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Works (11)
Updated: April 5th, 2024 00:15
2013 book
Experimental biochemistry: Theory, experiment, analysis and reporting
Dubuque, Iowa: Kendall Hunt.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Effect of sulfated polysaccharides on heat-induced structural changes in beta-lactoglobulin
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 52(12), 3975–3981.
author keywords: beta-lactoglobulin; thermal stability; heat denaturation; DSC; CD; dextran sulfate; lambda-carrageenan
MeSH headings : Carrageenan / pharmacology; Dextrans / pharmacology; Drug Stability; Hot Temperature; Lactoglobulins / chemistry; Polysaccharides / pharmacology; Protein Denaturation; Sulfates / pharmacology; Thermodynamics
TL;DR:
Assessment of changes in the denaturation thermodynamics and protein structure indicate that dextran sulfate and lambda-carrageenan can enhance the stability of beta-lactoglobulin and thereby inhibit heat denaturation and aggregation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Extraction of information on the buildup and consumption of reactive intermediates from quadruplex DNA assembly time courses
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1679(1), 59–64.
author keywords: intermediate species; quadruplex DNA assembly; time course
MeSH headings : Circular Dichroism; DNA / chemistry; Kinetics; Nucleic Acid Conformation
TL;DR:
A method was developed to detect the time course of the overall presence of intermediate species during K+-induced DNA quadruplex assembly from single-stranded d(TG4) oligonucleotides in experiments in which only the combined circular dichroisms of all species present could be measured directly.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 review
Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids
[Review of ]. BIOPOLYMERS, 56(3), 147–194.
author keywords: dissociation; assembly; quadruplex DNA structures; quadruplex RNAs; stabilization, destabilization; binding energies; thermodynamics; transformation rates; kinetics; transition-state energies and mechanisms
TL;DR:
This survey classifies factors, describes the trends and focuses on their interdependencies of quadruplex formation, and summarizes the functional conclusion drawn from each cited piece of thermodynamic or kinetic data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Phospholipid/fatty acid-induced secondary structural change in beta-lactoglobulin during heat-induced gelation
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 48(3), 605–610.
author keywords: beta-lactoglobubin; phosphatidylcholine; fatty acid; gelation; secondary structure; viscoelasticity
MeSH headings : Fatty Acids / chemistry; Gels; Hot Temperature; Humans; Lactoglobulins / chemistry; Phosphatidylcholines / chemistry; Protein Structure, Secondary
TL;DR:
Effects of phosphatidylcholine and the predominant fatty acids (FAs) in milk, butyrate, oleate, and palmitate, on secondary structural changes in beta-lactoglobulin (beta-LG) during heat-induced gelation were analyzed on the basis of circular dichroism (CD) spectra.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1999 patent
Antibodies that selectively bind quadruplex nucleic acids
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Folding of pyrimidine-enriched RNA fragments from the vicinity of the internal ribosomal entry site of Hepatitis A virus
NUCLEIC ACIDS RESEARCH, 27(2), 665–673.
MeSH headings : Base Pairing; Base Sequence; Circular Dichroism; Hepatovirus / genetics; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Potentiometry; Protein Biosynthesis; Pyrimidine Nucleotides / chemistry; RNA, Viral / chemistry; Ribosomes / metabolism
TL;DR:
A series of possible models in which chain folding draws the strand termini closer together, possibly serving to pull the attached WC hairpin domains together and providing a functional advantage by nucleating reversible formation of a more viable RNA substrate are presented.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Construction and characterization of a quadruplex DNA selective single-chain autoantibody from a viable motheaten mouse hybridoma with homology to telomeric DNA binding proteins
BIOCHEMISTRY, 37(46), 16338–16348.
MeSH headings : Amino Acid Sequence; Animals; Antibodies, Antinuclear / chemistry; Antibodies, Antinuclear / genetics; Antibodies, Antinuclear / isolation & purification; Base Sequence; Cloning, Molecular; DNA / immunology; DNA / metabolism; DNA-Binding Proteins / chemistry; G-Quadruplexes; Hybridomas / chemistry; Immunoglobulin Variable Region / chemistry; Immunoglobulin Variable Region / genetics; Immunoglobulin Variable Region / isolation & purification; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Nucleic Acid Conformation; Protein Engineering / methods; Recombinant Fusion Proteins / chemical synthesis; Recombinant Fusion Proteins / isolation & purification; Sequence Homology, Amino Acid; Single-Chain Antibodies; Telomere / metabolism
TL;DR:
The presence of this antibody in the autoimmune repertoire suggests a possible linkage between autoimmunity, telomeric DNA binding proteins, and aging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 review
Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune "viable motheaten" mice
[Review of ]. BIOCHEMISTRY, 37(46), 16325–16337.
MeSH headings : Animals; Antibodies, Antinuclear / chemistry; Antibodies, Antinuclear / isolation & purification; Antibodies, Monoclonal / chemistry; Antibodies, Monoclonal / isolation & purification; Antibody Affinity / genetics; Antibody Specificity / genetics; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Base Sequence; Binding Sites, Antibody / genetics; DNA / chemistry; DNA / immunology; DNA / metabolism; G-Quadruplexes; Hybridomas; Immunoglobulin G / metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes / immunology; Nucleic Acid Heteroduplexes / metabolism; Protein Conformation; Regression Analysis
TL;DR:
In vitro radioimmunofilter binding experiments demonstrated that purified anti-DNA quadruplex antibodies from anti-quadruplex antibody-producing tissue culture supernatants have at least 10-fold higher affinity for quadruplexes than for triplex and duplex DNA structures of similar base composition and length.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1997 journal article
Allosteric interactions between DNA strands and monovalent cations in DNA quadruplex assembly: Thermodynamic evidence for three linked association pathways
BIOCHEMISTRY, 36(49), 15428–15450.
MeSH headings : Allosteric Regulation; Cations, Monovalent; Circular Dichroism; DNA / chemistry; Kinetics; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation; Thermodynamics
TL;DR:
It is proposed that, in addition to the more conventional assembly mechanisms involving duplex dimerization and stepwise strand addition, quadruplex formation can also proceed by triplex-triplex disproportionation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1997 patent
Occupancy sensor and method of operating same
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
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