Works (3)

Updated: July 1st, 2023 21:21

2022 article

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Wang, Z., Popowski, K. D., Zhu, D., Juan Abad, B. L., Wang, X., Liu, M., … Cheng, K. (2022, July 4). Nature Biomedical Engineering, Vol. 7.

By: Z. Wang n, K. Popowski n, D. Zhu n, B. Juan Abad n, X. Wang n, M. Liu n, H. Lutz n, N. Naeyer* ...

MeSH headings : Animals; Antibodies, Neutralizing; CD8-Positive T-Lymphocytes; COVID-19 / prevention & control; COVID-19 Vaccines; Exosomes; Humans; Mice; Mice, Inbred BALB C; SARS-CoV-2; Viral Vaccines
topics (OpenAlex): SARS-CoV-2 and COVID-19 Research; Extracellular vesicles in disease; Inhalation and Respiratory Drug Delivery
TL;DR: The design and preclinical testing of an inhalable virus-like-particle as a COVID-19 vaccine that, after lyophilisation, is stable at room temperature for over three months and elicits systemic and mucosal immune responses in small animals is reported. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 11, 2022

2021 article

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

Mei, X., Zhu, D., Li, J., Huang, K., Hu, S., Li, Z., … Cheng, K. (2021, November 1). Med, Vol. 11, pp. 1253–1268.e4.

By: X. Mei n, D. Zhu n, J. Li n, K. Huang n, S. Hu n, Z. Li n, B. Juan Abad n, K. Cheng n

Contributors: X. Mei n, D. Zhu n, J. Li n, K. Huang n, S. Hu n, Z. Li n, B. Juan Abad n, K. Cheng n

MeSH headings : Animals; Cell- and Tissue-Based Therapy; Heart; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells; Myocardial Infarction / surgery; Rats; Swine
topics (OpenAlex): Nerve injury and regeneration; Tissue Engineering and Regenerative Medicine; Electrospun Nanofibers in Biomedical Applications
TL;DR: A fluid-driven heart pouch with a memory-shaped microfabricated lattice structure inspired by origami allowed minimally invasive delivery of the pouch to the heart with two small incisions and can be refilled multiple times with the therapeutic of choice. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 3, 2021

2021 article

Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies

Liu, M., Juan Abad, B. L., & Cheng, K. (2021, April 5). Advanced Drug Delivery Reviews.

By: M. Liu n, B. Juan Abad n & K. Cheng n

author keywords: Cardiac fibrosis; Cardiac fibroblast; Myofibroblasts; Myocardial remodeling; Reprogramming; Drug delivery systems
MeSH headings : Animals; Drug Delivery Systems; Extracellular Matrix / metabolism; Extracellular Matrix / pathology; Fibrosis / metabolism; Fibrosis / pathology; Humans; Myocardium / metabolism; Myocardium / pathology; Myofibroblasts / metabolism; Myofibroblasts / pathology; Pharmaceutical Preparations / chemistry
topics (OpenAlex): Tissue Engineering and Regenerative Medicine; Cardiac Fibrosis and Remodeling; Cardiac Structural Anomalies and Repair
TL;DR: This review will outline the progress of cardiac fibrosis and its contributions to the heart failure, and shed light on the role of myoFbs in the regulation of adverse remodeling. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 28, 2021

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