Bruce W Keene

Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure*

JOURNAL OF VETERINARY CARDIOLOGY, 40, 99–109.

A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat

ORPHANET JOURNAL OF RARE DISEASES, 16(1).

Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy

ANIMAL GENETICS, 52(4), 542–544.

Letter to the editor regarding "Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial"

Atkins, C., Keene, B., DeFrancesco, T. C., Tou, S., Chetboul, V., Cote, E., … Stepien, R. L. (2021, March).

Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 259(12), 1428–1432.

Use of whole genome analysis to identify shared genomic variants across breeds in canine mitral valve disease

Williams, B., Friedenberg, S. G., Keene, B. W., Tou, S. P., DeFrancesco, T. C., & Meurs, K. M. (2021, June 27). HUMAN GENETICS, Vol. 6.

What Is Your Diagnosis?

Tucker, S., Archibald, K., Cohen, E. B., Sommer, S., Keene, B. W., Minter, L. J., & Delk, K. W. (2021, December). JOURNAL OF AVIAN MEDICINE AND SURGERY, Vol. 35, pp. 486–493.

Atenolol in cats with subclinical hypertrophic cardiomyopathy: a double-blind, placebo-controlled, randomized clinical trial of effect on quality of life, activity, and cardiac biomarkers

JOURNAL OF VETERINARY CARDIOLOGY, 30, 77–91.

Clinical presentation, cardiovascular findings, etiology, and outcome of myocarditis in dogs: 64 cases with presumptive antemortem diagnosis (26 confirmed postmortem) and 137 cases with postmortem diagnosis only (2004-2017)

JOURNAL OF VETERINARY CARDIOLOGY, 30, 44–56.

Renin-angiotensin aldosterone profile before and after angiotensin-converting enzyme-inhibitor administration in dogs with angiotensin-converting enzyme gene polymorphism

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 600–606.

Retrospective evaluation of the safety and tolerability of pimobendan in cats with obstructive vs nonobstructive cardiomyopathy

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(6), 2211–2222.

Species differences in cardiovascular physiology that affect pharmacology and toxicology

CURRENT OPINION IN TOXICOLOGY, 23-24, 106–113.

Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(3), 1108–1118.

A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death

Human Genetics, 138(5), 515–524.

ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(3), 1127–1140.

Clinical ethics consultation in a tertiary care veterinary teaching hospital

Adin, C. A., Moga, J. L., Keene, B. W., Fogle, C. A., Hopkinson, H. R., Weyhrauch, C. A., … Rosoff, P. M. (2019, January 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 254, pp. 52–60.

Dilated cardiomyopathy in 151 Irish Wolfhounds: Characteristic clinical findings, life expectancy and causes of death

VETERINARY JOURNAL, 245, 15–21.

Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type

JOURNAL OF VETERINARY CARDIOLOGY, 21, 1–9.

Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy

VETERINARY JOURNAL, 243, 21–25.

Irish wolfhounds with subclinical atrial fibrillation: progression of disease and causes of death

JOURNAL OF VETERINARY CARDIOLOGY, 24, 48–57.

Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(6), 2572–2586.

Myxomatous mitral valve disease in the miniature poodle: A retrospective study

VETERINARY JOURNAL, 244, 94–97.

The effect of a surgical safety checklist on complication rates associated with permanent transvenous pacemaker implantation in dogs

JOURNAL OF VETERINARY CARDIOLOGY, 22, 72–83.

Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration

VETERINARY JOURNAL, 232, 16–19.

International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study

Journal of Veterinary Internal Medicine, 32(3), 930–943.

Longitudinal analysis of quality of life, clinical, radiographic, echocardiographic, and laboratory variables in dogs with preclinical myxomatous mitral valve disease receiving pimobendan or placebo: The EPIC study

Journal of Veterinary Internal Medicine, 32(1), 72–85.

Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model

AMERICAN JOURNAL OF BIOETHICS, 18(2), 41–53.

Response to Open Peer Commentaries on "Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model"

Accuracy of point-of-care lung ultrasonography for the diagnosis of cardiogenic pulmonary edema in dogs and cats with acute dyspnea

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 250(6), 666–675.

Angiotensin-converting enzyme activity and inhibition in dogs with cardiac disease and an angiotensin-converting enzyme polymorphism

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 18(4).

Effect of pimobendan in Dogs with preclinical myxomatous mitral valve disease and cardiomegaly: The EPIC study - A randomized clinical trial

Kleintier-Praxis, 62(2), 64–87.

Pilot study to determine the feasibility of radiation therapy for dogs with right atrial masses and hemorrhagic pericardial effusion

Journal of Veterinary Cardiology, 19(2), 132–143.

The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(4), 206–213.

Development of a Veterinary Surgical Checklist

ERGONOMICS IN DESIGN, 24(4), 27–34.

Effect of Pimobendan in dogs with preclinical myxomatous mitral valve disease and cardiomegaly: The EPIC study-a randomized clinical trial

Journal of Veterinary Internal Medicine, 30(6), 1765–1779.

Infective endocarditis in 13 cats

Journal of Veterinary Cardiology, 18(3), 213–225.

Outcome and survival in canine sick sinus syndrome and sinus node dysfunction: 93 cases (2002-2014)

JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 199–212.

Successful treatment of mitral valve endocarditis in a dog associated with 'Actinomyces canis-like' infection

JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 271–277.

Suspected acute myocardial infarction in a dystrophin-deficient dog

NEUROMUSCULAR DISORDERS, 26(6), 361–366.

Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy

AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(7), 693–699.

A VALENTINE-SHAPED CARDIAC SILHOUETTE IN FELINE THORACIC RADIOGRAPHS IS PRIMARILY DUE TO LEFT ATRIAL ENLARGEMENT

VETERINARY RADIOLOGY & ULTRASOUND, 56(3), 245–250.

Aldosterone breakthrough with benazepril in furosemide-activated renin-angiotensin-aldosterone system in normal dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 38(1), 65–73.

Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts

Journal of Cellular and Molecular Medicine, 19(8), 1805–1813.

Complication Rates Associated with Transvenous Pacemaker Implantation in Dogs with High-Grade Atrioventricular Block Performed During versus After Normal Business Hours

JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(1), 157–163.

Cor triatriatum

Veterinary Image-Guided Interventions, 604–609.

Impact of the canine double-deletion beta 1 adrenoreceptor polymorphisms on protein structure and heart rate response to atenolol, a beta 1-selective beta-blocker

PHARMACOGENETICS AND GENOMICS, 25(9), 427–431.

Secondary prevention of cardiogenic arterial thromboembolism in the cat: the double-blind, randomized, positive-controlled feline arterial thromboembolism; clopidogrel vs. aspirin trial (FAT CAT)

JOURNAL OF VETERINARY CARDIOLOGY, 17, S306–S317.

Case-control study of the effects of pimobendan on survival time in cats with hypertrophic cardiomyopathy and congestive heart failure

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 245(5), 534–539.

Outcome of positive-pressure ventilation in dogs and cats with congestive heart failure: 16 cases (1992-2012)

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 24(5), 586–593.

Association of Dilated Cardiomyopathy with the Striatin Mutation Genotype in Boxer Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1437–1440.

Cardiac structure and function in female carrier's of a canine model of Duchenne muscular dystrophy

RESEARCH IN VETERINARY SCIENCE, 94(3), 610–617.

Hybrid cutting balloon dilatation for treatment of cor triatriatum sinister in a cat

JOURNAL OF VETERINARY CARDIOLOGY, 15(3), 205–210.

Outcomes and Complications Associated With Epicardial Pacemakers in 28 Dogs and 5 Cats

VETERINARY SURGERY, 42(5), 544–550.

A splice site mutation in a gene encoding for PDK4, a mitochondrial protein, is associated with the development of dilated cardiomyopathy in the Doberman pinscher

HUMAN GENETICS, 131(8), 1319–1325.

Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies

Mammalian Genome, 23(1-2), 85–108.

Complete atrioventricular block secondary to cardiac lymphoma in a dog

Journal of Veterinary Cardiology, 14(4), 537–539.

Cutting balloon catheterization for interventional treatment of cor triatriatum dexter: 2 Cases

Journal of Veterinary Cardiology, 14(4), 525–530.

Surgical treatment of a pulmonary artery vascular hamartoma in a dog

Journal of the American Veterinary Medical Association, 240(7), 858–862.

ECG of the Month

Tou, S. P., DeFrancesco, T. C., & Keene, B. W. (2011, July 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 239, pp. 55–57.

Multicenter Evaluation of Plasma N-Terminal Probrain Natriuretic Peptide (NT-pro BNP) as a Biochemical Screening Test for Asymptomatic (occult) Cardiomyopathy in Cats

Journal of Veterinary Internal Medicine, 25(5), 1010–1016.

Pulmonary atresia and ventricular septal defect with aortopulmonary collaterals in an adult dog

Journal of Veterinary Cardiology, 13(4), 271–275.

Successful treatment ofBartonella henselaeendocarditis in a cat

Journal of Feline Medicine and Surgery, 12(6), 483–486.

Acute Effect of Pimobendan and Furosemide on the Circulating Renin-Angiotensin-Aldosterone System in Healthy Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(5), 1003–1006.

Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease

[Review of ]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(6), 1142–1150.

Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats

Journal of Veterinary Cardiology, 11(Supplement 1), S51–S61.

Comparison of the pharmacokinetic properties of bisoprolol and carvedilol in healthy dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 69(12), 1659–1663.

Electrocardiographic, hematologic, histopathologic, and recovery characteristics from repeated morphine-chloralose anesthesia in dogs

International Journal of Applied Research in Veterinary Medicine, 6(3), 191–199.

Supraventricular tachycardia in dogs: 65 cases (1990-2007)

Finster, S. T., DeFrancesco, T. C., Atkins, C. E., Hansen, B. D., & Keene, B. W. (2008, October). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 18, pp. 503–510.

Use of a nitinol gooseneck snare catheter for removal of adult Dirofilaria immitis in two cats

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 233(9), 1441–1445.

Cystoscopic-guided balloon dilation of a urethral stricture in a female dog

Canadian Veterinary Journal, 48(7), 731–733.

ECG of the month

Adams, A. K., & Keene, B. W. (2007, July 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 231, pp. 209–211.

Estimation of 24-h aldosterone secretion in the dog using the urine aldosterone: Creatinine ratio

Journal of Veterinary Cardiology, 9(1), 1–7.

Evaluation of an accelerometer for at-home monitoring of spontaneous activity in dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 68(5), 468–475.

Lack of GNB3 exon 9 polymorphism in primary hypertensive and normotensive dogs

VETERINARY RECORD, 160(19), 654–657.

Prospective clinical evaluation of an ELISA B-type natriuretic peptide assay in the diagnosis of congestive heart failure in dogs presenting with cough or dyspnea

JOURNAL OF VETERINARY INTERNAL MEDICINE, 21(2), 243–250.

Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency

Journal of the American Veterinary Medical Association, 231(7), 1061–1069.

The effect of amlodipine and the combination of amlodipine and enalapril on the renin-angiotensin-aldosterone system in the dog

Journal of Veterinary Pharmacology and Therapeutics, 30(5), 394–400.

Assessment of drug-induced QT interval prolongation in conscious rabbits

Journal of Pharmacological and Toxicological Methods, 53(2), 168–173.

Bartonella quintana Endocarditis in Dogs

Emerging Infectious Diseases, 12(12), 1869–1872.

Coil occlusion of residual shunts after surgical closure of patent ductus arteriosus

VETERINARY SURGERY, 35(8), 781–785.

Use of a failing rabbit heart as a model to predict torsadogenicity

TOXICOLOGICAL SCIENCES, 93(1), 205–212.

Acute cardiovascular effects of tacrolimus in the isolated guinea pig heart

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(3), 313–316.

Pathology of end-stage remodeling in a family of cats with hypertrophic cardiomyopathy

VETERINARY PATHOLOGY, 42(4), 458–467.

How many cardiac cycles must be measured to permit accurate RR, QT, and QTc estimates in conscious dogs?

Journal of Pharmacological and Toxicological Methods, 50(2), 103–108.

Recovery of pelvic limb function in dogs following acute intervertebral disc herniations

JOURNAL OF NEUROTRAUMA, 21(1), 49–59.

Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc

Journal of Pharmacological and Toxicological Methods, 49(1), 15–23.

Accuracy of heart rate obtained by auscultation in atrial fibrillation

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(3), 237–239.

Noninvasive transthoracic temporary cardiac pacing in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 17, pp. 663–667.

QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles

TOXICOLOGICAL SCIENCES, 76(2), 437–442.

Spontaneous resolution of an isolated ventricular septal defect in a dog

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 223(2), 219–220.

Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers

Journal of the American Veterinary Medical Association, 221(4), 522–527.

Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation

Journal of the American Veterinary Medical Association, 221(5), 654–658.

Hypercalcemia and high parathyroid hormone-related protein concentration associated with malignant melanoma in a dog

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 221(2), 263-+.

Percutaneous Balloon Pericardiotomy as a Treatment for Recurrent Pericardial Effusion in 6 Dogs

Journal of Veterinary Internal Medicine, 16(5), 541–546.

Percutaneous retrieval of a jugular catheter fragment from the pulmonary artery of a foal

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 220(2), 212–214.

Prospective clinical evaluation of serum cardiac troponin T in dogs admitted to a veterinary teaching hospital

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 553–557.

Development of a functional scoring system in dogs with acute spinal cord injuries

AMERICAN JOURNAL OF VETERINARY RESEARCH, 62(10), 1624–1628.

Metabolic and structural abnormalities in dogs with early left ventricular dysfunction induced by incessant tachycardia

AMERICAN JOURNAL OF VETERINARY RESEARCH, 62(6), 889–894.

Natural history of hypertrophic cardiomyopathy and aortic thromboembolism in a family of domestic shorthair cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, 15(6), 595–599.

Use of echocardiography for the diagnosis of heartworm disease in cats: 43 cases (1985-1997)

Journal of the American Veterinary Medical Association, 218(1), 66–69.

Heartworm infection in cats: 50 cases (1985-1997)

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 217(3), 355–358.

Towards evidence-based veterinary medicine

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 118–119.

A polymerase chain reaction screening strategy for the promoter of the canine dystrophin gene

American Journal of Veterinary Research, 60(9), 1040–1046.

ECG changes after rabbit coronavirus infection

JOURNAL OF ELECTROCARDIOLOGY, 32(1), 21–32.

Prevalence of heartworm infection in cats with signs of cardiorespiratory abnormalities

Journal of the American Veterinary Medical Association, 212(4), 517–520.

Asystole associated with iohexol myelography in a dog

VETERINARY RADIOLOGY & ULTRASOUND, 38(4), 284–287.

Results of the Multicenter Spaniel Trial (MUST): Taurine- and carnitine-responsive dilated cardiomyopathy in American cocker spaniels with decreased plasma taurine concentration

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11, pp. 204–211.

Management of canine dilated cardiomyopathy

Canine Practice (Santa Barbara, Calif. : 1990), 21(1), 27.

ECG of the month

Journal of the American Veterinary Medical Association, 198(3), 408.