@article{richter_bharti_arrnstrong_brown_plemmons_paunov_stoyanov_velev_2016, title={Synthesis and characterization of biodegradable lignin nanoparticles with tunable surface properties}, volume={32}, number={25}, journal={Langmuir}, author={Richter, A. P. and Bharti, B. and Arrnstrong, H. B. and Brown, J. S. and Plemmons, D. and Paunov, V. N. and Stoyanov, S. D. and Velev, O. D.}, year={2016}, pages={6468–6477} } @article{richter_brown_bharti_wang_gangwal_houck_hubal_paunov_stoyanov_velev_et al._2015, title={An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core}, volume={10}, ISSN={["1748-3395"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84941042177&partnerID=MN8TOARS}, DOI={10.1038/nnano.2015.141}, abstractNote={Silver nanoparticles have antibacterial properties, but their use has been a cause for concern because they persist in the environment. Here, we show that lignin nanoparticles infused with silver ions and coated with a cationic polyelectrolyte layer form a biodegradable and green alternative to silver nanoparticles. The polyelectrolyte layer promotes the adhesion of the particles to bacterial cell membranes and, together with silver ions, can kill a broad spectrum of bacteria, including Escherichia coli, Pseudomonas aeruginosa and quaternary-amine-resistant Ralstonia sp. Ion depletion studies have shown that the bioactivity of these nanoparticles is time-limited because of the desorption of silver ions. High-throughput bioactivity screening did not reveal increased toxicity of the particles when compared to an equivalent mass of metallic silver nanoparticles or silver nitrate solution. Our results demonstrate that the application of green chemistry principles may allow the synthesis of nanoparticles with biodegradable cores that have higher antimicrobial activity and smaller environmental impact than metallic silver nanoparticles. Biodegradable lignin nanoparticles infused with minimal amounts of silver ions and coated with a cationic polyelectrolyte show short-term broad-spectrum antimicrobial activity, offering an environmentally friendly alternative to metallic silver nanoparticles.}, number={9}, journal={NATURE NANOTECHNOLOGY}, author={Richter, A.P. and Brown, J.S. and Bharti, B. and Wang, A. and Gangwal, S. and Houck, K. and Hubal, E.A. Cohen and Paunov, V.N. and Stoyanov, S.D. and Velev, Orlin and et al.}, year={2015}, month={Sep}, pages={817-+} } @article{frangville_rutkevicius_richter_velev_stoyanov_paunov_2012, title={Fabrication of Environmentally Biodegradable Lignin Nanoparticles}, volume={13}, ISSN={["1439-7641"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84872833784&partnerID=MN8TOARS}, DOI={10.1002/cphc.201200537}, abstractNote={Abstract}, number={18}, journal={CHEMPHYSCHEM}, author={Frangville, Camille and Rutkevicius, Marius and Richter, Alexander P. and Velev, Orlin D. and Stoyanov, Simeon D. and Paunov, Vesselin N.}, year={2012}, month={Dec}, pages={4235–4243} }