Cypress Perkins

Works (4)

Updated: March 6th, 2026 15:22

2025 article

Clostridioides difficile toxins alter host metabolic pathway and bile acid homeostasis gene expression in colonic epithelium

Thomas, S. A., Pike, C. M., Perkins, C. E., Brown, S. T., Jaen, X. M. E., McMillan, A. S., & Theriot, C. M. (2025, June 30). Infection and Immunity.

By: S. Thomas  n, C. Pike*, C. Perkins n, S. Brown n, X. Jaen n, A. McMillan  n, C. Theriot n

author keywords: toxins; <italic>C. difficile</italic>; Caco-2 cells; bile acid; cholesterol
topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Gastrointestinal motility and disorders; Gut microbiota and health; Pharmacological Effects of Natural Compounds
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: July 21, 2025

2025 article

Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family

Mons, E., Henderickx, J. G. E., Sanders, I. M. J. G., Rader, A. G., Perkins, C. E., Stel, F. M., … Martin, N. I. (2025, October 10). Nature Communications.

By: E. Mons *, J. Henderickx *, I. Sanders*, A. Rader *, C. Perkins n, F. Stel *, E. Groesen *, W. Smits *, C. Theriot n, N. Martin *

MeSH headings : Animals; Clostridioides difficile / drug effects; Clostridium Infections / prevention & control; Clostridium Infections / microbiology; Clostridium Infections / drug therapy; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Mice; Male; Glycopeptides / pharmacology; Glycopeptides / therapeutic use; Gastrointestinal Microbiome / drug effects; Vancomycin / pharmacology; Vancomycin / therapeutic use; Microbial Sensitivity Tests; Humans; Disease Models, Animal; Recurrence; Mice, Inbred C57BL
topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Gut microbiota and health; Microscopic Colitis
Source: NC State University Libraries
Added: March 4, 2026

2025 article

Structure-guided design of a synthetic bile acid that inhibits Clostridioides difficile TcdB toxin

Miletic, S., Icho, S., Li, Z., Tam, J., Rose, E. C., Perkins, C. E., … Melnyk, R. A. (2025, November 18). Nature Microbiology.

By: S. Miletic *, S. Icho*, Z. Li *, J. Tam *, E. Rose n, C. Perkins n, A. Nakhi *, X. Yang * ...

topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Bacillus and Francisella bacterial research; Antimicrobial Resistance in Staphylococcus
Source: NC State University Libraries
Added: November 19, 2025

2023 article

Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Foley, M. H., Walker, M. E., Stewart, A. K., Sarah, O. F., Gentry, E. C., Patel, S., … Theriot, C. M. (2023, March 13). Nature Microbiology, Vol. 3.

By: M. Foley n, M. Walker *, A. Stewart n, O. Sarah n, E. Gentry *, S. Patel *, V. Beaty *, G. Allen n ...

MeSH headings : Animals; Mice; Humans; Clostridioides difficile; Clostridioides; Bile Acids and Salts; Amidohydrolases; Clostridium Infections
topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Gut microbiota and health; Helicobacter pylori-related gastroenterology studies
TL;DR: Insight is provided into the structural basis of BSH mechanisms that shape the BA landscape and promote colonization resistance against C. difficile in vitro and in pre-clinical in vivo models of CDI. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.