Clement Kleinstreuer

Sridhar, K., Chari, S., & Kleinstreuer, C. (2023, March 16). A computational study of droplet-spray formation from pressurized metered dose inhalers with applications to drug deposition in a human lung-airway model. AEROSOL SCIENCE AND TECHNOLOGY. https://doi.org/10.1080/02786826.2023.2189927

Dave, S., Kleinstreuer, C., & Chari, S. (2022). An effective PBPK model predicting dissolved drug transfer from a representative nasal cavity to the blood stream. JOURNAL OF AEROSOL SCIENCE, 160. https://doi.org/10.1016/j.jaerosci.2021.105898

Gurumurthy, A., & Kleinstreuer, C. (2022). Analysis of improved oral drug delivery with different helical stream inhalation modes. COMPUTERS IN BIOLOGY AND MEDICINE, 141. https://doi.org/10.1016/j.compbiomed.2021.105132

Chari, S., Sridhar, K., & Kleinstreuer, C. (2022). Effects of subject-variability on nasally inhaled drug deposition, uptake, and clearance. JOURNAL OF AEROSOL SCIENCE, 165. https://doi.org/10.1016/j.jaerosci.2022.106021

Vachhani, S., & Kleinstreuer, C. (2021). Comparison of micron- and nano-particle transport in the human nasal cavity with a focus on the olfactory region. COMPUTERS IN BIOLOGY AND MEDICINE, 128. https://doi.org/10.1016/j.compbiomed.2020.104103

Chari, S., Sridhar, K., Walenga, R., & Kleinstreuer, C. (2021). Computational analysis of a 3D mucociliary clearance model predicting nasal drug uptake. JOURNAL OF AEROSOL SCIENCE, 155. https://doi.org/10.1016/j.jaerosci.2021.105757

Kleinstreuer, C. (2021). Essentials of Engineering Thermodynamics: Principles and Applications. New York: McGraw-Hill Education.

Gurumurthy, A., & Kleinstreuer, C. (2021). Helical fluid-particle flow dynamics for controlling micron-particle deposition in a representative human upper lung-airway model. JOURNAL OF AEROSOL SCIENCE, 151. https://doi.org/10.1016/j.jaerosci.2020.105656

Gurumurthy, A., & Kleinstreuer, C. (2021). Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 143(11). https://doi.org/10.1115/1.4051217

Vachhani, S., & Kleinstreuer, C. (2021, July 24). Numerical analysis of enhanced nano-drug delivery to the olfactory bulb. AEROSOL SCIENCE AND TECHNOLOGY. https://doi.org/10.1080/02786826.2021.1959018

Kulkarni, N. A., & Kleinstreuer, C. (2020). High-temperature effects on the mucus layers in a realistic human upper airway model. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 163. https://doi.org/10.1016/j.ijheatmasstransfer.2020.120467

Saini, N., & Kleinstreuer, C. (2019). A new collision model for ellipsoidal particles in shear flow. JOURNAL OF COMPUTATIONAL PHYSICS, 376, 1028–1050. https://doi.org/10.1016/j.jcp.2018.09.039

Xu, Z., & Kleinstreuer, C. (2019). Heterogeneous blood flow in microvessels with applications to nanodrug transport and mass transfer into tumor tissue. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 18(1), 99–110. https://doi.org/10.1007/s10237-018-1071-2

Kolanjiyil, A. V., Kleinstreuer, C., Kleinstreuer, N. C., Pham, W., & Sadikot, R. T. (2019). Mice-to-men comparison of inhaled drug-aerosol deposition and clearance. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 260, 82–94. https://doi.org/10.1016/j.resp.2018.11.003

Kolanjiyil, A. V., & Kleinstreuer, C. (2019). Modeling Airflow and Particle Deposition in a Human Acinar Region. COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE, 2019. https://doi.org/10.1155/2019/5952941

Mahian, O., Kolsi, L., Amani, M., Estelle, P., Ahmadi, G., Kleinstreuer, C., … Pop, L. (2019). [Review of Recent advances in modeling and simulation of nanofluid flows-Part I: Fundamentals and theory]. PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS, 790, 1–48. https://doi.org/10.1016/j.physrep.2018.11.004

Mahian, O., Kolsi, L., Amani, M., Estelle, P., Ahmadi, G., Kleinstreuer, C., … Pop, I. (2019). [Review of Recent advances in modeling and simulation of nanofluid flows-Part II: Applications]. PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS, 791, 1–59. https://doi.org/10.1016/j.physrep.2018.11.003

Feng, Y., Zhao, J., Kleinstreuer, C., Wang, Q., Wang, J., Wu, D. H., & Lin, J. (2018). An in silico inter-subject variability study of extra-thoracic morphology effects on inhaled particle transport and deposition. JOURNAL OF AEROSOL SCIENCE, 123, 185–207. https://doi.org/10.1016/j.jaerosci.2018.05.010

Chari, S., & Kleinstreuer, C. (2018). Convective mass and heat transfer enhancement of nanofluid streams in bifurcating microchannels. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 125, 1212–1229. https://doi.org/10.1016/j.ijheatmasstransfer.2018.04.075

Xu, Z., & Kleinstreuer, C. (2018). Direct nanodrug delivery for tumor targeting subject to shear-augmented diffusion in blood flow. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 56(11), 1949–1958. https://doi.org/10.1007/s11517-018-1818-z

Chen, X., Kleinstreuer, C., Zhong, W., Feng, Y., & Zhou, X. (2018). Effects of thermal airflow and mucus-layer interaction on hygroscopic droplet deposition in a simple mouth–throat model. Aerosol Science and Technology, 52(8), 900–912. https://doi.org/10.1080/02786826.2018.1476751

Clement, K. (2018). Modern Fluid Dynamics. https://doi.org/10.1201/b22066

Calmet, H., Kleinstreuer, C., Houzeaux, G., Kolanjiyil, A. V., Lehmkuhl, O., Olivares, E., & Vazquez, M. (2018). Subject-variability effects on micron particle deposition in human nasal cavities. JOURNAL OF AEROSOL SCIENCE, 115, 12–28. https://doi.org/10.1016/j.jaerosci.2017.10.008

Kolanjiyil, A. V., & Kleinstreuer, C. (2017). Computational analysis of aerosol-dynamics in a human whole-lung airway model. JOURNAL OF AEROSOL SCIENCE, 114, 301–316. https://doi.org/10.1016/j.jaerosci.2017.10.001

Kolanjiyil, A. V., Kleinstreuer, C., & Sadikot, R. T. (2017). Computationally efficient analysis of particle transport and deposition in a human whole-lung-airway model. Part II: Dry powder inhaler application. Computers in Biology and Medicine, 84, 247–253. https://doi.org/10.1016/J.COMPBIOMED.2016.10.025

Chen, X., Feng, Y., Zhong, W., & Kleinstreuer, C. (2017). Numerical investigation of the interaction, transport and deposition of multicomponent droplets in a simple mouth-throat model. JOURNAL OF AEROSOL SCIENCE, 105, 108–127. https://doi.org/10.1016/j.jaerosci.2016.12.001

Feng, Y., Kleinstreuer, C., Castro, N., & Rostami, A. (2016). Computational transport, phase change and deposition analysis of inhaled multicomponent droplet-vapor mixtures in an idealized human upper lung model. JOURNAL OF AEROSOL SCIENCE, 96, 96–123. https://doi.org/10.1016/j.jaerosci.2016.03.001

Kolanjiyil, A. V., & Kleinstreuer, C. (2016). Computationally efficient analysis of particle transport and deposition in a human whole-lung-airway model. Part I: Theory and model validation. COMPUTERS IN BIOLOGY AND MEDICINE, 79, 193–204. https://doi.org/10.1016/j.compbiomed.2016.10.020

Chen, X., Zhong, W., Tom, J., Kleinstreuer, C., Feng, Y., & He, X. (2016). Experimental-computational study of fibrous particle transport and deposition in a bifurcating lung model. PARTICUOLOGY, 28, 102–113. https://doi.org/10.1016/j.partic.2016.02.002

Vaish, M., Kleinstreuer, C., Kolanjiyil, A. V., Saini, N., & Pillalamarri, N. R. (2016). Laminar/turbulent airflow and microsphere deposition in a patient-specific airway geometry using an open-source solver. INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING AND TECHNOLOGY, 22(2), 145–161. https://doi.org/10.1504/ijbet.2016.079145

Xu, Z., Jernigan, S., Kleinstreuer, C., & Buckner, G. D. (2016). Solid Tumor Embolotherapy in Hepatic Arteries with an Anti-reflux Catheter System. ANNALS OF BIOMEDICAL ENGINEERING, 44(4), 1036–1046. https://doi.org/10.1007/s10439-015-1411-7

Vaish, M., & Kleinstreuer, C. (2015). A Lagrangian Approach for Calculating Microsphere Deposition in a One-Dimensional Lung-Airway Model. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 137(9). https://doi.org/10.1115/1.4030977

Umbarkar, T. S., & Kleinstreuer, C. (2015). Computationally Efficient Fluid-Particle Dynamics Simulations of Arterial Systems. COMMUNICATIONS IN COMPUTATIONAL PHYSICS, 17(2), 401–423. https://doi.org/10.4208/cicp.160114.120914a

Feng, Y., Kleinstreuer, C., & Rostami, A. (2015). Evaporation and condensation of multicomponent electronic cigarette droplets and conventional cigarette smoke particles in an idealized G3-G6 triple bifurcating unit. JOURNAL OF AEROSOL SCIENCE, 80, 58–74. https://doi.org/10.1016/j.jaerosci.2014.11.002

Childress, E. M., & Kleinstreuer, C. (2014). Computationally Efficient Particle Release Map Determination for Direct Tumor-Targeting in a Representative Hepatic Artery System. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 136(1). https://doi.org/10.1115/1.4025881

Xu, Z., & Kleinstreuer, C. (2014). Concentration photovoltaic-thermal energy co-generation system using nanofluids for cooling and heating. ENERGY CONVERSION AND MANAGEMENT, 87, 504–512. https://doi.org/10.1016/j.enconman.2014.07.047

Feng, Y., & Kleinstreuer, C. (2014). DDPM-DEM simulations of particulate flows in human tracheobronchial airways. Proceedings of the ASME International Mechanical Engineering Congress and Exposition, 2013, vol 3B. https://doi.org/10.1115/imece2013-62307

Childress, E. M., & Kleinstreuer, C. (2014). Impact of Fluid-Structure Interaction on Direct Tumor-Targeting in a Representative Hepatic Artery System. ANNALS OF BIOMEDICAL ENGINEERING, 42(3), 461–474. https://doi.org/10.1007/s10439-013-0910-7

Feng, Y., & Kleinstreuer, C. (2014). Micron-particle transport, interactions and deposition in triple lung-airway bifurcations using a novel modeling approach. JOURNAL OF AEROSOL SCIENCE, 71, 1–15. https://doi.org/10.1016/j.jaerosci.2014.01.003

Mahian, O., Kianifar, A., Kleinstreuer, C., Al-Nimr, M. A., Pop, I., Sahin, A. Z., & Wongwises, S. (2013). [Review of A review of entropy generation in nanofluid flow]. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 65, 514–532. https://doi.org/10.1016/j.ijheatmasstransfer.2013.06.010

Feng, Y., & Kleinstreuer, C. (2013). Analysis of non-spherical particle transport in complex internal shear flows. PHYSICS OF FLUIDS, 25(9). https://doi.org/10.1063/1.4821812

Kleinstreuer, C., & Feng, Y. (2013). [Review of Computational Analysis of Non-Spherical Particle Transport and Deposition in Shear Flow With Application to Lung Aerosol Dynamics-A Review]. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 135(2). https://doi.org/10.1115/1.4023236

Han, K., Lee, W.-H., Kleinstreuer, C., & Koo, J. (2013). Critical Invalidation of Temperature Dependence of Nanofluid Thermal Conductivity Enhancement. JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, 135(5). https://doi.org/10.1115/1.4023544

Kleinstreuer, C., & Feng, Y. (2013). [Review of Lung Deposition Analyses of Inhaled Toxic Aerosols in Conventional and Less Harmful Cigarette Smoke: A Review]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 10(9), 4454–4485. https://doi.org/10.3390/ijerph10094454

Kolanjiyil, A. V., & Kleinstreuer, C. (2013). Nanoparticle Mass Transfer From Lung Airways to Systemic Regions-Part I: Whole-Lung Aerosol Dynamics. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 135(12). https://doi.org/10.1115/1.4025332

Kolanjiyil, A. V., & Kleinstreuer, C. (2013). Nanoparticle Mass Transfer From Lung Airways to Systemic Regions-Part II: Multi-Compartmental Modeling. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 135(12). https://doi.org/10.1115/1.4025333

Richards, A. L., Kleinstreuer, C., Kennedy, A. S., Childress, E., & Buckner, G. D. (2012). Experimental Microsphere Targeting in a Representative Hepatic Artery System. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 59(1), 198–204. https://doi.org/10.1109/tbme.2011.2170195

Zhang, Z., Kleinstreuer, C., & Hyun, S. (2012). Size-change and deposition of conventional and composite cigarette smoke particles during inhalation in a subject-specific airway model. JOURNAL OF AEROSOL SCIENCE, 46, 34–52. https://doi.org/10.1016/j.jaerosci.2011.12.002

Feng, Y., & Kleinstreuer, C. (2012, May). Thermal Nanofluid Property Model With Application to Nanofluid Flow in a Parallel Disk System-Part II: Nanofluid Flow Between Parallel Disks. JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, Vol. 134. https://doi.org/10.1115/1.4005633

Kleinstreuer, C., & Feng, Y. (2012, May). Thermal Nanofluid Property Model With Application to Nanofluid Flow in a Parallel-Disk System-Part I: A New Thermal Conductivity Model for Nanofluid Flow. JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, Vol. 134. https://doi.org/10.1115/1.4005632

Zhang, Z., Kleinstreuer, C., & Feng, Y. (2012). Vapor deposition during cigarette smoke inhalation in a subject-specific human airway model. JOURNAL OF AEROSOL SCIENCE, 53, 40–60. https://doi.org/10.1016/j.jaerosci.2012.05.008

Basciano, C., Kleinstreuer, C., Hyun, S., & Finol, E. A. (2011). A Relation Between Near-Wall Particle-Hemodynamics and Onset of Thrombus Formation in Abdominal Aortic Aneurysms. ANNALS OF BIOMEDICAL ENGINEERING, 39(7), 2010–2026. https://doi.org/10.1007/s10439-011-0285-6

Li, Z., & Kleinstreuer, C. (2011). Airflow analysis in the alveolar region using the lattice-Boltzmann method. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 49(4), 441–451. https://doi.org/10.1007/s11517-011-0743-1

Li, J., Sheeran, P. S., & Kleinstreuer, C. (2011). Analysis of Multi-Layer Immiscible Fluid Flow in a Microchannel. JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, 133(11). https://doi.org/10.1115/1.4005134

Zhang, Z., & Kleinstreuer, C. (2011). Computational analysis of airflow and nanoparticle deposition in a combined nasal-oral-tracheobronchial airway model. JOURNAL OF AEROSOL SCIENCE, 42(3), 174–194. https://doi.org/10.1016/j.jaerosci.2011.01.001

Zhang, Z., & Kleinstreuer, C. (2011). Deposition of naphthalene and tetradecane vapors in models of the human respiratory system. INHALATION TOXICOLOGY, 23(1), 44–57. https://doi.org/10.3109/08958378.2010.540261

Kleinstreuer, C., & Feng, Y. (2011). [Review of Experimental and theoretical studies of nanofluid thermal conductivity enhancement: a review]. NANOSCALE RESEARCH LETTERS, 6. https://doi.org/10.1186/1556-276x-6-229

Hong, S. W., Kang, Y.-T., Kleinstreuer, C., & Koo, J. (2011). Impact analysis of natural convection on thermal conductivity measurements of nanofluids using the transient hot-wire method. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 54(15-16), 3448–3456. https://doi.org/10.1016/j.ijheatmasstransfer.2011.03.041

Zhang, Z., & Kleinstreuer, C. (2011). Laminar-to-turbulent fluid-nanoparticle dynamics simulations: Model comparisons and nanoparticle-deposition applications. International Journal for Numerical Methods in Biomedical Engineering, 27(12), 1930–1950. https://doi.org/10.1002/cnm.1447

Kleinstreuer, C., & Zhang, Z. (2011). Optimal Drug-Aerosol Delivery to Predetermined Lung Sites. JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, 133(1). https://doi.org/10.1115/1.4002224

Kleinstreuer, C., & Zhang, Z. (2010). Airflow and Particle Transport in the Human Respiratory System. ANNUAL REVIEW OF FLUID MECHANICS, Vol. 42, pp. 301–334. https://doi.org/10.1146/annurev-fluid-121108-145453

Kennedy, A. S., Kleinstreuer, C., Basciano, C. A., & Dezarn, W. A. (2010). COMPUTER MODELING OF YTTRIUM-90-MICROSPHERE TRANSPORT IN THE HEPATIC ARTERIAL TREE TO IMPROVE CLINICAL OUTCOMES. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 76(2), 631–637. https://doi.org/10.1016/j.ijrobp.2009.06.069

Basciano, C. A., Kleinstreuer, C., Kennedy, A. S., Dezarn, W. A., & Childress, E. (2010). Computer Modeling of Controlled Microsphere Release and Targeting in a Representative Hepatic Artery System. ANNALS OF BIOMEDICAL ENGINEERING, 38(5), 1862–1879. https://doi.org/10.1007/s10439-010-9955-z

Shenoy, A. R., & Kleinstreuer, C. (2010). Influence of aspect ratio on the dynamics of a freely moving circular disk. JOURNAL OF FLUID MECHANICS, 653, 463–487. https://doi.org/10.1017/s0022112010000418

Feng, Y., & Kleinstreuer, C. (2010). Nanofluid convective heat transfer in a parallel-disk system. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 53(21-22), 4619–4628. https://doi.org/10.1016/j.ijheatmasstransfer.2010.06.031

Kleinstreuer, C., & Zhang, Z. (2009). An Adjustable Triple-Bifurcation Unit Model for Air-Particle Flow Simulations in Human Tracheobronchial Airways. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 131(2). https://doi.org/10.1115/1.3005339

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2009). Comparison of analytical and CFD models with regard to micron particle deposition in a human 16-generation tracheobronchial airway model. JOURNAL OF AEROSOL SCIENCE, 40(1), 16–28. https://doi.org/10.1016/j.jaerosci.2008.08.003

Basciano, C. A., & Kleinstreuer, C. (2009). Invariant-Based Anisotropic Constitutive Models of the Healthy and Aneurysmal Abdominal Aortic Wall. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 131(2). https://doi.org/10.1115/1.3005341

Li, J., & Kleinstreuer, C. (2009). Microfluidics analysis of nanoparticle mixing in a microchannel system. MICROFLUIDICS AND NANOFLUIDICS, 6(5), 661–668. https://doi.org/10.1007/s10404-008-0341-1

Kleinstreuer, C., Zhang, Z., Li, Z., Roberts, W. L., & Rojas, C. (2008). A new methodology for targeting drug-aerosols in the human respiratory system. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 51(23-24), 5578–5589. https://doi.org/10.1016/j.ijheatmasstransfer.2008.04.052

Koo, J., Kang, Y., & Kleinstreuer, C. (2008). A nonlinear effective thermal conductivity model for carbon nanotube and nanofiber suspensions. NANOTECHNOLOGY, 19(37). https://doi.org/10.1088/0957-4484/19/37/375705

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2008). Airflow and Nanoparticle Deposition in a 16-Generation Tracheobronchial Airway Model. ANNALS OF BIOMEDICAL ENGINEERING, 36(12), 2095–2110. https://doi.org/10.1007/s10439-008-9583-z

Kleinstreuer, C., Li, Z., Basciano, C. A., Seelecke, S., & Farber, M. A. (2008). Computational mechanics of Nitinol stent grafts. JOURNAL OF BIOMECHANICS, 41(11), 2370–2378. https://doi.org/10.1016/j.jbiomech.2008.05.032

Shi, H., Kleinstreuer, C., & Zhang, Z. (2008). Dilute suspension flow with nanoparticle deposition in a representative nasal airway model. PHYSICS OF FLUIDS, 20(1). https://doi.org/10.1063/1.2833468

Kleinstreuer, C., & Li, J. (2008, February). Discussion: "Effects of various parameters on nanotluid thermal conductivity" ( Jang, S.P., and Choi, S.D.S., 2007, ASME J. heat transfer, 129, pp. 617-623). JOURNAL OF HEAT TRANSFER-TRANSACTIONS OF THE ASME, Vol. 130. https://doi.org/10.1115/1.2812307

Shenoy, A. R., & Kleinstreuer, C. (2008). Flow over a thin circular disk at low to moderate Reynolds numbers. JOURNAL OF FLUID MECHANICS, 605, 253–262. https://doi.org/10.1017/S0022112008001626

Kleinstreuer, C., Li, J., & Koo, J. (2008). Microfluidics of nano-drug delivery. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 51(23-24), 5590–5597. https://doi.org/10.1016/j.ijheatmasstransfer.2008.04.043

Kleinstreuer, C., Zhang, Z., & Li, Z. (2008). [Review of Modeling airflow and particle transport/deposition in pulmonary airways]. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 163(1-3), 128–138. https://doi.org/10.1016/j.resp.2008.07.002

Kleinstreuer, C., Zhang, Z., & Donohue, J. F. (2008). Targeted drug-aerosol delivery in the human respiratory system. ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, Vol. 10, pp. 195–220. https://doi.org/10.1146/annurev.bioeng.10.061807.160544

Li, J., & Kleinstreuer, C. (2008). Thermal performance of nanofluid flow in microchannels. INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW, 29(4), 1221–1232. https://doi.org/10.1016/j.ijheatfluidflow.2008.01.005

Li, Z., & Kleinstreuer, C. (2007). A comparison between different asymmetric abdominal aortic aneurysm morphologies employing computational fluid-structure interaction analysis. EUROPEAN JOURNAL OF MECHANICS B-FLUIDS, 26(5), 615–631. https://doi.org/10.1016/j.euromechflu.2007.03.003

Kleinstreuer, C., Zhang, Z., & Kim, C. S. (2007). Combined inertial and gravitational deposition of microparticles in small model airways of a human respiratory system. JOURNAL OF AEROSOL SCIENCE, 38(10), 1047–1061. https://doi.org/10.1016/j.jaerosci.2007.08.010

Kleinstreuer, C., Shi, H., & Zhang, Z. (2007). Computational analyses of a pressurized metered dose inhaler and a new drug-aerosol targeting methodology. JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG, 20(3), 294–309. https://doi.org/10.1089/jam.2006.0617

Kleinstreuer, C., Li, Z., & Farber, M. A. (2007). [Review of Fluid-structure interaction analyses of stented abdominal aortic aneurysms]. Annual Review of Biomedical Engineering, 9, 169–204. https://doi.org/10.1146/annurev.bioeng.9.060906.151853

Shi, H., Kleinstreuer, C., & Zhang, Z. (2007). Modeling of inertial particle transport and deposition in human nasal cavities with wall roughness. JOURNAL OF AEROSOL SCIENCE, 38(4), 398–419. https://doi.org/10.1016/j.jaerosci.2007.02.002

Li, Z., Kleinstreuer, C., & Zhang, Z. (2007). Particle deposition in the human tracheobronchial airways due to transient inspiratory flow patterns. JOURNAL OF AEROSOL SCIENCE, 38(6), 625–644. https://doi.org/10.1016/j.jaerosci.2007.03.010

Shi, H., & Kleinstreuer, C. (2007). Simulation and analysis of high-speed droplet spray dynamics. JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, 129(5), 621–633. https://doi.org/10.1115/1.2717621

Li, Z., Kleinstreuer, C., & Zhang, Z. (2007). Simulation of airflow fields and microparticle deposition in realistic human lung airway models. Part I: Airflow patterns. EUROPEAN JOURNAL OF MECHANICS B-FLUIDS, 26(5), 632–649. https://doi.org/10.1016/j.euromechflu.2007.02.003

Li, Z., Kleinstreuer, C., & Zhang, Z. (2007). Simulation of airflow fields and microparticle deposition in realistic human lung airway models. Part II: Particle transport and deposition. EUROPEAN JOURNAL OF MECHANICS B-FLUIDS, 26(5), 650–668. https://doi.org/10.1016/j.euromechflu.2007.02.004

Li, Z., & Kleinstreuer, C. (2006). Analysis of biomechanical factors affecting stent-graft migration in an abdominal aortic aneurysm model. JOURNAL OF BIOMECHANICS, 39(12), 2264–2273. https://doi.org/10.1016/j.jbiomech.2005.07.010

Li, Z., & Kleinstreuer, C. (2006). Computational analysis of type II endoleaks in a stented abdominal aortic aneurysm model. JOURNAL OF BIOMECHANICS, 39(14), 2573–2582. https://doi.org/10.1016/j.jbiomech.2005.09.002

Li, Z., & Kleinstreuer, C. (2006). Effects of blood flow and vessel geometry on wall stress and rupture risk of abdominal aortic aneurysms. Journal of Medical Engineering & Technology, 30(5), 283–297. https://doi.org/10.1080/03091900500217406

Li, Z., & Kleinstreuer, C. (2006). Effects of major endoleaks on a stented abdominal aortic aneurysm. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 128(1), 59–68. https://doi.org/10.1115/1.2132376

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2006). Isotonic and hypertonic saline droplet deposition in a human upper airway model. JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG, 19(2), 184–198. https://doi.org/10.1089/jam.2006.19.184

Shi, H., Kleinstreuer, C., & Zhang, Z. (2006). Laminar airflow and nanoparticle or vapor deposition in a human nasal cavity model. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 128(5), 697–706. https://doi.org/10.1115/1.2244574

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2006). Transport and uptake of MTBE and ethanol vapors in a human upper airway model. INHALATION TOXICOLOGY, 18(3), 169–184. https://doi.org/10.1080/08958370500434172

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2006). Water vapor transport and its effects on the deposition of hygroscopic droplets in a human upper airway model. AEROSOL SCIENCE AND TECHNOLOGY, 40(1), 1–16. https://doi.org/10.1080/02786820500461154

Li, Z., & Kleinstreuer, C. (2005). A new wall stress equation for aneurysm-rupture prediction. ANNALS OF BIOMEDICAL ENGINEERING, 33(2), 209–213. https://doi.org/10.1007/s10439-005-8979-2

Koo, J., & Kleinstreuer, C. (2005). Analysis of surface roughness effects on heat transfer in micro-conduits. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 48(13), 2625–2634. https://doi.org/10.1016/j.ijheatmasstransfer.2005.01.024

Li, Z. H., & Kleinstreuer, C. (2005). Blood flow and structure interactions in a stented abdominal aortic aneurysm model. MEDICAL ENGINEERING & PHYSICS, 27(5), 369–382. https://doi.org/10.1016/j.medengphy.2004.12.003

Zhang, Z., Kleinstreuer, C., Donohue, J. F., & Kim, C. S. (2005). Comparison of micro- and nano-size particle depositions in a human upper airway model. JOURNAL OF AEROSOL SCIENCE, 36(2), 211–233. https://doi.org/10.1016/j.jaerosci.2004.08.006

Li, Z., Kleinstreuer, C., & Farber, M. (2005). Computational analysis of biomechanical contributors to endovascular graft failure. BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 4(4), 221–234. https://doi.org/10.1007/s10237-005-0003-0

Longest, P. W., & Kleinstreuer, C. (2005). Computational models for simulating multicomponent aerosol evaporation in the upper respiratory airways. AEROSOL SCIENCE AND TECHNOLOGY, 39(2), 124–138. https://doi.org/10.1080/027868290908786

Li, Z., & Kleinstreuer, C. (2005). Fluid-structure interaction effects on sac-blood pressure and wall stress in a stented aneurysm. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 127(4), 662–671. https://doi.org/10.1115/1.1934040

Koo, J. M., & Kleinstreuer, C. (2005). Laminar nanofluid flow in microheat-sinks. International Journal of Heat and Mass Transfer, 48(13), 2652–2661. https://doi.org/10.1016/j.ijheattransfer.2005.01.029

Longest, P. W., Kleinstreuer, C., & Deanda, A. (2005, December). Numerical simulation of wall shear stress and particle-based hemodynamic parameters in pre-cuffed and streamlined end-to-side anastomoses. ANNALS OF BIOMEDICAL ENGINEERING, Vol. 33, pp. 1752–1766. https://doi.org/10.1007/s10439-005-7784-2

Koo, J., & Kleinstreuer, C. (2004). A new thermal conductivity model for nanofluids. JOURNAL OF NANOPARTICLE RESEARCH, 6(6), 577–588. https://doi.org/10.1007/s11051-004-3170-5

Zhang, Z., & Kleinstreuer, C. (2004). Airflow structures and nano-particle deposition in a human upper airway model. JOURNAL OF COMPUTATIONAL PHYSICS, 198(1), 178–210. https://doi.org/10.1016/j.jcp.2003.11.034

Kleinstreuer, C., & Koo, J. (2004). Computational analysis of wall roughness effects for liquid flow in micro-conduits. Journal of Fluids Engineering, 126(1), 09-.

Longest, P. W., Kleinstreuer, C., & Buchanan, JR. (2004). Efficient computation of micro-particle dynamics including wall effects. COMPUTERS & FLUIDS, 33(4), 577–601. https://doi.org/10.1016/j.compfluid.2003.06.002

Longest, P. W., & Kleinstreuer, C. (2004). Interacting effects of uniform flow, plane shear, and near-wall proximity on the heat and mass transfer of respiratory aerosols. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 47(22), 4745–4759. https://doi.org/10.1016/j.ijheatmasstransfer.2004.05.029

Shi, H., Kleinstreuer, C., Zhang, Z., & Kim, C. S. (2004). Nanoparticle transport and deposition in bifurcating tubes with different inlet conditions. PHYSICS OF FLUIDS, 16(7), 2199–2213. https://doi.org/10.1063/1.1724830

Hyun, S., Kleinstreuer, C., Longest, P. W., & Chen, C. (2004). Particle-hemodynamics simulations and design options for surgical reconstruction of diseased carotid artery bifurcations. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 126(2), 188–195. https://doi.org/10.1115/1.1688777

Zhang, Z., Kleinstreuer, C., Kim, C. S., & Cheng, Y. S. (2004). Vaporizing Microdroplet Inhalation, Transport, and Deposition in a Human Upper Airway Model. Aerosol Science and Technology, 38(1), 36–49. https://doi.org/10.1080/02786820300985

Zhang, Z., Kleinstreuer, C., Kim, C. S., & Cheng, Y. S. (2004). Vaporizing microdroplet inhalation, transport, and deposition in a human upper airway model. AEROSOL SCIENCE AND TECHNOLOGY, 38(1), 36–49. https://doi.org/10.1080/02786820490247597

Koo, J., & Kleinstreuer, C. (2004). Viscous dissipation effects in microtubes and microchannels. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 47(14-16), 3159–3169. https://doi.org/10.1016/j.ijheatmasstransfer.2004.02.017

Longest, P. W., & Kleinstreuer, C. (2003). Comparison of blood particle deposition models for non-parallel flow domains. JOURNAL OF BIOMECHANICS, 36(3), 421–430. https://doi.org/10.1016/S0021-9290(02)00434-7

Zhang, Z., & Kleinstreuer, C. (2003, November). Computational thermodynamics analysis of vaporizing fuel droplets in the human upper airways. JSME INTERNATIONAL JOURNAL SERIES B-FLUIDS AND THERMAL ENGINEERING, Vol. 46, pp. 563–571. https://doi.org/10.1299/jsmeb.46.563

Buchanan, JR, Kleinstreuer, C., Hyun, S., & Truskey, G. A. (2003). Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. JOURNAL OF BIOMECHANICS, 36(8), 1185–1196. https://doi.org/10.1016/S0021-9290(03)00088-5

Kleinstreuer, C., & Zhang, Z. (2003). Laminar-to-turbulent fluid-particle flows in a human airway model. INTERNATIONAL JOURNAL OF MULTIPHASE FLOW, 29(2), 271–289. https://doi.org/10.1016/S0301-9322(02)00131-3

Koo, J. M., & Kleinstreuer, C. (2003). Liquid flow in microchannels: experimental observations and computational analyses of microfluidics effects. JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 13(5), 568–579. https://doi.org/10.1088/0960-1317/13/5/307

Zhang, Z., & Kleinstreuer, C. (2003). Low-Reynolds-number turbulent flows in locally constricted conduits: A comparison study. AIAA JOURNAL, 41(5), 831–840. https://doi.org/10.2514/2.2044

Longest, P. W., & Kleinstreuer, C. (2003). Numerical simulation of wall shear stress conditions and platelet localization in realistic end-to-side arterial anastomoses. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 125(5), 671–681. https://doi.org/10.1115/1.1613298

Longest, P. W., Kleinstreuer, C., & Archie, J. P. (2003). Particle hemodynamics analysis of Miller cuff arterial anastomosis. JOURNAL OF VASCULAR SURGERY, 38(6), 1353–1362. https://doi.org/10.1016/S0741-5214(03)00950-9

Longest, P. W., & Kleinstreuer, C. (2003). Particle-hemodynamics modeling of the distal end-to-side femoral bypass: effects of graft caliber and graft-end cut. MEDICAL ENGINEERING & PHYSICS, 25(10), 843–858. https://doi.org/10.1016/S1350-4533(03)00124-3

Longest, P. W., Kleinstreuer, C., Truskey, G. A., & Buchanan, JR. (2003). Relation between near-wall residence times of monocytes and early lesion growth in the rabbit aorto-celiac junction. ANNALS OF BIOMEDICAL ENGINEERING, 31(1), 53–64. https://doi.org/10.1114/1.1531635

Zhang, Z., & Kleinstreuer, C. (2003). Species heat and mass transfer in a human upper airway model. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 46(25), 4755–4768. https://doi.org/10.1016/S0017-9310(03)00358-2

Kleinstreuer, C., & Zhang, Z. (2003). Targeted drug aerosol deposition analysis for a four-generation lung airway model with hemispherical tumors. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 125(2), 197–206. https://doi.org/10.1115/1.1543548

Loh, B. G., Hyun, S., Ro, P. I., & Kleinstreuer, C. (2002). Acoustic streaming induced by ultrasonic flexural vibrations and associated enhancement of convective heat transfer. JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 111(2), 875–883. https://doi.org/10.1121/1.1433811

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2002). Aerosol deposition efficiencies and upstream release positions for different inhalation modes in an upper bronchial airway model. AEROSOL SCIENCE AND TECHNOLOGY, 36(7), 828–844. https://doi.org/10.1080/02786820290092078

Zhang, Z., Kleinstreuer, C., Kim, C. S., & Hickey, A. J. (2002). Aerosol transport and deposition in a triple bifurcation bronchial airway model with local tumors. INHALATION TOXICOLOGY, 14(11), 1111–1133. https://doi.org/10.1080/08958370290084809

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2002). Cyclic micron-size particle inhalation and deposition in a triple bifurcation lung airway model. JOURNAL OF AEROSOL SCIENCE, 33(2), 257–281. https://doi.org/10.1016/S0021-8502(01)00170-7

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2002). Gas-solid two-phase flow in a triple bifurcation lung airway model. INTERNATIONAL JOURNAL OF MULTIPHASE FLOW, 28(6), 1021–1046. https://doi.org/10.1016/S0301-9322(02)00011-3

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2002). Micro-particle transport and deposition in a human oral airway model. JOURNAL OF AEROSOL SCIENCE, 33(12), 1635–1652. https://doi.org/10.1016/S0021-8502(02)00122-2

Zhang, Z., & Kleinstreuer, C. (2002). Transient airflow structures and particle transport in a sequentially branching lung airway model. Physics of Fluids (Woodbury, N.Y.), 14(2), 862–880. https://doi.org/10.1063/1.1433495

Kleinstreuer, C. (2001). 'Effects of asymmetric branch flow rates on aerosol deposition in bifurcating airways', by Z. Zhang, C. Kleinstreuer and C. S. Kim - Response. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY, Vol. 25, pp. 127–127. https://doi.org/10.1080/03091900110046952

Longest, P. W., Kleinstreuer, C., & Buchanan, J. R. (2001). A New Near-wall Residence Time Model Applied to Three Arterio-venous Graft End-to-side Anastomoses. Computer Methods in Biomechanics and Biomedical Engineering, 4(5), 379–397. https://doi.org/10.1080/10255840108908015

Hyun, S., Kleinstreuer, C., & Archie, J. P. (2001). Computational particle-hemodynamics analysis and geometric reconstruction after carotid endarterectomy. COMPUTERS IN BIOLOGY AND MEDICINE, 31(5), 365–384. https://doi.org/10.1016/S0010-4825(01)00007-5

Zhang, Z., & Kleinstreuer, C. (2001). Effect of particle inlet distributions on deposition in a triple bifurcation lung airway model. JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG, 14(1), 13–29. https://doi.org/10.1089/08942680152007864

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2001). Effects of curved inlet tubes on air flow and particle deposition in bifurcating lung models. JOURNAL OF BIOMECHANICS, 34(5), 659–669. https://doi.org/10.1016/S0021-9290(00)00233-5

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2001, June). Flow structure and particle transport in a triple bifurcation airway model. JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, Vol. 123, pp. 320–330. https://doi.org/10.1115/1.1359525

Comer, J. K., Kleinstreuer, C., & Zhang, Z. (2001). Flow structures and particle deposition patterns in double-bifurcation airway models. Part 1. Air flow fields. JOURNAL OF FLUID MECHANICS, 435, 25–54. https://doi.org/10.1017/s0022112001003809

Comer, J. K., Kleinstreuer, C., & Kim, C. S. (2001). Flow structures and particle deposition patterns in double-bifurcation airway models. Part 2. Aerosol transport and deposition. JOURNAL OF FLUID MECHANICS, 435, 55–80. https://doi.org/10.1017/s0022112001003810

Kleinstreuer, C., Hyun, S., Buchanan, J. R., Longest, P. W., Archie, J. P., & Truskey, G. A. (2001). Hemodynamic parameters and early intimal thickening in branching blood vessels. Critical Reviews in Biomedical Engineering, 29(1), 1–64. https://doi.org/10.1615/critrevbiomedeng.v29.i1.10

Hyun, S., & Kleinstreuer, C. (2001). Numerical simulation of mixed convection heat and mass transfer in a human inhalation test chamber. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 44(12), 2247–2260. https://doi.org/10.1016/S0017-9310(00)00268-4

Comer, J. K., Kleinstreuer, C., Hyun, S., & Kim, C. S. (2000). Aerosol transport and deposition in sequentially bifurcating airways. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 122(2), 152–158. https://doi.org/10.1115/1.429636

Longest, P. W., Kleinstreuer, C., & Andreotti, P. J. (2000). Computational analyses and design improvements of graft-to-vein anastomoses. CRITICAL REVIEWS IN BIOMEDICAL ENGINEERING, Vol. 28, pp. 141–147. https://doi.org/10.1615/critrevbiomedeng.v28.i12.240

Longest, P. W., & Kleinstreuer, C. (2000). Computational haemodynamics analysis and comparison study of arterio-venous grafts. Journal of Medical Engineering & Technology, 24(3), 102–110.

Hyun, S., Kleinstreuer, C., & Archie, J. P. (2000). Computer simulation and geometric design of endarterectomized carotid artery bifurcations. CRITICAL REVIEWS IN BIOMEDICAL ENGINEERING, Vol. 28, pp. 53–59. https://doi.org/10.1615/critrevbiomedeng.v28.i12.100

Zhang, Z., Kleinstreuer, C., & Kim, C. S. (2000). Effects of asymmetric branch flow rates on aerosol deposition in bifurcating airways. Journal of Medical Engineering & Technology, 24(5), 192–202.

Hyun, S., Kleinstreuer, C., & Archie, J. P. (2000). Hemodynamics analyses of arterial expansions with implications to thrombosis and restenosis. MEDICAL ENGINEERING & PHYSICS, 22(1), 13–27. https://doi.org/10.1016/S1350-4533(00)00006-0

Buchanan, JR, Kleinstreuer, C., & Comer, J. K. (2000). Rheological effects on pulsatile hemodynamics in a stenosed tube. COMPUTERS & FLUIDS, 29(6), 695–724. https://doi.org/10.1016/S0045-7930(99)00019-5

Longest, P. W., Kleinstreuer, C., & Kinsey, J. S. (2000, June). Turbulent three-dimensional air flow and trace gas distribution in an inhalation test chamber. JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, Vol. 122, pp. 403–411. https://doi.org/10.1115/1.483270

Buchanan, JR, Kleinstreuer, C., Truskey, G. A., & Lei, M. (1999). Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction. ATHEROSCLEROSIS, 143(1), 27–40. https://doi.org/10.1016/S0021-9150(98)00264-0

Buchanan, C. D., Kleinstreuer, C., & Longest, P. W. (1998). Analytical solution to flux enhancement in laminar concentrically stratified pipe flow of Bingham and Newtonian fluids. JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME, 120(3), 629–631. https://doi.org/10.1115/1.2820711

Buchanan, JR, & Kleinstreuer, C. (1998). Simulation of particle-hemodynamics in a partially occluded artery segment with implications to the initiation of microemboli and secondary stenoses. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 120(4), 446–454. https://doi.org/10.1115/1.2798013

Lei, M., Archie, J. P., & Kleinstreuer, C. (1997). Computational design of a bypass graft that minimizes wall shear stress gradients in the region of the distal anastomosis. JOURNAL OF VASCULAR SURGERY, 25(4), 637–646. https://doi.org/10.1016/S0741-5214(97)70289-1

Kleinstreuer, C. (1997). Engineering fluid dynamics: An interdisciplinary systems approach. https://doi.org/10.1017/cbo9781139174510

Lei, M., Kleinstreuer, C., & Archie, J. P. (1997, August). Hemodynamic simulations and computer aided designs of graft-artery junctions. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, Vol. 119, pp. 343–348. https://doi.org/10.1115/1.2796099

Kleinstreuer, C., & Li, Z. H. Analysis and computer program for rupture-risk prediction of abdominal aortic aneurysms. Biomedical Engineering Online, 5.

Kleinstreuer, C. Biofluid dynamics. Boca Raton, FL: CRC/Taylor & Francis.

Kleinstreuer, C., Li, J., & Feng, Y. Computational analysis of enhanced cooling performance and pressure drop for nanofluid flow
in microchannels. In E. M. W.J. Minkowycz, Sparrow, & J. P. Abraham (Eds.), Advanced in numerical heat transfer (pp. 250–273). Boca Raton: CRC Press/Taylor & Francis Group.

Kleinstreuer, C. Computational nanofluid flow and heat transfer in microchannels. Handbook of Fluid Dynamics, 2nd Edition.

Kleinstreuer, C. Entropy generation analysis for nanofluid flow in microchannels. Journal of Heat Transfer, 132(12).

Kleinstreuer, C. Microsystems and microfluidics. Handbook of Fluid Dynamics, 2nd Edition.