Works (1)
Updated: July 5th, 2023 15:39
2016 journal article
Development of a human physiologically based pharmacokinetic (PBPK) model for dermal permeability for lindane
TOXICOLOGY LETTERS, 245, 106–109.
author keywords: PBPK; Lindane; Dermal permeability
MeSH headings : Algorithms; Diffusion; Hexachlorocyclohexane / pharmacokinetics; Humans; Insecticides / pharmacokinetics; Lipid Metabolism; Models, Biological; Permeability; Protein Binding; Skin / metabolism; Skin Absorption
TL;DR:
The estimation of permeability coefficients using chemical binding in combination with in vivo data demonstrates the advantages of combining physiochemical properties with a PBPK model to predict dermal absorption.
(via Semantic Scholar)
open access via manuscript.elsevier.com (publisher PDF)
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Added: August 6, 2018
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