Claire Amanda Wiley

College of Veterinary Medicine

Works (2)

Updated: July 9th, 2023 21:16

2023 journal article

Whole exome sequencing analysis of canine urothelial carcinomas without BRAF V595E mutation: Short in-frame deletions in BRAF and MAP2K1 suggest alternative mechanisms for MAPK pathway disruption

PLOS GENETICS, 19(4).

By: R. Thomas n, C. Wiley n, E. Droste n, J. Robertson n , B. Inman * & M. Breen n

Ed(s): T. Leeb

MeSH headings : Dogs; Animals; Humans; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / veterinary; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / veterinary; Proto-Oncogene Proteins B-raf / genetics; Exome Sequencing; Mutation; MAP Kinase Kinase 1 / genetics
TL;DR: It is suggested that short in-frame deletions within BRAF exon 12 and MAP2K1 exons 2 and 3 in UDV595E cases are alternative MAPK-pathway activating events that may have significant therapeutic implications for selecting first-line treatment for canine UC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 15, 2023

2019 journal article

Novel Noninvasive Diagnostics

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 49(5), 781-+.

By: C. Wiley n, C. Wise n & M. Breen n

author keywords: Canine; Cancer; Liquid biopsy; Bladder; Prostate; BRAF; Lymphoma
MeSH headings : Animals; Carcinoma, Transitional Cell / diagnosis; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs; Early Detection of Cancer / methods; Early Detection of Cancer / veterinary; Female; Humans; Leukemia / diagnosis; Leukemia / veterinary; Liquid Biopsy / methods; Liquid Biopsy / veterinary; Lymphoma / diagnosis; Lymphoma / drug therapy; Lymphoma / veterinary; Male; Molecular Targeted Therapy / veterinary; Mutation; Neoplasms / diagnosis; Neoplasms / drug therapy; Neoplasms / genetics; Neoplasms / veterinary; Urethral Neoplasms / diagnosis; Urethral Neoplasms / genetics; Urethral Neoplasms / veterinary; Urinary Bladder Neoplasms / veterinary
TL;DR: Noninvasive/minimally invasive techniques have been described in veterinary medicine that could be referred to as liquid biopsy, which offer new opportunities for improving cancer screening, diagnosis, and monitoring the impact of therapy on the patients over time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 16, 2019

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.