Works (20)
Updated: November 14th, 2024 05:02
2024 article
ABERRANT NLRP3 INFLAMMASOME RESPONSE IN RETT SYNDROME: FROM EX VIVO TO IN VIVO MODELS FOR INVESTIGATING PATHOGENETIC MECHANISMS AND NEW POTENTIAL THERAPEUTIC STRATEGIES
Cordone, V., Pecorelli, A., Frescura, F., Vallese, A., Guiotto, A., Ferrara, F., … Valacchi, G. (2024, June). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 218, pp. 13–14.
Sources: Web Of Science, NC State University Libraries
Added: August 26, 2024
2024 article
ABNORMAL MITOCHONDRION-NLRP3 INFLAMMASOME CROSSTALK IN THE PATHOPHYSIOLOGY OF AUTISM SPECTRUM DISORDER
Vallese, A., Cordone, V., Ferrara, F., Guiotto, A., Gemmo, L., Cervellati, F., … Valacchi, G. (2024, June). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 218, pp. 50–50.
Sources: Web Of Science, NC State University Libraries
Added: August 26, 2024
2024 article
COMPARISON OF POLLUTANT EFFECTS ON CUTANEOUS INFLAMMASOMES ACTIVATION
Ferrara, F., Ivarsson, J., Vallese, A., Guiotto, A., Colella, S., Pecorelli, A., & Valacchi, G. (2024, June). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 218, pp. 27–27.
Sources: Web Of Science, NC State University Libraries
Added: August 26, 2024
2024 article
FIRST EVIDENCE OF REDOX DAMAGE BY INDOOR POLLUTION IN LUNG TISSUE BY THE USE OF 2D AND 3D MODELS
Garces, M., Ferrara, F., Vallese, A., Benedusi, M., Cervellati, F., Magnani, N., … Valacchi, G. (2024, June). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 218, pp. 27–27.
Sources: Web Of Science, NC State University Libraries
Added: August 26, 2024
2024 article
Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage (vol 15, pg 7849, 2024)
Ivarsson, J., Bennett, A., Ferrara, F., Strauch, R., Vallese, A., Iorizzo, M., … Valacchi, G. (2024, October 1). FOOD & FUNCTION, Vol. 10.
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 14, 2024
2024 journal article
NLRP3 inflammasome-mitochondrion loop in autism spectrum disorder
FREE RADICAL BIOLOGY AND MEDICINE, 225, 581–594.
Sources: Web Of Science, NC State University Libraries
Added: November 12, 2024
2023 article
CADMIUM EXPOSURE AFFECTS THE PROGRESSION OF HUMAN METASTATIC MELANOMA BY INDUCING A DEREGULATION OF ANTIOXIDANT CELL RESPONSE
Casoni, A., Benedusi, M., Cervellati, F., Pecorelli, A., Ferrara, F., Vallese, A., & Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 42–43.
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 journal article
Comparison of Pollutant Effects on Cutaneous Inflammasomes Activation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(23).
author keywords: oxinflammation; inflammasome; pollutants; skin
TL;DR:
Among all environmental pollutants, O3, MP, and UV represented the main pollutants affecting cutaneous redox homeostasis; of note, the NLRP1 and NLRP6 inflammasomes were the main ones modulated by these outdoor stressors, suggesting their role as possible molecular targets in preventing skin disorders and the inflammaging events associated with environmental pollutants exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 24, 2023
2023 article
Deregulated NLRP3 inflammasome response due to a constitutive activation of NF-kappa B p65 pro-inflammatory pathway in lymphomonocytes of Rett syndrome patients
Cordone, V., Vallese, A., Pecorelli, A., Guiotto, A., Ferrara, F., Benedusi, M., … Valacchi, G. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S21–S22.
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 article
INFLAMMASOMES REGULATION BY ENVIRONMENTAL POLLUTANTS IN HUMAN SKIN
Ferrara, F., Pecorelli, A., Guiotto, A., Vallese, A., Cordone, V., Benedusi, M., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 38–39.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 article
MITOCHONDRIAL DYSFUNCTION AND NLRP3 INFLAMMASOME ACTIVATION IN AUTISM SPECTRUM DISORDER
Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 20–20.
Sources: Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 journal article
Ox-inflammasome involvement in neuroinflammation
FREE RADICAL BIOLOGY AND MEDICINE, 207, 161–177.
TL;DR:
The current knowledge on the involvement of inflammasome in the main neuropathologies is provided, emphasizing the importance to further clarify the role of oxidative stress in its activation including therole of mitochondria in inflammaome-induced neuroinflammation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023
2023 article
ROLE OF COENZYME Q10 IN MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE DAMAGE IN RETT SYNDROME
Silvestri, S., Marcheggiani, F., Orlando, P., Cirilli, I., Mengarelli, F., Vallese, A., … Tiano, L. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 16–16.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 article
THE POSSIBLE MODULATION OF NRF2 AND NF-KB CROSSTALK BY SULFORAPHANE IN THE PROGRESSION OF HUMAN MELANOMA
Benedusi, M., Canella, R., Vallese, A., Casoni, A., Guerra, M., Rispoli, G., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 57–57.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 article
The pathogenic axis between mitochondrial dysfunction and NLRP3 inflammasome activation in Autism Spectrum Disorder
Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 208, pp. S49–S49.
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 24, 2023
2023 journal article
The role of potassium current in the pulmonary response to environmental oxidative stress
Archives of Biochemistry and Biophysics, 2, 109534.
Contributors: R. Canella *, M. Benedusi *, * , A. Pecorelli *, A. Guiotto *, F. Ferrara *, G. Rispoli *, F. Cervellati *, G. Valacchi *
TL;DR:
The data suggest that O3 is able to inhibit potassium current by targeting BK channel, and can contribute to identify the biomolecular pathway induced by O3 allowing a possible pharmacological intervention against oxidative stress damage in lung tissue.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: September 6, 2023
2022 article
Loss of Scavenger Receptor B1 (SR-B1) in Brain of a Rett Syndrome Mouse Model
Pecorelli, A., Ferrara, F., Guiotto, A., Vallese, A., Cordone, V., Belmonte, G., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 6, 2023
2022 journal article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
REDOX BIOLOGY, 56.
Contributors: F. Ferrara*, V. Cordone *, A. Pecorelli* , M. Benedusi *, E. Pambianchi*, A. Guiotto *, * , F. Cervellati *, G. Valacchi*
author keywords: Inflammasomes; OxInflammation; Proteasome; UBR2; N-end rule pathway
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Air Pollutants; Apoptosis Regulatory Proteins / genetics; Catalase / metabolism; Cytokines / metabolism; Environmental Pollutants; Humans; Hydrogen Peroxide / metabolism; Inflammasomes / metabolism; NLR Proteins / metabolism; Oxidation-Reduction; Ozone / metabolism; Particulate Matter; Reactive Oxygen Species / metabolism; Ubiquitin-Protein Ligases / metabolism; Ubiquitination
TL;DR:
It is reported for the first time that O3, one of the most toxic pollutants, activates the NLRP1 inflammasome in human keratinocytes via oxidative stress mediators as hydrogen peroxide (H2O2) and 4-hydroxy-nonenal (4HNE).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 12, 2022
2022 article
Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation
Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 6, 2023
2022 conference paper
[YIA] Evidence of ferroptosis involvement in Rett syndrome pathogenesis
Free Radical Biology and Medicine, 189, 15.
Source: ORCID
Added: September 6, 2023
Employment
Updated: November 23rd, 2023 11:00
2021 - present
University of Ferrara Ferrara, IT
PhD student
2023 - 2023
North Carolina State University Kannapolis, US
Research scholar
Education
Updated: February 18th, 2023 09:12
2019 - 2021
University of L'Aquila L’Aquila, IT
Biology of health and nutrition
2015 - 2018
University of L'Aquila L’Aquila, IT
Biological science
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