Adam Steven Mullis

Works (1)

Updated: July 5th, 2023 15:41

2015 journal article

Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression

NUCLEIC ACIDS RESEARCH, 43(1), 674–681.

By: M. Luo n, A. Mullis n, R. Leenay n & C. Beisel n

MeSH headings : CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Cell Engineering; Escherichia coli / genetics; Gene Deletion; Transcription, Genetic
topics (OpenAlex): CRISPR and Genetic Engineering; Insect symbiosis and bacterial influences; Innovation and Socioeconomic Development
TL;DR: It is found that deletion of the signature cas3 gene converted this immune system in Escherichia coli into a programmable gene regulator capable of reversible gene silencing of heterologous and endogenous genes. (via Semantic Scholar)
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