Ashlyn T. Young

Works (12)

Updated: July 13th, 2023 21:14
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2021 journal article

Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses

COLLOIDS AND SURFACES B-BIOINTERFACES, 204.

By: C. Roosa n, I. Muhamed n, A. Young n, K. Nellenbach n, M. Daniele n, F. Ligler n, A. Brown n

co-author countries: United States of America 🇺🇸
author keywords: Fibrin; Nanoparticles; Wound healing; Regenerative medicine; Fibrin sealant
MeSH headings : Fibrin; Fibrin Tissue Adhesive; Nanoparticles; Polymerization; Wound Healing
Source: Web Of Science
Added: July 19, 2021

2020 journal article

Chitosan Hydrogels for Synergistic Delivery of Chemotherapeutics to Triple Negative Breast Cancer Cells and Spheroids

PHARMACEUTICAL RESEARCH, 37(7).

By: J. Schneible n, A. Young n, M. Daniele n & S. Menegatti n 

co-author countries: United States of America 🇺🇸
MeSH headings : Acetylation; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Antineoplastic Combined Chemotherapy Protocols / pharmacology; Cell Line, Tumor; Cell Survival / drug effects; Chitosan / chemistry; Deoxycytidine / administration & dosage; Deoxycytidine / analogs & derivatives; Deoxycytidine / chemistry; Deoxycytidine / pharmacology; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers; Drug Compounding; Drug Liberation; Drug Synergism; Female; Humans; Hydrogels; Kinetics; Spheroids, Cellular; Triple Negative Breast Neoplasms / drug therapy; Triple Negative Breast Neoplasms / pathology; Gemcitabine
Sources: Web Of Science, ORCID
Added: August 10, 2020

2020 journal article

Modified gaphene oxide (GO) particles in peptide hydrogels: a hybrid system enabling scheduled delivery of synergistic combinations of chemotherapeutics

JOURNAL OF MATERIALS CHEMISTRY B, 8(17), 3852–3868.

By: J. Schneible n, K. Shi n, A. Young n, S. Ramesh n, N. He*, C. Dowdey n, J. Dubnansky n, R. Libya ...

co-author countries: United States of America 🇺🇸
MeSH headings : Antibiotics, Antineoplastic / chemistry; Antibiotics, Antineoplastic / pharmacology; Cell Proliferation / drug effects; Cell Survival / drug effects; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Delivery Systems; Drug Screening Assays, Antitumor; Graphite / chemistry; Humans; Hydrogels / chemistry; Molecular Dynamics Simulation; Particle Size; Peptides / chemistry; Surface Properties; Tumor Cells, Cultured
Sources: Web Of Science, ORCID
Added: June 1, 2020

2020 journal article

Perylene-diimide-based n-type semiconductors with enhanced air and temperature stable photoconductor and transistor properties

DYES AND PIGMENTS, 174.

By: J. Yuen*, V. Pozdin n, A. Young n, B. Turner n, I. Giles*, J. Naciri*, S. Trammell*, P. Charles*, D. Stenger *, M. Daniele n

co-author countries: United States of America 🇺🇸
author keywords: Perylene; n-type; Photoconductor; Field effect transistor; Air stable
Source: Web Of Science
Added: February 17, 2020

2020 journal article

Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides

JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413–7427.

By: K. Day n, J. Schneible n, A. Young n, V. Pozdin*, G. Driessche  n, L. Gaffney n, R. Prodromou n, D. Freytes n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
Sources: Web Of Science, ORCID
Added: September 14, 2020

2020 journal article

Rheological Properties of Coordinated Physical Gelation and Chemical Crosslinking in Gelatin Methacryloyl (GelMA) Hydrogels

MACROMOLECULAR BIOSCIENCE, 20(12).

By: A. Young n, O. White n & M. Daniele n

co-author countries: United States of America 🇺🇸
author keywords: animal source; gelatin; gelatin methacryloyl; gelation; GelMA; mechanical properties; photopolymerization
MeSH headings : Animals; Biocompatible Materials / chemistry; Bioprinting / methods; Cattle; Gelatin / chemistry; Hydrogels / chemistry; Methacrylates / chemistry; Printing, Three-Dimensional; Rheology; Swine; Tissue Engineering / trends
Source: Web Of Science
Added: September 14, 2020

2019 journal article

Integrated phosphorescence-based photonic biosensor (iPOB) for monitoring oxygen levels in 3D cell culture systems

BIOSENSORS & BIOELECTRONICS, 123, 131–140.

By: K. Rivera n, V. Pozdin n, A. Young n, P. Erb n, N. Wisniewski*, S. Magness n, M. Daniele n

co-author countries: United States of America 🇺🇸
author keywords: Oxygen; Microdevice; Organs-on-chips; Oxygen biosensor; Biosensors; Hypoxia
MeSH headings : Biosensing Techniques; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Humans; Luminescent Measurements / methods; Oxygen / chemistry; Oxygen / metabolism; Photons
Source: Web Of Science
Added: December 3, 2018

2019 review

Monitoring of Microphysiological Systems: Integrating Sensors and Real-Time Data Analysis toward Autonomous Decision-Making

[Review of ]. ACS SENSORS, 4(6), 1454–1464.

By: A. Young n, K. Rivera n, P. Erb n & M. Daniele n

co-author countries: United States of America 🇺🇸
author keywords: microphysiological system (MPS); organ-on-chip; biosensor; real-time analysis; data; cyber-physical system
MeSH headings : Data Analysis; Humans; Lab-On-A-Chip Devices; Machine Learning; Microchip Analytical Procedures / methods; Monitoring, Physiologic / instrumentation; Monitoring, Physiologic / methods
Source: Web Of Science
Added: July 22, 2019

2019 journal article

Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury

ADVANCED FUNCTIONAL MATERIALS, 29(4).

By: T. Su n, K. Huang n , H. Ma *, H. Liang n, P. Dinh n, J. Chen n, D. Shen n, T. Allen n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019

2018 journal article

Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction

ACS APPLIED MATERIALS & INTERFACES, 10(39), 33088–33096.

By: T. Su n, K. Huang n , M. Daniele n, M. Hensley n, A. Young n, J. Tang n, T. Allen n, A. Vandergriff  n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: microvessels; hydrodynamic focusing; cardiac stem cells; cardiomyocyte proliferation; angiogenesis; myocardial infarction
MeSH headings : Animals; Cells, Cultured; Female; Human Umbilical Vein Endothelial Cells; Humans; Microfluidic Analytical Techniques; Myocardial Infarction / therapy; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / physiology; Neovascularization, Physiologic / physiology; Rats; Rats, Nude; Stem Cells / cytology; Stem Cells / physiology
Sources: Web Of Science, ORCID
Added: October 29, 2018

2018 journal article

Neuro-nano interfaces: Utilizing nano-coatings and nanoparticles to enable next-generation electrophysiological recording, neural stimulation, and biochemical modulation

Advanced Functional Materials, 28(12).

By: A. Young, N. Cornwell & M. Daniele

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis

ARCHIVES OF DERMATOLOGICAL RESEARCH, 308(10), 711–721.

By: K. Stover n, T. Fukuyama n, A. Young n, M. Daniele n, R. Oberley*, J. Crapo *, W. Baeumer

co-author countries: United States of America 🇺🇸
author keywords: Superoxide dismutase mimics; BMX-010; BMX-001; Allergic dermatitis; Mice
MeSH headings : Administration, Cutaneous; Administration, Oral; Animals; Cell Line; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dermatitis, Allergic Contact / drug therapy; Disease Models, Animal; Ear; Female; Humans; Infant, Newborn; Inflammation / drug therapy; Inflammation / metabolism; Interleukin-1beta / metabolism; Interleukin-4 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Metalloporphyrins / administration & dosage; Metalloporphyrins / therapeutic use; Mice; Mice, Inbred BALB C; Pruritus / drug therapy; Skin / drug effects; Skin / metabolism; Skin Cream; Superoxide Dismutase / metabolism; Toluene 2,4-Diisocyanate / toxicity; p-Methoxy-N-methylphenethylamine / toxicity
Source: Web Of Science
Added: August 6, 2018