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Works (33)

Updated: March 24th, 2025 05:00

2025 chapter

Chapter 7: Statistics for Engineers

In Teaching and Learning Mathematics Online, 2nd Edition.

Contributors: C. Smith, K. Weems, R. Moore & C. Smith

Source: ORCID
Added: March 12, 2025

2025 journal article

Similarities and Differences Between Inferential Statistics and Global Haiku

CHANCE.

By: C. Smith & D. McMurray

Contributors: C. Smith*

topics (OpenAlex): Grey System Theory Applications
Source: ORCID
Added: March 12, 2025

2024 conference paper

Exploring Sway Metrics of Intermittency in the Feedback Postural Control for Assessing Balance Impairment in Patients with Parkinson’s Disease

2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Orlando, FL, USA, 2024, 1–4,

By: K. Matsui

Contributors: C. Smith

Source: ORCID
Added: March 12, 2025

2024 article proceedings

Exploring Sway Metrics of Intermittency in the Feedback Postural Control for Assessing Balance Impairment in Patients with Parkinson’s Disease

By: K. Matsui, Y. Suzuki, A. Nakamura, C. Smith, K. Nomura, T. Endo, S. Sakoda, P. Morasso, T. Nomura

topics (OpenAlex): Balance, Gait, and Falls Prevention; Cerebral Palsy and Movement Disorders; Effects of Vibration on Health
Sources: Crossref, NC State University Libraries
Added: March 13, 2025

2024 journal article

Smartphone usage during walking decreases the positive persistency in gait cycle variability

Scientific Reports, 14(1).

By: S. Yano*, A. Nakamura*, Y. Suzuki*, C. Smith n & T. Nomura*

Contributors: C. Smith n

topics (OpenAlex): Balance, Gait, and Falls Prevention; Noise Effects and Management; Heart Rate Variability and Autonomic Control
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 28, 2024

2022 journal article

A simple neuronal model with intrinsic saturation of the firing frequency

Biosystems, 222, 104780.

By: R. Tomar*, C. Smith n & P. Lansky*

author keywords: Rate coding; Temporal coding; Neuronal models; Leaky integrate-and-fire; Firing rate; Reversal potential
MeSH headings : Models, Neurological; Neurons / physiology; Membrane Potentials / physiology; Physical Phenomena; Action Potentials / physiology
topics (OpenAlex): Neural dynamics and brain function; stochastic dynamics and bifurcation; Advanced Memory and Neural Computing
TL;DR: The results suggest that the reversal potential increases the slope of the "firing rate vs input" curve due to a smaller effective membrane time constant, but does not necessarily induce saturation of the firing rate. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: November 21, 2022

2017 journal article

Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia

NEUROSCIENCE LETTERS, 661, 11–17.

By: R. Butler n, S. Ehling n, M. Barbar n, J. Thomas n, M. Hughes n, C. Smith n, V. Pogorelov*, D. Aryal* ...

author keywords: Nociception; Contextual fear; Fear-conditioned analgesia; Amygdala; cFos; Neural circuits
MeSH headings : Acute Pain / physiopathology; Amygdala / physiopathology; Analgesia / methods; Animals; Central Amygdaloid Nucleus / metabolism; Conditioning, Psychological / physiology; Fear / physiology; Male; Mice, Inbred C57BL; Neurons / metabolism; Pain Management; Periaqueductal Gray / metabolism; Periaqueductal Gray / physiopathology
topics (OpenAlex): Stress Responses and Cortisol; Pain Mechanisms and Treatments; Receptor Mechanisms and Signaling
TL;DR: The results show that amygdala processing of conditioned contextual aversive, nociceptive, and FCA behaviors involve different neuronal phenotypes and neural circuits between, within, and from various amygdala nuclei. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Pilot evaluation of a novel unilateral onychectomy model and efficacy of an extended release buprenorphine product

BMC Veterinary Research, 13.

By: M. Enomoto, P. Kigin, D. Bledsoe, R. Slone, J. Hash, C. Smith, B. Lascelles

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Universal and individual characteristics of postural sway during quiet standing in healthy young adults

Physiological Reports, 3(3), e12329.

By: T. Yamamoto, C. Smith, Y. Suzuki, K. Kiyono, T. Tanahashi, S. Sakoda, P. Morasso, T. Nomura

Sources: Crossref, NC State University Libraries
Added: March 13, 2025

2012 journal article

8B45 A Statistical Classification of Upright Postural Sway in Healthy Adults and Patients with Parkinson's Disease

The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME, 2012.24(0), _8B45-1_-_8B45-2_.

By: T. Yamamoto*, C. Smith n, Y. Suzuki*, T. Tanahashi*, T. Endo*, S. Sakoda*, T. Nomura*

topics (OpenAlex): Parkinson's Disease and Spinal Disorders; Musculoskeletal pain and rehabilitation
Sources: Crossref, NC State University Libraries
Added: March 22, 2025

2012 journal article

Advanced Oxidation of Toluene Using Ni-Olivine Catalysts: Part 2. Toluene Oxidation Kinetics and Mechanism of Ni-Olivine Catalysts Synthesized via Electroless Deposition and Thermal Impregnation

Transactions of the ASABE, 55(6), 2273–2283.

By: V. Smith n, P. Kolar n, M. Boyette n, M. Chinn n, C. Smith n, R. Gangadharan*, G. Zhang

topics (OpenAlex): Electrocatalysts for Energy Conversion; Electrodeposition and Electroless Coatings; Catalytic Processes in Materials Science
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2012 journal article

Advanced oxidation of toluene using Ni-olivine catalysts: Part 1. syntheses, characterization, and evaluation of Ni-olivine catalysts for toluene oxidation

Transactions of the ASABE, 55(3), 1013–1024.

By: V. Smith, P. Kolar, M. Boyette, M. Chinn, C. Smith, R. Gangadharan, G. Zhang

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Modeling the Effects of Sodium Chloride, Acetic Acid, and Intracellular pH on Survival of Escherichia coli O157:H7

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 77(3), 889–895.

By: A. Hosein n, F. Breidt n & C. Smith n

MeSH headings : Acetic Acid / pharmacology; Animals; Cattle; Colony Count, Microbial; Escherichia coli O157 / drug effects; Escherichia coli O157 / growth & development; Escherichia coli O157 / metabolism; Food Microbiology; Hydrogen-Ion Concentration; Models, Biological; Sodium Chloride / pharmacology; Vegetables / microbiology
topics (OpenAlex): Listeria monocytogenes in Food Safety; Microbial Inactivation Methods; Essential Oils and Antimicrobial Activity
TL;DR: The data revealed a protective effect of NaCl concentration on cell survival for selected acetic acid concentrations, and decreases in intracellular pH were significantly correlated with the corresponding times required to achieve a 5-log reduction in the number of bacteria. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression

AMERICAN JOURNAL OF HUMAN GENETICS, 89(2), 277–288.

MeSH headings : Chromosomes, Human, Pair 21 / genetics; Computer Simulation; Databases, Genetic; Environment; Genes / genetics; Genetic Markers; Humans; Models, Genetic; Mutation / genetics; Quantitative Trait, Heritable; Regression Analysis
topics (OpenAlex): Folate and B Vitamins Research; Genetic Associations and Epidemiology; Genetic and phenotypic traits in livestock
TL;DR: A similarity-based regression method for assessing the main genetic and interaction effects of a group of markers on quantitative traits and is an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium blocks, genes, or pathways in whole-genome analysis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2008 journal article

A continuous time version and a generalization of a Markov-recapture model for trapping experiments

MATHEMATICAL BIOSCIENCES, 214(1-2), 11–19.

By: R. Alpizar-Jara n & C. Smith n

author keywords: capture-recapture experiment; discrete and continuous time Markov process; uniformization; transition probability matrix; multinomial distribution; maximum likelihood estimation; population size estimation
MeSH headings : Algorithms; Animals; Biometry / methods; Computer Simulation; Ecology / methods; Likelihood Functions; Markov Chains; Models, Statistical; Population Density; Time Factors
topics (OpenAlex): Diffusion and Search Dynamics; Survey Sampling and Estimation Techniques; Avian ecology and behavior
TL;DR: A four-state discrete time Markov process is proposed, which describes the structure of a marking-capture experiment as a method of population estimation and provides a mark-recapture estimate from a single trap observation by allowing subjects to mark themselves. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Application of complex demodulation on bZIP and bHLH-PAS protein domains

Mathematical Biosciences, 207(2), 204–218.

By: Z. Wang n, C. Smith n & W. Atchley n

MeSH headings : Algorithms; Amino Acid Motifs; Amino Acid Sequence; Aryl Hydrocarbon Receptor Nuclear Translocator / chemistry; Basic Helix-Loop-Helix Transcription Factors / chemistry; Basic-Leucine Zipper Transcription Factors / chemistry; Computational Biology / methods; Databases, Protein; Entropy; Factor Analysis, Statistical; Fourier Analysis; Humans; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos / chemistry
topics (OpenAlex): Fractal and DNA sequence analysis; Machine Learning in Bioinformatics; Protein Structure and Dynamics
TL;DR: This work analyzed bZIP and bHLH-PAS protein domains and introduced complex demodulation (CDM) to detect functional regions in protein sequences data and found that the local amplitude minimum or local amplitude maximum of the 3.6-aa periodic component is associated with protein structural or functional information. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2004 journal article

Almost sure comparisons for first passage times of diffusion processes through boundaries

METHODOLOGY AND COMPUTING IN APPLIED PROBABILITY, 6(3), 323–341.

By: L. Sacerdote* & C. Smith n

author keywords: diffusion process; first passage time; comparison theorem; Feller process; Ornstein-Uhlenbeck process
topics (OpenAlex): Stochastic processes and financial applications; Stochastic processes and statistical mechanics; Markov Chains and Monte Carlo Methods
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 manuscript

Ama no gawa

(Vol. 56, p. 202).

By: C. Smith

Source: NC State University Libraries
Added: August 6, 2018

2002 chapter

Kezu de tadoru sakabiki haijin maikan

In Kezu de tadoru sakabiki haijin maikan Mainichi shimbun = Poems from the 6th annual Mainichi Haiku Contest (p. 202). Tokyo: Mainichi shimbun.

By: C. Smith

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

A Physiologically Based Pharmacokinetic Model for Methyl tert-Butyl Ether in Humans: Implementing Sensitivity and Variability Analyses

Toxicological Sciences, 62(2), 191–204.

By: A. Licata*, W. Dekant, C. Smith & S. Borghoff

author keywords: physiologically based pharmacokinetic (PBPK); model; methyl tert-butyl ether (MTBE); sensitivity analysis; variability analysis
MeSH headings : Administration, Inhalation; Dose-Response Relationship, Drug; Female; Humans; Male; Methyl Ethers / administration & dosage; Methyl Ethers / pharmacokinetics; Models, Biological; Sensitivity and Specificity
topics (OpenAlex): Carcinogens and Genotoxicity Assessment; Toxic Organic Pollutants Impact; Air Quality and Health Impacts
TL;DR: By incorporating an understanding of the metabolic processes, this PBPK model can be used to predict blood levels of MTBE, which is important in determining target tissue dose estimates for risk assessment. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2001 journal article

Mixture Effects of JP-8 Additives on the Dermal Disposition of Jet Fuel Components

Toxicology and Applied Pharmacology, 175(3), 269–281.

By: R. Baynes n, J. Brooks n, K. Budsaba n, C. Smith n & J. Riviere n

author keywords: jet fuels; mixtures; skin; interactions; absorption
MeSH headings : Alkanes / pharmacokinetics; Animals; Drug Synergism; Hydrocarbons / chemistry; Hydrocarbons / pharmacokinetics; In Vitro Techniques; Kerosene; Naphthalenes / pharmacokinetics; Perfusion; Skin / drug effects; Skin / metabolism; Skin Absorption; Swine; Tissue Distribution
topics (OpenAlex): Advancements in Transdermal Drug Delivery; Contact Dermatitis and Allergies; Bee Products Chemical Analysis
TL;DR: The data suggest that various combinations of these three performance additives in JP-8 can potentially alter the dermal disposition of aromatic and aliphatic fuel components in skin. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2001 journal article

Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard

JOURNAL OF APPLIED TOXICOLOGY, 21(2), 91–99.

By: J. Riviere n, C. Smith n, K. Budsaba n, J. Brooks n, E. Olajos*, H. Salem*, N. Monteiro-Riviere n

Contributors: J. Riviere n, C. Smith n, K. Budsaba n, J. Brooks n, E. Olajos*, H. Salem*, N. Monteiro-Riviere n

MeSH headings : Administration, Cutaneous; Adsorption; Animals; Area Under Curve; Carbon Radioisotopes; Culture Techniques; Dermatologic Agents / pharmacokinetics; Fixatives; Models, Biological; Mustard Gas / pharmacokinetics; Salicylates / pharmacokinetics; Skin / drug effects; Skin / pathology; Swine
topics (OpenAlex): Pesticide Exposure and Toxicity; Contact Dermatitis and Allergies; Animal testing and alternatives
TL;DR: Compared with other chemicals studied in this model, HD and MS cutaneous disposition were very similar, supporting the use of MS as a dermal simulant for HD exposure. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2000 journal article

A qualitative comparison of some diffusion models for neural activity via stochastic ordering

BIOLOGICAL CYBERNETICS, 83(6), 543–551.

By: L. Sacerdote* & C. Smith n

MeSH headings : Action Potentials / physiology; Algorithms; Animals; Diffusion; Membrane Potentials / physiology; Models, Neurological; Neurons / physiology; Stochastic Processes
topics (OpenAlex): stochastic dynamics and bifurcation; Neural Networks and Applications; Neural dynamics and brain function
TL;DR: This work compares the distribution of interspike intervals from different models using the method of stochastic ordering and concludes that the Feller model gives shorter times than the Ornstein-Uhlenbeck model but longer times than the authors' double reversal potential model. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Compass plots: A combination of star plot and analysis of means to visualize significant interactions in complex toxicology studies

TOXICOLOGY METHODS, 10(4), 313–332.

By: K. Budsaba n, C. Smith n & J. Riviere n

author keywords: analysis of means; Bonferroni method; chemical mixtures; 2(p) factorial experiments; Kimball inequality; parathion; star plot; Yates algorithm
topics (OpenAlex): Sensory Analysis and Statistical Methods; Advanced Statistical Methods and Models; Optimal Experimental Design Methods
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Conditions for noise reduction and stable encoding of spatial structure by cortical neural networks

BIOLOGICAL CYBERNETICS, 82(6), 469–475.

By: B. Gutkin* & C. Smith n

MeSH headings : Animals; Haplorhini; Models, Biological; Nerve Net; Somatosensory Cortex / physiology
topics (OpenAlex): Neural dynamics and brain function; Advanced Memory and Neural Computing; Neural Networks and Applications
TL;DR: It is proved that a network with a connection matrix, where the total excitation and inhibition impinging upon a neural unit are nearly balanced, will yield stable spatial attractor responses. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 article

New parameter relationships determined via stochastic ordering for spike activity in a reversal potential neural model

BIOSYSTEMS, Vol. 58, pp. 59–65.

By: L. Sacerdote* & C. Smith n

author keywords: Feller model; stochastic order; interspike interval distribution
MeSH headings : Action Potentials; Models, Neurological
topics (OpenAlex): stochastic dynamics and bifurcation; Neural dynamics and brain function; Lipid Membrane Structure and Behavior
TL;DR: The functional dependence among the model parameters (e.g, membrane time constant, reversal potential, etc.) resulting from the ordering criteria employed and from the study of mean trajectory plots is analyzed into detail for four different scenario. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

Cycle time and residence time density approximations in a stochastic model for circulatory transport

Bulletin of Mathematical Biology, 59(1), 1–22.

By: C. Smith n, P. Lansky* & T. Lung n

MeSH headings : Humans; Mathematics; Metabolic Clearance Rate; Models, Biological; Pharmacokinetics; Stochastic Processes
topics (OpenAlex): Diffusion Coefficients in Liquids; Thermodynamic properties of mixtures; Statistical Distribution Estimation and Applications
TL;DR: The concentration of a drug in the circulatory system is studied under two different elimination strategies and laguerre series expansions, which yield a parsimonious approximation of positively skewed probability densities that are close to a gamma distribution. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

1995 chapter book

On the Stochastic Stability of a Neural Network Model of Somatosensory Information Processing

By: B. Gutkin* & C. Smith n

topics (OpenAlex): Neural Networks and Applications; Neural Networks Stability and Synchronization; Neural dynamics and brain function
Sources: Crossref, NC State University Libraries
Added: March 16, 2025

1994 journal article

A reliability application of a mixture of inverse gaussian distributions

Applied Stochastic Models and Data Analysis, 10(1), 61–69.

By: C. Smith n & P. Lánský*

topics (OpenAlex): Probabilistic and Robust Engineering Design; Statistical Distribution Estimation and Applications; Scientific Measurement and Uncertainty Evaluation
Sources: Crossref, NC State University Libraries
Added: March 22, 2025

1994 journal article

Synaptic Transmission in a Diffusion Model for Neural Activity

Journal of Theoretical Biology, 166(4), 393–406.

By: V. Lánská n, P. Lánský n & C. Smith n

topics (OpenAlex): Neural dynamics and brain function; stochastic dynamics and bifurcation; Neuroscience and Neural Engineering
Sources: Crossref, NC State University Libraries
Added: March 22, 2025

1992 chapter book

A Heuristic Approach to Stochastic Models of Single Neurons

By: C. Smith n

topics (OpenAlex): stochastic dynamics and bifurcation; Spectroscopy and Quantum Chemical Studies; Diffusion and Search Dynamics
Sources: Crossref, NC State University Libraries
Added: March 16, 2025

1992 journal article

A note on neuronal firing and input variability

Journal of Theoretical Biology, 154(3), 271–275.

By: C. Smith n

topics (OpenAlex): Neural dynamics and brain function; stochastic dynamics and bifurcation; Diffusion and Search Dynamics
Sources: Crossref, NC State University Libraries
Added: March 16, 2025

1992 journal article

Effects of afterhyperpolarization on neuronal firing

Biosystems, 27(1), 25–38.

By: P. Lánský*, M. Musila* & C. Smith n

topics (OpenAlex): Force Microscopy Techniques and Applications; stochastic dynamics and bifurcation; Neural dynamics and brain function
Sources: Crossref, NC State University Libraries
Added: March 22, 2025

Employment

Updated: September 30th, 2016 01:23

1983 - present

North Carolina State University Raleigh, NC, US
Assoc Prof Statistics

Education

Updated: March 12th, 2025 07:46

1976 - 1979

The University of Chicago Chicago, IL, US
Ph.D. Biophysics and Theoretical Biology

1972 - 1973

The University of Chicago Chicago, IL, US
M.S. Theoretical Biology

1968 - 1972

Massachusetts Institute of Technology Cambridge, Massachusetts, US
B.S. Physics

Funding History

Funding history based on the linked ORCID record. Updated: March 12th, 2025 07:18

award September 1, 2023 - February 1, 2024
Statistical and Stochastic Modeling of Postural Sway during Quiet Standing in Health and Disease
Fulbright Scholars

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