Clarke E. Atkins

Works (101)

Updated: August 16th, 2024 13:38

2023 article

Efficacy of a mitral regurgitation severity index to predict long-term outcome in dogs with myxomatous mitral valve disease

Vereb, M., Atkins, C. E., Adin, D., Blondel, T., Coffman, M., Lee, S., … Ward, J. L. (2023, November 1). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: M. Vereb*, C. Atkins n, D. Adin*, T. Blondel, M. Coffman, S. Lee, E. Guillot, J. Ward *

author keywords: congestive heart failure; echocardiography; prognosis; thoracic radiographs; vertebral heart size; vertebral left atrial size
TL;DR: MRSI was predictive of outcome (onset of CHF and all‐cause death) in MMVD Stage B2, demonstrating utility as a useful prognostic tool. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 20, 2023

2023 journal article

Evaluation of Renin-Angiotensin-Aldosterone System Components and Enzymes in Systemically Hypertensive Cats Receiving Amlodipine

ANIMALS, 13(22).

By: D. Adin*, C. Atkins n, O. Domenig, C. Glahn, T. Defrancesco n  & K. Meurs n 

author keywords: feline; blood pressure; kidney
TL;DR: The findings suggest that the use of concurrent RAAS-suppressant therapy, specifically aldosterone antagonism, in amlodipine-treated SHT cats with chronic kidney disease might be indicated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 18, 2023

2022 article

Prevalence of aldosterone breakthrough in dogs receiving renin-angiotensin system inhibitors for proteinuric chronic kidney disease

Ames, M. K., Vaden, S. L., Atkins, C. E., Palerme, J.-S., Langston, C. E., Grauer, G. F., … Webb, T. (2022, November 9). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: M. Ames*, S. Vaden n, C. Atkins n, J. Palerme*, C. Langston *, G. Grauer*, S. Shropshire *, C. Bove*, T. Webb *

author keywords: mineralocorticoid receptor antagonists; nephrology; renin-angiotensin-aldosterone system; urine aldosterone to creatinine ratio
MeSH headings : Dogs; Animals; Aldosterone; Renin-Angiotensin System / physiology; Creatinine / urine; Prospective Studies; Prevalence; Antihypertensive Agents / therapeutic use; Proteinuria / drug therapy; Proteinuria / veterinary; Renal Insufficiency, Chronic / drug therapy; Renal Insufficiency, Chronic / veterinary; Dog Diseases / drug therapy
TL;DR: Whether ABT occurs in dogs with CKDP and if it is associated with decreased efficacy in proteinuria reduction during RAS inhibitor treatment is investigated and its relationship with outcomes is evaluated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 21, 2022

2021 journal article

Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy

ANIMAL GENETICS, 52(4), 542–544.

By: . K. O'Donnell, D. Adin n, C. Atkins n, T. DeFrancesco n , B. Keene n, S. Tou n, K. Meurs n 

author keywords: cardiomyopathy; feline; genetic; HCM; mutation
MeSH headings : Animals; Cardiomyopathy, Hypertrophic / genetics; Cardiomyopathy, Hypertrophic / veterinary; Carrier Proteins / genetics; Carrier Proteins / metabolism; Cat Diseases / genetics; Cat Diseases / metabolism; Cats; Female; Genetic Variation; Male; Myosin Heavy Chains / genetics; Myosin Heavy Chains / metabolism
TL;DR: The lack of these MYBPC3 and MYH7 variants in this feline HCM population indicates that the clinical utility of genetic testing for these variants may be isolated to the two cat breeds in which these variants have been identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 17, 2021

2021 article

Clinical efficacy of a benazepril and spironolactone combination in dogs with congestive heart failure due to myxomatous mitral valve disease: The BEnazepril Spironolactone STudy (BESST)

Coffman, M., Guillot, E., Blondel, T., Garelli-Paar, C., Feng, S., Heartsill, S., & Atkins, C. E. (2021, May 24). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: M. Coffman, E. Guillot *, T. Blondel, C. Garelli-Paar*, S. Feng, S. Heartsill, C. Atkins n

author keywords: ACE inhibitor; aldosterone breakthrough; mitral regurgitation; MRA; RAAS
MeSH headings : Animals; Benzazepines; Dog Diseases / drug therapy; Dogs; Heart Failure / drug therapy; Heart Failure / veterinary; Mitral Valve; Spironolactone / therapeutic use; Treatment Outcome
TL;DR: The combination of S+BNZ is effective, safe, and superior to benazepril alone, when used with furosemide for the management of mild, moderate or severe CHF caused by MMVD in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021

2021 journal article

Effect of spironolactone and benazepril on furosemide-induced diuresis and renin-angiotensin-aldosterone system activation in normal dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(3), 1245–1254.

By: D. Adin*, C. Atkins n, G. Wallace * & A. Klein n

author keywords: aldosterone antagonist; angiotensin‐ converting enzyme inhibitor; continuous rate infusion; diuretic resistance; neurohormone; urine production
MeSH headings : Aldosterone; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Benzazepines; Diuresis; Diuretics / pharmacology; Dogs; Furosemide / pharmacology; Male; Renin-Angiotensin System; Spironolactone / pharmacology
TL;DR: The neurohormonal profile during FCRI supports RAAS mediation of diuretic braking in this model, and delayed changes in sCr and serum sodium concentration and incomplete recovery of hydration indicators caused by furosemide hold implications for clinical patients. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: April 5, 2021

2021 personal communication

Letter to the editor regarding "Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial"

Atkins, C., Keene, B., DeFrancesco, T. C., Tou, S., Chetboul, V., Cote, E., … Stepien, R. L. (2021, March).

By: C. Atkins n, B. Keene n, T. DeFrancesco n , S. Tou n, V. Chetboul *, E. Cote *, S. Ettinger, P. Fox * ...

MeSH headings : Animals; Dogs; Furosemide / therapeutic use; Mitral Valve; Pyridazines / therapeutic use; Ramipril / therapeutic use
TL;DR: The VALVE trial did not assess the efficacy of RAAS suppression using biomarkers, and the question of whether ramipril adequately or optimally suppressed RAAS, while failing to improve survival in the face of these diuretic dosages, remains unanswered. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2021 journal article

Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 259(12), 1428–1432.

By: D. DeProspero n, . Kerry A. O'Donnell n, T. DeFrancesco n , B. Keene n, S. Tou n, D. Adin n, C. Atkins n, K. Meurs n 

MeSH headings : Animals; Dog Diseases / epidemiology; Dogs; Heart Valve Diseases / veterinary; Humans; Mitral Valve; Mitral Valve Prolapse / epidemiology; Mitral Valve Prolapse / veterinary; Prospective Studies
TL;DR: Features of the disease among Miniature Schnauzers and Yorkshire Terriers were similar, but there were also a few discernable differences between these 2 breeds and from historical findings for dogs with MMVD of other breeds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 21, 2022

2020 journal article

Atenolol in cats with subclinical hypertrophic cardiomyopathy: a double-blind, placebo-controlled, randomized clinical trial of effect on quality of life, activity, and cardiac biomarkers

JOURNAL OF VETERINARY CARDIOLOGY, 30, 77–91.

By: A. Coleman  n, T. DeFrancesco n , E. Griffiths n, B. Lascelles  n, D. Kleisch n, C. Atkins n, B. Keene n

author keywords: Feline; Beta-btocker; Accelerometry
MeSH headings : Administration, Oral; Animals; Anti-Arrhythmia Agents / administration & dosage; Anti-Arrhythmia Agents / therapeutic use; Atenolol / administration & dosage; Atenolol / therapeutic use; Biomarkers / blood; Cardiomyopathy, Hypertrophic / drug therapy; Cardiomyopathy, Hypertrophic / veterinary; Cat Diseases / blood; Cat Diseases / drug therapy; Cats; Double-Blind Method; Female; Male; Quality of Life; Treatment Outcome
TL;DR: This study failed to identify an effect of subclinical HCM on owner-assessed QOL or activity or a treatment effect of atenolol on these variables at the dosage evaluated, and these findings do not support a treatment benefit of atanolol for the goal of symptom reduction in cats with sub clinical HCM. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 21, 2020

2020 journal article

Correction of serum chloride concentration in dogs with congestive heart failure

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(1), 51–57.

By: D. Adin*, C. Atkins n, L. Londono * & B. Del Nero*

author keywords: antidiuretic hormone; hypochloremia; sodium
MeSH headings : Animals; Chlorides; Diuretics / therapeutic use; Dog Diseases / drug therapy; Dogs; Heart Failure / drug therapy; Heart Failure / veterinary; Retrospective Studies; Sodium
TL;DR: Serum [Cl- ] increased after mathematical correction in Stage D CHF dogs but not in Stage C and NO-CHF dogs, and hypochloremia persisted, consistent with concurrent loop diuretic effects on electrolytes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: January 4, 2021

2020 journal article

Non-Arsenical heartworm adulticidal therapy using topical moxidectin-imidacloprid and doxycycline: A prospective case series

VETERINARY PARASITOLOGY, 282.

By: M. Ames*, P. VanVranken*, C. Evans* & C. Atkins n

author keywords: Dirofilaria immitis; Dog; Moxidectin; Doxycycline; Melarsomine dihydrochloride; Slow-kill
MeSH headings : Animals; Antinematodal Agents / therapeutic use; Dirofilaria immitis / drug effects; Dirofilariasis / drug therapy; Dog Diseases / drug therapy; Dogs; Doxycycline / therapeutic use; Drug Therapy, Combination / veterinary; Female; Macrolides / therapeutic use; Male; Neonicotinoids / therapeutic use; Nitro Compounds / therapeutic use; Prospective Studies
TL;DR: The MOXY protocol was tolerated and 96 % (21/22) of dogs converted to NAD, though 2 dogs required greater than 1 year to achieve this result, and exercise restriction should be considered when using a nonarsenical protocol. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 21, 2020

2020 journal article

Renin-angiotensin aldosterone profile before and after angiotensin-converting enzyme-inhibitor administration in dogs with angiotensin-converting enzyme gene polymorphism

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 600–606.

By: D. Adin*, C. Atkins n, O. Domenig, T. DeFrancesco n , B. Keene n, S. Tou n, J. Stern* , K. Meurs n 

author keywords: ACE-inhibitor; enalapril; genotype; pharmacogenetic; pharmacogenomic
MeSH headings : Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Genetic Predisposition to Disease; Genotype; Humans; Mitral Valve Prolapse / enzymology; Mitral Valve Prolapse / genetics; Peptidyl-Dipeptidase A / genetics; Peptidyl-Dipeptidase A / metabolism; Polymorphism, Genetic; Renin-Angiotensin System / physiology; Retrospective Studies
TL;DR: The results support the use of aldosterone receptor antagonists with ACE‐inhibitors when RAAS inhibition is indicated for dogs, especially those positive for the ACE gene polymorphism, which did not alter baseline RAAS activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 16, 2020

2020 journal article

Treatment of dogs with severe heartworm disease

VETERINARY PARASITOLOGY, 283.

By: M. Ames* & C. Atkins n

author keywords: Dirofilaria immitis; Pneumonitis; Hypersensitivity reaction; Pulmonary hypertension; Pulmonary thromboembolism; Heart failure; Caval syndrome
MeSH headings : Animals; Dirofilariasis / complications; Dirofilariasis / diagnosis; Dirofilariasis / drug therapy; Dirofilariasis / parasitology; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Drug Hypersensitivity / etiology; Drug Hypersensitivity / veterinary; Filaricides / therapeutic use
TL;DR: Complications occurring with heartworm infection and during its treatment most often directly reflect the pulmonary vascular and parenchymal injury inflicted by Dirofilaria immitis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 21, 2020

2019 journal article

ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(3), 1127–1140.

By: B. Keene n, C. Atkins n, J. Bonagura n , P. Fox *, J. Haggstrom *, V. Fuentes *, M. Oyama *, J. Rush * ...

Contributors: B. Keene n, C. Atkins n, J. Bonagura n , P. Fox *, J. Häggström *, V. Fuentes *, M. Oyama *, J. Rush *, R. Stepien *, M. Uechi

author keywords: canine; congestive heart failure; evidence-based treatment; mitral
MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Heart Failure / diagnosis; Heart Failure / therapy; Heart Failure / veterinary; Hypertension, Pulmonary / diagnosis; Hypertension, Pulmonary / therapy; Hypertension, Pulmonary / veterinary; Mitral Valve Insufficiency / diagnosis; Mitral Valve Insufficiency / therapy; Mitral Valve Insufficiency / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 1, 2019

2019 review

The renin-angiotensin-aldosterone system and its suppression

[Review of ]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(2), 363–382.

By: M. Ames*, C. Atkins n & B. Pitt *

author keywords: angiotensin converting enzyme inhibitor; angiotensin receptor blocker; chronic kidney disease; heart failure; mineralocorticoid receptor blocker; proteinuric kidney disease; systemic hypertension
MeSH headings : Aldosterone / metabolism; Angiotensin II / metabolism; Angiotensin Receptor Antagonists / therapeutic use; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Dog Diseases / drug therapy; Dog Diseases / physiopathology; Dogs; Heart Failure / veterinary; Hypertension / veterinary; Kidney Diseases / veterinary; Mineralocorticoid Receptor Antagonists / therapeutic use; Renin-Angiotensin System / drug effects; Renin-Angiotensin System / physiology
TL;DR: This review focuses on updates in the understanding of the RAAS and the pathophysiology of AngII and aldosterone excess, reviewing what is known about its suppression in cardiovascular and renal diseases, especially in the cat and dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 22, 2019

2018 journal article

Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type

JOURNAL OF VETERINARY CARDIOLOGY, 21, 1–9.

By: D. Adin n, T. DeFrancesco n , B. Keene n, S. Tou n, K. Meurs n , C. Atkins n, B. Aona n, K. Kurtz n ...

author keywords: Nutritional; Heart failure; Dog; Taurine
MeSH headings : Animals; Cardiomyopathy, Dilated / diagnostic imaging; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / veterinary; Diet / adverse effects; Diet / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Echocardiography / veterinary; Edible Grain / adverse effects; Female; Male; Phenotype
TL;DR: Dietary-associated DCM occurs with some GF diets and can improve with nutritional management, including diet change, and the role of taurine supplementation, even without deficiency, is uncertain. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 2, 2019

2018 journal article

Myxomatous mitral valve disease in the miniature poodle: A retrospective study

VETERINARY JOURNAL, 244, 94–97.

By: K. Meurs n , D. Adin n, . K. O'Donnell, B. Keene n, C. Atkins n, T. DeFrancesco n , S. Tou n

author keywords: Canine; Genetic; Miniature poodle; Mitral valve; Myxomatous valve
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / epidemiology; Dog Diseases / genetics; Dogs; Female; Male; Mitral Valve Prolapse / diagnostic imaging; Mitral Valve Prolapse / epidemiology; Mitral Valve Prolapse / genetics; Mitral Valve Prolapse / veterinary; North Carolina / epidemiology; Pedigree; Records; Retrospective Studies; Severity of Illness Index
TL;DR: In the miniature poodles reported here, MMVD appears to be a fairly late onset disease and often is a mild phenotype. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 2, 2019

2018 journal article

Pharmacodynamic assessment of diuretic efficacy and braking in a furosemide continuous infusion model

JOURNAL OF VETERINARY CARDIOLOGY, 20(2), 92–101.

By: D. Adin n, C. Atkins n & M. Papich n 

author keywords: Lasix; Urine; Natriuresis; Aldosterone
MeSH headings : Aldosterone / urine; Animals; Diuretics / administration & dosage; Diuretics / blood; Diuretics / pharmacology; Diuretics / urine; Dogs; Electrolytes / urine; Furosemide / administration & dosage; Furosemide / blood; Furosemide / pharmacology; Furosemide / urine; Infusions, Intravenous; Male; Renin-Angiotensin System / drug effects
TL;DR: The decrease in uNa:uK over time during the infusion is consistent with mineralocorticoid modification of urinary electrolyte excretion, supporting renin-angiotensin-aldosterone activation as a cause of diuretic braking in this model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Aldosterone breakthrough in dogs with naturally occurring myxomatous mitral valve disease

JOURNAL OF VETERINARY CARDIOLOGY, 19(3), 218–227.

By: M. Ames n, C. Atkins n, A. Eriksson  n & A. Hess *

author keywords: Angiotensin converting enzyme inhibitor; Mineralocorticoid receptor blacker; Heart failure; Renin angiotensin aldosterone system
MeSH headings : Aldosterone / urine; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Creatinine / urine; Dog Diseases / drug therapy; Dogs; Female; Furosemide; Heart Failure; Heart Valve Diseases / drug therapy; Heart Valve Diseases / veterinary; Humans; Male; Mitral Valve; Renin-Angiotensin System / drug effects; Renin-Angiotensin System / physiology
TL;DR: It appears that incomplete RAAS blockade is common in dogs with MMVD receiving an ACEI, and the proven existence of ABT in dogs offers the potential to improve the prognosis for MMVD with the addition of a mineralocorticoid receptor blocker to current therapeutic regimens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Angiotensin-converting enzyme activity and inhibition in dogs with cardiac disease and an angiotensin-converting enzyme polymorphism

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 18(4).

By: K. Meurs n , J. Stern n , C. Atkins n, D. Adin n, B. Aona n, J. Condit n, T. DeFrancesco n , Y. Reina-Doreste n ...

author keywords: Polymorphism; canine; angiotensin-converting enzyme; enalapril
MeSH headings : Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Breeding; Dogs; Genotype; Heart Diseases / drug therapy; Heart Diseases / enzymology; Heart Diseases / genetics; Peptidyl-Dipeptidase A / genetics; Polymorphism, Genetic
TL;DR: It is possible that the genetic status and ACE activity of dogs may impact the response of dogs with this variant to an ACE inhibitor, and an ACE polymorphism is associated with lower levels of ACE activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

ECG of the month

Journal of the American Veterinary Medical Association, 250(2), 166–168.

By: J. Mathews, A. Coleman & C. Atkins*

MeSH headings : Animals; Arrhythmias, Cardiac / etiology; Arrhythmias, Cardiac / veterinary; Dog Diseases / therapy; Dogs; Electrocardiography / veterinary; Female; Pacemaker, Artificial / veterinary
Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration

VETERINARY JOURNAL, 232, 16–19.

By: K. Meurs n , S. Friedenberg *, B. Williams n, B. Keene n, C. Atkins n, D. Adin n, B. Aona n, T. DeFrancesco n  ...

author keywords: Canine; Cavalier King Charles spaniel; Dachshund; Genetic; Mitral valve; Myxomatous valve
MeSH headings : Animals; DNA / blood; Dog Diseases / genetics; Dogs; Heart Valve Diseases / genetics; Heart Valve Diseases / veterinary; Humans; Mitral Valve; Mitral Valve Prolapse / genetics; Mutation; Species Specificity; Whole Genome Sequencing / veterinary
TL;DR: Although mitral valve disease in the CKCS and Dachshund is a familial disease, it was hypothesized that a genetic mutation associated with the development of the human form of MMVD was associated withthe development of canine MMVD and this work identified genetic cause in the genes responsible for the human disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Evaluation of subacute change in RAAS activity (as indicated by urinary aldosterone: creatinine, after pharmacologic provocation) and the response to ACE inhibition

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 17(1).

By: M. Ames *, C. Atkins n, A. Lantis & J. Brunnen*

author keywords: Aldosterone breakthrough; RAAS activation; angiotensin-converting enzyme inhibitors; mineralocorticoid receptor blockers; heart failure
MeSH headings : Aldosterone / urine; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Creatinine / urine; Dogs; Female; Male; Peptidyl-Dipeptidase A / blood; Renin-Angiotensin System / drug effects
TL;DR: Increases in UAldo:C, despite ACEI administration, is evidence of IRB in this subacute model of experimental RAAS activation and suppression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Furosemide continuous rate infusion diluted with 5% dextrose in water or hypertonic saline in normal adult dogs: a pilot study

JOURNAL OF VETERINARY CARDIOLOGY, 19(1), 44–56.

By: D. Adin n, C. Atkins n, M. Papich n , T. DeFrancesco n , E. Griffiths n, M. Penteado*, K. Kurtz n, A. Klein n

author keywords: Lasix; Diuretic; Sodium; Salt
MeSH headings : Animals; Cross-Over Studies; Diuretics / administration & dosage; Diuretics / adverse effects; Diuretics / pharmacokinetics; Dogs; Furosemide / administration & dosage; Furosemide / adverse effects; Furosemide / pharmacokinetics; Glucose / administration & dosage; Infusions, Intravenous / veterinary; Male; Pilot Projects; Saline Solution, Hypertonic / administration & dosage; Single-Blind Method; Water
TL;DR: Diuresis was similar for both furosemide CRI methods; however, the H-SAL method induced less renin-angiotensin-aldosterone system activation than the DEX method, suggesting that dilution of a furo Semine CRI with 2.4% hypertonic saline may be well tolerated in heart failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Outcome and survival in canine sick sinus syndrome and sinus node dysfunction: 93 cases (2002-2014)

JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 199–212.

By: J. Ward n, T. DeFrancesco n , S. Tou n, C. Atkins n, E. Griffith n & B. Keene n

author keywords: Dog; Arrhythmia; Bradycardia; Sinus arrest; Pacemaker
MeSH headings : Animals; Dog Diseases / mortality; Dogs; Prognosis; Sick Sinus Syndrome / mortality; Sick Sinus Syndrome / veterinary; Sinoatrial Node / physiopathology; Survival Analysis; Treatment Outcome
TL;DR: Sinus node dysfunction and SSS represent a spectrum of sinoatrial node disease, which for some dogs may also involve a component of autonomic dysfunction, and medical management is often useful, particularly in atropine responsive dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Cardiovascular-renal axis disorders in the domestic dog and cat: a veterinary consensus statement

JOURNAL OF SMALL ANIMAL PRACTICE, 56(9), 537–552.

By: J. Pouchelon*, C. Atkins n, C. Bussadori, M. Oyama *, S. Vaden n, J. Bonagura* , V. Chetboul *, L. Cowgill * ...

Contributors: J. Pouchelon*, C. Atkins n, C. Bussadori, M. Oyama *, S. Vaden n, J. Bonagura* , V. Chetboul *, L. Cowgill * ...

MeSH headings : Animals; Cardio-Renal Syndrome / diagnosis; Cardio-Renal Syndrome / epidemiology; Cardio-Renal Syndrome / therapy; Cardio-Renal Syndrome / veterinary; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cat Diseases / therapy; Cats; Consensus; Delphi Technique; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / therapy; Dogs; Practice Guidelines as Topic; Veterinary Medicine
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Complication Rates Associated with Transvenous Pacemaker Implantation in Dogs with High-Grade Atrioventricular Block Performed During versus After Normal Business Hours

JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(1), 157–163.

By: J. Ward n, T. DeFrancesco n , S. Tou n, C. Atkins n, E. Griffith n & B. Keene n

author keywords: Canine; Heart block; Transvenous
MeSH headings : Animals; Atrioventricular Block / therapy; Atrioventricular Block / veterinary; Cardiovascular Surgical Procedures / adverse effects; Cardiovascular Surgical Procedures / veterinary; Dog Diseases / therapy; Dogs; Pacemaker, Artificial / veterinary; Postoperative Complications / veterinary; Retrospective Studies; Treatment Outcome
TL;DR: AH transvenous pacemaker placement is associated with a higher rate of major complications (especially infections) compared to BH placement, and this difference may be because of a variety of human factor differences AH versus BH. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Effects of high doses of enalapril and benazepril on the pharmacologically activated renin-angiotensin-aldosterone system in clinically normal dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 76(12), 1041–1050.

By: M. Ames*, C. Atkins*, S. Lee, A. Lantis* & J. zumBrunnen

MeSH headings : Aldosterone / blood; Aldosterone / urine; Angiotensin-Converting Enzyme Inhibitors / administration & dosage; Animals; Benzazepines / administration & dosage; Blood Pressure / drug effects; Body Weight / drug effects; Dogs / physiology; Enalapril / administration & dosage; Female; Furosemide / administration & dosage; Heart Rate / drug effects; Male; Peptidyl-Dipeptidase A / blood; Renin-Angiotensin System / drug effects; Time Factors
TL;DR: Administration of high doses of enalapril and benazepril significantly inhibited ACE activity, yet did not prevent increases in mean urine and serum aldosterone concentrations resulting from furosemide activation of RAAS, suggesting that ald testosterone breakthrough from ACE inhibition was a dose-independent effect of ACE inhibitors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

The effect of enalapril on furosemide-activated renin-angiotensin-aldosterone system in healthy dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 38(5), 513–517.

By: A. Lantis*, M. Ames n, S. Werre * & C. Atkins n

TL;DR: It appears that failure to suppress aldosterone suppression with furosemide stimulation may be a drug class effect, and the discrepancy between the current data and the documented benefits of enalapril likely reflects the efficacy of this ACE inhibitor in suppressing tissue RAAS, variable population responsiveness to ACE-inhibition, and/or providing additional survival benefits, possibly through as yet unknown mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Aldosterone breakthrough with benazepril in furosemide-activated renin-angiotensin-aldosterone system in normal dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 38(1), 65–73.

By: A. Lantis n, M. Ames n, C. Atkins n, T. Defrancesco n , B. Keene n & S. Werre  n

MeSH headings : Aldosterone / metabolism; Aldosterone / urine; Angiotensin-Converting Enzyme Inhibitors / administration & dosage; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Benzazepines / administration & dosage; Benzazepines / pharmacology; Diuretics / administration & dosage; Diuretics / pharmacology; Dogs / physiology; Dogs / urine; Drug Therapy, Combination; Furosemide / administration & dosage; Furosemide / pharmacology; Peptidyl-Dipeptidase A; Renin-Angiotensin System / drug effects; Renin-Angiotensin System / physiology
TL;DR: Benazepril decreased plasma ACE activity but did not prevent furosemide-induced RAAS activation, indicating aldosterone breakthrough (escape), particularly noteworthy in that breakthrough is observed at the time of initiation of RAAS suppression, as opposed to developing after months of therapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Case-control study of the effects of pimobendan on survival time in cats with hypertrophic cardiomyopathy and congestive heart failure

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 245(5), 534–539.

By: Y. Reina-Doreste n, J. Stern* , B. Keene n, S. Tou n, C. Atkins n, T. DeFrancesco n , M. Ames n, T. Hodge n, K. Meurs n 

MeSH headings : Animals; Cardiomyopathy, Hypertrophic / drug therapy; Cardiomyopathy, Hypertrophic / mortality; Cardiomyopathy, Hypertrophic / veterinary; Cardiotonic Agents / therapeutic use; Case-Control Studies; Cat Diseases / drug therapy; Cat Diseases / mortality; Cats; Female; Heart Failure / drug therapy; Heart Failure / mortality; Heart Failure / veterinary; Male; Pyridazines / therapeutic use; Retrospective Studies
TL;DR: The addition of pimobendan to traditional treatment for CHF may provide a substantial clinical benefit in survival time for HCM-affected cats with CHF and possibly HOCM- affected cats withCHF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Heartworm 'lack of effectiveness' claims in the Mississippi delta: Computerized analysis of owner compliance-2004-2011

VETERINARY PARASITOLOGY, 206(1-2), 106–113.

By: C. Atkins n, M. Murray, L. Olavessen, K. Burton, J. Marshall & C. Brooks

author keywords: Dirofilaria immitis; Efficacy; Heartworm preventive; Macrocyclic lactone
MeSH headings : Animals; Dirofilaria immitis; Dirofilariasis / prevention & control; Dog Diseases / prevention & control; Dogs; Electronic Data Processing; Filaricides / administration & dosage; Medication Adherence / statistics & numerical data; Retrospective Studies; Southeastern United States; Tennessee; Treatment Outcome
TL;DR: In most cases, there was at least one reason that a dog did not receive sufficient heartworm preventive product, placing the dog at risk of developing an infection with mature heartworms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Recovery of normal esophageal function in a kitten with diffuse megaesophagus and an occult lower esophageal stricture

JOURNAL OF FELINE MEDICINE AND SURGERY, 17(6), 557–561.

By: J. Schneider n, M. Ames n, M. DiCicco  n, M. Savage n, C. Atkins n, M. Wood n, J. Gookin n 

MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / therapy; Catheterization / veterinary; Cats; Endoscopy / veterinary; Esophageal Achalasia / complications; Esophageal Achalasia / veterinary; Esophageal Stenosis / complications; Esophageal Stenosis / veterinary; Male; Recovery of Function
TL;DR: Management of kittens with radiographic findings suggestive of congenital megaesophagus by means of gastrostomy tube feeding may be associated with a return of normal esophageal motility and widening of the esophagal stricture, and facilitate subsequent success of interventional dilation of the EsophageAL stricture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Association of Dilated Cardiomyopathy with the Striatin Mutation Genotype in Boxer Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1437–1440.

By: K. Meurs n , J. Stern n , D. Sisson*, M. Kittleson *, S. Cunningham *, M. Ames n, C. Atkins n, T. DeFrancesco n  ...

author keywords: Boxer; Dilated cardiomyopathy; Mutation; Striatin
MeSH headings : Animals; Arrhythmogenic Right Ventricular Dysplasia / genetics; Arrhythmogenic Right Ventricular Dysplasia / physiopathology; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / physiopathology; Cardiomyopathy, Dilated / veterinary; Case-Control Studies; Confidence Intervals; DNA / chemistry; DNA / genetics; Dog Diseases / genetics; Dog Diseases / physiopathology; Dogs; Echocardiography / veterinary; Female; Genotype; Male; Membrane Proteins / genetics; Polymerase Chain Reaction / veterinary; Sequence Deletion / genetics
TL;DR: This study demonstrates an association between DCM in the Boxer dog and the striatin mutation, particularly with the homozygous genotype, and suggests that there is at least 1 other cause of DCm in the boxer dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Effect of furosemide and high-dosage pimobendan administration on the renin-angiotensin-aldosterone system in dogs

American Journal of Veterinary Research, 74(8), 1084–1090.

By: M. Ames n, C. Atkins*, A. Lantis* & S. Were

MeSH headings : Animals; Cardiotonic Agents / pharmacology; Diuretics / pharmacology; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furosemide / pharmacology; Male; Pyridazines / pharmacology; Renin-Angiotensin System / drug effects; Renin-Angiotensin System / physiology
TL;DR: High-dosage pimobendan administration neither substantially suppressed nor potentiated the RAAS when administered with furosemide in healthy dogs, and this effect was significant only for dogs that received both drugs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Safety of Spironolactone in Dogs with Chronic Heart Failure because of Degenerative Valvular Disease: A Population-Based, Longitudinal Study

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(5), 1083–1091.

By: H. Lefebvre*, E. Ollivier, C. Atkins n, B. Combes, D. Concordet *, V. Kaltsatos, L. Baduel

author keywords: Aldosterone; Potassium; Renal function; Reference interval
MeSH headings : Angiotensin-Converting Enzyme Inhibitors / administration & dosage; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Carnitine / administration & dosage; Carnitine / therapeutic use; Digoxin / administration & dosage; Digoxin / therapeutic use; Diuretics / adverse effects; Diuretics / therapeutic use; Dog Diseases / drug therapy; Dogs; Furosemide / administration & dosage; Furosemide / therapeutic use; Heart Failure / drug therapy; Heart Failure / etiology; Heart Failure / veterinary; Heart Valve Diseases / complications; Heart Valve Diseases / veterinary; Longitudinal Studies; Spironolactone / adverse effects; Spironolactone / therapeutic use
TL;DR: Dogs with heart failure receiving spironolactone in addition to conventional treatment are not at a higher risk for AEs, death caused by cardiac disease, renal disease, or both, hyperkalemia, or azotemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Cardiac structure and function in female carrier's of a canine model of Duchenne muscular dystrophy

RESEARCH IN VETERINARY SCIENCE, 94(3), 610–617.

By: A. Kane n, T. DeFrancesco n , M. Boyle*, D. Malarkey *, J. Ritchey *, C. Atkins n, J. Cullen n, J. Kornegay *, B. Keene n

author keywords: Cardiomyopathy; Carrier; GRMD; Duchenne muscular dystrophy
MeSH headings : Animals; Disease Models, Animal; Dog Diseases / genetics; Dog Diseases / pathology; Dog Diseases / physiopathology; Dogs; Echocardiography / veterinary; Electrocardiography / veterinary; Electrocardiography, Ambulatory / veterinary; Female; Heart / physiopathology; Heterozygote; Muscular Dystrophy, Animal / genetics; Muscular Dystrophy, Animal / pathology; Muscular Dystrophy, Animal / physiopathology; Myocardium / pathology
TL;DR: Despite cardiac mosaic dystrophin expression and degenerative cardiac lesions, GRMD carriers at up to 3 years of age could not be distinguished statistically from normal controls by echocardiography or 24-h Holter monitoring. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Multicenter Evaluation of Plasma N-Terminal Probrain Natriuretic Peptide (NT-pro BNP) as a Biochemical Screening Test for Asymptomatic (occult) Cardiomyopathy in Cats

Journal of Veterinary Internal Medicine, 25(5), 1010–1016.

By: P. Fox, J. Rush, C. Reynolds, T. DeFrancesco , B. Keene, C. Atkins, S. Gordon, K. Schober ...

Source: NC State University Libraries
Added: August 6, 2018

2011 article

Renal effects of Dirofilaria immitis in experimentally and naturally infected cats

Atkins, C. E., Vaden, S. L., Arther, R. G., Ciszewski, D. K., Davis, W. L., Ensley, S. M., & Chopade, N. H. (2011, March 22). VETERINARY PARASITOLOGY, Vol. 176, pp. 317–323.

By: C. Atkins n, S. Vaden n, R. Arther*, D. Ciszewski*, W. Davis*, S. Ensley*, N. Chopade*

author keywords: Feline heartworm; Proteinuria; Microalbuminuria
MeSH headings : Animals; Antibodies, Helminth / blood; Antigens, Helminth / blood; Cat Diseases / parasitology; Cat Diseases / urine; Cats; Dirofilaria immitis / pathogenicity; Dirofilariasis / parasitology; Dirofilariasis / urine; Female; Larva / pathogenicity; Male; Proteinuria / parasitology; Proteinuria / urine; Proteinuria / veterinary; Risk Factors
TL;DR: It is concluded that cats infected with mature adult heartworms are at risk for developing proteinuria and that this is recognized relatively soon after infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 review

Understanding Feline Heartworm Infection Disease, Diagnosis, and Treatment

[Review of ]. TOPICS IN COMPANION ANIMAL MEDICINE, 25(4), 224–230.

By: A. Lee * & C. Atkins n

author keywords: Dirofilaria immitis; feline; heartworm-associated respiratory disease (HARD); Wolbachia; diagnosis; treatment
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / diagnostic imaging; Cat Diseases / surgery; Cats; Dirofilaria immitis / pathogenicity; Dirofilaria immitis / physiology; Dirofilariasis / diagnosis; Dirofilariasis / diagnostic imaging; Dirofilariasis / surgery; Echocardiography / veterinary; Female; Life Cycle Stages; Male; Prognosis; Pulmonary Artery / diagnostic imaging; Pulmonary Artery / pathology; Radiography, Thoracic / veterinary; Remission, Spontaneous; Risk Factors
TL;DR: It is important for veterinarians to take a proactive preventive stance because heartworm infection in cats is a multisystemic disease that has no easy cure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Acute Effect of Pimobendan and Furosemide on the Circulating Renin-Angiotensin-Aldosterone System in Healthy Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(5), 1003–1006.

By: M. Sayer n, C. Atkins n, Y. Fujii n, A. Adams n, T. DeFrancesco n  & B. Keene n

author keywords: Furosemide; Heart failure; Inodilator; Pimobendan; Renin-angiotensin-aldosterone system
MeSH headings : Aldosterone / urine; Animals; Blood Urea Nitrogen; Chlorides / blood; Cross-Over Studies; Dogs / blood; Dogs / urine; Female; Furosemide / pharmacology; Male; Phosphorus / blood; Potassium / blood; Pyridazines / pharmacology; Renin-Angiotensin System / drug effects; Sodium / blood; Sodium Potassium Chloride Symporter Inhibitors / pharmacology; Vasodilator Agents / pharmacology
TL;DR: It is suggested that furosemide therapy, with or without pimobendan, should be accompanied by RAAS suppressive therapy, and short-term administration of high-dose pimobendedan, does not activate the RAAS in healthy dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 article

Acute death in heartworm-infected cats: Unraveling the puzzle (vol 158, pg 196, 2008)

Veterinary Parasitology, Vol. 163, pp. 376–376.

By: A. Litster, C. Atkins & R. Atwell

Source: NC State University Libraries
Added: August 6, 2018

2009 article

ECG of the Month

Lantis, A. C., & Atkins, C. E. (2009, September 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 235, pp. 514–516.

By: A. Lantis n & C. Atkins*

MeSH headings : Animals; Antineoplastic Agents / adverse effects; Bundle-Branch Block / chemically induced; Bundle-Branch Block / veterinary; Dog Diseases / chemically induced; Dogs; Electrocardiography / veterinary; Female; Heart Diseases / chemically induced; Heart Diseases / veterinary; Tachycardia, Sinus / chemically induced; Tachycardia, Sinus / veterinary
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 review

Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease

[Review of ]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(6), 1142–1150.

By: C. Atkins n, J. Bonagura* , S. Ettinger*, P. Fox *, S. Gordon *, J. Haggstrom *, R. Hamlin *, B. Keene n, V. Luis-Fuentes *, R. Stepien *

Contributors: C. Atkins n, J. Bonagura* , S. Ettinger*, P. Fox *, S. Gordon *, J. Haggstrom *, R. Hamlin *, B. Keene n, V. Luis-Fuentes *, R. Stepien *

author keywords: Cardiology; Cardiovascular; Heart failure; Therapy
MeSH headings : Animals; Chronic Disease; Dog Diseases / diagnosis; Dogs; Heart Failure / therapy; Heart Failure / veterinary; Heart Valve Diseases / diagnosis; Heart Valve Diseases / therapy; Heart Valve Diseases / veterinary; Practice Guidelines as Topic
TL;DR: CVHD is the most common heart disease of dogs in many parts of the world, accounting for approximately 75% of canine cases of heart disease cases seen by veter-inary practices in North America. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Heartworm Biology, Treatment, and Control

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 39(6), 1127-+.

By: D. Bowman * & C. Atkins n

author keywords: Dirofilaria; Microfilariae; Right-heart failure; Caval syndrome; Heartworm development units
MeSH headings : Animals; Cat Diseases / drug therapy; Cat Diseases / epidemiology; Cat Diseases / prevention & control; Cats; Culicidae / parasitology; Dirofilaria immitis / physiology; Dirofilariasis / drug therapy; Dirofilariasis / epidemiology; Dirofilariasis / prevention & control; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dog Diseases / prevention & control; Dogs; Humans; Insect Vectors; United States / epidemiology
TL;DR: The article discusses the pathophysiological mechanisms behind the disease induced, the means for diagnosing the disease, and the means of assessing the success of therapy, as well as the treatment of potential complications of heartworm infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 article

Echocardiographic quantification of Dirofilaria immitis in experimentally infected cats

Atkins, C. E., Arther, R. G., Ciszewski, D. K., Davis, W. L., Ensley, S. M., Guity, P. S., … Settje, T. L. (2008, December 10). VETERINARY PARASITOLOGY, Vol. 158, pp. 164–170.

By: C. Atkins n, R. Arther*, D. Ciszewski*, W. Davis*, S. Ensley*, P. Guity n, H. Chopade*, H. Hoss*, T. Settje*

author keywords: Heartworm diagnosis; Safety; Imidacloprid; Moxidectin; Echocardiography
MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cat Diseases / parasitology; Cat Diseases / prevention & control; Cats; Dirofilaria immitis / isolation & purification; Dirofilariasis / diagnostic imaging; Dirofilariasis / parasitology; Dirofilariasis / prevention & control; Echocardiography / standards; Echocardiography / veterinary; Female; Filaricides / adverse effects; Filaricides / pharmacology; Male; Radiography, Thoracic / veterinary; Random Allocation; Safety; Sensitivity and Specificity
TL;DR: Echocardiography is useful for detecting mature experimental heartworm infections, identifying cats that have rejected mature infection, and detecting very heavy heartworm burdens, but it is only moderately accurate in classifying lesser burdens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 personal communication

Questions terminology in heartworm infection commentary - The author responds

By: C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

2008 article

Supraventricular tachycardia in dogs: 65 cases (1990-2007)

Finster, S. T., DeFrancesco, T. C., Atkins, C. E., Hansen, B. D., & Keene, B. W. (2008, October). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 18, pp. 503–510.

By: S. Finster n, T. DeFrancesco n , C. Atkins n, B. Hansen n & B. Keene n

author keywords: atrial tachycardia; atrioventricular nodal reentry tachycardia; pre-excitation
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Use of a nitinol gooseneck snare catheter for removal of adult Dirofilaria immitis in two cats

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 233(9), 1441–1445.

By: M. Small n, C. Atkins n, S. Gordon  n, A. Birkenheuer n , M. Booth-Sayer n, B. Keene n, Y. Fujii n, M. Miller n

MeSH headings : Animals; Cardiac Catheterization / instrumentation; Cardiac Catheterization / methods; Cardiac Catheterization / veterinary; Cat Diseases / parasitology; Cat Diseases / surgery; Cats; Chylothorax / etiology; Chylothorax / parasitology; Chylothorax / surgery; Chylothorax / veterinary; Dirofilaria immitis / isolation & purification; Dirofilariasis / complications; Dirofilariasis / surgery; Female; Heart Failure / surgery; Heart Failure / veterinary; Male; Treatment Outcome
TL;DR: Findings suggested that use of a nitinol gooseneck snare catheter may be a safe and effective technique for removing adult D immitis from the right atrium and ventricle in cats and that successful removal of adult heartworms in infected cats may resolve clinical signs of right-sided congestive heart failure and chylothorax. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2007 journal article

Cardiovascular effects of acute pulmonary obstruction in horses with recurrent airway obstruction

JOURNAL OF VETERINARY INTERNAL MEDICINE, 21(2), 302–307.

By: A. Johansson, S. Gardner n, C. Atkins n, D. LaFevers n & B. Breuhaus n 

author keywords: cardiac; echocardiogram; equine; heaves
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Design and testing of a natural dirofilaria immitis infection model to evaluate the safety of an imidacloprid plus moxidectin combination in cats

Arther, R. G., AtkinS, C., Ciszewski, D. K., Davis, W. L., & Settje, T. L. (2007, August). PARASITOLOGY RESEARCH, Vol. 101, pp. S69–S76.

By: R. Arther*, C. AtkinS n, D. Ciszewski*, W. Davis* & T. Settje*

TL;DR: The results of the study indicate that cats currently infected with D. immitis can be safely treated with 10% imidacloprid + 1% moxidectin, even at dosages five-fold higher than recommended for clinical use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 review

Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats

[Review of ]. Journal of Veterinary Internal Medicine, 21(3), 542–558.

By: S. Brown *, C. Atkins n, R. Bagley*, A. Carr *, L. Cowgill *, M. Davidson n, B. Egner*, J. Elliott * ...

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Prospective clinical evaluation of an ELISA B-type natriuretic peptide assay in the diagnosis of congestive heart failure in dogs presenting with cough or dyspnea

JOURNAL OF VETERINARY INTERNAL MEDICINE, 21(2), 243–250.

By: T. DeFrancesco n , J. Rush *, E. Rozanski *, B. Hansen n, B. Keene n, D. Moore*, C. Atkins n

author keywords: brain natriuretic peptide; cardiac biomarkers; heart disease
TL;DR: Measurement of BNP is useful in establishing or in excluding the diagnosis of CHF in dogs with cough or dyspnea, and B-type natriuretic peptide concentrations rose significantly as a function of severity ofCHF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Reassessing the definition of heartworm infection in cats

Atkins, C. E. (2007, November 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 231, pp. 1338–1338.

By: C. Atkins n

MeSH headings : Animals; Antibodies, Helminth / blood; Cat Diseases / parasitology; Cat Diseases / pathology; Cats; Diagnosis, Differential; Dirofilaria immitis / immunology; Dirofilaria immitis / pathogenicity; Dirofilariasis / parasitology; Dirofilariasis / pathology; Environmental Exposure; Risk Factors
TL;DR: Three landmark works broaden the understanding of the pathophysiology of the respiratory tract signs associated with exposure to various stages of Dirofilaria immitis and raise questions as to appropriately descriptive terminology, particularly regarding the use of the word exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency

Journal of the American Veterinary Medical Association, 231(7), 1061–1069.

By: C. Atkins n, B. Keene*, W. Brown, J. Coats*, M. Crawford, T. DeFrancesco* , N. Edwards, P. Fox ...

MeSH headings : Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Antihypertensive Agents / therapeutic use; Death, Sudden, Cardiac / veterinary; Disease Progression; Disease-Free Survival; Dog Diseases / mortality; Dog Diseases / prevention & control; Dogs; Double-Blind Method; Enalapril / therapeutic use; Female; Heart Failure / mortality; Heart Failure / prevention & control; Heart Failure / veterinary; Kaplan-Meier Estimate; Male; Mitral Valve Insufficiency / complications; Mitral Valve Insufficiency / veterinary; Severity of Illness Index; Time Factors; Treatment Outcome
TL;DR: Chronic enalapril treatment of dogs with naturally occurring, moderate to severe MR significantly delayed onset of CHF, compared with placebo, on the basis of number ofCHF-free days, number of dogs free of CHFs at days 500 and study end, and increased time to a combined secondary endpoint of CHf-all-cause death. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

The effect of amlodipine and the combination of amlodipine and enalapril on the renin-angiotensin-aldosterone system in the dog

Journal of Veterinary Pharmacology and Therapeutics, 30(5), 394–400.

By: C. Atkins*, W. Rausch*, S. Gardner*, T. Defrancesco* , B. Keene* & J. Levine n 

MeSH headings : Administration, Oral; Aldosterone / urine; Amlodipine / administration & dosage; Amlodipine / blood; Amlodipine / pharmacology; Animals; Antihypertensive Agents / administration & dosage; Antihypertensive Agents / blood; Antihypertensive Agents / pharmacology; Blood Pressure / drug effects; Blood Urea Nitrogen; Dogs / metabolism; Drug Therapy, Combination; Enalapril / administration & dosage; Enalapril / blood; Enalapril / pharmacology; Heart Rate / drug effects; Male; Renin-Angiotensin System / drug effects
TL;DR: Renin-angiotensin-aldosterone system activation was increased by approximately threefold (P < 0.05) with amlodipine administration, but this effect was blunted by enalapril, such that aldosterone excretion was no longer different from that observed under control conditions, although values for 24-h ald testosterone excretion did not return to pretreament levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Coil occlusion of residual shunts after surgical closure of patent ductus arteriosus

VETERINARY SURGERY, 35(8), 781–785.

By: Y. Fujii n, B. Keene n, K. Mathews n, C. Atkins n, T. Defrancesco n , E. Hardie n, Y. Wakao n

MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / surgery; Dog Diseases / therapy; Dogs; Ductus Arteriosus, Patent / diagnostic imaging; Ductus Arteriosus, Patent / surgery; Ductus Arteriosus, Patent / therapy; Ductus Arteriosus, Patent / veterinary; Echocardiography, Doppler, Color / veterinary; Embolization, Therapeutic / methods; Embolization, Therapeutic / veterinary; Female; Ligation / adverse effects; Ligation / veterinary; Male; Treatment Outcome
TL;DR: Transcatheter coil embolization appears to be a safe and minimally invasive procedure for complete occlusion of residual PDA flow after incomplete surgical ligation and should be considered for correction of hemodynamically significant residual shunts in dogs that have incomplete PDA Occlusion after open surgical ligate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Prevalence of naturally occurring Dirofilaria immitis infection amona nondomestic cats housed in an area in which heartworms are endemic

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 227(1), 139–143.

By: C. Atkins n, A. Moresco*  & A. Litster

Contributors: C. Atkins n, A. Moresco*  & A. Litster

MeSH headings : Animals; Animals, Wild; Antibodies, Helminth / blood; Colorado / epidemiology; Cross-Sectional Studies; Dirofilaria immitis / immunology; Dirofilariasis / epidemiology; Felidae / parasitology; Female; Male; New Zealand / epidemiology; North Carolina / epidemiology; Prevalence; Queensland / epidemiology; Risk Factors; Seroepidemiologic Studies; Serologic Tests / veterinary; Sex Factors
TL;DR: It is suggested that nondomestic cats housed outdoors in the southeastern United States are at risk for heartworm exposure and infection, with male cats having a greater risk of exposure than female cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 article

Atrial fibrillation in cats: 50 cases (1979-2002)

Cote, E., Harpster, N. K., Laste, N. J., MacDonald, K. A., Kittleson, M. D., Bond, B. R., … Atkins, C. E. (2004, July 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 225, pp. 256–260.

By: E. Cote *, N. Harpster*, N. Laste*, K. MacDonald*, M. Kittleson, B. Bond*, K. Barrett*, S. Ettinger*, C. Atkins n

MeSH headings : Age Factors; Animals; Atrial Fibrillation / diagnosis; Atrial Fibrillation / drug therapy; Atrial Fibrillation / mortality; Atrial Fibrillation / veterinary; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / mortality; Cats; Diagnosis, Differential; Electrocardiography / veterinary; Female; Heart / anatomy & histology; Heart Defects, Congenital / diagnosis; Heart Defects, Congenital / drug therapy; Heart Defects, Congenital / mortality; Heart Defects, Congenital / veterinary; Male; Retrospective Studies; Sex Factors; Survival Analysis; Treatment Outcome
TL;DR: Results suggest that AF occurs primarily in older adult male cats with structural heart disease severe enough to lead to atrial enlargement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Characterization of the Pharmacokinetic and Pharmacodynamic Properties of the Angiotensin-Converting Enzyme Inhibitor, Enalapril, in Horses

Journal of Veterinary Internal Medicine, 18(2), 231–237.

By: S. Gardner n, C. Atkins n, R. Sams *, A. Schwabenton n & M. Papich n 

TL;DR: There was a tendency (P = .0625) toward a decrease in ACE activity 45-120 minutes after enalapril administration, but ACE activity suppression was never > 16%. (via Semantic Scholar)
Sources: NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2004 journal article

Feline heartworm infection

NAVC Clinician's Brief, 15.

By: C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Pharmacokinetics and pharmacodynamics of furosemide after oral administration to horses

JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(5), 739–743.

By: A. Johansson, S. Gardner*, J. Levine* , M. Papich* , D. LaFevers*, R. Goldman, M. Sheets, C. Atkins*

author keywords: equine; frusemide; loop diuretic; oral bioavailability
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Comparison of results of three commercial heartworm antigen test kits in dogs with low heartworm burdens

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 222(9), 1221–1223.

By: C. Atkins n

MeSH headings : Animals; Antigens, Helminth / blood; Dirofilaria immitis / immunology; Dirofilariasis / blood; Dirofilariasis / diagnosis; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; False Negative Reactions; False Positive Reactions; Female; Male; Reagent Kits, Diagnostic / veterinary; Reproducibility of Results; Sensitivity and Specificity
TL;DR: Results indicated that sensitivity of the 3 commercially available heartworm antigen test kits ranged from 78 to 84% when used to test serum samples from dogs with low heartworm burdens, and that sensitivity varied among test kits. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Furosemide continuous rate infusion in the horse: Evaluation of enhanced efficacy and reduced side effects

JOURNAL OF VETERINARY INTERNAL MEDICINE, 17(6), 887–895.

By: A. Johansson n, S. Gardner n, J. Levine n , M. Papich n , D. LaFevers*, L. Fuquay, V. Reagan n, C. Atkins n

author keywords: electrolyte; equine; fluid balance; frusemide; lasix; loop diuretic
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 book

Getting to the heart of the matter : advances in the management of cardiac patients

(D. K. Hurley & D. P. Devlin, Eds.). Lyon, France: Merial.

By: T. DeFrancesco, C. Atkins, K. Hurley & P. Devlin

Ed(s): D. Hurley & D. Devlin

Source: NC State University Libraries
Added: February 5, 2022

2003 journal article

Is there a better way to administer heartworm adulticidal therapy?

Veterinary Medicine, 98(4), 310-.

By: C. Atkins & M. Miller

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Noninvasive transthoracic temporary cardiac pacing in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 17, pp. 663–667.

By: T. DeFrancesco n , B. Hansen n, C. Atkins n, J. Sidley n & B. Keene n

author keywords: advanced atrioventricular block; bradyarrhythmias; pacemaker; sinus node dysfunction
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers

Journal of the American Veterinary Medical Association, 221(4), 522–527.

By: K. Meurs* , A. Spier, N. Wright, C. Atkins*, T. DeFrancesco* , S. Gordon, R. Hamlin, B. Keene* ...

MeSH headings : Animals; Anti-Arrhythmia Agents / pharmacology; Anti-Arrhythmia Agents / therapeutic use; Arrhythmias, Cardiac / drug therapy; Arrhythmias, Cardiac / veterinary; Atenolol / therapeutic use; Dog Diseases / drug therapy; Dogs; Drug Therapy, Combination; Heart Rate; Mexiletine / therapeutic use; Procainamide / therapeutic use; Random Allocation; Sotalol / therapeutic use; Syncope / drug therapy; Syncope / veterinary; Treatment Outcome; Ventricular Premature Complexes / drug therapy; Ventricular Premature Complexes / veterinary
TL;DR: Significant reductions in number of VPC, severity of arrythmia, and maximum and mean HR were observed in dogs treated with mexiletine-atenolol or sotalol; occurrence of syncope was not significantly different between these 2 treatment groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 journal article

Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation

Journal of the American Veterinary Medical Association, 221(5), 654–658.

By: C. Atkins n, W. Brown  n, J. Coats n, M. Crawford n, T. DeFrancesco n , J. Edwards n, P. Fox  n, B. Keene n ...

MeSH headings : Angiotensin-Converting Enzyme Inhibitors / adverse effects; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Blood Urea Nitrogen; Creatinine / blood; Dog Diseases / drug therapy; Dogs; Enalapril / adverse effects; Enalapril / therapeutic use; Female; Follow-Up Studies; Kidney / drug effects; Kidney Function Tests / veterinary; Male; Mitral Valve Insufficiency / complications; Mitral Valve Insufficiency / drug therapy; Mitral Valve Insufficiency / veterinary; Time Factors
TL;DR: Results suggest that administration of enalapril for up to 2 years did not have any demonstrable adverse effects on renal function in dogs with severe, compensated mitral regurgitation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 journal article

Percutaneous Balloon Pericardiotomy as a Treatment for Recurrent Pericardial Effusion in 6 Dogs

Journal of Veterinary Internal Medicine, 16(5), 541–546.

By: J. Sidley n, C. Atkins n, B. Keene n & T. DeFrancesco n 

author keywords: cardiac tamponade; chemodectoma; heart base tumor; hemangiosarcoma; idiopathic pericardial effusion
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 article

Prospective clinical evaluation of serum cardiac troponin T in dogs admitted to a veterinary teaching hospital

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 553–557.

By: T. DeFrancesco n , C. Atkins n, B. Keene n, . Coats n & M. Hauck n

author keywords: cardiomyopathy; congestive heart failure; doxorubicin-induced cardiotoxicity; neoplasia; skeletal muscle trauma
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Treatment of canine pulmonic stenosis with percutaneous balloon valvuloplasty

Veterinary Medicine, 97(11), 819–821.

By: W. Rausch & C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Natural history of hypertrophic cardiomyopathy and aortic thromboembolism in a family of domestic shorthair cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, 15(6), 595–599.

By: C. Baty  n, D. Malarkey n, C. Atkins n, T. DeFrancesco n , J. Sidley n & B. Keene n

author keywords: cardiac myocyte disarray; end stage; spontaneous echo contrast; systolic function; ventricular remodeling
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Polymerase chain reaction analysis for viruses in paraffin-embedded myocardium from dogs with dilated cardiomyopathy or myocarditis

American Journal of Veterinary Research, 62(1), 130–135.

By: T. Maxson*, K. Meurs n , L. Lehmkuhl n, A. Magnon n, S. Weisbrode n & C. Atkins n

MeSH headings : Animals; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / veterinary; Cardiomyopathy, Dilated / virology; Dog Diseases / pathology; Dog Diseases / virology; Dogs; Fibrosis; Genome, Viral; Heart / virology; Inflammation; Myocarditis / pathology; Myocarditis / veterinary; Myocarditis / virology; Myocardium / pathology; Parvovirus, Canine / genetics; Parvovirus, Canine / isolation & purification; Polymerase Chain Reaction / methods; Viruses / isolation & purification
TL;DR: Viral agents canine parvovirus, adenovirus types 1 and 2, and herpesvirus are not commonly associated with DCM or active myocarditis in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2001 journal article

Use of echocardiography for the diagnosis of heartworm disease in cats: 43 cases (1985-1997)

Journal of the American Veterinary Medical Association, 218(1), 66–69.

By: T. DeFrancesco n , C. Atkins*, M. Miller, K. Meurs*  & B. Keene*

MeSH headings : Animals; Antibodies, Helminth / analysis; Antigens, Helminth / analysis; Cat Diseases / diagnostic imaging; Cat Diseases / parasitology; Cats; Dirofilaria immitis / immunology; Dirofilaria immitis / isolation & purification; Dirofilariasis / diagnostic imaging; Echocardiography / veterinary; Pulmonary Artery / diagnostic imaging; Pulmonary Artery / pathology; Radiography, Thoracic / veterinary; Retrospective Studies
TL;DR: Although echocardiography was less sensitive than antigen testing, it was a useful adjunctive test in cats that had negative antigen test results in which there was a suspicion of heartworm disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2000 journal article

Aortic dissection and congestive heart failure associated with systemic hypertension in a cat

Journal of Veterinary Internal Medicine, 14(2), 208–213.

By: A. Wey n & C. Atkins n

Source: NC State University Libraries
Added: August 6, 2018

2000 chapter

CVT update: Diagnosis and prevention of heartworm disease in cats

In Kirk's current veterinary therapy : small animal practice (13th Ed.) (p. 782). Philadelphia, PA : W.B. Saunders.

By: C. Atkins & W. Ryan

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Heartworm infection in cats: 50 cases (1985-1997)

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 217(3), 355–358.

By: C. Atkins n, T. DeFrancesco n , . Coats n, J. Sidley n & B. Keene n

MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cats; Dirofilariasis / diagnosis; Dirofilariasis / epidemiology; Female; Male; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis
TL;DR: Findings suggested that male cats were not predisposed to HWI, domestic shorthair cats were at increased risk, and indoor housing was only partially protective, while sex does not appear to be a risk factor for HWI in cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 article

Ocular lesions associated with systemic hypertension in cats: 69 cases (1985-1998)

Maggio, F., DeFrancesco, T. C., Atkins, C. E., Pizzirani, S., Gilger, B. C., & Davidson, M. G. (2000, September 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 217, pp. 695–702.

By: F. Maggio *, T. DeFrancesco n , C. Atkins n, S. Pizzirani  n, B. Gilger n  & M. Davidson n

MeSH headings : Animals; Blindness / etiology; Blindness / veterinary; Cat Diseases / etiology; Cat Diseases / pathology; Cats; Female; Fundus Oculi; Hypertension / complications; Hypertension / pathology; Hypertension / veterinary; Male; Retinal Diseases / etiology; Retinal Diseases / pathology; Retinal Diseases / veterinary; Retrospective Studies
TL;DR: Retinal lesions, caused predominantly by choroidal injury, are common in cats with hypertension, and primary hypertension in cats may be more common than currently recognized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 personal communication

Untitled

By: C. Atkins & T. DeFrancesco 

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

A polymerase chain reaction screening strategy for the promoter of the canine dystrophin gene

American Journal of Veterinary Research, 60(9), 1040–1046.

By: S. Schatzberg, N. Olby , S. Steingold, B. Keene, C. Atkins, K. Meurs, G. Solomon, S. Goedegebuure, S. Wilton, N. Sharp

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Bartonella vinsonii subsp berkhoffi and related members of the alpha subdivision of the Proteobacteria in dogs with cardiac arrhythmias, endocarditis, or myocarditis

Journal of Clinical Microbiology, 37(11), 3618–3626.

By: E. Breitschwerdt , C. Atkins, T. Brown, D. Kordick & P. Snyder

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Evaluation of the effect of pleural effusion on central venous pressure in cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 13, pp. 561–563.

By: J. Gookin n  & C. Atkins n

author keywords: diagnosis; hemodynamic effect of pleural effusion; heart failure; hydrothorax
TL;DR: The threshold volume required to increase CVP approximated that suggested by clinical observation (22 mL/kg) and a positive linear relationship was observed between CVP and volume of PEF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

The diagnosis of feline heartworm infection

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 35(3), 185-+.

By: C. Atkins n

MeSH headings : Algorithms; Animals; Cat Diseases / diagnosis; Cat Diseases / parasitology; Cats; Dirofilariasis / diagnosis; Veterinary Medicine / methods
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Complications of heartworm disease

North American Veterinary Conference. Veterinary Proceedings, 12(1998), 556–558.

By: C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Feline heartworm disease

North American Veterinary Conference. Veterinary Proceedings, 12(1998), 551–553.

By: C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Heartworm disease: An update on testing and prevention in dogs and cats

Veterinary Medicine, 93(1), 15.

By: C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Heartworm disease: an update

North American Veterinary Conference. Veterinary Proceedings, 12(1998), 553–556.

By: C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Prevalence of heartworm infection in cats with signs of cardiorespiratory abnormalities

Journal of the American Veterinary Medical Association, 212(4), 517–520.

By: C. Atkins, T. DeFrancesco , M. Miller, K. Meurs & B. Keene

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

American Heartworm Society guidelines: Guidelines for the diagnosis, treatment, and prevention of heartworm (Dirofilaria immitis) infection in cats

Compendium on Continuing Education for the Practicing Veterinarian, 19(4), 422–429.

By: C. Atkins, R. Atwell, R. Dillon, C. Genchi, M. Hayasaki, R. Holmes, D. Knight, D. Lukof, J. McCall, J. Slocombe

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

ECG of the month. Sinus arrhythmia in a dog

Journal of the American Veterinary Medical Association, 211(9), 1126–1127.

By: S. Bliss & C. Atkins

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Feline heartworm disease

Feline Practice, 25(2), 12.

By: R. Dillon, C. Atkins, T. Clekis, C. Genchi, D. Knight, J. McCall, M. Miller

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Systemic arterial dirofilariasis in five dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 11(3), 189–194.

By: . Frank*, F. Nutter  n, A. Kyles n, C. Atkins n & R. Sellon n

MeSH headings : Animals; Arsenamide / therapeutic use; Arsenicals / therapeutic use; Arteries / parasitology; Arteries / pathology; Dirofilariasis / drug therapy; Dirofilariasis / pathology; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; Filaricides / therapeutic use; Male; Triazines / therapeutic use
TL;DR: The treatment of systemic arterial dirofilariasis creates a therapeutic challenge because of multiple potential complications resulting from thromboembolic disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1995 book

Diagnostic cardiology

Guelph, Ontario: Lifelearn V.

By: J. Goodwin, C. Atkins & L. Tilley

Source: NC State University Libraries
Added: February 5, 2022

1995 journal article

ORTHODROMIC RECIPROCATING TACHYCARDIA AND HEART-FAILURE IN A DOG WITH A CONCEALED POSTEROSEPTAL ACCESSORY PATHWAY

JOURNAL OF VETERINARY INTERNAL MEDICINE, 9(1), 43–49.

By: C. Atkins n, R. Kanter*, K. Wright, Z. Saba*, C. Baty, C. Swanson n, S. Bai n, B. Keene

MeSH headings : Animals; Dog Diseases / drug therapy; Dog Diseases / physiopathology; Dogs; Heart Conduction System / abnormalities; Heart Conduction System / physiopathology; Heart Failure; Male; Procainamide / therapeutic use; Tachycardia, Atrioventricular Nodal Reentry / drug therapy; Tachycardia, Atrioventricular Nodal Reentry / physiopathology; Tachycardia, Atrioventricular Nodal Reentry / veterinary
TL;DR: Increasing the oral procainamide dose to achieve such plasma concentrations was successful in eliminating orthodromic reciprocating tachycardia, preventing heart failure, and returning Doppler indices of diastolic function to normal. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1994 journal article

Acute effect of hydralazine administration on pulmonary artery hemodynamics in dogs with chronic heartworm disease

American Journal of Veterinary Research, 55(2), 262.

By: C. Atkins, B. Keene, S. McGuirk & T. Sato

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

ECG of the month [Supraventricular tachycardia in a dog]

Journal of the American Veterinary Medical Association, 205(7), 983.

By: C. Atkins, J. Cali & P. Lombardo

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

CARDIOVASCULAR EFFECTS AND FATALITIES ASSOCIATED WITH INTRAVENOUS ADMINISTRATION OF DOXYCYCLINE TO HORSES AND PONIES

EQUINE VETERINARY JOURNAL, 24(1), 41–45.

By: J. Riond*, J. Riviere*, W. Duckett n, C. Atkins n, A. Jernigan*, Y. Rikihisa *, S. Spurlock

MeSH headings : Animals; Blood Pressure / drug effects; Cardiovascular System / drug effects; Doxycycline / administration & dosage; Doxycycline / adverse effects; Electrocardiography / veterinary; Electrolytes / blood; Female; Heart / drug effects; Heart Rate / drug effects; Horses / physiology; Infusions, Intravenous / veterinary; Male; Muscles / drug effects; Respiration / drug effects
TL;DR: Results of the present study suggest that the intravenous use of doxycycline should be avoided in horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1992 journal article

Risk factors, clinical signs, and survival in cats with a clinical diagnosis of idiopathic hypertrophic cardiomyopathy: 74 cases (1985-1989)

Journal of the American Veterinary Medical Association, 201(4), 613.

By: C. Atkins, A. Gallo, I. Kurzman & P. Cowen

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

SYSTOLIC-TIME INTERVALS AND THEIR DERIVATIVES FOR EVALUATION OF CARDIAC-FUNCTION

JOURNAL OF VETERINARY INTERNAL MEDICINE, 6(2), 55–63.

By: C. Atkins n & P. Snyder n

MeSH headings : Animals; Cats / physiology; Dogs / physiology; Electrocardiography / veterinary; Heart / physiology; Heart Rate; Reproducibility of Results; Systole; Ventricular Function
TL;DR: Their utility and weaknesses, as well as the effects of heart rate, loading conditions, cardiac contractility, and drug therapies on systolic time intervals are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1992 journal article

THE USE OF M-MODE ECHOCARDIOGRAPHY IN DETERMINING CARDIAC-OUTPUT IN DOGS WITH NORMAL, LOW, AND HIGH OUTPUT STATES - COMPARISON TO THERMODILUTION METHOD

VETERINARY RADIOLOGY & ULTRASOUND, 33(5), 297–304.

By: C. Atkins n, M. Curtis *, S. Mcguirk, M. Kittleson *, T. Sato  n & P. Snyder*

author keywords: CARDIAC OUTPUT; ECHOCARDIOGRAPHY; DOBUTAMINE; HEART DISEASE; HEARTWORMS; DILATED CARDIOGRAPHY
TL;DR: In normal dogs, while echocardiographic estimation of CI is significantly related to CI measured with thermodilution, individual variation diminishes clinical utility, and this noninvasive technique should prove useful in comparing populations with minimal or no cardiac dysfunction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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