Works (23)

Updated: February 15th, 2024 05:01

2024 article

ACVIM consensus statement on diagnosis and management of urinary incontinence in dogs

Kendall, A., Byron, J. K., Westropp, J. L., Coates, J. R., Vaden, S., Adin, C., … Berent, A. (2024, January 13). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 1.

By: A. Kendall n, J. Byron*, J. Westropp*, J. Coates*, S. Vaden n, C. Adin*, G. Oetelaar, J. Bartges* ...

author keywords: canine; incontinence; urinary
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 12, 2024

2023 journal article

A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans

NPJ REGENERATIVE MEDICINE, 8(1).

By: W. Zhang*, X. Wang*, G. Lanzoni, E. Wauthier*, S. Simpson n, J. Ezzell, A. Allen*, C. Suitt ...

TL;DR: Hepato/pancreatic multipotentiality was demonstrated by the stem/progenitors’ responses under distinct ex vivo conditions or in vivo when patch grafted as organoids onto the liver versus the pancreas. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2021 journal article

Patch grafting, strategies for transplantation of organoids into solid organs such as liver

BIOMATERIALS, 277.

By: W. Zhang*, G. Lanzoni*, H. Hani*, D. Overi*, V. Cardinale*, S. Simpson n, W. Pitman*, A. Allen* ...

author keywords: Liver; Biliary tree; Stem/progenitors; Cell therapies; Grafting; Matrix-metalloproteinases (MMPs); Hyaluronans
MeSH headings : Animals; Cell Differentiation; Hepatocytes; Liver; Organoids; Stem Cells; Swine
TL;DR: RNA-seq analyses revealed that engraftment correlated with expression of matrix-metalloproteinases (MMPs), especially secreted isoforms that were found expressed strongly by organoids, less so by MSCs, and minimally, if at all, by adult cells. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 4, 2021

2019 journal article

Computed Tomography for the Diagnosis and Characterization of Dermoid Sinuses in Two Dogs

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 55(4).

By: S. Jones n, C. Adin n, E. Thompson n, I. Robertson n & R. Rivas n

MeSH headings : Animals; Dermoid Cyst / diagnosis; Dermoid Cyst / pathology; Dermoid Cyst / surgery; Dermoid Cyst / veterinary; Dog Diseases / diagnosis; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Laminectomy / veterinary; Male; Spinal Neoplasms / diagnosis; Spinal Neoplasms / pathology; Spinal Neoplasms / veterinary; Tomography, X-Ray Computed / veterinary
TL;DR: These cases show that single-phase contrast CT was accurate in characterizing the extent of the dermoid sinus without adjunctive tests or more invasive diagnostics, avoiding the risks associated with myelography or fistulography and the expense of MRI. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 1, 2019

2019 journal article

Cross-Sectional Assessment of the Emotional Intelligence of Fourth-Year Veterinary Students and Veterinary House Officers in a Teaching Hospital

JOURNAL OF VETERINARY MEDICAL EDUCATION, 47(2), 193–201.

By: D. Adin*, K. Royal* & C. Adin*

author keywords: emotions; expression; empathy; stress; resident; training
MeSH headings : Cross-Sectional Studies; Education, Veterinary; Emotional Intelligence; Hospitals, Teaching / statistics & numerical data; Humans; Students / psychology; Students / statistics & numerical data
TL;DR: B baseline EI scores of 4th-year veterinary students, interns, and residents at a teaching hospital were similar to, but uniformly lower than, those of other professionals and did not increase with training level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 14, 2020

2018 article

Clinical ethics consultation in a tertiary care veterinary teaching hospital

Adin, C. A., Moga, J. L., Keene, B. W., Fogle, C. A., Hopkinson, H. R., Weyhrauch, C. A., … Rosoff, P. M. (2019, January 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 254, pp. 52–60.

By: C. Adin*, J. Moga*, B. Keene*, C. Fogle*, H. Hopkinson*, C. Weyhrauch*, S. Marks*, R. Ruderman, P. Rosoff*

MeSH headings : Animal Rights; Animals; Ethics Consultation; Hospitals, Teaching; Humans; Tertiary Healthcare; United States
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 14, 2019

2018 review

Duty hours restriction for our surgical trainees: An ethical obligation or a bad idea?

[Review of ]. VETERINARY SURGERY, 47(3), 327–332.

By: C. Adin n, C. Fogle n & S. Marks n

MeSH headings : Accreditation; Education, Veterinary / ethics; Humans; Internship and Residency / ethics; North Carolina; Personnel Staffing and Scheduling / ethics; Quality of Life; Surveys and Questionnaires; Veterinary Medicine / ethics; Work Schedule Tolerance
TL;DR: Vets must consider post-DVM veterinary training guidelines that maintain patient care with a good learning environment for interns and residents as they face work-related stress as a result of extended working hours, on-call duty, and an increasingly complex caseload. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model

AMERICAN JOURNAL OF BIOETHICS, 18(2), 41–53.

By: P. Rosoff*, J. Moga n, B. Keene n, C. Adin n, C. Fogle n, R. Ruderman*, H. Hopkinso n, C. Weyhrauch n

author keywords: end-of-life issues; ethics committees; professional-patient relationship
MeSH headings : Animal Welfare / ethics; Animals; Ethics Consultation; Euthanasia, Animal / ethics; Humans; Professional Competence; Tertiary Healthcare / ethics; Veterinarians / ethics; Veterinary Medicine / ethics
TL;DR: The staff of the North Carolina State University Veterinary Hospital, a specialty academic teaching institution, wanted to investigate whether similar success could be achieved in the tertiary care veterinary setting, and the background and rationale for this method were discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 personal communication

Response to Open Peer Commentaries on "Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model"

By: P. Rosoff*, R. Ruderman*, J. Moga n, B. Keene n, C. Adin n, C. Fogle n, H. Hopkinson n, C. Weyhrauch n

MeSH headings : Ethics Committees, Clinical; Ethics Consultation; Humans; Morals; Tertiary Healthcare
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Selective Osmotic Shock for Islet Isolation in the Cadaveric Canine Pancreas

CELL TRANSPLANTATION, 27(3), 542–550.

By: E. Thompson n, J. Sollinger n, E. Opara* & C. Adin n

author keywords: islet isolation; selective osmotic shock; GLUT2; canine; cadaveric
MeSH headings : Animals; Cell Death / physiology; Cell Survival / physiology; Dogs; Female; Glucose / pharmacology; Glucose Transporter Type 2 / metabolism; Islets of Langerhans / metabolism; Male; Osmotic Pressure / drug effects; Osmotic Pressure / physiology
TL;DR: A novel islet isolation protocol utilizing high concentrations of glucose to cause selective osmotic shock (SOS) provides a widely available means for researchers to isolate canine islets for use in islet transplantation or in studies of canine islet physiology. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Aldehyde dehydrogenase 1 a1 regulates energy metabolism in adipocytes from different species

XENOTRANSPLANTATION, 24(5).

By: K. Yang*, C. Adin n, Q. Shen*, L. Lee*, L. Yu*, P. Fadda*, A. Samogyi*, K. Ham* ...

author keywords: adipocytes; adipogenesis; beige; bright adipocytes; brown; energy balance; neutrophil gelatinase-associated; lipocalin; obesity; transplantation; vitamin A; xenocultures
MeSH headings : Adipocytes / metabolism; Adipogenesis / physiology; Aldehyde Dehydrogenase 1 Family; Animals; Cell Differentiation / physiology; Dogs; Energy Metabolism / physiology; Isoenzymes / metabolism; Mice; Obesity / therapy; Retinal Dehydrogenase / metabolism; Thermogenesis / physiology; Transplantation, Heterologous / methods; Vitamin A / metabolism
TL;DR: The role Aldh1a1 in regulation of lipid metabolism in xenocultures is tested and it is shown thaticient retinoic acid production in aldehyde dehydrogenase 1 A1 (Aldh 1a1) knockout adipocytes (KO) inhibits adipogenesis and increases thermogenesis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Associations of patient characteristics, disease stage, and biopsy technique with the diagnostic quality of core needle renal biopsy specimens from dogs with suspected kidney disease

Journal of the American Veterinary Medical Association, 252(1), 67–74.

By: L. Crivellenti, R. Cianciolo, T. Wittum, G. Lees & C. Adin*

MeSH headings : Animals; Biopsy, Needle / standards; Biopsy, Needle / veterinary; Cross-Sectional Studies; Databases, Factual; Dog Diseases / pathology; Dogs; Female; Kidney Diseases / pathology; Kidney Diseases / veterinary; Male; Predictive Value of Tests; Retrospective Studies; Severity of Illness Index; Ultrasonography, Interventional / veterinary
TL;DR: Findings suggested that ultrasound-guided biopsy with a 16-gauge needle should maximize the diagnostic quality of renal biopsy specimens from dogs with suspected kidney disease, while avoiding potential adverse effects caused by larger needles. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Nano-Encapsulation of Bilirubin in Pluronic F127-Chitosan Improves Uptake in beta Cells and Increases Islet Viability and Function after Hypoxic Stress

CELL TRANSPLANTATION, 26(10), 1703–1715.

author keywords: diabetes; islet; transplant; bilirubin; nanoparticle; encapsulation
MeSH headings : Animals; B-Lymphocytes / metabolism; Bilirubin / metabolism; Cell Hypoxia; Chitosan / analogs & derivatives; Chitosan / metabolism; Humans; Islets of Langerhans Transplantation / methods; Mice; Nanoparticles / metabolism
TL;DR: Delivery of bilirubin using pluronic F127–chitosan NP improves uptake by murine islets compared to fBR and offers dose-dependent protective effects following hypoxic stress. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Laparoscopic Placement and Urodynamic Effects of an Artificial Urethral Sphincter in Cadaveric Dogs

VETERINARY SURGERY, 45, O20–O27.

By: E. Luckring n, K. Ham*, C. Adin n, M. McLoughlin* & J. Stull*

MeSH headings : Animals; Cadaver; Dogs; Female; Laparoscopy / methods; Laparoscopy / veterinary; Urethra / physiology; Urethra / surgery; Urinary Sphincter, Artificial / veterinary; Urodynamics
TL;DR: Laroscopic placement of an AUS can be performed successfully in cadaver dogs, improved urethral pressure profile parameters, and visibly occluded the urethrals lumen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Physiologic Doses of Bilirubin Contribute to Tolerance of Islet Transplants by Suppressing the Innate Immune Response

CELL TRANSPLANTATION, 26(1), 11–21.

By: C. Adin n, Z. VanGundy*, T. Papenfuss*, F. Xu*, M. Ghanem*, J. Lakey*, G. Hadley*

author keywords: Islet; Damage-associated molecular patterns (DAMPs); HMGB1; Bilirubin; Innate immune response
MeSH headings : Animals; Bilirubin / therapeutic use; Cell Survival / drug effects; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; HMGB1 Protein / metabolism; Immune Tolerance / drug effects; Immune Tolerance / immunology; Immunity, Innate / drug effects; Immunity, Innate / immunology; Immunoassay; Islets of Langerhans Transplantation / immunology; Islets of Langerhans Transplantation / methods; Mice
TL;DR: Exogenous bilirubin supplementation showed cytoprotective and antioxidant effects in a relevant model of islet isolation and hypoxic stress, suggesting that the use of this natural antioxidant may provide a method of preconditioning to improve outcomes after allograft transplantation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Radical Cystectomy and Cutaneous Ureterostomy in 4 Dogs with Trigonal Transitional Cell Carcinoma: Description of Technique and Case Series

VETERINARY SURGERY, 46(1), 111–119.

By: R. Huppes, L. Crivellenti*, A. De Nardi*, B. Lima*, C. Cintra*, J. Costa Castro*, C. Adin n

MeSH headings : Animals; Carcinoma, Transitional Cell / surgery; Carcinoma, Transitional Cell / veterinary; Cystectomy / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Male; Retrospective Studies; Treatment Outcome; Ureterostomy / veterinary; Urinary Bladder Neoplasms / surgery; Urinary Bladder Neoplasms / veterinary
TL;DR: Radical cystectomy with cutaneous ureterostomy is a viable salvage procedure for urinary diversion after Cystectomy in dogs with invasive bladder neoplasia and was considered acceptable by most owners. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Suture-Free Ureterovesical Anastomosis Using a Microvascular Anastomosis System: Canine Cadaveric Study

VETERINARY SURGERY, 44(6), 731–736.

By: J. Bertran*, V. Wavreille*, K. Ham*, M. McLoughlin* & C. Adin*

MeSH headings : Anastomosis, Surgical / methods; Anastomosis, Surgical / veterinary; Animals; Cadaver; Dogs / surgery; Equipment Failure Analysis / standards; Pressure; Ureter / surgery
TL;DR: This study demonstrated the feasibility of a suture-free ureterovesical anastomosis in the canine cadaver using a commercially available MAS and improved the bursting resistance of both techniques but there was no difference between the techniques covered by an EVSMT. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Pharmacokinetics and pharmacodynamics of the glucagon-like peptide-1 analog liraglutide in healthy cats

Domestic Animal Endocrinology, 51, 114–121.

author keywords: Feline; Diabetes; Insulin; Glucagon; Incretin
MeSH headings : Animals; Appetite / drug effects; Blood Glucose / analysis; Cats / blood; Cats / metabolism; Female; Glucagon / blood; Glucagon-Like Peptide 1 / analogs & derivatives; Glucose / administration & dosage; Glucose Clamp Technique; Hyperglycemia / blood; Hypoglycemic Agents; Insulin / blood; Liraglutide / administration & dosage; Liraglutide / pharmacokinetics; Liraglutide / pharmacology; Male; Weight Loss / drug effects
TL;DR: Liraglutide has similar effects and pharmacokinetics profile in cats to those reported in people, and once daily dosing might be feasible; however, significant effects on appetite and weight loss may necessitate dosage or dosing frequency reductions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: February 21, 2020

2014 journal article

Pharmacology of the glucagon-like peptide-1 analog exenatide extended-release in healthy cats

Domestic Animal Endocrinology, 51, 78–85.

author keywords: Feline; Exenatide; Incretin; Diabetes; Insulin; Glucagon
MeSH headings : Animals; Blood Glucose / analysis; Cat Diseases / drug therapy; Cats; Diabetes Mellitus / drug therapy; Diabetes Mellitus / veterinary; Drug Synergism; Exenatide; Fasting; Glucagon / blood; Glucagon-Like Peptide 1 / analogs & derivatives; Glucagon-Like Peptide-1 Receptor / agonists; Glucose Clamp Technique; Hypoglycemic Agents / pharmacokinetics; Hypoglycemic Agents / pharmacology; Injections, Subcutaneous; Insulin / blood; Microspheres; Peptides / administration & dosage; Peptides / pharmacokinetics; Peptides / pharmacology; Venoms / administration & dosage; Venoms / pharmacokinetics; Venoms / pharmacology
TL;DR: Exenatide ER was safe and effective in improving glucose tolerance 3 wk after a single injection and further evaluation is needed to determine its safety, efficacy, and duration of action in diabetic cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: February 21, 2020

2013 journal article

Evaluation of a high-yield technique for pancreatic islet isolation from deceased canine donors

Domestic Animal Endocrinology, 47, 119–126.

By: D. Vrabelova*, C. Adin*, A. Kenzig*, C. Gilor*, F. Xu*, J. Buss*, A. Rajab*

author keywords: Pancreas; Canine islets; Digestion; Ricordi chamber
MeSH headings : Animals; Cadaver; Cell Separation / methods; Cell Separation / veterinary; Dogs; Islets of Langerhans / physiology; Tissue Donors
TL;DR: Clinical relevant islet yield and quality can be obtained from deceased canine donors with the use of standard laboratory equipment, and purity and viability of the isolated islets were comparable with those achieved in human islet transplantation program. (via Semantic Scholar)
Source: Crossref
Added: February 21, 2020

2011 journal article

Complications of Ovariohysterectomy and Orchiectomy in Companion Animals

Veterinary Clinics of North America: Small Animal Practice, 41(5), 1023–1039.

By: C. Adin*

author keywords: Spay; Neuter; Ovariohysterectomy; Orchiectomy; Castration; Complications
MeSH headings : Animals; Cat Diseases / surgery; Cats; Dog Diseases / surgery; Dogs; Female; Hysterectomy / veterinary; Male; Orchiectomy / veterinary; Ovariectomy / veterinary; Postoperative Complications / prevention & control; Postoperative Complications / veterinary
TL;DR: The reported complications encountered in elective sterilization surgery in companion animals, with a special focus on early detection and prevention are reviewed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: December 29, 2020

2011 journal article

Complications of Upper Urinary Tract Surgery in Companion Animals

Veterinary Clinics of North America: Small Animal Practice, 41(5), 869–888.

By: C. Adin* & B. Scansen*

author keywords: Upper urinary tract; Ureters; Kidneys; Endoscopy; Interventional radiology
MeSH headings : Animals; Biopsy, Needle / veterinary; Cat Diseases / surgery; Cats; Dog Diseases / surgery; Dogs; Postoperative Complications / prevention & control; Postoperative Complications / veterinary; Urologic Diseases / pathology; Urologic Diseases / surgery; Urologic Diseases / veterinary; Urologic Surgical Procedures / adverse effects; Urologic Surgical Procedures / veterinary
TL;DR: Complications pertaining to surgery of the kidney and ureter in companion animals are discussed, using experimental and clinical data to guide the detection and avoidance of these complications. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2011 journal article

Preface: Surgical Complications

Veterinary Clinics of North America: Small Animal Practice, 41(5), xi-xii.

By: C. Adin*

MeSH headings : Animals; Humans; North America; Postoperative Complications / prevention & control; Postoperative Complications / veterinary; Surgery, Veterinary / standards
TL;DR: “Although today the authors are spared the horror of operations without anesthesia and the misery of mortality from uncontrolled hospital gangrene, they still find there are other problems that they have to face with steadfastness, self-control and intensity of purpose if they are to achieve that very great contentment and happiness in successful treatment of their patients. (via Semantic Scholar)
Source: Crossref
Added: December 29, 2020

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