Works (2)

Updated: July 29th, 2023 21:16

2022 journal article

Effects of developmental exposure to FireMaster (R) 550 (FM 550) on microglia density, reactivity and morphology in a prosocial animal model

NEUROTOXICOLOGY, 91, 140–154.

By: W. Marinello n, S. Gillera n, M. Fanning n, L. Malinsky n, C. Rhodes n, B. Horman n, H. Patisaul n

author keywords: Prefrontal cortex; Sex difference; Neurodevelopment; Endocrine disrupting chemicals; Flame retardants; Vole
MeSH headings : Animals; Arvicolinae; Female; Humans; Male; Mice; Microglia; Models, Animal; Organophosphates; Polybrominated Biphenyls; Pregnancy; Rats
TL;DR: Overall, FM 550 exposure resulted in reduced numbers of microglia in most regions examined, with the 1000µg FM 550 exposed males particularly affected. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 20, 2022

2016 journal article

Sex differences in microglial colonization and vulnerabilities to endocrine disruption in the social brain

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 238, 39–46.

By: M. Rebuli n, P. Gibson n, C. Rhodes n, B. Cushing* & H. Patisaul n

author keywords: Vole; Rat; Hypothalamus; EDC; Sexual differentiation; Puberty
MeSH headings : Amygdala / cytology; Amygdala / drug effects; Animals; Animals, Newborn; Arvicolinae; Benzhydryl Compounds / toxicity; Brain / cytology; Brain / drug effects; Brain / growth & development; Dentate Gyrus / cytology; Dentate Gyrus / drug effects; Endocrine Disruptors / toxicity; Female; Male; Microglia / drug effects; Microglia / metabolism; Phenols / toxicity; Rats, Wistar; Sex Characteristics; Social Behavior; Somatosensory Cortex / cytology; Somatosensory Cortex / drug effects
TL;DR: This work is the first to observe that developmental exposure to the synthetic estrogen ethinyl estradiol (EE) or BPA alters the sex-specific colonization of the hippocampus and amygdala by microglia. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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