Works (57)

2020 article

Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease

NEUROPSYCHOPHARMACOLOGY.

By: J. Hollander, D. Cory-Slechta, F. Jacka, S. Szabo, T. Guilarte, S. Bilbo, C. Mattingly, S. Moy ...

Sources: Web Of Science, ORCID
Added: March 30, 2020

2019 journal article

The Comparative Toxicogenomics Database: update 2019

NUCLEIC ACIDS RESEARCH, 47(D1), D948–D954.

By: A. Davis, C. Grondin, R. Johnson, D. Sciaky, R. McMorran, J. Wiegers, T. Wiegers, C. Mattingly

Sources: Web Of Science, ORCID
Added: April 9, 2019

2018 journal article

Accessing an expanded exposure science module at the comparative toxicogenomics database

Environmental Health Perspectives, 126(1).

By: C. Grondin, A. Davis, T. Wiegers, J. Wiegers & C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2018 journal article

Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study

International Journal of Obesity, 42(7), 1285–1295.

By: A. Green, C. Hoyo, C. Mattingly, Y. Luo, J. Tzeng, S. Murphy, D. Buchwalter, A. Planchart

Sources: Crossref, ORCID
Added: August 7, 2019

2018 journal article

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways

TOXICOLOGICAL SCIENCES, 165(1), 145–156.

By: A. Davis, T. Wiegers, J. Wiegers, R. Johnson, D. Sciaky, C. Grondin, C. Mattingly

Sources: NC State University Libraries, ORCID
Added: October 16, 2018

2018 journal article

Heavy Metal Exposure and Metabolic Syndrome: Evidence from Human and Model System Studies

Current Environmental Health Reports, 5(1), 110–124.

By: A. Planchart, A. Green, C. Hoyo & C. Mattingly

Sources: Crossref, ORCID
Added: August 7, 2019

2017 article

Applying evolutionary genetics to developmental toxicology and risk assessment

Reproductive Toxicology (Elmsford, N.Y.), Vol. 69, pp. 174–186.

By: M. Leung, A. Procter, J. Goldstone, J. Foox, R. DeSalle, C. Mattingly, M. Siddall, A. Timme-Laragy

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes

Toxicological Sciences, 155(2), 485–496.

By: A. Watson, A. Planchart, C. Mattingly, C. Winkler, D. Reif & S. Kullman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Informatics and data analytics to support exposome-based discovery for public health

Annual Review of Public Health, Vol 38, 38, 279–294.

By: A. Manrai, Y. Cui, P. Bushel, M. Hall, S. Karakitsios, C. Mattingly, M. Ritchie, C. Schmitt ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

The Comparative Toxicogenomics Database: update 2017

Nucleic Acids Research, 45(D1), D972–978.

By: A. Davis, C. Grondin, R. Johnson, D. Sciaky, B. King, R. McMorran, J. Wiegers, T. Wiegers, C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Advancing exposure science through chemical data curation and integration in the comparative toxicogenomics database

Environmental Health Perspectives, 124(10), 1592–1599.

By: C. Grondin, A. Davis, T. Wiegers, B. King, J. Wiegers, D. Reif, J. Hoppin, C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Advancing toxicology research using in vivo high throughput toxicology with small fish models

Altex-Alternatives to Animal Experimentation, 33(4), 435–452.

By: A. Planchart, C. Mattingly, D. Allen, P. Ceger, W. Casey, D. Hinton, J. Kanungo, S. Kullman ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Assessing the state of the art in biomedical relation extraction: Overview of the BioCreative V chemical-disease relation (CDR) task

Database-The Journal of Biological Databases and Curation.

By: C. Wei, Y. Peng, R. Leaman, A. Davis, C. Mattingly, J. Li, T. Wiegers, Z. Lu

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

BioCreative V CDR task corpus: A resource for chemical disease relation extraction

Database-The Journal of Biological Databases and Curation.

By: J. Li, Y. Sun, R. Johnson, D. Sciaky, C. Wei, R. Leaman, A. Davis, C. Mattingly ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Generating gene ontology-disease inferences to explore mechanisms of human disease at the comparative toxicogenomics database

PLoS One, 11(5).

By: A. Davis, T. Wiegers, B. King, J. Wiegers, C. Grondin, D. Sciaky, R. Johnson, C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 article

Laying a community-based foundation for data-driven semantic standards in environmental health sciences

Environmental Health Perspectives, Vol. 124, pp. 1136–1140.

By: C. Mattingly, R. Boyles, C. Lawler, A. Haugen, A. Dearry & M. Haendel

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

ToxEvaluator: An integrated computational platform to aid the interpretation of toxicology study-related findings

Database-The Journal of Biological Databases and Curation.

By: D. Pelletier, T. Wiegers, A. Enayetallah, C. Kibbey, M. Gosink, P. Koza-Taylor, C. Mattingly, M. Lawton

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 conference paper

Integrating literature-based curated data to predict mechanisms of toxicity

Presented at the OpenTox USA 2015, Baltimore, MD.

By: C. Mattingly

Event: OpenTox USA 2015 at Baltimore, MD on February 10-12, 2015

Source: NC State University Libraries
Added: August 10, 2019

2015 journal article

The Comparative Toxicogenomics Database's 10th year anniversary: Update 2015

Nucleic Acids Research, 43(D1), D914–920.

By: A. Davis, C. Grondin, K. Lennon-Hopkins, C. Saraceni-Richards, D. Sciaky, B. King, T. Wiegers, C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

BioC interoperability track overview

Database-The Journal of Biological Databases and Curation.

By: D. Comeau, R. Batista-Navarro, H. Dai, R. Dogan, A. Yepes, R. Khare, Z. Lu, H. Marques ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Web services-based text-mining demonstrates broad impacts for interoperability and process simplification

Database-The Journal of Biological Databases and Curation.

By: T. Wiegers, A. Davis & C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

- Text mining effectively scores and ranks the literature for improving chemical-gene-disease curation at the comparative toxicogenomics database

PLoS One, 8(4).

By: A. Davis, T. Wiegers, R. Johnson, J. Lay, K. Lennon-Hopkins, C. Saraceni-Richards, D. Sciaky, C. Murphy, C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

A CTD-Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug-disease and drug-phenotype interactions

Database-The Journal of Biological Databases and Curation.

By: A. Davis, T. Wiegers, P. Roberts, B. King, J. Lay, K. Lennon-Hopkins, D. Sciaky, R. Johnson ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Aquatic models, genomics and chemical risk management

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 155(1), 169–173.

By: K. Cheng, D. Hinton, C. Mattingly & A. Planchart

Sources: Crossref, ORCID
Added: August 7, 2019

2012 journal article

BioCreative-2012 virtual issue

Database-The Journal of Biological Databases and Curation.

By: C. Wu, C. Arighi, K. Cohen, L. Hirschman, M. Krallinger, Z. Lu, C. Mattingly, A. Valencia ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Collaborative biocuration--text-mining development task for document prioritization for curation

Database, 2012(0), bas037–bas037.

By: T. Wiegers, A. Davis & C. Mattingly

Sources: Crossref, ORCID
Added: August 7, 2019

2012 journal article

Computation of neutron multiplicity statistics using deterministic transport

IEEE Transactions on Nuclear Science, 59(2), 314–322.

By: J. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Disease model curation improvements at Mouse Genome Informatics

Database, 2012(0), bar063–bar063.

By: S. Bello, J. Richardson, A. Davis, T. Wiegers, C. Mattingly, M. Dolan, C. Smith, J. Blake, J. Eppig

Sources: Crossref, ORCID
Added: August 7, 2019

2012 journal article

MEDIC: a practical disease vocabulary used at the Comparative Toxicogenomics Database

Database, 2012(0), bar065–bar065.

By: A. Davis, T. Wiegers, M. Rosenstein & C. Mattingly

Sources: Crossref, ORCID
Added: August 7, 2019

2012 journal article

Providing the missing link: The exposure science ontology ExO

Environmental Science & Technology, 46(6), 3046–3053.

By: C. Mattingly, T. McKone, M. Callahan, J. Blake & E. Hubal

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Ranking transitive chemical-disease inferences using local network topology in the comparative toxicogenomics database

PLoS One, 7(11).

By: B. King, A. Davis, M. Rosenstein, T. Wiegers & C. Mattingly

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Targeted journal curation as a method to improve data currency at the Comparative Toxicogenomics Database

Database-The Journal of Biological Databases and Curation.

By: A. Davis, R. Johnson, K. Lennon-Hopkins, D. Sciaky, M. Rosenstein, T. Wiegers, C. Mattingly

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

The Comparative Toxicogenomics Database: update 2013

Nucleic Acids Research, 41(D1), D1104–D1114.

By: A. Davis, C. Murphy, R. Johnson, J. Lay, K. Lennon-Hopkins, C. Saraceni-Richards, D. Sciaky, B. King ...

Sources: Crossref, ORCID
Added: August 7, 2019

2011 journal article

DiseaseComps: a metric that discovers similar diseases based upon common toxicogenomic profiles at CTD

Bioinformation, 7(4), 154–156.

By: A. Davis, M. Rosenstein, T. Wiegers & C. Mattingly

Sources: Crossref, ORCID
Added: August 7, 2019

2011 journal article

The curation paradigm and application tool used for manual curation of the scientific literature at the Comparative Toxicogenomics Database

Database, 2011(0), bar034–bar034.

By: A. Davis, T. Wiegers, C. Murphy & C. Mattingly

Sources: Crossref, ORCID
Added: August 7, 2019

2010 journal article

2,3,7,8-Tetrachlorodibenzo-p-dioxin Upregulates FoxQ1b in Zebrafish Jaw Primordium

Chemical Research in Toxicology, 23(3), 480–487.

By: A. Planchart & C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2010 journal article

The Comparative Toxicogenomics Database: update 2011

Nucleic Acids Research, 39(Database), D1067–D1072.

By: A. Davis, B. King, S. Mockus, C. Murphy, C. Saraceni-Richards, M. Rosenstein, T. Wiegers, C. Mattingly

Sources: Crossref, ORCID
Added: August 7, 2019

2010 chapter

Understanding environment-disease connections: An introduction to the comparative toxicogenomics database (ctd)

In Nature Pathway Interaction Database.

By: C. Mattingly

Source: NC State University Libraries
Added: August 10, 2019

2009 journal article

Chemical databases for environmental health and clinical research

Toxicology Letters, 186(1), 62–65.

By: C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2009 journal article

Comparative Toxicogenomics Database: a knowledgebase and discovery tool for chemical-gene-disease networks

Nucleic Acids Research, 37(Database), D786–D792.

By: A. Davis, C. Murphy, C. Saraceni-Richards, M. Rosenstein, T. Wiegers & C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2009 journal article

GeneComps and ChemComps: a new CTD metric to identify genes and chemicals with shared toxicogenomic profiles

Bioinformation, 4(4), 173–174.

By: A. Davis, C. Murphy, C. Saraceni-Richards, M. Rosenstein, T. Wiegers, T. Hampton, C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2009 journal article

Genetic and environmental pathways to complex diseases

BMC Systems Biology, 3(1), 46.

By: J. Gohlke, R. Thomas, Y. Zhang, M. Rosenstein, A. Davis, C. Murphy, K. Becker, C. Mattingly, C. Portier

Sources: Crossref, ORCID
Added: August 10, 2019

2009 journal article

Perturbation of Defense Pathways by Low-Dose Arsenic Exposure in Zebrafish Embryos

Environmental Health Perspectives, 117(6), 981–987.

By: C. Mattingly, T. Hampton, K. Brothers, N. Griffin & A. Planchart

Sources: Crossref, ORCID
Added: August 10, 2019

2009 journal article

Text mining and manual curation of chemical-gene-disease networks for the Comparative Toxicogenomics Database (CTD)

BMC Bioinformatics, 10(1).

By: T. Wiegers, A. Davis, K. Cohen, L. Hirschman & C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2008 journal article

An Evaluation of Information Content as a Metric for the Inference of Putative Conserved Noncoding Regions in DNA Sequences Using a Genetic Algorithms Approach

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 5(1), 1–14.

By: C. Bates Congdon, J. Aman, G. Nava, H. Gaskins & C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2008 journal article

The Comparative Toxicogenomics Database facilitates identification and understanding of chemical-gene-disease associations: arsenic as a case study

BMC Medical Genomics, 1(1).

By: A. Davis, C. Murphy, M. Rosenstein, T. Wiegers & C. Mattingly

Sources: Crossref, ORCID
Added: August 10, 2019

2007 conference paper

Towards Interactive Visualization for Exploring Conserved Motifs in Noncoding DNA Sequence

2007 Frontiers in the Convergence of Bioscience and Information Technologies. Presented at the 2007 Frontiers in the Convergence of Bioscience and Information Technologies.

By: C. Congdon, H. Gaskins, G. Nava & C. Mattingly

Event: 2007 Frontiers in the Convergence of Bioscience and Information Technologies

Sources: Crossref, ORCID
Added: August 10, 2019

2006 journal article

The Comparative Toxicogenomics Database (CTD): a resource for comparative toxicological studies

Journal of Experimental Zoology Part A: Comparative Experimental Biology, 305A(9), 689–692.

By: C. Mattingly, M. Rosenstein, G. Colby, J. Forrest Jr & J. Boyer

Sources: Crossref, ORCID
Added: August 10, 2019

2006 journal article

The Comparative Toxicogenomics Database: A Cross-Species Resource for Building Chemical-Gene Interaction Networks

Toxicological Sciences, 92(2), 587–595.

By: C. Mattingly, M. Rosenstein, A. Davis, G. Colby, J. Forrest & J. Boyer

Sources: Crossref, ORCID
Added: August 10, 2019

2005 conference paper

Preliminary Results for GAMI: A Genetic Algorithms Approach to Motif Inference

2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology. Presented at the 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology.

By: C. Congdon, C. Fizer, N. Smith, H. Gaskins, J. Aman, G. Nava, C. Mattingly

Event: 2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology

Sources: Crossref, ORCID
Added: August 10, 2019

2004 journal article

Cell and Molecular Biology of Marine Elasmobranchs: Squalus acanthias and Raja erinacea

Zebrafish, 1(2), 111–120.

By: C. Mattingly, A. Parton, L. Dowell, J. Rafferty & D. Barnes

Sources: Crossref, ORCID
Added: August 10, 2019

2004 journal article

Marine Organism Cell Biology and Regulatory Sequence Discoveryin Comparative Functional Genomics

Cytotechnology, 46(2-3), 123–137.

By: D. Barnes, C. Mattingly, A. Parton, L. Dowell, C. Bayne & J. Forrest

Sources: Crossref, ORCID
Added: August 10, 2019

2004 journal article

Promoting comparative molecular studies in environmental health research: an overview of the comparative toxicogenomics database (CTD)

The Pharmacogenomics Journal, 4(1), 5–8.

By: C. Mattingly, G. Colby, M. Rosenstein, J. Forrest & J. Boyer

Sources: Crossref, ORCID
Added: August 10, 2019

2003 journal article

The Comparative Toxicogenomics Database (CTD).

Environmental Health Perspectives, 111(6), 793–795.

By: C. Mattingly, G. Colby, J. Forrest & J. Boyer

Sources: Crossref, ORCID
Added: August 10, 2019

2001 journal article

Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio).

Environmental Health Perspectives, 109(8), 845–849.

By: C. Mattingly, J. McLachlan & W. Toscano

Sources: Crossref, ORCID
Added: August 10, 2019

2001 journal article

Posttranscriptional silencing of cytochrome P4501A1 (CYP1A1) during zebrafish (Danio rerio) development

Developmental Dynamics, 222(4), 645–654.

By: C. Mattingly & W. Toscano

Sources: Crossref, ORCID
Added: August 10, 2019

1999 journal article

Estrogen Receptor Reduces CYP1A1 Induction in Cultured Human Endometrial Cells

Journal of Biological Chemistry, 274(6), 3430–3438.

By: M. Ricci, D. Toscano, C. Mattingly & W. Toscano

Sources: Crossref, ORCID
Added: August 10, 2019

Employment

2019 - present

NC State University Raleigh, NC, US
Professor Biological Sciences

2018 - present

NC State University Raleigh, NC, US
Interim Head Biological Sciences

2012 - 2019

NC State University Raleigh, NC, US
Associate Professor Biological Sciences