Charles Eugene Smith

Works (17)

Updated: August 16th, 2024 13:37

2022 journal article

A simple neuronal model with intrinsic saturation of the firing frequency

BIOSYSTEMS, 222.

By: R. Tomar*, C. Smith n & P. Lansky*

author keywords: Rate coding; Temporal coding; Neuronal models; Leaky integrate-and-fire; Firing rate; Reversal potential
MeSH headings : Models, Neurological; Neurons / physiology; Membrane Potentials / physiology; Physical Phenomena; Action Potentials / physiology
TL;DR: The results suggest that the reversal potential increases the slope of the "firing rate vs input" curve due to a smaller effective membrane time constant, but does not necessarily induce saturation of the firing rate. (via Semantic Scholar)
Source: Web Of Science
Added: November 21, 2022

2017 journal article

Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia

NEUROSCIENCE LETTERS, 661, 11–17.

By: R. Butler n, S. Ehling n, M. Barbar n, J. Thomas n, M. Hughes n, C. Smith n, V. Pogorelov*, D. Aryal* ...

author keywords: Nociception; Contextual fear; Fear-conditioned analgesia; Amygdala; cFos; Neural circuits
MeSH headings : Acute Pain / physiopathology; Amygdala / physiopathology; Analgesia / methods; Animals; Central Amygdaloid Nucleus / metabolism; Conditioning, Psychological / physiology; Fear / physiology; Male; Mice, Inbred C57BL; Neurons / metabolism; Pain Management; Periaqueductal Gray / metabolism; Periaqueductal Gray / physiopathology
TL;DR: The results show that amygdala processing of conditioned contextual aversive, nociceptive, and FCA behaviors involve different neuronal phenotypes and neural circuits between, within, and from various amygdala nuclei. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Pilot evaluation of a novel unilateral onychectomy model and efficacy of an extended release buprenorphine product

BMC Veterinary Research, 13.

By: M. Enomoto, P. Kigin, D. Bledsoe, R. Slone, J. Hash, C. Smith, B. Lascelles

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Advanced oxidation of toluene using Ni-olivine catalysts: Part 1. syntheses, characterization, and evaluation of Ni-olivine catalysts for toluene oxidation

Transactions of the ASABE, 55(3), 1013–1024.

By: V. Smith, P. Kolar, M. Boyette, M. Chinn, C. Smith, R. Gangadharan, G. Zhang

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression

AMERICAN JOURNAL OF HUMAN GENETICS, 89(2), 277–288.

MeSH headings : Chromosomes, Human, Pair 21 / genetics; Computer Simulation; Databases, Genetic; Environment; Genes / genetics; Genetic Markers; Humans; Models, Genetic; Mutation / genetics; Quantitative Trait, Heritable; Regression Analysis
TL;DR: A similarity-based regression method for assessing the main genetic and interaction effects of a group of markers on quantitative traits and is an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium blocks, genes, or pathways in whole-genome analysis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Modeling the Effects of Sodium Chloride, Acetic Acid, and Intracellular pH on Survival of Escherichia coli O157:H7

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 77(3), 889–895.

By: A. Hosein n, F. Breidt n & C. Smith n

MeSH headings : Acetic Acid / pharmacology; Animals; Cattle; Colony Count, Microbial; Escherichia coli O157 / drug effects; Escherichia coli O157 / growth & development; Escherichia coli O157 / metabolism; Food Microbiology; Hydrogen-Ion Concentration; Models, Biological; Sodium Chloride / pharmacology; Vegetables / microbiology
TL;DR: The data revealed a protective effect of NaCl concentration on cell survival for selected acetic acid concentrations, and decreases in intracellular pH were significantly correlated with the corresponding times required to achieve a 5-log reduction in the number of bacteria. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

A continuous time version and a generalization of a Markov-recapture model for trapping experiments

MATHEMATICAL BIOSCIENCES, 214(1-2), 11–19.

By: R. Alpizar-Jara & C. Smith n

author keywords: capture-recapture experiment; discrete and continuous time Markov process; uniformization; transition probability matrix; multinomial distribution; maximum likelihood estimation; population size estimation
MeSH headings : Algorithms; Animals; Biometry / methods; Computer Simulation; Ecology / methods; Likelihood Functions; Markov Chains; Models, Statistical; Population Density; Time Factors
TL;DR: A four-state discrete time Markov process is proposed, which describes the structure of a marking-capture experiment as a method of population estimation and provides a mark-recapture estimate from a single trap observation by allowing subjects to mark themselves. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Application of complex demodulation on bZIP and bHLH-PAS protein domains

Mathematical Biosciences, 207(2), 204–218.

By: Z. Wang n, C. Smith n & W. Atchley n

MeSH headings : Algorithms; Amino Acid Motifs; Amino Acid Sequence; Aryl Hydrocarbon Receptor Nuclear Translocator / chemistry; Basic Helix-Loop-Helix Transcription Factors / chemistry; Basic-Leucine Zipper Transcription Factors / chemistry; Computational Biology / methods; Databases, Protein; Entropy; Factor Analysis, Statistical; Fourier Analysis; Humans; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos / chemistry
TL;DR: This work analyzed bZIP and bHLH-PAS protein domains and introduced complex demodulation (CDM) to detect functional regions in protein sequences data and found that the local amplitude minimum or local amplitude maximum of the 3.6-aa periodic component is associated with protein structural or functional information. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Almost sure comparisons for first passage times of diffusion processes through boundaries

METHODOLOGY AND COMPUTING IN APPLIED PROBABILITY, 6(3), 323–341.

By: L. Sacerdote* & C. Smith n

author keywords: diffusion process; first passage time; comparison theorem; Feller process; Ornstein-Uhlenbeck process
Source: Web Of Science
Added: August 6, 2018

2002 manuscript

Ama no gawa

(Vol. 56, p. 202).

By: C. Smith

Source: NC State University Libraries
Added: August 6, 2018

2002 chapter

Kezu de tadoru sakabiki haijin maikan

In Kezu de tadoru sakabiki haijin maikan Mainichi shimbun = Poems from the 6th annual Mainichi Haiku Contest (p. 202). Tokyo: Mainichi shimbun.

By: C. Smith

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard

JOURNAL OF APPLIED TOXICOLOGY, 21(2), 91–99.

By: J. Riviere n, C. Smith n, K. Budsaba n, J. Brooks n, E. Olajos*, H. Salem*, N. Monteiro-Riviere n

Contributors: J. Riviere n, C. Smith n, K. Budsaba n, J. Brooks n, E. Olajos*, H. Salem*, N. Monteiro-Riviere n

MeSH headings : Administration, Cutaneous; Adsorption; Animals; Area Under Curve; Carbon Radioisotopes; Culture Techniques; Dermatologic Agents / pharmacokinetics; Fixatives; Models, Biological; Mustard Gas / pharmacokinetics; Salicylates / pharmacokinetics; Skin / drug effects; Skin / pathology; Swine
TL;DR: Compared with other chemicals studied in this model, HD and MS cutaneous disposition were very similar, supporting the use of MS as a dermal simulant for HD exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2000 journal article

A qualitative comparison of some diffusion models for neural activity via stochastic ordering

BIOLOGICAL CYBERNETICS, 83(6), 543–551.

By: L. Sacerdote* & C. Smith n

MeSH headings : Action Potentials / physiology; Algorithms; Animals; Diffusion; Membrane Potentials / physiology; Models, Neurological; Neurons / physiology; Stochastic Processes
TL;DR: This work compares the distribution of interspike intervals from different models using the method of stochastic ordering and concludes that the Feller model gives shorter times than the Ornstein-Uhlenbeck model but longer times than the authors' double reversal potential model. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Compass plots: A combination of star plot and analysis of means to visualize significant interactions in complex toxicology studies

TOXICOLOGY METHODS, 10(4), 313–332.

By: K. Budsaba n, C. Smith n & J. Riviere n

author keywords: analysis of means; Bonferroni method; chemical mixtures; 2(p) factorial experiments; Kimball inequality; parathion; star plot; Yates algorithm
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Conditions for noise reduction and stable encoding of spatial structure by cortical neural networks

BIOLOGICAL CYBERNETICS, 82(6), 469–475.

By: B. Gutkin* & C. Smith n

MeSH headings : Animals; Haplorhini; Models, Biological; Nerve Net; Somatosensory Cortex / physiology
TL;DR: It is proved that a network with a connection matrix, where the total excitation and inhibition impinging upon a neural unit are nearly balanced, will yield stable spatial attractor responses. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 article

New parameter relationships determined via stochastic ordering for spike activity in a reversal potential neural model

BIOSYSTEMS, Vol. 58, pp. 59–65.

By: L. Sacerdote* & C. Smith n

author keywords: Feller model; stochastic order; interspike interval distribution
MeSH headings : Action Potentials; Models, Neurological
TL;DR: The functional dependence among the model parameters (e.g, membrane time constant, reversal potential, etc.) resulting from the ordering criteria employed and from the study of mean trajectory plots is analyzed into detail for four different scenario. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Cycle time and residence time density approximations in a stochastic model for circulatory transport

Bulletin of Mathematical Biology, 59(1), 1–22.

By: C. Smith n, P. Lansky* & T. Lung n

MeSH headings : Humans; Mathematics; Metabolic Clearance Rate; Models, Biological; Pharmacokinetics; Stochastic Processes
TL;DR: The concentration of a drug in the circulatory system is studied under two different elimination strategies and laguerre series expansions, which yield a parsimonious approximation of positively skewed probability densities that are close to a gamma distribution. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

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