Beth Hawkins

Works (7)

Updated: July 5th, 2023 16:01

2014 article

Bridging the Gap From Screening Assays to Estrogenic Effects in Fish: Potential Roles of Multiple Estrogen Receptor Subtypes

Yost, E. E., Pow, C. L., Hawkins, M. B., & Kullman, S. W. (2014, January 14). Environmental Science & Technology.

By: E. Yost n, C. Pow  n, M. Hawkins n & S. Kullman n 

MeSH headings : Animals; Estrogen Receptor alpha / physiology; Estrogen Receptor beta / physiology; Estrogens / pharmacology; Humans; Liver / metabolism; Male; Oryzias; Polymerase Chain Reaction; Vitellogenins / metabolism; Water Pollutants, Chemical / pharmacology
topics (OpenAlex): Reproductive biology and impacts on aquatic species; Estrogen and related hormone effects; Effects and risks of endocrine disrupting chemicals
TL;DR: Results support emerging evidence that ERβ subtypes are critically involved in the teleost estrogenic response, with the ERα:ERβ ratio being of particular importance. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2014 article

Functional Diversification of Vitamin D Receptor Paralogs in Teleost Fish After a Whole Genome Duplication Event

Kollitz, E. M., Hawkins, M. B., Whitfield, G. K., & Kullman, S. W. (2014, October 3). Endocrinology.

By: E. Kollitz n, M. Hawkins n, G. Whitfield* & S. Kullman n 

MeSH headings : Animals; Calcitriol / metabolism; Evolution, Molecular; Fish Proteins / genetics; Fish Proteins / metabolism; Gene Duplication; Genome; Nuclear Receptor Coactivators / metabolism; Oryzias; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Retinoid X Receptors / metabolism; Zebrafish
topics (OpenAlex): Animal Genetics and Reproduction; Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities; Vitamin D Research Studies
TL;DR: The results imply that functional differences between VDRα and VDRβ occurred early in teleost evolution because they are conserved between distantly related species, and suggest that the observed differences may be associated with differential protein-protein interactions between the VDR paralogs and coactivators. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2011 article

Sexual Phenotype Differences in zic2 mRNA Abundance in the Preoptic Area of a Protogynous Teleost, Thalassoma bifasciatum

McCaffrey, K., Hawkins, M. B., & Godwin, J. (2011, August 3). PLoS ONE, Vol. 6.

By: K. McCaffrey n, M. Hawkins n & J. Godwin n 

MeSH headings : Animals; Female; Fishes / genetics; Fishes / metabolism; Hypothalamus / metabolism; Male; RNA, Messenger / genetics; Sexual Behavior, Animal / physiology; Transcription Factors / genetics
topics (OpenAlex): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities; Animal Behavior and Reproduction; Reproductive biology and impacts on aquatic species
TL;DR: Sexual phenotype differences in abundances of zic2 mRNA in the preoptic area of the hypothalamus, a region strongly implicated in sexual behavior and function, in an adult teleost, Thalassoma bifasciatum is described. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

Aromatase immunoreactivity in the bluehead wrasse brain, Thalassoma bifasciatum: Immunolocalization and co-regionalization with arginine vasotocin and tyrosine hydroxylase

Marsh, K. E., Creutz, L. M., Hawkins, M. B., & Godwin, J. (2006, October 12). Brain Research, Vol. 1126, pp. 91–101.

By: K. Marsh n, L. Creutz n, M. Hawkins n & J. Godwin n 

author keywords: aromatase; arginine vasotocin; dopamine; estrogen; teleost; hypothalamus
MeSH headings : Aggression / physiology; Animals; Aromatase / metabolism; Brain / anatomy & histology; Brain / metabolism; Brain Mapping; Dopamine / biosynthesis; Estrogens / biosynthesis; Female; Gonads / metabolism; Immunohistochemistry; Male; Neuroglia / metabolism; Neurons / metabolism; Perciformes / anatomy & histology; Perciformes / metabolism; Reproduction / physiology; Sex Differentiation / physiology; Sexual Behavior, Animal / physiology; Species Specificity; Tyrosine 3-Monooxygenase / metabolism; Vasotocin / metabolism
topics (OpenAlex): Reproductive biology and impacts on aquatic species; Reproductive System and Pregnancy; Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
TL;DR: The presence of aromatase in brain regions important in the regulation of sexual and aggressive behavior suggests that local estrogen synthesis could regulate sex change through effects on signaling systems that subserve reproductive behavior and function. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 article

The distributions of the duplicate oestrogen receptors ER-βa and ER-βb in the forebrain of the Atlantic croaker (Micropogonias undulatus): evidence for subfunctionalization after gene duplication

Hawkins, M. B., Godwin, J., Crews, D., & Thomas, P. (2005, March 22). Proceedings of the Royal Society B Biological Sciences, Vol. 272, pp. 633–641.

By: M. Hawkins*, J. Godwin n , D. Crews * & P. Thomas

author keywords: oestrogen receptor; gene duplication; teleostfishes; neuroendocrine regulation; hypothalamus; brain
MeSH headings : Animals; Estrogen Receptor beta / genetics; Estrogen Receptor beta / metabolism; Evolution, Molecular; Female; Gene Expression Profiling; Genes, Duplicate / genetics; In Situ Hybridization; Molecular Probe Techniques; Perciformes / metabolism; Prosencephalon / metabolism; RNA, Messenger / metabolism; Texas
topics (OpenAlex): Reproductive biology and impacts on aquatic species; Estrogen and related hormone effects; Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
TL;DR: The distribution of the three ER mRNAs in the hypothalamus and cerebellum of the Atlantic croaker is described to address two issues: the specific functions of multiple ERs in the neuroendocrine system and the evolution and fate of duplicated genes. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 article

The unusual binding properties of the third distinct teleost estrogen receptor subtype ER beta a are accompanied by highly conserved amino acid changes in the ligand binding domain

Beth Hawkins

MeSH headings : Amino Acid Sequence; Animals; Binding, Competitive; Conserved Sequence; Estrogen Antagonists / metabolism; Estrogen Receptor beta; Estrogens / chemical synthesis; Estrogens / metabolism; Fishes / genetics; Fishes / metabolism; Ligands; Mutagenesis, Site-Directed; Protein Isoforms / genetics; Protein Isoforms / metabolism; Protein Structure, Tertiary / genetics; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism
topics (OpenAlex):
Source: NC State University Libraries
Added: August 6, 2018

2000 article

Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts

Hawkins, M. B., Thornton, J. W., Crews, D., Skipper, J. K., Dotte, A., & Thomas, P. (2000, September 26). Proceedings of the National Academy of Sciences.

By: M. Hawkins*, J. Thornton, D. Crews, J. Skipper, A. Dotte & P. Thomas

MeSH headings : Amino Acid Sequence; Animals; Fishes / metabolism; Ligands; Molecular Sequence Data; Phylogeny; Receptors, Estrogen / analysis; Receptors, Estrogen / classification; Receptors, Estrogen / genetics; Sequence Alignment; Signal Transduction
topics (OpenAlex): Estrogen and related hormone effects; Reproductive biology and impacts on aquatic species; Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
TL;DR: Three distinct estrogen receptor subtypes are described: ERalpha, ERbeta, and a unique type, ERgamma, cloned from a teleost fish, the Atlantic croaker Micropogonias undulatus; the first identification of a third type of classical ER in vertebrate species. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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