Bruce Keene

Walker, A. L., DeFrancesco, T. C., Bonagura, J. D., Keene, B. W., Meurs, K. M., Tou, S. P., … Adin, D. B. (2022). Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure*. JOURNAL OF VETERINARY CARDIOLOGY, 40, 99–109. https://doi.org/10.1016/j.jvc.2021.02.001

Meurs, K. M., Williams, B. G., DeProspero, D., Friedenberg, S. G., Malarkey, D. E., Ezzell, J. A., … Tou, S. (2021). A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat. ORPHANET JOURNAL OF RARE DISEASES, 16(1). https://doi.org/10.1186/s13023-021-01740-5

K. O'Donnell, Adin, D., Atkins, C. E., DeFrancesco, T., Keene, B. W., Tou, S., & Meurs, K. M. (2021). Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy. ANIMAL GENETICS, 52(4), 542–544. https://doi.org/10.1111/age.13074

Atkins, C., Keene, B., DeFrancesco, T. C., Tou, S., Chetboul, V., Cote, E., … Stepien, R. L. (2021, March). Letter to the editor regarding "Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial". https://doi.org/10.1111/jvim.16035

DeProspero, D. J., Kerry A. O'Donnell, DeFrancesco, T. C., Keene, B. W., Tou, S. P., Adin, D. B., … Meurs, K. M. (2021). Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 259(12), 1428–1432. https://doi.org/10.2460/javma.20.05.0291

Williams, B., Friedenberg, S. G., Keene, B. W., Tou, S. P., DeFrancesco, T. C., & Meurs, K. M. (2021, June 27). Use of whole genome analysis to identify shared genomic variants across breeds in canine mitral valve disease. HUMAN GENETICS, Vol. 6. https://doi.org/10.1007/s00439-021-02297-w

Tucker, S., Archibald, K., Cohen, E. B., Sommer, S., Keene, B. W., Minter, L. J., & Delk, K. W. (2021, December). What Is Your Diagnosis? JOURNAL OF AVIAN MEDICINE AND SURGERY, Vol. 35, pp. 486–493. https://doi.org/10.1647/21-00060

Coleman, A. E., DeFrancesco, T. C., Griffiths, E. H., Lascelles, B. D. X., Kleisch, D. J., Atkins, C. E., & Keene, B. W. (2020). Atenolol in cats with subclinical hypertrophic cardiomyopathy: a double-blind, placebo-controlled, randomized clinical trial of effect on quality of life, activity, and cardiac biomarkers. JOURNAL OF VETERINARY CARDIOLOGY, 30, 77–91. https://doi.org/10.1016/j.jvc.2020.06.002

Lakhdhir, S., Viall, A., Alloway, E., Keene, B., Baumgartner, K., & Ward, J. (2020). Clinical presentation, cardiovascular findings, etiology, and outcome of myocarditis in dogs: 64 cases with presumptive antemortem diagnosis (26 confirmed postmortem) and 137 cases with postmortem diagnosis only (2004-2017). JOURNAL OF VETERINARY CARDIOLOGY, 30, 44–56. https://doi.org/10.1016/j.jvc.2020.05.003

Adin, D., Atkins, C., Domenig, O., DeFrancesco, T., Keene, B., Tou, S., … Meurs, K. M. (2020). Renin-angiotensin aldosterone profile before and after angiotensin-converting enzyme-inhibitor administration in dogs with angiotensin-converting enzyme gene polymorphism. JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 600–606. https://doi.org/10.1111/jvim.15746

Ward, J. L., Kussin, E. Z., Tropf, M. A., Tou, S. P., DeFrancesco, T. C., & Keene, B. W. (2020). Retrospective evaluation of the safety and tolerability of pimobendan in cats with obstructive vs nonobstructive cardiomyopathy. JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(6), 2211–2222. https://doi.org/10.1111/jvim.15920

Hamlin, R. L., & Keene, B. W. (2020). Species differences in cardiovascular physiology that affect pharmacology and toxicology. CURRENT OPINION IN TOXICOLOGY, 23-24, 106–113. https://doi.org/10.1016/j.cotox.2020.07.004

Boswood, A., Gordon, S. G., Haggstrom, J., Vanselow, M., Wess, G., Stepien, R. L., … Watson, P. (2020). Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study. JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(3), 1108–1118. https://doi.org/10.1111/jvim.15753

Meurs, K. M., Friedenberg, S. G., Kolb, J., Saripalli, C., Tonino, P., Woodruff, K., … Granzier, H. (2019). A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death. Human Genetics, 138(5), 515–524. https://doi.org/10.1007/s00439-019-01973-2

Keene, B. W., Atkins, C. E., Bonagura, J. D., Fox, P. R., Haggstrom, J., Fuentes, V. L., … al. (2019). ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(3), 1127–1140. https://doi.org/10.1111/jvim.15488

Adin, C. A., Moga, J. L., Keene, B. W., Fogle, C. A., Hopkinson, H. R., Weyhrauch, C. A., … Rosoff, P. M. (2019, January 1). Clinical ethics consultation in a tertiary care veterinary teaching hospital. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 254, pp. 52–60. https://doi.org/10.2460/javma.254.1.52

Vollmar, C., Vollmar, A., Keene, B. W., Fox, P. R., Reese, S., & Kohn, B. (2019). Dilated cardiomyopathy in 151 Irish Wolfhounds: Characteristic clinical findings, life expectancy and causes of death. VETERINARY JOURNAL, 245, 15–21. https://doi.org/10.1016/j.tvjl.2018.12.018

Adin, D., DeFrancesco, T., Keene, B., Tou, S., Meurs, K., Atkins, C., … al. (2019). Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type. JOURNAL OF VETERINARY CARDIOLOGY, 21, 1–9. https://doi.org/10.1016/j.jvc.2018.11.002

Bartoszuk, U., Keene, B. W., Toaldo, M. B., Pereira, N., Summerfield, N., Matos, J. N., & Glans, T. M. (2019). Holter monitoring demonstrates that ventricular arrhythmias are common in cats with decompensated and compensated hypertrophic cardiomyopathy. VETERINARY JOURNAL, 243, 21–25. https://doi.org/10.1016/j.tvjl.2018.11.005

Vollmar, C., Vollmar, A., Keene, B., Fox, P. R., Reese, S., & Kohn, B. (2019). Irish wolfhounds with subclinical atrial fibrillation: progression of disease and causes of death. JOURNAL OF VETERINARY CARDIOLOGY, 24, 48–57. https://doi.org/10.1016/j.jvc.2019.05.004

Fox, P. R., Keene, B. W., Lamb, K., Schober, K. E., Chetboul, V., Fuentes, V. L., … Ohara, V. Y. T. (2019). Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy. JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(6), 2572–2586. https://doi.org/10.1111/jvim.15609

Meurs, K. M., Adin, D., K. O'Donnell, Keene, B. W., Atkins, C. E., DeFrancesco, T., & Tou, S. (2019). Myxomatous mitral valve disease in the miniature poodle: A retrospective study. VETERINARY JOURNAL, 244, 94–97. https://doi.org/10.1016/j.tvjl.2018.12.019

Ward, J., McLaughlin, A., Burzette, R., & Keene, B. (2019). The effect of a surgical safety checklist on complication rates associated with permanent transvenous pacemaker implantation in dogs. JOURNAL OF VETERINARY CARDIOLOGY, 22, 72–83. https://doi.org/10.1016/j.jvc.2018.11.001

Meurs, K., Friedenberg, S. G., Williams, B., Keene, B. W., Atkins, C. E., Adin, D., … al. (2018). Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration. VETERINARY JOURNAL, 232, 16–19. https://doi.org/10.1016/j.tvjl.2017.12.002

Fox, P. R., Keene, B. W., Lamb, K., Schober, K. A., Chetboul, V., Fuentes, V. L., … Ware, W. A. (2018). International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study. Journal of Veterinary Internal Medicine, 32(3), 930–943.

Boswood, A., Gordon, S. G., Haggstrom, J., Wess, G., Stepien, R. L., Oyama, M. A., … Church, W. M. (2018). Longitudinal analysis of quality of life, clinical, radiographic, echocardiographic, and laboratory variables in dogs with preclinical myxomatous mitral valve disease receiving pimobendan or placebo: The EPIC study. Journal of Veterinary Internal Medicine, 32(1), 72–85.

Rosoff, P. M., Moga, J., Keene, B., Adin, C., Fogle, C., Ruderman, R., … Weyhrauch, C. (2018). Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model. AMERICAN JOURNAL OF BIOETHICS, 18(2), 41–53. https://doi.org/10.1080/15265161.2017.1409824

Rosoff, P. M., Ruderman, R., Moga, J., Keene, B., Adin, C., Fogle, C., … Weyhrauch, C. (2018). Response to Open Peer Commentaries on "Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model". https://doi.org/10.1080/15265161.2017.1413439

Ward, J. L., Lisciandro, G. R., Keene, B. W., Tou, S. P., & DeFrancesco, T. C. (2017). Accuracy of point-of-care lung ultrasonography for the diagnosis of cardiogenic pulmonary edema in dogs and cats with acute dyspnea. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 250(6), 666–675. https://doi.org/10.2460/javma.250.6.666

Meurs, K. M., Stern, J. A., Atkins, C. E., Adin, D., Aona, B., Condit, J., … Woodruff, K. (2017). Angiotensin-converting enzyme activity and inhibition in dogs with cardiac disease and an angiotensin-converting enzyme polymorphism. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 18(4). https://doi.org/10.1177/1470320317737184

Boswood, A., Haggstrom, J., Gordon, S. G., Wess, G., Stepiens, R. L., Oyama, M. A., … Church, W. M. (2017). Effect of pimobendan in Dogs with preclinical myxomatous mitral valve disease and cardiomegaly: The EPIC study - A randomized clinical trial. Kleintier-Praxis, 62(2), 64–87.

Nolan, M. W., Arkans, M. M., LaVine, D., DeFrancesco, T., Myers, J. A., Griffith, E. H., … al. (2017). Pilot study to determine the feasibility of radiation therapy for dogs with right atrial masses and hemorrhagic pericardial effusion. Journal of Veterinary Cardiology, 19(2), 132–143. https://doi.org/10.1016/j.jvc.2016.12.001

Carter, J. E., Motsinger-Reif, A. A., Krug, W. V., & Keene, B. W. (2017). The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs. JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(4), 206–213. https://doi.org/10.5326/jaaha-ms-6512

McLaughlin, A. C., Ward, J., & Keene, B. W. (2016). Development of a Veterinary Surgical Checklist. ERGONOMICS IN DESIGN, 24(4), 27–34. https://doi.org/10.1177/1064804615621411

Boswood, A., Haggstrom, J., Gordon, S. G., Wess, G., Stepien, R. L., Oyama, M. A., … Church, W. M. (2016). Effect of Pimobendan in dogs with preclinical myxomatous mitral valve disease and cardiomegaly: The EPIC study-a randomized clinical trial. Journal of Veterinary Internal Medicine, 30(6), 1765–1779.

Palerme, J.-S., Jones, A. E., Ward, J. L., Balakrishnan, N., Linder, K. E., Breitschwerdt, E. B., & Keene, B. W. (2016). Infective endocarditis in 13 cats. Journal of Veterinary Cardiology, 18(3), 213–225. https://doi.org/10.1016/J.JVC.2016.04.003

Ward, J. L., DeFrancesco, T. C., Tou, S. P., Atkins, C. E., Griffith, E. H., & Keene, B. W. (2016). Outcome and survival in canine sick sinus syndrome and sinus node dysfunction: 93 cases (2002-2014). JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 199–212. https://doi.org/10.1016/j.jvc.2016.04.004

Balakrishnan, N., Alexander, K., Keene, B., Kolluru, S., Fauls, M. L., Rawdon, I., & Breitschwerdt, E. B. (2016). Successful treatment of mitral valve endocarditis in a dog associated with 'Actinomyces canis-like' infection. JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 271–277. https://doi.org/10.1016/j.jvc.2016.04.005

Schneider, S. M., Coleman, A. E., Guo, L.-J., Tou, S., Keene, B. W., & Kornegay, J. N. (2016). Suspected acute myocardial infarction in a dystrophin-deficient dog. NEUROMUSCULAR DISORDERS, 26(6), 361–366. https://doi.org/10.1016/j.nmd.2016.02.005

Friedenberg, S. G., Chdid, L., Keene, B., Sherry, B., Motsinger-Reif, A., & Meurs, K. M. (2016). Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy. AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(7), 693–699. https://doi.org/10.2460/ajvr.77.7.693

Oura, T. J., Young, A. N., Keene, B. W., Robertson, I. D., Jennings, D. E., & Thrall, D. E. (2015). A VALENTINE-SHAPED CARDIAC SILHOUETTE IN FELINE THORACIC RADIOGRAPHS IS PRIMARILY DUE TO LEFT ATRIAL ENLARGEMENT. VETERINARY RADIOLOGY & ULTRASOUND, 56(3), 245–250. https://doi.org/10.1111/vru.12221

Lantis, A. C., Ames, M. K., Atkins, C. E., Defrancesco, T. C., Keene, B. W., & Werre, S. R. (2015). Aldosterone breakthrough with benazepril in furosemide-activated renin-angiotensin-aldosterone system in normal dogs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 38(1), 65–73. https://doi.org/10.1111/jvp.12154

Hensley, M. T., Andrade, J., Keene, B., Meurs, K., Tang, J. N., Wang, Z. G., … al. (2015). Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts. Journal of Cellular and Molecular Medicine, 19(8), 1805–1813. https://doi.org/10.1111/jcmm.12585

Ward, J. L., DeFrancesco, T. C., Tou, S. P., Atkins, C. E., Griffith, E. H., & Keene, B. W. (2015). Complication Rates Associated with Transvenous Pacemaker Implantation in Dogs with High-Grade Atrioventricular Block Performed During versus After Normal Business Hours. JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(1), 157–163. https://doi.org/10.1111/jvim.12512

Keene, B. W., & Tou, S. P. (2015). Cor triatriatum. Veterinary Image-Guided Interventions, 604–609.

Meurs, K. M., Stern, J. A., Reina-Doreste, Y., Maran, B. A., Chdid, L., Lahmers, S., … Mealey, K. L. (2015). Impact of the canine double-deletion beta 1 adrenoreceptor polymorphisms on protein structure and heart rate response to atenolol, a beta 1-selective beta-blocker. PHARMACOGENETICS AND GENOMICS, 25(9), 427–431. https://doi.org/10.1097/fpc.0000000000000152

Hogan, D. F., Fox, P. R., Jacob, K., Keene, B., Laste, N. J., Rosenthal, S., … Weng, H.-Y. (2015). Secondary prevention of cardiogenic arterial thromboembolism in the cat: the double-blind, randomized, positive-controlled feline arterial thromboembolism; clopidogrel vs. aspirin trial (FAT CAT). JOURNAL OF VETERINARY CARDIOLOGY, 17, S306–S317. https://doi.org/10.1016/j.jvc.2015.10.004

Reina-Doreste, Y., Stern, J. A., Keene, B. W., Tou, S. P., Atkins, C. E., DeFrancesco, T. C., … Meurs, K. M. (2014). Case-control study of the effects of pimobendan on survival time in cats with hypertrophic cardiomyopathy and congestive heart failure. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 245(5), 534–539. https://doi.org/10.2460/javma.245.5.534

Edwards, T. H., Coleman, A. E., Brainard, B. M., DeFrancesco, T. C., Hansen, B. D., Keene, B. W., & Koenig, A. (2014). Outcome of positive-pressure ventilation in dogs and cats with congestive heart failure: 16 cases (1992-2012). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 24(5), 586–593. https://doi.org/10.1111/vec.12230

Meurs, K. M., Stern, J. A., Sisson, D. D., Kittleson, M. D., Cunningham, S. M., Ames, M. K., … Tou, S. P. (2013). Association of Dilated Cardiomyopathy with the Striatin Mutation Genotype in Boxer Dogs. JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1437–1440. https://doi.org/10.1111/jvim.12163

Kane, A. M., DeFrancesco, T. C., Boyle, M. C., Malarkey, D. E., Ritchey, J. W., Atkins, C. E., … Keene, B. W. (2013). Cardiac structure and function in female carrier's of a canine model of Duchenne muscular dystrophy. RESEARCH IN VETERINARY SCIENCE, 94(3), 610–617. https://doi.org/10.1016/j.rvsc.2012.09.027

Stern, J. A., Tou, S. P., Barker, P. C. A., Hill, K. D., Lodge, A. J., Mathews, K. G., & Keene, B. W. (2013). Hybrid cutting balloon dilatation for treatment of cor triatriatum sinister in a cat. JOURNAL OF VETERINARY CARDIOLOGY, 15(3), 205–210. https://doi.org/10.1016/j.jvc.2013.03.001

Visser, L. C., Keene, B. W., Mathews, K. G., Browne, W. J., & Chanoit, G. (2013). Outcomes and Complications Associated With Epicardial Pacemakers in 28 Dogs and 5 Cats. VETERINARY SURGERY, 42(5), 544–550. https://doi.org/10.1111/j.1532-950x.2013.12020.x

Meurs, K. M., Lahmers, S., Keene, B. W., White, S. N., Oyama, M. A., Mauceli, E., & Lindblad-Toh, K. (2012). A splice site mutation in a gene encoding for PDK4, a mitochondrial protein, is associated with the development of dilated cardiomyopathy in the Doberman pinscher. HUMAN GENETICS, 131(8), 1319–1325. https://doi.org/10.1007/s00439-012-1158-2

Kornegay, J. N., Bogan, J. R., Bogan, D. J., Childers, M. K., Li, J., Nghiem, P., … Styner, M. A. (2012). Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mammalian Genome, 23(1-2), 85–108.

Stern, J. A., Tobias, J. R., & Keene, B. W. (2012). Complete atrioventricular block secondary to cardiac lymphoma in a dog. Journal of Veterinary Cardiology, 14(4), 537–539. https://doi.org/10.1016/j.jvc.2012.04.007

LeBlanc, N., DeFrancesco, T. C., Adams, A. K., Atkins, C. E., Tou, S. P., Fudge, J. C., & Keene, B. W. (2012). Cutting balloon catheterization for interventional treatment of cor triatriatum dexter: 2 Cases. Journal of Veterinary Cardiology, 14(4), 525–530. https://doi.org/10.1016/j.jvc.2012.04.006

Chanoit, G., Mathews, K. G., Keene, B. W., Small, M. T., & Linder, K. (2012). Surgical treatment of a pulmonary artery vascular hamartoma in a dog. Journal of the American Veterinary Medical Association, 240(7), 858–862. https://doi.org/10.2460/javma.240.7.858

Tou, S. P., DeFrancesco, T. C., & Keene, B. W. (2011, July 1). ECG of the Month. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 239, pp. 55–57. https://doi.org/10.2460/javma.239.1.55

Fox, P. R., Rush, J. E., Reynolds, C. A., DeFrancesco, T. C., Keene, B. W., Atkins, C. E., … Lefbom, B. K. (2011). Multicenter Evaluation of Plasma N-Terminal Probrain Natriuretic Peptide (NT-pro BNP) as a Biochemical Screening Test for Asymptomatic (occult) Cardiomyopathy in Cats. Journal of Veterinary Internal Medicine, 25(5), 1010–1016.

Tou, S. P., Keene, B. W., & Barker, P. C. A. (2011). Pulmonary atresia and ventricular septal defect with aortopulmonary collaterals in an adult dog. Journal of Veterinary Cardiology, 13(4), 271–275. https://doi.org/10.1016/j.jvc.2011.09.002

Perez, C., Hummel, J. B., Keene, B. W., Maggi, R. G., Diniz, P. P. V. P., & Breitschwerdt, E. B. (2010). Successful treatment ofBartonella henselaeendocarditis in a cat. Journal of Feline Medicine and Surgery, 12(6), 483–486. https://doi.org/10.1016/j.jfms.2009.12.018

Sayer, M. B., Atkins, C. E., Fujii, Y., Adams, A. K., DeFrancesco, T. C., & Keene, B. W. (2009). Acute Effect of Pimobendan and Furosemide on the Circulating Renin-Angiotensin-Aldosterone System in Healthy Dogs. JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(5), 1003–1006. https://doi.org/10.1111/j.1939-1676.2009.0367.x

Atkins, C., Bonagura, J., Ettinger, S., Fox, P., Gordon, S., Haggstrom, J., … Stepien, R. (2009). [Review of Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(6), 1142–1150. https://doi.org/10.1111/j.1939-1676.2009.0392.x

Fox, P. R., Oyama, M. A., Reynolds, C., Rush, J. E., DeFrancesco, T. C., Keene, B. W., … Hogan, D. F. (2009). Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats. Journal of Veterinary Cardiology, 11(Supplement 1), S51–S61. https://doi.org/10.1016/j.jvc.2008.12.001

Beddies, G., Fox, P. R., Papich, M. D., Kanikanti, V.-R., Krebber, R., & Keene, B. W. (2008). Comparison of the pharmacokinetic properties of bisoprolol and carvedilol in healthy dogs. AMERICAN JOURNAL OF VETERINARY RESEARCH, 69(12), 1659–1663. https://doi.org/10.2460/ajvr.69.12.1659

Cunha, D. N. Q., Buccellato, M., Keene, B. W., Rajala-Schultz, P., Nishijima, Y., Ozkanlar, Y., & Hamlin, R. L. (2008). Electrocardiographic, hematologic, histopathologic, and recovery characteristics from repeated morphine-chloralose anesthesia in dogs. International Journal of Applied Research in Veterinary Medicine, 6(3), 191–199.

Finster, S. T., DeFrancesco, T. C., Atkins, C. E., Hansen, B. D., & Keene, B. W. (2008, October). Supraventricular tachycardia in dogs: 65 cases (1990-2007). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 18, pp. 503–510. https://doi.org/10.1111/j.1476-4431.2008.00346.x

Small, M. T., Atkins, C. E., Gordon, S. G., Birkenheuer, A. J., Booth-Sayer, M. A., Keene, B. W., … Miller, M. W. (2008). Use of a nitinol gooseneck snare catheter for removal of adult Dirofilaria immitis in two cats. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 233(9), 1441–1445. https://doi.org/10.2460/javma.233.9.1441

Wood, M. W., Vaden, S., Cerda-Gonzalez, S., & Keene, B. (2007). Cystoscopic-guided balloon dilation of a urethral stricture in a female dog. Canadian Veterinary Journal, 48(7), 731–733.

Adams, A. K., & Keene, B. W. (2007, July 15). ECG of the month. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 231, pp. 209–211. https://doi.org/10.2460/javma.231.2.209

Gardner, S. Y., Atkins, C. E., Rausch, W. P., DeFrancesco, T. C., Chandler, D. W., & Keene, B. W. (2007). Estimation of 24-h aldosterone secretion in the dog using the urine aldosterone: Creatinine ratio. Journal of Veterinary Cardiology, 9(1), 1–7. https://doi.org/10.1016/j.jvc.2006.11.001

Hansen, B. D., Lascelles, D. X., Keene, B. W., Adams, A. K., & Thomson, A. E. (2007). Evaluation of an accelerometer for at-home monitoring of spontaneous activity in dogs. AMERICAN JOURNAL OF VETERINARY RESEARCH, 68(5), 468–475. https://doi.org/10.2460/ajvr.68.5.468

Kuppinger, O., Fischer, E., Sum, S., Hirschberger, J., Rausch, W. P., Keene, B. W., … Schulz, R. (2007). Lack of GNB3 exon 9 polymorphism in primary hypertensive and normotensive dogs. VETERINARY RECORD, 160(19), 654–657. https://doi.org/10.1136/vr.160.19.654

DeFrancesco, T. C., Rush, J. E., Rozanski, E. A., Hansen, B. D., Keene, B. W., Moore, D. T., & Atkins, C. E. (2007). Prospective clinical evaluation of an ELISA B-type natriuretic peptide assay in the diagnosis of congestive heart failure in dogs presenting with cough or dyspnea. JOURNAL OF VETERINARY INTERNAL MEDICINE, 21(2), 243–250. https://doi.org/10.1892/0891-6640(2007)21[243:PCEOAE]2.0.CO;2

Atkins, C. E., Keene, B. W., Brown, W. A., Coats, J. R., Crawford, M. A., DeFrancesco, T. C., … Straus, J. H. (2007). Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency. Journal of the American Veterinary Medical Association, 231(7), 1061–1069. https://doi.org/10.2460/javma.231.7.1061

Atkins, C. E., Rausch, W. P., Gardner, S. Y., Defrancesco, T. C., Keene, B. W., & Levine, J. F. (2007). The effect of amlodipine and the combination of amlodipine and enalapril on the renin-angiotensin-aldosterone system in the dog. Journal of Veterinary Pharmacology and Therapeutics, 30(5), 394–400. https://doi.org/10.1111/j.1365-2885.2007.00894.x

Kijtawornrat, A., Ozkanlar, Y., Keene, B. W., Roche, B. M., Hamlin, D. M., & Hamlin, R. L. (2006). Assessment of drug-induced QT interval prolongation in conscious rabbits. Journal of Pharmacological and Toxicological Methods, 53(2), 168–173. https://doi.org/10.1016/j.vascn.2005.04.013

Kelly, P., Rolain, J. M., Maggi, R., Sontakke, S., Keene, B., Hunter, S., … al. (2006). Bartonella quintana Endocarditis in Dogs. Emerging Infectious Diseases, 12(12), 1869–1872. https://doi.org/10.3201/eid1212.060724

Fujii, Y., Keene, B. W., Mathews, K. G., Atkins, C. E., Defrancesco, T. C., Hardie, E. M., & Wakao, Y. (2006). Coil occlusion of residual shunts after surgical closure of patent ductus arteriosus. VETERINARY SURGERY, 35(8), 781–785. https://doi.org/10.1111/j.1532-950X.2006.00222.x

Kijtawornrat, A., Nishijima, Y., Roche, B. M., Keene, B. W., & Hamlin, R. L. (2006). Use of a failing rabbit heart as a model to predict torsadogenicity. TOXICOLOGICAL SCIENCES, 93(1), 205–212. https://doi.org/10.1093/toxsci/kfl025

Ozkanlar, Y., Kijtawornrat, A., Hamlin, R. L., Keene, B. W., & Roche, B. M. (2005). Acute cardiovascular effects of tacrolimus in the isolated guinea pig heart. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(3), 313–316. https://doi.org/10.1111/j.1365-2885.2005.00631.x

Cesta, M. F., Baty, C. J., Keene, B. W., Smoak, I. W., & Malarkey, D. E. (2005). Pathology of end-stage remodeling in a family of cats with hypertrophic cardiomyopathy. VETERINARY PATHOLOGY, 42(4), 458–467. https://doi.org/10.1354/vp.42-4-458

Hamlin, R. L., Kijtawornrat, A., & Keene, B. W. (2004). How many cardiac cycles must be measured to permit accurate RR, QT, and QTc estimates in conscious dogs? Journal of Pharmacological and Toxicological Methods, 50(2), 103–108. https://doi.org/10.1016/j.vascn.2004.03.013

Olby, N., Harris, T., Burr, J., Munana, K., Sharp, N., & Keene, B. (2004). Recovery of pelvic limb function in dogs following acute intervertebral disc herniations. JOURNAL OF NEUROTRAUMA, 21(1), 49–59. https://doi.org/10.1089/089771504772695940

Hamlin, R. L., Cruze, C. A., Mittelstadt, S. W., Kijtawornrat, A., Keene, B. W., Roche, B. M., … Arnold, T. (2004). Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc. Journal of Pharmacological and Toxicological Methods, 49(1), 15–23. https://doi.org/10.1016/j.vascn.2003.08.003

Glaus, T. M., Hassig, M., & Keene, B. W. (2003). Accuracy of heart rate obtained by auscultation in atrial fibrillation. JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(3), 237–239. https://doi.org/10.5326/0390237

DeFrancesco, T. C., Hansen, B. D., Atkins, C. E., Sidley, J. A., & Keene, B. W. (2003). Noninvasive transthoracic temporary cardiac pacing in dogs. JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 17, pp. 663–667. https://doi.org/10.1892/0891-6640(2003)017<0663:NTTCPI>2.3.CO;2

Hamlin, R. L., Kijtawornrat, A., Keene, B. W., & Hamlin, D. M. (2003). QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles. TOXICOLOGICAL SCIENCES, 76(2), 437–442. https://doi.org/10.1093/toxsci/kfg254

Rausch, W. P., & Keene, B. W. (2003). Spontaneous resolution of an isolated ventricular septal defect in a dog. JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 223(2), 219–220. https://doi.org/10.2460/javma.2003.223.219

Meurs, K. M., Spier, A. W., Wright, N. A., Atkins, C. E., DeFrancesco, T., Gordon, S. G., … al. (2002). Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. Journal of the American Veterinary Medical Association, 221(4), 522–527. https://doi.org/10.2460/javma.2002.221.522

Atkins, C. E., Brown, W. A., Coats, J. R., Crawford, M. A., DeFrancesco, T. C., Edwards, J., … Straus, J. (2002). Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation. Journal of the American Veterinary Medical Association, 221(5), 654–658. https://doi.org/10.2460/javma.2002.221.654

Pressler, B. M., Rotstein, D. S., Law, J. M., Rosol, T. J., LeRoy, B., Keene, B. W., & Jackson, M. W. (2002). Hypercalcemia and high parathyroid hormone-related protein concentration associated with malignant melanoma in a dog. JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 221(2), 263-+. https://doi.org/10.2460/javma.2002.221.263

Sidley, J. A., Atkins, C. E., Keene, B. W., & DeFrancesco, T. C. (2002). Percutaneous Balloon Pericardiotomy as a Treatment for Recurrent Pericardial Effusion in 6 Dogs. Journal of Veterinary Internal Medicine, 16(5), 541–546. https://doi.org/10.1892/0891-6640(2002)016<0541:PBPAAT>2.3.CO;2

Little, D., Keene, B. W., Bruton, C., Smith, L. J., Powell, S., & Jones, S. L. (2002). Percutaneous retrieval of a jugular catheter fragment from the pulmonary artery of a foal. JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 220(2), 212–214. https://doi.org/10.2460/javma.2002.220.212

DeFrancesco, T. C., Atkins, C. E., Keene, B. W., Coats, JR, & Hauck, M. L. (2002). Prospective clinical evaluation of serum cardiac troponin T in dogs admitted to a veterinary teaching hospital. JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 553–557. https://doi.org/10.1892/0891-6640(2002)016<0553:PCEOSC>2.3.CO;2

Olby, N. J., De Risio, L., Munana, K. R., Wosar, M. A., Skeen, T. M., Sharp, N. J. H., & Keene, B. W. (2001). Development of a functional scoring system in dogs with acute spinal cord injuries. AMERICAN JOURNAL OF VETERINARY RESEARCH, 62(10), 1624–1628. https://doi.org/10.2460/ajvr.2001.62.1624

Mc Entee, K., Flandre, T., Dessy, C., Desmecht, D., Clercx, C., Balligand, M., … Keene, B. (2001). Metabolic and structural abnormalities in dogs with early left ventricular dysfunction induced by incessant tachycardia. AMERICAN JOURNAL OF VETERINARY RESEARCH, 62(6), 889–894. https://doi.org/10.2460/ajvr.2001.62.889

Baty, C. J., Malarkey, D. E., Atkins, C. E., DeFrancesco, T. C., Sidley, J., & Keene, B. W. (2001). Natural history of hypertrophic cardiomyopathy and aortic thromboembolism in a family of domestic shorthair cats. JOURNAL OF VETERINARY INTERNAL MEDICINE, 15(6), 595–599. https://doi.org/10.1892/0891-6640(2001)015<0595:NHOHCA>2.3.CO;2

DeFrancesco, T. C., Atkins, C. E., Miller, M. W., Meurs, K. M., & Keene, B. W. (2001). Use of echocardiography for the diagnosis of heartworm disease in cats: 43 cases (1985-1997). Journal of the American Veterinary Medical Association, 218(1), 66–69. https://doi.org/10.2460/javma.2001.218.66

Atkins, C. E., DeFrancesco, T. C., Coats, JR, Sidley, J. A., & Keene, B. W. (2000). Heartworm infection in cats: 50 cases (1985-1997). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 217(3), 355–358. https://doi.org/10.2460/javma.2000.217.355

Keene, B. W. (2000). Towards evidence-based veterinary medicine. JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 118–119. https://doi.org/10.1111/j.1939-1676.2000.tb02223.x

Schatzberg, S., Olby, N., Steingold, S., Keene, B., Atkins, C., Meurs, K., … Sharp, N. (1999). A polymerase chain reaction screening strategy for the promoter of the canine dystrophin gene. American Journal of Veterinary Research, 60(9), 1040–1046.

Alexander, L. K., Keene, B. W., Yount, B. L., Geratz, J. D., Small, J. D., & Baric, R. S. (1999). ECG changes after rabbit coronavirus infection. JOURNAL OF ELECTROCARDIOLOGY, 32(1), 21–32. https://doi.org/10.1016/S0022-0736(99)90018-3

Atkins, C. E., DeFrancesco, T. C., Miller, M. W., Meurs, K. M., & Keene, B. (1998). Prevalence of heartworm infection in cats with signs of cardiorespiratory abnormalities. Journal of the American Veterinary Medical Association, 212(4), 517–520.

Carroll, G. L., Keene, B. W., & Forrest, L. J. (1997). Asystole associated with iohexol myelography in a dog. VETERINARY RADIOLOGY & ULTRASOUND, 38(4), 284–287. https://doi.org/10.1111/j.1740-8261.1997.tb00857.x

Kittleson, M. D., Keene, B., Pion, P. D., Loyer, C. G., Beardow, A. W., Knight, D. H., … Ware, W. A. (1997). Results of the Multicenter Spaniel Trial (MUST): Taurine- and carnitine-responsive dilated cardiomyopathy in American cocker spaniels with decreased plasma taurine concentration. JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11, pp. 204–211. https://doi.org/10.1111/j.1939-1676.1997.tb00092.x

Keene, B. W. (1996). Management of canine dilated cardiomyopathy. Canine Practice (Santa Barbara, Calif. : 1990), 21(1), 27.

Keene, B. W., & Flammer, K. (1991). ECG of the month. Journal of the American Veterinary Medical Association, 198(3), 408.