Barry Hedgespeth

College of Veterinary Medicine

Works (6)

Updated: July 13th, 2023 21:17
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2023 journal article

The exon-skipping oligonucleotide, KitStop, depletes tissue-resident mast cells in vivo to ameliorate anaphylaxis

FRONTIERS IN IMMUNOLOGY, 14.

By: B. Hedgespeth n, D. Snider n, K. Bitting n & G. Cruse n 

author keywords: mast cell (MC); anaphylaxis; KIT; exon skipping; mast cell depletion
MeSH headings : Mice; Animals; Mast Cells; Anaphylaxis / genetics; Anaphylaxis / therapy; Mastocytosis; Allergens
Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 article

Identification of redundancy between human Fc epsilon RI beta and MS4A6A proteins points toward additional complex mechanisms for Fc epsilon RI trafficking and signaling

Bitting, K., Hedgespeth, B., Ehrhardt-Humbert, L. C., Arthur, G. K., Schubert, A. G., Bradding, P., … Cruse, G. (2022, December 7). ALLERGY, Vol. 12.

By: K. Bitting n, B. Hedgespeth n, L. Ehrhardt-Humbert n, G. Arthur n, A. Schubert n, P. Bradding *, S. Tilley*, G. Cruse n 

author keywords: asthma; IgE; mast cells
MeSH headings : Animals; Humans; Mice; Basophils / metabolism; Cell Degranulation; Exons; Hypersensitivity / metabolism; Mast Cells / metabolism; Receptors, IgE / genetics; Receptors, IgE / metabolism; Signal Transduction
Sources: Web Of Science, ORCID
Added: November 25, 2022

2021 journal article

A novel missense mutation of the NAT10 gene in a juvenile Schnauzer dog with chronic respiratory tract infections

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(3), 1542–1546.

By: B. Hedgespeth n, A. Birkenheuer n , S. Friedenberg*, N. Olby n  & K. Meurs n 

author keywords: ciliary dysplasia; congenital; genetics; microtubule; pneumonia; whole genome sequencing
MeSH headings : Animals; Dog Diseases / genetics; Dogs; Male; Mutation; Mutation, Missense; Respiratory Tract Infections / genetics; Respiratory Tract Infections / veterinary; Whole Genome Sequencing / veterinary
Sources: Web Of Science, ORCID
Added: March 29, 2021

2021 journal article

Dysbiosis of fecal microbiota in cats with naturally occurring and experimentally induced Tritrichomonas foetus infection

PLOS ONE, 16(2).

By: M. Bierlein n, B. Hedgespeth n, M. Azcarate-Peril *, S. Stauffer n & J. Gookin n 

MeSH headings : Animals; Cats; Disease Models, Animal; Dysbiosis / complications; Feces / microbiology; Mice; Microbiota; Protozoan Infections / complications; Protozoan Infections / microbiology; Tritrichomonas foetus / physiology
Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 journal article

Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness

JCI INSIGHT, 6(21).

By: X. Kong*, W. Bennett *, C. Jania*, K. Chason*, Z. German *, J. Adouli*, S. Budney*, B. Oby* ...

MeSH headings : Adenosine Triphosphate / metabolism; Animals; Bronchial Hyperreactivity / metabolism; Female; Humans; Mast Cells / metabolism; Mice; Ozone / adverse effects
Sources: Web Of Science, ORCID
Added: January 31, 2022

2020 journal article

Association of fecal sample collection technique and treatment history with Tritrichomonas foetus polymerase chain reaction test results in 1717 cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 734–741.

By: B. Hedgespeth n, S. Stauffer n, J. Robertson n  & J. Gookin n 

author keywords: diarrhea; retrospective; risk factors; ronidazole
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Feces / parasitology; Female; Male; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Retrospective Studies; Ronidazole / therapeutic use; Specimen Handling / veterinary; Tritrichomonas foetus / isolation & purification; United States
Sources: Web Of Science, ORCID
Added: February 27, 2020