Charlotte E Farin

Works (50)

Updated: August 16th, 2024 13:37

2021 article

Assessing puberty in female cheetahs (Acinonyx jubatus) via faecal hormone metabolites and body weight

Maly, M. A., Edwards, K. L., Farin, C. E., Koester, D. C., & Crosier, A. E. (2021, November 30). REPRODUCTION FERTILITY AND DEVELOPMENT.

By: M. Maly n, K. Edwards *, C. Farin n, D. Koester * & A. Crosier *

author keywords: Acinonyx jubatus; cheetahs; development; endocrinology; glucocorticoid; growth; oestrogen; puberty
MeSH headings : Acinonyx; Animals; Body Weight / physiology; Estrogens / analysis; Estrogens / metabolism; Feces / chemistry; Female; Glucocorticoids / analysis; Sexual Maturation / physiology
TL;DR: Characterisation ofCheetah puberty has direct and significant implications for the improvement of management and reproductive success of cheetahs under human care and is particularly informative for identifying important windows of development, littermate dispersal and breeding introductions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: December 6, 2021

2019 journal article

Individual and environmental risk factors associated with fecal glucocorticoid metabolite concentrations in zoo-housed Asian and African elephants

PLOS One, 14(9), e0217326.

By: J. Brown *, J. Bray n, K. Carlstead*, D. Dickey n, C. Farin n & K. Ange-van Heugten n 

Ed(s): E. Hillmann

MeSH headings : Animals; Animals, Zoo; Biomarkers; Elephants / metabolism; Environment; Feces / chemistry; Female; Glucocorticoids / metabolism; Male; Risk Factors; Seasons
TL;DR: Results indicate that African elephants are more responsive to social stressors than Asians, and that poor joint health is a stress-related welfare problem for Asian, but not African elephants in the North American population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: October 7, 2019

2018 journal article

Assessing puberty in ex situ male cheetahs (Acinonyx jubatus) via fecal hormone metabolites and body weights

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 268, 22–33.

By: M. Maly n, K. Edwards *, C. Farin n, D. Koester * & A. Crosier *

author keywords: Glucocorticoids; Androgens; Sexual maturity; Population management
MeSH headings : Acinonyx; Animals; Body Weight / physiology; Cats; Feces / chemistry; Hormones / metabolism; Male; Puberty / metabolism; Sexual Maturation
TL;DR: Knowing about the physiological changes associated with puberty is useful for management and improving reproductive success of cheetah populations under human care, particularly for determining timing of litter separation from dam, littermate dispersal and when to introduce potential breeding pairs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: October 29, 2018

2018 journal article

Assessment of ovulation synchronization protocols in goats and use of pregnancy specific protein B (PSPB) enzyme linked immunsorbent assay (ELISA) to determine kid number at birth

DOMESTIC ANIMAL ENDOCRINOLOGY, 67, 54–62.

By: A. Llanes n, C. Whisnant n, W. Knox n & C. Farin n

author keywords: Pregnancy; Artificial insemination; PSPB; Ovulation synchronization; Small ruminants
MeSH headings : Animals; Delayed-Action Preparations; Dinoprost / administration & dosage; Drug Delivery Systems / instrumentation; Enzyme-Linked Immunosorbent Assay / veterinary; Equipment Reuse / veterinary; Estrus Synchronization / methods; Female; Gestational Age; Goats / blood; Goats / physiology; Gonadotropin-Releasing Hormone / administration & dosage; Insemination, Artificial / methods; Insemination, Artificial / veterinary; Litter Size; Ovulation / physiology; Pregnancy; Pregnancy Outcome; Pregnancy-Specific beta 1-Glycoproteins / analysis; Progesterone / administration & dosage
TL;DR: Reuse of CIDRs, even with reuse extending for a total of 21 d, was as effective as new CIDR for synchronization of ovulation, and PSPB concentrations detected using a commercially available ELISA at Day 48 or 85 of gestation could distinguish does carrying single versus multiple fetuses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 29, 2019

2016 journal article

Differences in mRNA populations of short and long bovine conceptuses on Day 15 of gestation

MOLECULAR REPRODUCTION AND DEVELOPMENT, 83(5), 424–441.

By: C. Barnwell n, P. Farin n, C. Ashwell n , W. Farmer n, S. Galphin n & C. Farin n

MeSH headings : Animals; Cattle; Female; Gestational Age; Morula / cytology; Morula / metabolism; Pregnancy; RNA, Messenger / metabolism
TL;DR: Differences in gene expression were identified between conceptuses recovered on Day 15 of gestation, based on their length, which may be used to identify genes and cellular pathways involved in enhanced conceptus elongation that could serve as markers of successful pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

11 COMPARISON OF CONTROLLED INTERNAL DRUG-RELEASE INSERT–BASED AND PROGESTERONE-FREE METHODS FOR OVULATION SYNCHRONIZATION AND TIMED ARTIFICIAL INSEMINATION OF GOATS

Reproduction, Fertility and Development, 28(2), 135.

By: A. Llanes n, W. Knox  n & C. Farin n

TL;DR: The objective of this study was to test the efficacy of reusing CIDR for OvSynch-TAI compared with that for a progesterone-free Ov synchTAI protocol (NCS) or a breed by oestrus detection (ED) control. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: February 21, 2020

2015 journal article

Maternal serum progesterone concentration and early conceptus development of bovine embryos produced in vivo or in vitro

DOMESTIC ANIMAL ENDOCRINOLOGY, 52, 75–81.

By: C. Barnwell n, P. Farin n, C. Whisnant n, J. Alexander n & C. Farin n

author keywords: Cattle; Embryo; Conceptus; Progesterone; In vitro production; Embryo transfer
MeSH headings : Animals; Blastocyst / physiology; Cattle / embryology; Embryo Transfer / veterinary; Embryonic Development / physiology; Female; Fertilization in Vitro / veterinary; Gestational Age; Male; Pregnancy; Progesterone / blood; Superovulation
TL;DR: Differences in autonomy may exist between in vitro- and in vivo-produced embryos during the period of conceptus elongation with in vitro/in vivo- produced embryos relying more on intrinsic factors to influence elongation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Abnormal offspring syndrome

Bovine Reproduction, 620–638.

By: C. Farin n, C. Barnwell n & W. Farmer n

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Expression of antisense of insulin-like growth factor-2 receptor RNA non-coding (AIRN) during early gestation in cattle

Animal Reproduction Science, 138(1-2), 64–73.

By: W. Farmer n, P. Farin n, J. Piedrahita n , S. Bischoff  n & C. Farin n

author keywords: Bovine; IGF2R; Antisense RNA; Embryo; Fetus
MeSH headings : Animals; Cattle / embryology; Embryo, Mammalian / metabolism; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Liver / metabolism; Male; Pregnancy; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Untranslated / genetics; Receptor, IGF Type 2 / genetics; Receptor, IGF Type 2 / metabolism; Reverse Transcriptase Polymerase Chain Reaction / veterinary
TL;DR: BAIRN was not expressed in blastocyst-stage embryos, was expressed in an increasing proportion of embryos around the time of maternal recognition of pregnancy and was expressed following implantation, indicating relative levels of bAIRN in bovine fetal liver can be altered by method of embryo production. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2012 journal article

NCSynch: A novel, progestagen-free protocol for ovulation synchronization and timed artificial insemination in goats

SMALL RUMINANT RESEARCH, 110(1), 42–45.

By: E. Bowdridge  n, W. Knox n, C. Whisnant n & C. Farin n

author keywords: Goat; Estrus synchronization; Ovulation synchronization; Timed artificial insemination
TL;DR: Pregnancy success following the use of NCSynch-TAI was comparable to that obtained when does were bred based on detection of estrus, and kidding rates also recorded. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

140 CHARACTERIZATION OF THE BOVINE ANTISENSE TO INSULIN-LIKE GROWTH FACTOR TYPE 2 RECEPTOR (bAIRN) NONCODING RNA

Reproduction, Fertility and Development, 24(1), 182.

By: W. Farmer  n, P. Farin n & C. Farin n

TL;DR: The full-length b AIRN ncRNA has been characterised and a strong putative polyadenylation signal was identified at 65.4 kb downstream from the bAIRN promoter, suggesting prior termination of the bairN transcript. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2011 journal article

80 RECIPIENT SERUM PROGESTERONE CONCENTRATION AND EARLY CONCEPTUS DEVELOPMENT IN BOVINE EMBRYOS PRODUCED IN VIVO OR IN VITRO

Reproduction, Fertility and Development, 24(1), 152.

By: C. Barnwell n, C. Whisnant  n, C. Farin n, J. Alexander n & P. Farin n

TL;DR: Serum progesterone concentrations in recipients at the time of transfer of in vivo- or in vitro-produced embryos were associated with conceptus development at Day 17 of gestation, and heifers with in vitro produced embryos had lower progester one levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2010 journal article

Effect of season on fresh and cryopreserved stallion semen

Animal Reproduction Science, 119(3-4), 219–227.

By: N. Wrench n, W. Flowers n , C. Farin n, D. Dix*, C. Pinto * & G. Klinefelter*

author keywords: Stallion; Cryopreservation; SP22; mRNA; Season; Semen
MeSH headings : Actins / genetics; Animals; Breeding; Cryopreservation / veterinary; Horses; Hot Temperature; Male; Microtubule-Associated Proteins / analysis; RNA, Messenger / analysis; Reverse Transcriptase Polymerase Chain Reaction; Seasons; Semen Preservation / veterinary; Sperm Motility; Spermatozoa / abnormalities; Spermatozoa / chemistry; Spermatozoa / physiology
TL;DR: Based on data analyzed, semen collected in the Northern Hemisphere between March and June may be best suited for cryopreservation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2010 journal article

Expression of messenger RNAs for insulin-like growth factors and their receptors in bovine fetuses at early gestation from embryos produced in vivo or in vitro

THERIOGENOLOGY, 74(7), 1288–1295.

By: C. Farin n, J. Alexander n & P. Farin n

author keywords: Embryo; In vitro production; Abnormal Offspring Syndrome; Gene expression; IGF
MeSH headings : Animals; Cattle; Female; Fertilization in Vitro / veterinary; Fetus / metabolism; Gene Expression Regulation, Developmental / physiology; Liver / metabolism; Male; Muscle, Skeletal / metabolism; Pregnancy; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptor, IGF Type 1 / genetics; Receptor, IGF Type 1 / metabolism; Receptor, IGF Type 2 / genetics; Receptor, IGF Type 2 / metabolism; Somatomedins / genetics; Somatomedins / metabolism
TL;DR: In conclusion, in vitro embryo culture was associated with subtle changes in fetal development as well as altered expression of both imprinted and non-imprinted genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 article

Pregnancy recognition and abnormal offspring syndrome in cattle

REPRODUCTION FERTILITY AND DEVELOPMENT, Vol. 22, pp. 75–87.

By: C. Farin n, W. Farmer n & P. Farin n

author keywords: AIRN; embryo; fetus; in vitro production; insulin-like growth factor receptor 2
MeSH headings : Animals; Cattle / physiology; Congenital Abnormalities / genetics; Congenital Abnormalities / veterinary; Embryonic Development / genetics; Embryonic Development / physiology; Female; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / physiology; Pregnancy; Pregnancy, Animal / genetics; Pregnancy, Animal / physiology; RNA, Antisense / genetics; RNA, Antisense / physiology; Receptors, Somatomedin / genetics; Receptors, Somatomedin / physiology; Syndrome; Uterus / physiology
TL;DR: The present review addresses the development of the post-hatching bovine conceptus, its interactions with the maternal system and changes in development that can occur as a result of in vivo and in vitro manipulations of the bovines embryo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Undergraduate performance in a domestic animal laboratory taught via distance education

JOURNAL OF ANIMAL SCIENCE, 89(1), 297–301.

By: J. Bing n, S. Pratt-Phillips  n, L. Gillen n & C. Farin n

author keywords: anatomy; distance education; laboratory; teaching; undergraduate
MeSH headings : Anatomy, Comparative / education; Animals; Animals, Domestic / anatomy & histology; Curriculum; Education, Distance; North Carolina; Students; Time Factors; Universities
TL;DR: The results of this study support the conclusion that anatomy material can be taught effectively by distance education methods. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

2 DETECTION OF ANTISENSE TO Igf2r (AIR) RNA IN CATTLE

Reproduction, Fertility and Development, 20(1), 81.

By: W. Farmer, P. Farin, S. Bischoff, J. Alexander, J. Piedrahita*  & C. Farin*

TL;DR: The antisense ncRNA, Air, does exist in cattle and its relative expression is greatest following implantation, suggesting that bAir may be involved in regulating imprinted expression of Igf2r in cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2008 journal article

201 LIVER AND KIDNEY FUNCTION IN BOVINE FETUSES FROM EMBRYOS PRODUCED IN VIVO OR IN VITRO

Reproduction, Fertility and Development, 20(1), 180.

By: P. Farin, D. Malarkey, J. Alexander & C. Farin*

TL;DR: Fets from in vitro-produced embryos had increased body weight, normal liver and kidney morphology, and increased concentrations of BUN during late gestation, compared with bovine fetuses from in vivo- produced embryos. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: August 28, 2020

2008 journal article

247 CANDIDATE mRNA REGULATING MEIOTIC RESUMPTION IN BOVINE CUMULUS-OOCYTE COMPLEXES

Reproduction, Fertility and Development, 21(1), 221.

By: J. Hicks n & C. Farin n

TL;DR: The period required for transcription initiation in bovine COC was defined, the pattern of expression for Nr4A1 and Egr1 mRNAs was determined, and small interfering RNA (siRNA) was reduced to determine the effect on GVBD. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Effect of season on sperm membrane protein 22 and selected mRNAs in fresh and cryopreserved stallion sperm

Animal Reproduction Science, 107(3-4), 357.

By: N. Wrench n, C. Pinto  n, G. Klinefelter*, D. Dix*, W. Flowers n  & C. Farin n

Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2008 article

SUBCUTANEOUS ADMINISTRATION OF FOLLICLE STIMULATING HORMONE FOR SUPEROVULATION OF HOLSTEIN COWS

REPRODUCTION FERTILITY AND DEVELOPMENT, Vol. 21, pp. 243–244.

By: P. Farin n, K. Dowdall n, J. Hicks n, C. Farin n & C. Whisnant n

TL;DR: Administration of FSH using 3 SC injections in combination with a progesterone-releasing device was an effective method for superovulation of Holstein cows and there was no effect of route of F SH administration on the concentrations of serum FSH at any time point. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Nonoxynol-9-alpha-cyclodextrin inclusion compound and its application for the controlled release of nonoxynol-9 spermicide

JOURNAL OF APPLIED POLYMER SCIENCE, 106(6), 4104–4109.

By: H. Whang n, M. Hunt n, N. Wrench n, J. Hockney n, C. Farin n & A. Tonelli n

author keywords: cyclodextrins; inclusion complexes; nonoxynol-9 spermicide; silicone elastomer; bovine sperm
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

324 FUNCTIONAL ANALYSIS USING SHORT-INTERFERING (si)RNA OF TRAM-6, A NOVEL TRANSCRIPT ASSOCIATED WITH OOCYTES MATURATION IN CATTLE

Reproduction, Fertility and Development, 18(2), 269.

By: C. Farin*, J. Sommer, K. Rodriguez, R. Petters & J. Alexander

TL;DR: Differential mRNA display was used to identify a novel transcript associated with maturation of COCs (TRAM-6) that is expressed during early maturation but not when maturation is inhibited by DRB, and siRNAs targeted against TRAM- 6 mRNA to assess its functional role in oocyte maturation. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2006 journal article

Identification of candidate mRNAs associated with gonadotropin-induced maturation of murine cumulus oocyte complexes using serial analysis of gene expression

PHYSIOLOGICAL GENOMICS, 27(3), 318–327.

By: K. Rodriguez n, L. Blomberg*, K. Zuelke*, J. Miles  n, J. Alexander n & C. Farin n

MeSH headings : Animals; Cell Culture Techniques; Cell Separation; Dichlororibofuranosylbenzimidazole / pharmacology; Female; Follicle Stimulating Hormone / metabolism; Gene Expression Profiling / methods; Meiosis / drug effects; Meiosis / genetics; Mice; Oocytes / drug effects; Oocytes / physiology; Ovary / cytology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Transcription, Genetic / drug effects
TL;DR: The critical period of transcription required for GVBD occurred between 15 and 30 min after culture initiation, and 39 and 27 transcripts were identified as differentially expressed at the P < or = 0.01 and P </= 0.001 levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

The role of transcription in EGF- and FSH-mediated oocyte maturation in vitro

ANIMAL REPRODUCTION SCIENCE, 98(1-2), 97–112.

By: C. Farin n, K. Rodriguez*, J. Alexander n, J. Hockney n, J. Herrick * & S. Kennedy-Stoskopf n

author keywords: meiosis; FSH; EGF; oocyte maturation; gene transcription
MeSH headings : Animals; Cell Culture Techniques; Dichlororibofuranosylbenzimidazole / pharmacology; Epidermal Growth Factor / pharmacology; Female; Follicle Stimulating Hormone / pharmacology; Horses; Mammals; Mice; Mitosis; Oocytes / drug effects; Oocytes / physiology; Transcription, Genetic
TL;DR: Results presented support the conclusions that EGF-induced oocytes maturation does not require nascent gene transcription in both mice and domestic cats and FSH requires gene transcription to induce oocyte maturation in both species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Effects of embryo culture on angiogenesis and morphometry of bovine placentas during early gestation

BIOLOGY OF REPRODUCTION, 73(4), 663–671.

By: . Miles  n, C. Farin n, K. Rodriguez n, J. Alexander n & P. Farin n

author keywords: developmental biology; embryo; gene regulation; in vitro fertilization; placenta
MeSH headings : Animals; Blastocyst / physiology; Blood Vessels / anatomy & histology; Cattle; Coculture Techniques; Culture Media / pharmacology; Culture Media, Serum-Free / pharmacology; Embryo Culture Techniques; Embryo, Mammalian / anatomy & histology; Female; Fertilization in Vitro / methods; Gene Expression; Gene Expression Regulation, Developmental; Gestational Age; Neovascularization, Physiologic; PPAR gamma / genetics; PPAR gamma / metabolism; Placenta / anatomy & histology; Placenta / blood supply; Placenta / drug effects; Pregnancy; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Placentas from embryos produced in vitro using a semidefined culture system exhibited a greater degree of aberrant development of the placenta during early gestation than with placentas produced in vivo or in vivo using an undefined culture system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 article

Errors in development of fetuses and placentas from in vitro-produced bovine embryos

Farin, P. W., Piedrahita, J. A., & Farin, C. E. (2006, January 7). THERIOGENOLOGY, Vol. 65, pp. 178–191.

By: P. Farin n, J. Piedrahita n  & C. Farin n

author keywords: bovine; embryo culture; nuclear transfer; fetus; placenta
MeSH headings : Animals; Breeding / methods; Cattle / embryology; Embryo Culture Techniques / methods; Embryo Culture Techniques / veterinary; Embryo Transfer / veterinary; Embryonic Development; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental; Male; Nuclear Transfer Techniques; Phenotype; Placenta / blood supply; Placenta / physiology; Placentation; Pregnancy; Pregnancy Complications / epidemiology; Pregnancy Complications / veterinary; Pregnancy Outcome / veterinary
TL;DR: The term 'abnormal offspring syndrome (AOS)' is introduced and a classification system of developmental outcomes is proposed to facilitate research efforts on the mechanisms of the various abnormal phenotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

233EXPRESSION OF INSULIN-LIKE GROWTH FACTOR (IGF) MRNA IN BOVINE CONCEPTUSES FROM EMBRYOS PRODUCED IN VIVO OR IN VITRO

Reproduction, Fertility and Development, 16(2), 237.

By: C. Farin n, J. Alexander n, K. Rodriguez  n & P. Farin n

TL;DR: The objective of this study was to determine the effect of in vitro embryo production (IVP) on expression of mRNAs for IGF-1, IGF-2, IGF -1 receptor (IGF-1R), IGF- 2R and GAPDH in bovine conceptuses at Day 17 of gestation. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2004 journal article

279VASCULAR MORPHOMETRY OF BOVINE PLACENTOMES IN LATE GESTATION FROM EMBRYOS PRODUCED IN VIVO OR IN VITRO

Reproduction, Fertility and Development, 16(2), 259.

By: J. Miles  n, C. Farin n, K. Rodriguez  n, J. Alexander n & P. Farin n

TL;DR: Compared to placentomes from embryos produced in vivo, placentome sections from embryosproduced in vitro had similar volume density of fetal vessels, but had significantly increased volumedensity of maternal vessels during late gestation. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2004 journal article

35 Analysis of Epigenetic Modifications and Genomic Imprinting in Nuclear Transfer Derived Bos Gaurus×B. Taurus Concepti

Reproduction, Fertility and Development, 16(2), 140.

By: S. Dindot *, P. Farin*, C. Farin*, J. Alexander *, E. Crosier*, S. Walker*, C. Long*, J. Piedrahita* 

TL;DR: The use of a bovine interspecies model for the assessment and characterization of epigenetic modifications and genomic imprinting in 40-day-old female nuclear transfer (NT)-derived fetuses and placentas and methylation analysis of the XIST Differentially Methylated Region indicates that cloning is associated with increased levels of methylation in selected genomic regions in the chorion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 29, 2020

2004 journal article

Angiogenesis and morphometry of bovine placentas in late gestation from embryos produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 71(6), 1919–1926.

By: . Miles  n, C. Farin n, K. Rodriguez n, J. Alexander n & P. Farin n

author keywords: developmental biology; embryo; gene regulation; in vitro fertilization; placenta
MeSH headings : Animals; Blood Vessels / anatomy & histology; Cattle; Chorionic Villi / anatomy & histology; Female; Fetal Weight; Gestational Age; Neovascularization, Physiologic; PPAR gamma / genetics; PPAR gamma / metabolism; Placenta / anatomy & histology; Placenta / blood supply; Pregnancy; RNA, Messenger / metabolism; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Findings are consistent with the concept that compensatory mechanisms exist in the vascular beds of placentas from bovine embryos produced in vitro. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Epigenetic and genomic imprinting analysis in nuclear transfer derived Bos gaurus/Bos taurus hybrid fetuses

Biology of Reproduction, 71(2), 470–478.

By: S. Dindot n, P. Farin n, C. Farin n, J. Romano*, S. Walker*, C. Long, J. Piedrahita n 

MeSH headings : Animals; Cattle; Chimera / genetics; Cloning, Organism; DNA Methylation; DNA, Satellite; Embryonic Development; Epidermis / physiology; Epigenesis, Genetic / genetics; Exons; Female; Fibroblasts / physiology; Genomic Imprinting / genetics; Genotype; Insulin-Like Growth Factor II / genetics; Keratins / genetics; Nuclear Transfer Techniques; Placenta; Pregnancy; Promoter Regions, Genetic; Proteins / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics
TL;DR: The use of a bovine interspecies model for the assessment and characterization of epigenetic modifications and genomic imprinting in Day 40-old female NT-derived fetuses and placenta indicates that the nuclear transfer process affects gene expression patterns in the trophectoderm- and inner cell mass-derived tissues to different extents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2004 article

Gene transcription and regulation of oocyte maturation

REPRODUCTION FERTILITY AND DEVELOPMENT, Vol. 16, pp. 55–67.

By: K. Rodriguez n & C. Farin n

author keywords: amanitin; bovine; 5,6-dicholoro-1-beta-D-ribofuranosyl-benzimidazole; follicle-stimulating hormone; gonadotropins; meiosis; murine
TL;DR: By understanding the molecular mechanisms underlying gonadotropin-induced maturation, improvement in oocyte maturation technologies may be expected as procedures to manipulate specific factors involved in signalling for resumption of meiosis are identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Pregnancy loss associated with embryo technologies in cattle

Medecin Veterinaire Du Quebec, 34(1), 62.

By: P. Farin, J. Miles & C. Farin

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Developmental capacity of bovine cumulus oocyte complexes after transcriptional inhibition of germinal vesicle breakdown

THERIOGENOLOGY, 61(7-8), 1499–1511.

By: K. Rodriguez n & C. Farin n

author keywords: oocyte; meiosis; transcription; blastocyst; bovine
MeSH headings : Animals; Cattle / embryology; Cells, Cultured; Cleavage Stage, Ovum / physiology; Culture Techniques; Dichlororibofuranosylbenzimidazole / pharmacology; Embryonic and Fetal Development; Estradiol / administration & dosage; Female; Fertilization in Vitro / veterinary; Follicle Stimulating Hormone / administration & dosage; Kinetics; Meiosis / drug effects; Nucleic Acid Synthesis Inhibitors / pharmacology; Oocytes / drug effects; Oocytes / physiology; Ovarian Follicle / physiology; Transcription, Genetic / drug effects; Zygote / physiology
TL;DR: Bovine COC maintained in meiotic arrest for 20 h by culture in the presence of the transcriptional inhibitor DRB retained their capacity to develop to the blastocyst stage after fertilization in vitro. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Development of skeletal muscle and expression of candidate genes in bovine fetuses from embryos produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 67(2), 401–408.

By: A. Crosier n, C. Farin n, K. Rodriguez n, P. Blondin n, J. Alexander n & P. Farin n

author keywords: conceptus; developmental biology; embryo; fetus; gene regulation; in vitro fertilization
MeSH headings : Animals; Blastocyst / physiology; Body Weight / physiology; Cattle; DNA Primers; Electrophoresis, Agar Gel; Embryo Transfer; Embryonic and Fetal Development / physiology; Female; Fertilization in Vitro; Fetus / metabolism; Gene Expression Regulation, Developmental / genetics; Glyceraldehyde-3-Phosphate Dehydrogenases / metabolism; In Vitro Techniques; Indicators and Reagents; Male; Muscle Fibers, Skeletal / physiology; Muscle Proteins / biosynthesis; Muscle Proteins / genetics; Muscle, Skeletal / anatomy & histology; Muscle, Skeletal / embryology; Pregnancy; RNA / biosynthesis; RNA / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: In vitro production of embryos resulted in fetuses with altered development of skeletal muscle fibers, and myostatin was identified as the candidate gene whose expression may contribute to the observed changes in muscle development of these fetuses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Roles of gene transcription and PKA subtype activation in maturation of murine oocytes

Reproduction (Cambridge, England), 123(6), 799–806.

By: K. Rodriguez n, R. Petters n, A. Crosier n & C. Farin n

MeSH headings : Amanitins / pharmacology; Animals; Cells, Cultured; Chorionic Gonadotropin / pharmacology; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases / antagonists & inhibitors; Cyclic AMP-Dependent Protein Kinases / metabolism; Dichlororibofuranosylbenzimidazole / pharmacology; Enzyme Activation / physiology; Enzyme Inhibitors / pharmacology; Female; Follicle Stimulating Hormone / pharmacology; Isoenzymes / metabolism; Mice; Mice, Inbred Strains; Oogenesis / physiology; Transcription, Genetic / drug effects; Transcription, Genetic / physiology
TL;DR: Results indicate that, in cultured murine COCs, FSH binding to cumulus cells results in the activation of type II PKA, which, in turn, mediates a downstream transcriptional event required for the initiation of GVBD. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2001 article

Influence of in vitro systems on embryo survival and fetal development in cattle

Farin, P. W., Crosier, A. E., & Farin, C. E. (2001, January 1). THERIOGENOLOGY, Vol. 55, pp. 151–170.

By: P. Farin n, A. Crosier n & C. Farin n

author keywords: bovine; embryo; fetus; in vitro production; gene expression; large offspring syndrome
MeSH headings : Animals; Cattle / embryology; Culture Techniques; Embryo Transfer / veterinary; Embryo, Mammalian / physiology; Embryo, Mammalian / ultrastructure; Embryonic and Fetal Development; Female; Fertilization in Vitro / veterinary; Pregnancy
TL;DR: Findings indicate that exposure to some in vitro environments during the first 7 days of life can profoundly influence fetal and placental development in cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Ultrastructural morphometry of bovine blastocysts produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 64(5), 1375–1385.

By: A. Crosier n, P. Farin n, M. Dykstra n, J. Alexander n & C. Farin n

author keywords: early development; IVF/ART
MeSH headings : Animals; Apoptosis; Blastocyst / ultrastructure; Blastomeres / ultrastructure; Cattle / embryology; Cell Nucleus / ultrastructure; Culture Media; Culture Techniques; Cytoplasm / ultrastructure; Fertilization in Vitro / veterinary; Microscopy, Electron; Mitochondria / ultrastructure; Superovulation; Vacuoles / ultrastructure
TL;DR: Blastocysts produced in vitro possessed deviations in volume densities of organelles associated with cellular metabolism as well as deviations associated with altered embryonic differentiation, however, the specific nature of these deviations varied with the type of culture conditions used for in vitro embryo production. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

In vitro production of embryos alters levels of insulin-like growth factor-II messenger ribonucleic acid in bovine fetuses 63 days after transfer

BIOLOGY OF REPRODUCTION, 62(2), 384–389.

By: P. Blondin n, P. Farin n, A. Crosier n, J. Alexander n & C. Farin n

MeSH headings : Animals; Cattle; Embryo Transfer; Embryo, Mammalian / metabolism; Female; Fertilization in Vitro; Fetus / metabolism; Gestational Age; In Vitro Techniques; Insulin-Like Growth Factor II / biosynthesis; Liver / metabolism; Muscle, Skeletal / metabolism; Pregnancy; RNA, Messenger / biosynthesis; RNA, Ribosomal / biosynthesis; Ribonucleases / analysis
TL;DR: Fetuses originating from in vitro production systems possessed altered levels of IGF-II mRNA in both liver and skeletal muscle at Day 70 of gestation, according to the objective of this study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Influence of vitamin A injection before mating on oocyte development, follicular hormones, and ovulation in gilts fed high-energy diets

Journal of Animal Science, 78(6), 1598–1607.

By: S. Whaley n, V. Hedgpeth n, C. Farin n, N. Martus n, F. Jayes  n & J. Britt n 

MeSH headings : Animal Feed; Animals; Dinoprost / metabolism; Embryonic and Fetal Development / drug effects; Energy Metabolism; Estradiol / metabolism; Female; Follicle Stimulating Hormone / blood; Granulosa Cells / drug effects; Granulosa Cells / metabolism; Insulin-Like Growth Factor I / metabolism; Luteinizing Hormone / blood; Oocytes / drug effects; Oocytes / growth & development; Ovulation / drug effects; Progesterone / metabolism; Sexual Behavior, Animal / drug effects; Swine / metabolism; Vitamin A / pharmacology
TL;DR: Evidence is provided that vitamin A may influence embryonic development by advancing resumption of meiosis and altering follicular hormonal environment during follicle maturation and treatment with vitamin A in vivo did not affect LH-stimulated or unstimulated secretion of progesterone by granulosa cells in vitro. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2000 journal article

Insulin-like growth factor I receptor Mrna and protein expression in pig corpora lutea

Journal of Reproduction & Fertility, 120(1), 109–114.

By: Z. Ge n, W. Nicholson*, D. Plotner*, C. Farin* & J. Gadsby* 

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2000 journal article

Ultrastructural morphometry of bovine compact morulae produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 62(5), 1459–1465.

By: A. Crosier n, P. Farin n, M. Dykstra n, J. Alexander n & C. Farin n

MeSH headings : Animals; Cattle; Cell Culture Techniques / methods; Cytoplasm; Female; Fertilization in Vitro; Morula / cytology; Morula / ultrastructure
TL;DR: Compound morulae produced in IVPS culture medium possessed the greatest deviations in cellular ultrastructure, compared with those produced in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Does in vitro culture affect the expression of insulin-like growth factor-II (IGF-II) messenger RNA in fetal bovine liver?

Biology of Reproduction, 60(1999), 248–249.

By: P. Blondin, P. Farin, A. Crosier, J. Alexander & C. Farin

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Effect of estrus synchronization with norgestomet on the integrity of oocytes from persistent follicles in beef cattle

Journal of Animal Science, 77(10), 2742–2748.

By: K. Borchert n, C. Farin n & S. Washburn n

MeSH headings : Animals; Cattle; Estradiol / blood; Estrus Synchronization; Female; Fertilization in Vitro / drug effects; Fertilization in Vitro / veterinary; Oocytes / drug effects; Ovarian Follicle / drug effects; Pregnenediones / pharmacology; Tissue and Organ Harvesting / veterinary
TL;DR: Oocyte quality and in vitro developmental competence were not compromised for oocytes from induced persistent follicles compared with oocyte from normal preovulatory follicles, and increased expansion of cumulus cells associated withOocytes from progestogen-induced persistent follicle may be relevant to the reduction of in vivo fertility associated with such follicles. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Gonadotropin-induced germinal vesicle breakdown in the mouse requires gene transcription.

Biology of Reproduction, 60(1999), 214.

By: K. Rodriguez, R. Petters & C. Farin

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Insulin-like growth factor (IGF)-I, ICF-I receptor, and IGF binding protein-3 messenger ribonucleic acids and protein in corpora lutea from prostaglandin F-2 alpha-treated gilts

BIOLOGY OF REPRODUCTION, 61(6), 1527–1534.

By: W. Nicholson, Z. Ge*, D. Plotner*, C. Farin n & J. Gadsby* 

MeSH headings : Animals; Blotting, Northern; Blotting, Western; Corpus Luteum / anatomy & histology; Corpus Luteum / drug effects; Corpus Luteum / metabolism; Dinoprost / pharmacology; Female; Insulin-Like Growth Factor Binding Protein 2 / metabolism; Insulin-Like Growth Factor Binding Protein 3 / genetics; Insulin-Like Growth Factor Binding Protein 3 / metabolism; Insulin-Like Growth Factor Binding Proteins / analysis; Insulin-Like Growth Factor I / analysis; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Organ Size; Progesterone / metabolism; RNA, Messenger / metabolism; Receptor, IGF Type 1 / genetics; Receptor, IGF Type 1 / metabolism; Swine / metabolism
TL;DR: PGF(2alpha)-induced premature luteolysis was associated with an increase in steady-state levels of IGF-IR mRNA, but it did not appear to be linked to changes in mRNA levels for IGF-I or IGFBP-3. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

A comparison of Menezo's B2 and tissue culture medium-199 for in vitro production of bovine blastocysts

THERIOGENOLOGY, 48(5), 699–709.

By: C. Farin n, J. Hasler, N. Martus n & J. Stokes

author keywords: cattle; embryo culture; in vitro fertilization; blastocyst; cell number
TL;DR: B2 medium was superior to M-199 medium when used in a co-culture system with BRL cells for the production of bovine blastocysts and there was no effect of type of medium on the distribution of embryo quality grades on any day examined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Determination of concentration of albendazole sulfoxide in plasma and uterine fluid of heifers

American Journal of Veterinary Research, 58(1), 62–65.

By: S. Piscopo, C. Farin & S. Bai

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

INHIBITION OF GERMINAL VESICLE BREAKDOWN IN BOVINE OOCYTES BY 5,6-DICHLORO-1-BETA-D-RIBOFURANOSYLBENZIMIDAZOLE (DRB)

MOLECULAR REPRODUCTION AND DEVELOPMENT, 37(3), 284–292.

By: C. Farin n & L. Yang  n

author keywords: CUMULUS CELLS; MEIOSIS; GVBD; COW; MESSENGER-RNA; ADENOSINE
MeSH headings : Animals; Cattle; Dichlororibofuranosylbenzimidazole / pharmacology; Female; Follicle Stimulating Hormone / pharmacology; In Vitro Techniques; Kinetics; Luteinizing Hormone / pharmacology; Meiosis / drug effects; Oocytes / drug effects; Oocytes / growth & development; Oocytes / metabolism; RNA Polymerase II / antagonists & inhibitors; RNA, Messenger / biosynthesis; Transcription, Genetic / drug effects; Uridine / metabolism
TL;DR: The hypothesis that gene transcription is required for the stimulatory phase of gonadotropin‐mediated GVBD in cultured bovine COC in a specific and reversible manner is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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