Claude L. Hughes

Works (5)

Updated: July 5th, 2023 15:44

2016 article

Ligand-Mediated Toxicology: Characterization and Translational Prospects

TRANSLATIONAL TOXICOLOGY: DEFINING A NEW THERAPEUTIC DISCIPLINE, pp. 113–137.

By: R. Ansari*, C. Hughes* & K. Husain*

author keywords: Translational toxicology; Endocrine disruption; Epigenetics; Ligand; Receptor mediated toxicity; Xenosensors
TL;DR: In biochemistry a ligand is a molecule that binds to a receptor or other biomolecule that forms a complex and produces a biological effect. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2016 article

The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline

TRANSLATIONAL TOXICOLOGY: DEFINING A NEW THERAPEUTIC DISCIPLINE, pp. 3–44.

By: C. Hughes*, M. Waters *, D. Allen * & I. Obasanjo *

author keywords: Translational toxicology developmental exposures; Obstetrical, neonatal, childhood and adolescent therapies
TL;DR: This chapter will broadly update new insights that have been gained over the last 2 years regarding the progress of translational developmental toxicology toward becoming a therapeutic discipline. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Cigarette smoking and ovarian function

Ovarian Toxicology, 2nd Edition, 229–248.

By: A. Gannon, J. Sadeu, S. Agarwal, C. Hughes & W. Foster

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Effects of Dietary Chromium Methionine on Growth Performance, Carcass Composition, Meat Colour and Expression of the Colour-related Gene Myoglobin of Growing-finishing Pigs

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 26(7), 1021–1029.

By: Y. Li *, N. Zhu *, P. Niu *, F. Shi, C. Hughes n, G. Tian, R. Huang *

author keywords: Growing-finishing Pigs; Chromium Methionine; Meat Colour; Myoglobin
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Modeling Endocrine Control of the Pituitary-Ovarian Axis: Androgenic Influence and Chaotic Dynamics

BULLETIN OF MATHEMATICAL BIOLOGY, 76(1), 136–156.

By: A. Hendrix  n, C. Hughes n & J. Selgrade n

author keywords: Modeling; Androgens
MeSH headings : Androgens / physiology; Computer Simulation; Feedback, Physiological; Female; Follicle Stimulating Hormone / physiology; Humans; Hypothalamo-Hypophyseal System / physiology; Luteinizing Hormone / physiology; Mathematical Concepts; Menstrual Cycle / physiology; Models, Biological; Nonlinear Dynamics; Ovarian Follicle / physiology; Ovary / physiology; Polycystic Ovary Syndrome / etiology; Polycystic Ovary Syndrome / physiopathology; Systems Biology
TL;DR: It is shown that varying a follicular growth parameter produces preantral stockpiling and a period-doubling cascade resulting in apparent chaotic menstrual cycle behavior and a new model may allow investigators to study possible interventions returning acyclic patients to regular cycles and guide developments of individualized treatments for PCOS patients. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

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