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Works (41)
Updated: April 5th, 2024 00:15
2017 journal article
Co-sensitization and cross-reactivity between related and unrelated food allergens in dogs - a serological study
Veterinary Dermatology, 28(1), 31-.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Therapeutic anti-IgE monoclonal antibody single chain variable fragment (scFv) safety and immunomodulatory effects after one time injection in four dogs
VETERINARY DERMATOLOGY, 28(1), 52-+.
MeSH headings : Animals; Antibodies, Anti-Idiotypic / administration & dosage; Antibodies, Anti-Idiotypic / adverse effects; Antibodies, Anti-Idiotypic / immunology; Antibodies, Anti-Idiotypic / therapeutic use; Antibodies, Monoclonal / adverse effects; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / immunology; Dogs; Epitopes; Female; Immunoglobulin E / immunology; Immunologic Factors / administration & dosage; Immunologic Factors / adverse effects; Immunologic Factors / immunology; Immunologic Factors / therapeutic use; Injections, Subcutaneous; Male
TL;DR:
A single injection of monomeric, pegylated scFv with high affinity for dog IgE was demonstrated to be safe and marked reduction in IgE‐bearing lymphocytes and granulocytes accompanied by reduced “free” plasma IgE level in two of four dogs is analogous to omalizumab in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
A study for characterization of IgE-mediated cutaneous immediate and late-phase reactions in non-allergic domestic cats
Veterinary Immunology and Immunopathology, 159(1-2), 41–49.
author keywords: Atopic dermatitis; Cat; Cutaneous immediate-reaction; Cutaneous late-phase reaction; Allergic dermatitis; IgE
MeSH headings : Animals; Antibodies, Anti-Idiotypic / administration & dosage; Antibodies, Anti-Idiotypic / immunology; Biopsy / veterinary; Cat Diseases / immunology; Cats; Cell Count / veterinary; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Female; Immunohistochemistry / veterinary; Injections, Intradermal / veterinary; Least-Squares Analysis; Mast Cells / immunology; Pilot Projects
TL;DR:
The gross and cellular response to injection of anti-IgE in the skin of healthy, non-allergic cats is document and a possible role for IgE is supported in the development of feline allergic dermatitis is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
Characterization of IgE-mediated cutaneous immediate and late-phase reactions in nonallergic horses
AMERICAN JOURNAL OF VETERINARY RESEARCH, 75(7), 633–641.
MeSH headings : Animals; Antibodies, Anti-Idiotypic / immunology; Dermatitis / immunology; Dermatitis / veterinary; Eosinophils / immunology; Female; Horse Diseases / chemically induced; Horse Diseases / immunology; Horse Diseases / pathology; Horses / immunology; Immunoglobulin E / immunology; Inflammation / chemically induced; Inflammation / pathology; Inflammation / veterinary; Injections, Intradermal / veterinary; Intradermal Tests / veterinary; Leukocyte Count / veterinary; Male; Neutrophils / immunology; Rabbits; Skin Diseases / chemically induced; Skin Diseases / immunology; Skin Diseases / veterinary; Skin Tests / veterinary
TL;DR:
Injection of anti-IgE antibodies was associated with the development of gross and microscopic inflammation characterized by mast cell degranulation and accumulation of inflammatory cells, particularly eosinophils and neutrophils, which appeared to be similar to that of horses with naturally developing allergic skin disease.
(via Semantic Scholar)
open access via digitalcommons.lsu.edu (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Effects of pentoxifylline on immediate and late-phase cutaneous reactions in response to anti-immunoglobulin E antibodies in clinically normal dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 75(2), 152–160.
MeSH headings : Administration, Cutaneous; Animals; Antibodies, Anti-Idiotypic / adverse effects; Dog Diseases / chemically induced; Dog Diseases / drug therapy; Dogs; Free Radical Scavengers / therapeutic use; Immunoglobulin E / immunology; Inflammation / drug therapy; Inflammation / veterinary; Injections, Intradermal / veterinary; Intradermal Tests / veterinary; Pentoxifylline / therapeutic use; Skin Diseases / chemically induced; Skin Diseases / drug therapy; Skin Diseases / veterinary; Skin Tests / veterinary
TL;DR:
In clinically normal dogs, pentoxifylline effectively impaired late-phase reactions but not immediate reactions at sites of intradermal injection of IgE-specific antibodies by inhibiting mast cell degranulation and recruitment of cutaneous inflammatory cells, especially eosinophils.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 chapter
Canine IgE
In C. Noli, A. Foster, & W. RosenKrantz (Eds.), Veterinary Allergy. Wiley-Blackwell.
Ed(s): C. Noli, A. Foster & W. RosenKrantz
Source: NC State University Libraries
Added: July 28, 2019
2013 chapter
Serum Anti-Staphylococcus PseudintermediusIge and Igg Antibodies in Dogs with Atopic Dermatitis and Nonatopic Dogs
In Advances in Veterinary Dermatology (pp. 19–24).
Source: Crossref
Added: July 28, 2019
2013 journal article
Serum anti-Staphylococcus pseudintermedius IgE and IgG antibodies in dogs with atopic dermatitis and nonatopic dogs
Veterinary Dermatology, 24(1).
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
A comparison of the clinical manifestations of feeding whole and hydrolysed chicken to dogs with hypersensitivity to the native protein
VETERINARY DERMATOLOGY, 21(4), 358–366.
MeSH headings : Animal Feed; Animals; Chickens; Cross-Over Studies; Dermatitis / immunology; Dermatitis / pathology; Dermatitis / veterinary; Diet; Dog Diseases / immunology; Dogs; Double-Blind Method; Female; Food Hypersensitivity / immunology; Food Hypersensitivity / veterinary; Hydrolysis; Male; Meat / adverse effects; Proteins / immunology
TL;DR:
Assessment of a CADESI (Canine Atopic Dermatitis Extent and Severity Index) score and pruritus were performed throughout the entire study, and combined in a global score (GS).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 review
Canine immunoglobulin E
[Review of ]. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 132(1), 7–12.
author keywords: Canine; Immunoglobulin E; Disease; Diagnosis; Comparative
MeSH headings : Animals; B-Lymphocytes / immunology; B-Lymphocytes / metabolism; Dendritic Cells / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dog Diseases / therapy; Dogs; Humans; Hypersensitivity / blood; Hypersensitivity / immunology; Hypersensitivity / therapy; Hypersensitivity / veterinary; Immunoglobulin E / biosynthesis; Immunoglobulin E / blood; Immunoglobulin E / genetics; Immunoglobulin E / immunology; Immunotherapy
TL;DR:
It is clear that research on IgE in spontaneously allergic dogs offers many opportunities to explore novel immunotherapeutic approaches to the control of allergic disease that will benefit both dogs and humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Levels of house dust mite-specific serum immunoglobulin E (IgE) in different cat populations using a monoclonal based anti-IgE enzyme-linked immunosorbent assay
VETERINARY DERMATOLOGY, 20(5-6), 562–568.
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Antigens, Dermatophagoides / immunology; Cat Diseases / immunology; Cats; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Immunoglobulin E / blood; Male; Pyroglyphidae / immunology
TL;DR:
The results suggest that DF in its native form may be a significant allergen in cats with allergic dermatitis, however, the clinical relevance of these reactions remains to be proven.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Epicutaneous sensitization with Dermatophagoides farinae induces generalized allergic dermatitis and elevated mite-specific immunoglobulin E levels in a canine model of atopic dermatitis
CLINICAL AND EXPERIMENTAL ALLERGY, 38(4), 667–679.
Contributors: C. Pucheu-Haston n, H. Jackson n, T. Olivry n , S. Dunston n & n
author keywords: allergy; animal models; atopic dermatitis; atopy; Dermatophagoides farinae; dogs; skin (dermatology) immunology
MeSH headings : Animals; Dermatitis, Atopic / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatophagoides farinae / immunology; Disease Models, Animal; Dogs; Female; Immunoglobulin E / blood; Immunoglobulin G / blood; Male; Pruritus / blood; Pruritus / immunology; Pruritus / pathology; Skin Tests
TL;DR:
Background Atopic dermatitis is a cutaneous hypersensitivity associated with elevated levels of antigen‐specific IgE, commonly to house dust mites (HDMs), and it remains controversial as to whether sensitization and clinical disease are induced by cutaneous exposure to HDM.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 patent
Immunoglobulin E detection in mammalian species
Source: NC State University Libraries
Added: August 6, 2018
2007 journal article
A novel gene from Brugia sp that encodes a cytotoxic fatty acid binding protein allergen recognized by canine monoclonal IgE and serum IgE from infected dogs
JOURNAL OF PARASITOLOGY, 93(6), 1378–1387.
MeSH headings : Allergens / chemistry; Allergens / genetics; Allergens / immunology; Amino Acid Sequence; Animals; Antibodies, Helminth / immunology; Antibodies, Monoclonal / immunology; Antigens, Helminth / chemistry; Antigens, Helminth / genetics; Antigens, Helminth / immunology; B-Lymphocytes / immunology; Base Sequence; Blotting, Western; Brugia / genetics; Brugia / immunology; Brugia pahangi / genetics; Brugia pahangi / immunology; Disease Models, Animal; Dogs; Epitopes / immunology; Fatty Acid-Binding Proteins / chemistry; Fatty Acid-Binding Proteins / genetics; Fatty Acid-Binding Proteins / immunology; Female; Filariasis / immunology; Filariasis / parasitology; Gerbillinae; Glutathione Transferase / genetics; Glutathione Transferase / immunology; Immunoglobulin E / blood; Immunoglobulin E / immunology; Male; Molecular Sequence Data; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology; Sequence Homology
TL;DR:
This 35-kDa protein seems to be highly conserved in different stages and species of filarids, and it represents a previously unknown allergen that is possibly involved in the pathogenesis of filarial disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Lack of detection of circulating skin-specific IgE autoantibodies in dogs with moderate or severe atopic dermatitis
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 122(1-2), 182–187.
Contributors: T. Olivry n , S. Dunston n, K. Pluchino n, K. Porter n & n
author keywords: allergy; atopy; autoimmunity; canine; IgE; skin
MeSH headings : Animals; Autoantibodies / blood; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dogs; Female; Fluorescent Antibody Technique, Indirect; Immunoblotting; Immunoglobulin E / blood; Male; Skin / immunology
TL;DR:
Either IgE autoreactivity is not associated with moderate to severe AD in dogs, or the methods employed herein were not sensitive enough to permit IgE autoantibody detection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 patent
Immunoglobulin E detection in mammalian species
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
A canine model of cutaneous late-phase reactions: prednisolone inhibition of cellular and cytokine responses
IMMUNOLOGY, 117(2), 177–187.
Contributors: C. Pucheu-Haston n, D. Shuster, T. Olivry n , P. Brianceau, P. Lockwood, T. McClanahan, R. De Waal Malefyt, J. Mattson, n
author keywords: animal models/studies; cows/pigs/horses/cats/dogs; allergy; atopy; basophils/mast cells; skin (dermatology) immunology/disease
MeSH headings : Animals; Anti-Inflammatory Agents / therapeutic use; Antibodies, Anti-Idiotypic / immunology; Chemotaxis, Leukocyte / drug effects; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatitis, Atopic / prevention & control; Disease Models, Animal; Dogs; Eosinophils / immunology; Female; Gene Expression Regulation / drug effects; Immunoglobulin E / immunology; Immunophenotyping; Injections, Intradermal; Male; Mast Cells / pathology; Neutrophils / immunology; Polymerase Chain Reaction / methods; Prednisolone / therapeutic use; Skin / immunology
TL;DR:
The data document the cytokine and chemokine responses to anti‐IgE injection in canine skin, and they demonstrate the ability of the model to characterize the anti‐inflammatory effects of a known therapeutic agent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Effects of routine prophylactic vaccination or administration of aluminum adjuvant alone on allergen-specific serum IgE and IgG responses in allergic dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 66(9), 1572–1577.
MeSH headings : Adjuvants, Immunologic / pharmacology; Aluminum; Analysis of Variance; Animals; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Food Hypersensitivity / immunology; Food Hypersensitivity / veterinary; Immunoglobulin E / blood; Immunoglobulin G / blood; Time Factors; Vaccination / veterinary; Zea mays / adverse effects
TL;DR:
Allergen-specific IgE and IgG concentrations increase after prophylactic vaccination in allergic dogs but not in clinically normal dogs, while control dogs did not have a significant change in serum immunoglobulin concentrations after vaccination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 conference paper
Mechanism of lesion formation in canine atopic dermatitis: 2004 hypothesis
In A. P. F. A. Hillier & K. W. Kwochka (Eds.), Advances in veterinary dermatology: proceedings of the fifth World Congress of Veterinary Dermatology, Vienna, Austria, 25-28 August 2004 (Vol. 5, pp. 10–16). Oxford : Blackwell Publishing.
Ed(s): A. A. Hillier & K. Kwochka
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Spontaneous, IgE-associated food allergy in dogs as a model of human peanut allergy
Journal of Allergy and Clinical Immunology, 115(2), S34.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2003 chapter
Canine Immune System
In Animal Models of Human Inflammatory Skin Diseases (pp. 79–89).
Source: Crossref
Added: July 28, 2019
2003 journal article
Evaluation of the clinical and allergen specific serum immunoglobulin E responses to oral challenge with cornstarch, corn, soy and a soy hydrolysate diet in dogs with spontaneous food allergy
VETERINARY DERMATOLOGY, 14(4), 181–187.
author keywords: dog; food allergy; hydrolysed protein; IgE; intradermal test
MeSH headings : Animal Feed; Animals; Antigens; Diet; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Female; Food Hypersensitivity / diagnosis; Food Hypersensitivity / immunology; Food Hypersensitivity / veterinary; Immunoglobulin E / blood; Immunoglobulin E / immunology; Intradermal Tests / standards; Intradermal Tests / veterinary; Male; Predictive Value of Tests; Soybean Proteins / immunology; Soybeans / immunology; Zea mays / immunology
TL;DR:
Although increases in soy and corn-specific serum IgE concentrations were measured in individual dogs post challenge they were not statistically significant and could not be used to predict clinical hypersensitivity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Management of drug-resistant cyathostominosis on a breeding farm in central North Carolina
EQUINE VETERINARY JOURNAL, 35(3), 246–251.
author keywords: horse; cyathostome; resistant; benzimidazole; pyrantel
MeSH headings : Animals; Antinematodal Agents / pharmacology; Antinematodal Agents / therapeutic use; Drug Resistance; Drug Resistance, Multiple; Feces / parasitology; Female; Fenbendazole / pharmacology; Fenbendazole / therapeutic use; Horses; Intestinal Diseases, Parasitic / drug therapy; Intestinal Diseases, Parasitic / parasitology; Intestinal Diseases, Parasitic / veterinary; Ivermectin / pharmacology; Ivermectin / therapeutic use; North Carolina; Parasite Egg Count / veterinary; Parasitic Sensitivity Tests / veterinary; Pyrantel / pharmacology; Pyrantel / therapeutic use; Strongyle Infections, Equine / drug therapy; Strongyle Infections, Equine / parasitology; Strongyloidea / drug effects; Treatment Outcome
TL;DR:
Targeted ivermectin treatment may be an economically viable method of managing multiple drug resistant cyathostome infection in consecutive foal crops and should be monitored closely for development of resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Synthetic IgE peptide vaccine for immunotherapy of allergy
VACCINE, 21(15), 1580–1590.
author keywords: IgE; peptide; immunotherapy
MeSH headings : Amino Acid Sequence; Animals; Binding Sites, Antibody; Desensitization, Immunologic / methods; Dogs; Drug Delivery Systems / methods; Guinea Pigs; Humans; Hypersensitivity / immunology; Hypersensitivity / prevention & control; Immunoglobulin E / immunology; Immunoglobulin E / metabolism; Immunoglobulin E / therapeutic use; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Receptors, IgE / metabolism; Swine; Vaccines, Subunit / therapeutic use; Vaccines, Synthetic / therapeutic use
TL;DR:
An immunotherapeutic vaccine for allergy was produced by designing IgE-based synthetic peptide immunogens and selecting them for functional immunogenicity and inducing polyclonal site-specific anti-IgE antibodies that obstruct binding to Fc epsilon RI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Assessment of protein allergenicity on the basis of immune reactivity: Animal models
Environmental Health Perspectives, 111(8), 1125–1130.
MeSH headings : Administration, Oral; Animals; Dietary Proteins / adverse effects; Dietary Proteins / immunology; Disease Models, Animal; Dogs; Food Hypersensitivity / physiopathology; Food Hypersensitivity / veterinary; Humans; Infusions, Parenteral; Mice; Mice, Inbred BALB C; Peanut Hypersensitivity / immunology; Peanut Hypersensitivity / physiopathology; Rats; Risk Assessment; Swine
TL;DR:
Progress made in the design and evaluation of models in the rat, the mouse, the dog and in swine is reviewed and discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Evaluation of a spontaneous canine model of IgE mediated food hypersensitivity: dynamic changes in serum, faecal and allergen-specific IgE relative to dietary change
Comparative Medicine, 52, 316–321.
Source: NC State University Libraries
Added: July 11, 2019
2002 journal article
Evaluation of a spontaneous canine model of immunoglobulin E- mediated food hypersensitivity: Dynamic changes in serum and fecal allergen-specific immunoglobulin E values relative to dietary change
Comparative Medicine, 52(4), 316–321.
Source: NC State University Libraries
Added: August 6, 2018
2002 article
Heterobilharzia americana infection in a dog
Flowers, JR, Hammerberg, B., Wood, S. L., Malarkey, D. E., Dam, G. J., Levy, M. G., & McLawhorn, L. D. (2002, January 15). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 220, pp. 193–196.
MeSH headings : Animals; Anthelmintics / therapeutic use; Antigens, Helminth / blood; Antigens, Helminth / immunology; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Feces / parasitology; Male; Parasite Egg Count / veterinary; Praziquantel / therapeutic use; Schistosomatidae / isolation & purification; Trematode Infections / diagnosis; Trematode Infections / drug therapy; Trematode Infections / parasitology; Trematode Infections / veterinary
TL;DR:
It is suggested that heterobilharziasis is underdiagnosed in dogs that have contact with water frequented by raccoons and inappropriate diagnostic procedures can foil accurate detection of this parasitic disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
IgE is present on peripheral blood monocytes and B cells in normal dogs and dogs with atopic dermatitis but there is no correlation with serum IgE concentrations
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 85(3-4), 225–232.
author keywords: IgE; canine PBMCs; canine atopic dermatitis
MeSH headings : Animals; Antigens, CD1 / blood; B-Lymphocytes / immunology; B-Lymphocytes / metabolism; Dermatitis, Atopic / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / blood; Dog Diseases / immunology; Dogs / blood; Dogs / immunology; Female; Flow Cytometry / veterinary; Glycoproteins / blood; Immunoglobulin E / blood; Immunoglobulin E / immunology; Lipopolysaccharide Receptors / blood; Male; Monocytes / immunology; Monocytes / metabolism; Receptors, Complement 3d / blood
TL;DR:
Canine AD is associated with more variability in circulating monocyte numbers and lower numbers of monocytes expressing IgE than control dogs, and there is no correlation between circulating and cell bound IgE in any of the leucocyte populations studied.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Skin mast cell histamine release following stem cell factor and high-affinity immunoglobulin E receptor cross-linking in dogs with atopic dermatitis
VETERINARY DERMATOLOGY, 12(6), 339–346.
author keywords: atopic dermatitis; histamine; mast cell; stem cell factor
MeSH headings : Animals; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dogs / immunology; Enzyme-Linked Immunosorbent Assay / veterinary; Histamine Release / drug effects; Immunoglobulin E / immunology; Immunohistochemistry / veterinary; Injections, Intradermal / veterinary; Mast Cells / drug effects; Mast Cells / immunology; Mast Cells / metabolism; Receptors, IgE / drug effects; Skin / cytology; Stem Cell Factor / pharmacology
TL;DR:
Dermal SCF secretion could potentiate histamine release following IgE receptor cross-linking and thus, could be one of the explanations for the inherent mast cell hyperexcitability observed in canine atopic dermatitis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2000 article
Food hypersensitivity reactions in Soft Coated Wheaten Terriers with protein-losing enteropathy or protein-losing nephropathy or both: Gastroscopic food sensitivity testing, dietary provocation, and fecal immunoglobulin E
JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 60–67.
author keywords: food allergy; glomerulonephritis; inflammatory bowel disease
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Identification of a collectin-like protein in pig serum that binds a component in perienteric fluid from Ascaris suum
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 23(2), 113–124.
author keywords: collectin; Ascaris suum; pig; serum; polysaccharide
MeSH headings : Animals; Antibodies, Monoclonal; Ascaris suum / immunology; Carrier Proteins / blood; Carrier Proteins / immunology; Collectins; Electrophoresis, Polyacrylamide Gel / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Mice; Mice, Inbred BALB C; Swine; Swine Diseases / blood; Swine Diseases / immunology
TL;DR:
This is the first report of a porcine CLP and the binding of a CLP to components of the common nematode Ascaris suum.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Natural killer cell-dependent immunoglobulin G2a anti-bovine serum albumin (BSA) response elicited by high molecular weight dextran-BSA conjugates associated with dextran-mediated macrophage-natural killer cell interaction
IMMUNOLOGY, 101(4), 474–483.
MeSH headings : Adjuvants, Immunologic; Animals; Cell Communication / immunology; Cell Culture Techniques; Dextrans / immunology; Dose-Response Relationship, Immunologic; Immunization / methods; Immunoglobulin G / biosynthesis; Interferon-gamma / biosynthesis; Interleukin-12 / biosynthesis; Killer Cells, Natural / immunology; Macrophages / immunology; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Serum Albumin, Bovine / immunology; Spleen / immunology
TL;DR:
The results indicate an IL‐12‐dependent positive feedback interaction between NK cells and Mφ that supports a NK cell/IFN‐γ‐dependent mechanism for enhancement of anti‐BSA IgG2a antibody responses in mice immunized with HMW‐DEX–BSA protein conjugates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Association of elevated lymph node cell release of histamine and tumor necrosis factor with genetic predisposition to limb edema formation in dogs infected with Brugia pahangi
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 58(6), 695–704.
MeSH headings : Animals; Biopsy / veterinary; Brugia pahangi / physiology; Cells, Cultured; Dinoprostone / metabolism; Dog Diseases / etiology; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Female; Filariasis / complications; Filariasis / metabolism; Filariasis / veterinary; Histamine / metabolism; Immunohistochemistry; Lymph Nodes / metabolism; Lymph Nodes / pathology; Lymphedema / etiology; Lymphedema / genetics; Lymphedema / veterinary; Lymphocyte Activation; Male; Pedigree; Tumor Necrosis Factor-alpha / metabolism
TL;DR:
Lymph node cells from a litter of dogs selectively bred with a high incidence of edema formation demonstrated spontaneously released histamine and prostaglandin E2 levels higher than those of closely related nonedema-forming dogs and/or control dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Case studies in organ transplantation
Ag Bioethics Forum, 10(2), 2–6.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Auto IgG anti-IgE and IgG x IgE immune complex presence and effects on ELISA-based quantitation of IgE in canine atopic dermatitis, demodectic acariasis and helminthiasis.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 60(1-2), 33–46.
Contributors: n, D. Bevier n, D. DeBoer *, T. Olivry n , S. Orton n, D. Gebhard n, S. Vaden n
author keywords: auto anti-IgE; ELISA; atopic; helminth; immune complexes; demodectic acariasis
MeSH headings : Animals; Antibodies, Anti-Idiotypic / blood; Antigen-Antibody Complex / blood; Ascariasis / immunology; Ascariasis / veterinary; Autoantibodies / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay; Helminthiasis, Animal / immunology; Immunoglobulin E / blood; Immunoglobulin G / blood
TL;DR:
The increase in detectable IgG anti-IgE after heating sera indicates that IgG x IgE immune complexes are normally present in most dogs; however, the increase over uncomplexed IgG against IgE was most pronounced in dogs manifesting atopic dermatitis and demodectic acariasis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
1996 journal article
Inhibition by platelets of in vitro blastogenic responses of canine PBMC by a PAF-dependent mechanism
Veterinary Immunology and Immunopathology, 52(3), 135–145.
author keywords: platelets; dogs; platelet activating factor; lymphocyte; blastogenesis
MeSH headings : Animals; Biopsy; Blood Platelets / parasitology; Blood Platelets / physiology; Centrifugation, Density Gradient; Dogs; Female; Filariasis / immunology; Leukocyte Count; Leukocytes, Mononuclear / physiology; Lymph Nodes / cytology; Lymphocyte Activation; Male; Phytohemagglutinins / pharmacology; Platelet Membrane Glycoproteins / antagonists & inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled
TL;DR:
It was shown that PB MC purified on Ficoll gradients alone are contaminated with platelets and proliferate weakly compared with platelet-free PBMC purified on an additional Percoll gradient, suggesting that PAF is likely to be involved in the inhibition of in vitro proliferative responses of platelets-contaminated canine PBMC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, Web Of Science
Added: August 6, 2018
1995 journal article
Canine IgE monoclonal antibody specific for a filarial antigen: production by a canine X murine heterohybridoma using B cells from a clinically affected lymph node
Immunology, 85, 429–434.
Source: NC State University Libraries
Added: July 28, 2019
1993 journal article
Modulation of cellular and humoral immunity, and disease manifestation during onset of patency in Brugia pahangi-infected dogs
Immunology, 79, 658–666.
Source: NC State University Libraries
Added: July 11, 2019
1991 journal article
Inhibition of antigen-driven proliferative responses and enhancement of antibody production during infection with Brugia pahangi
Journal of Immunology, 147, 1007–1013.
Source: NC State University Libraries
Added: July 28, 2019
1989 journal article
Protective immunity against Brugia malayi infective larvae in mice. II. Induction by a T cell-dependent antigen isolated by monoclonal antibody affinity chromatography and SDS-PAGE
Journal of Immunology, 143(12), 4201.
Source: NC State University Libraries
Added: August 6, 2018
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