptidase Complex / genetics; Proteolysis; Rett Syndrome / genetics; Rett Syndrome / pathology; Skin / metabolism; Skin / pathology; Ubiquitin / genetics
Sources: Web Of Science, ORCID
Added: June 15, 2020
2020 journal article
Gallic acid loaded poloxamer gel as new adjuvant strategy for melanoma: A preliminary study
COLLOIDS AND SURFACES B-BIOINTERFACES, 185.
author keywords: Biocompatible polymers; Polymer gels; In vitro diffusion; Polymer membranes; Gallic acid; Franz cell
MeSH headings : Adjuvants, Immunologic / pharmacology; Adjuvants, Immunologic / therapeutic use; Cell Line; Cell Movement / drug effects; Diffusion; Elasticity; Gallic Acid / pharmacology; Gallic Acid / therapeutic use; Gels / chemistry; Humans; Kinetics; Melanoma / drug therapy; Phase Transition; Poloxamer / chemistry; Rheology; Temperature; Viscosity; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: January 13, 2020
2020 journal article
Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery
ANTIOXIDANTS & REDOX SIGNALING, 33(3), 191–210.
author keywords: Alzheimer's disease; inflammation; multiple sclerosis; vascular dementia
MeSH headings : Animals; Biomarkers; Blood-Brain Barrier / metabolism; Brain / metabolism; Brain / pathology; Disease Susceptibility; Dysbiosis; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Nervous System Diseases / etiology; Nervous System Diseases / metabolism; Nervous System Diseases / pathology; Oxidative Stress; Peripheral Nerves / metabolism; Peripheral Nerves / pathology
Sources: Web Of Science, ORCID
Added: April 27, 2020
2020 journal article
Mechanisms involved in the unbalanced redox homeostasis in osteoblastic cellular model of Alkaptonuria
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 690.
author keywords: Alkaptonuria; Osteoblast; Oxidative stress; Nrf2; Mitochondria; NADPH oxidase
MeSH headings : Alkaptonuria / metabolism; Cell Line; DNA-Binding Proteins / metabolism; Homeostasis / physiology; Homogentisic Acid / metabolism; Humans; Hydrogen Peroxide / metabolism; Mitochondria / metabolism; Mitochondria / ultrastructure; NADPH Oxidases / metabolism; NF-E2-Related Factor 2 / metabolism; Osteoblasts / cytology; Oxidation-Reduction; Oxidative Stress / physiology; Signal Transduction; Superoxide Dismutase / metabolism; Thioredoxins / metabolism
Sources: Web Of Science, ORCID
Added: January 19, 2021
2020 journal article
Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119.
author keywords: inflammation exercise; oxidative stress; peripheral blood mononuclear cells
Sources: Web Of Science, ORCID
Added: July 6, 2020
2020 journal article
Postexercise Inflammasome Activation and IL-1 beta Production Mitigated by Flavonoid Supplementation in Cyclists
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(6), 396–404.
author keywords: cytokines; gasdermin D; IL-18; inflammation
Sources: Web Of Science, ORCID
Added: November 9, 2020
2020 journal article
Proteomic pro fi ling reveals mitochondrial alterations in Rett syndrome
FREE RADICAL BIOLOGY AND MEDICINE, 155, 37–48.
MeSH headings : Gene Expression Profiling; Humans; Methyl-CpG-Binding Protein 2 / genetics; Mutation; Proteome / genetics; Proteomics; Rett Syndrome / genetics
Sources: Web Of Science, ORCID
Added: July 6, 2020
2020 journal article
Redox regulation of cutaneous inflammasome by ozone exposure
FREE RADICAL BIOLOGY AND MEDICINE, 152, 561–570.
MeSH headings : Caspase 1 / metabolism; Humans; Hydrogen Peroxide; Inflammasomes / metabolism; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Oxidation-Reduction; Ozone / toxicity; Reactive Oxygen Species
Sources: Web Of Science, ORCID
Added: July 13, 2020
2020 article
Skin Health from the Inside Out
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 235–254.
author keywords: pollution; skin; diet; GI tract; inflammation; antioxidant; vitamins
MeSH headings : Antioxidants / metabolism; Humans; Reactive Oxygen Species / metabolism; Skin Physiological Phenomena
Sources: Web Of Science, ORCID
Added: April 27, 2020
2019 journal article
13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation
FREE RADICAL BIOLOGY AND MEDICINE, 134, 598–603.
author keywords: Rett syndrome; Oxidative stress; Hydroxyoctadecadienoic acids; Inflammation; Omega-3 polyunsaturated fatty acids; Arachidonate 15-Lipoxygenase
MeSH headings : Adolescent; Adult; Arachidonate 15-Lipoxygenase / genetics; Arachidonate 15-Lipoxygenase / metabolism; Case-Control Studies; Child; Female; Humans; Inflammation / genetics; Inflammation / metabolism; Inflammation / pathology; Leukocytes, Mononuclear / metabolism; Linoleic Acids / metabolism; Linoleic Acids, Conjugated / metabolism; Male; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology; Young Adult
Sources: Web Of Science, ORCID
Added: July 1, 2019
2019 journal article
Antiglycative Activity and RAGE Expression in Rett Syndrome
CELLS, 8(2).
author keywords: methylglyoxal; glyoxalases; advanced glycation end products; MeCP2; dicarbonyl stress; fibroblasts
MeSH headings : Adolescent; Adult; Antigens, Neoplasm / metabolism; Cell Survival / drug effects; Child; Female; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosylation; Humans; Lactoylglutathione Lyase / metabolism; Mitogen-Activated Protein Kinases / metabolism; Pyruvaldehyde / pharmacology; Rett Syndrome / metabolism; Rett Syndrome / pathology; Thiolester Hydrolases / metabolism; Young Adult
Sources: Web Of Science, ORCID
Added: March 25, 2019
2019 article
Blueberries Topical Application Prevents Ozone Induced Cutaneous Inflammasome Activation
Pambianchi, E., Francesca, F., Pecorelli, A., Woodby, B., Lila, M., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S148–S148.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 journal article
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 183.
author keywords: Endocannabinoid system; Fatty acid amide hydrolase; Enzyme inhibitors; Selective inhibitors; Dopamine ligands; Polypharmacology; Multitarget compounds; Dopamine receptor ligands
MeSH headings : Amidohydrolases / antagonists & inhibitors; Amidohydrolases / metabolism; Binding, Competitive; Cell Line; Cell Survival / drug effects; Dopamine / metabolism; Endocannabinoids / metabolism; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans; Ligands; Piperazines / chemistry; Piperazines / pharmacology; Pyrroles / chemistry; Pyrroles / pharmacology
Sources: Web Of Science, ORCID
Added: December 16, 2019
2019 article
HGA Induces Oxidative Damage in an Ostcoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms HGA Induces Oxidative Damage in an Osteoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms
Schiavone, M. L., Pecorelli, A., Woodby, B., Ferrara, F., Santucci, A., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S37–S38.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 review
Involvement of 4-hydroxy-2-nonenal in pollution-induced skin damage
[Review of ]. BIOFACTORS, 45(4), 536–547.
author keywords: ozone; particulate matter; cigarette smoke; peroxidation
MeSH headings : Air Pollutants / metabolism; Air Pollutants / toxicity; Aldehydes / metabolism; Aldehydes / toxicity; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / genetics; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Gene Expression Regulation / drug effects; Humans; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; Oxidation-Reduction; Oxidative Stress; Ozone / metabolism; Ozone / toxicity; Particulate Matter / toxicity; Psoriasis / chemically induced; Psoriasis / genetics; Psoriasis / metabolism; Psoriasis / pathology; Reactive Oxygen Species / agonists; Reactive Oxygen Species / metabolism; Signal Transduction; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Aging / drug effects; Skin Aging / genetics; Skin Aging / pathology; Tobacco Smoke Pollution / adverse effects; Transcription Factors / genetics; Transcription Factors / metabolism
Sources: Web Of Science, ORCID
Added: April 20, 2020
2019 journal article
Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells
BIOFACTORS, 45(6), 920–929.
author keywords: apoptosis; ER stress; melanoma; mitochondria; protein synthesis; rottlerin
Sources: Web Of Science, ORCID
Added: August 26, 2019
2019 article
OxInflammation as a Aossible new Player in Rett Syndrome Pathophysiology
Pecorelli, A., Valacchi, G., Cordone, V., & Hayek, J. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S149–S149.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 article
Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure
Ferrara, F., Pecorelli, A., Woodby, B., Pambianchi, E., Messano, N., Therrien, J. P., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 article
Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure
FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.
Source: ORCID
Added: December 3, 2019
2019 article
Redox-Regulation of Antimicrobial Peptides
Woodby, B., Pambianchi, E., Francesca, F., Messano, N., Pecorelli, A., Therrien, J. P., & Valacchii, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S54–S55.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2018 article
AtmO(3)spheric skin damage: The oxInflammation phenomena
Valacchi, G., Pecorelli, A., Pambianchi, E., Ferrara, F., & Lila, M. (2018, September). JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B15–B15.
Sources: Web Of Science, ORCID
Added: October 19, 2018
2018 article
Inflammasome involvement in Rett syndrome subclinical inflammation
Pecorelli, A., Cordone, V., Falone, S., Romani, A., Benedusi, M., Hayek, J., … Valacchi, G. (2018, November 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 128, pp. S108–S109.
Sources: Web Of Science, ORCID
Added: November 19, 2018
2018 journal article
Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure
MECHANISMS OF AGEING AND DEVELOPMENT, 172, 86–95.
author keywords: Air pollution; Particulate matter; Oxidative damage; Inflammation
MeSH headings : Cell Line, Transformed; Humans; Interleukin-1alpha / metabolism; Keratinocytes / metabolism; Keratinocytes / pathology; NF-E2-Related Factor 2 / metabolism; NF-kappa B / metabolism; Oxidation-Reduction / drug effects; Particulate Matter / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 review
OxInflammation: From Subclinical Condition to Pathological Biomarker
[Review of ]. FRONTIERS IN PHYSIOLOGY, 9.
author keywords: biomarkers; neurological disorders; oxidative stress; inflammation mediators; NF kappa B
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells
FREE RADICAL BIOLOGY AND MEDICINE, 126, 287–295.
MeSH headings : A549 Cells; Aldehydes / metabolism; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Antioxidants / pharmacology; Biological Transport / drug effects; Catalase / genetics; Catalase / metabolism; Cell Survival / drug effects; Humans; Hydrogen Peroxide / metabolism; Lung / drug effects; Lung / metabolism; Lung / pathology; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Ozone / pharmacology; Protein Processing, Post-Translational / drug effects; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / metabolism; Vitamin E / metabolism
Sources: Web Of Science, ORCID
Added: October 16, 2018
2017 review
4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation
[Review of ]. FREE RADICAL BIOLOGY AND MEDICINE, 111, 270–280.
author keywords: Inflammation; Isoprostanes; Oxidative stress; Rare disease; Orphan disease; CDKL5; FOXG1; MecP2
MeSH headings : Aldehydes / metabolism; Brain / metabolism; Brain / pathology; Feedback, Physiological; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Humans; Inflammation; Isoprostanes / metabolism; Lipid Peroxidation / genetics; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mutation; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Oxidative Stress; Proteasome Endopeptidase Complex / metabolism; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
First dual AK/GSK-3 beta inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 138, 438–457.
author keywords: Antioxidant agents; Glycogen synthase kinase 3 beta (GSK-3 beta); Adenosine kinase (AK); Dual inhibitors; Molecular docking
MeSH headings : Adenosine Kinase / antagonists & inhibitors; Adenosine Kinase / metabolism; Antioxidants / chemical synthesis; Antioxidants / chemistry; Antioxidants / pharmacology; Cell Line, Tumor; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3 beta / antagonists & inhibitors; Glycogen Synthase Kinase 3 beta / metabolism; Humans; Hydrogen Peroxide / antagonists & inhibitors; Hydrogen Peroxide / pharmacology; Molecular Structure; Neuroblastoma / metabolism; Neuroblastoma / pathology; Neuroprotective Agents / chemical synthesis; Neuroprotective Agents / chemistry; Neuroprotective Agents / pharmacology; Oxidative Stress / drug effects; Protein Kinase Inhibitors / chemical synthesis; Protein Kinase Inhibitors / chemistry; Protein Kinase Inhibitors / pharmacology; Reactive Oxygen Species / metabolism; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study
MOLECULES, 22(12).
author keywords: anti-inflammatory; artificial tears; corneal epithelium; cyclin D1; dry eye syndrome; HA; HA-CL; IL-8; re-epithelialization
MeSH headings : Analysis of Variance; Biomarkers; Cell Line; Cell Survival; Cyclin D1 / metabolism; Drug Stability; Dry Eye Syndromes; Epithelium, Corneal / drug effects; Humans; Hyaluronic Acid / analysis; Hyaluronic Acid / chemistry; Hydrogen-Ion Concentration; Lubricant Eye Drops / analysis; Lubricant Eye Drops / chemical synthesis; Lubricant Eye Drops / chemistry; Lubricant Eye Drops / pharmacology; Re-Epithelialization / drug effects; Viscosity; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Ascorbic Acid / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Connexin 43 / genetics; Connexin 43 / metabolism; Humans; Melanoma / drug therapy; Melanoma / pathology; Microscopy, Electron, Scanning; Potassium / chemistry; Ribose / chemistry; Spheroids, Cellular / drug effects; Spheroids, Cellular / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018
