Works (194)

Updated: December 11th, 2024 12:30

2024 journal article

Combinatorial metabolomic and transcriptomic analysis of muscle growth in hybrid striped bass (female white bass <i>Morone chrysops</i> x male striped bass <i>M. saxatilis</i>)

BMC GENOMICS, 25(1).

By: S. Rajab n, L. Andersen n, L. Kenter*, D. Berlinsky*, R. Borski n, A. McGinty n, C. Ashwell n, P. Ferket n, H. Daniels n, B. Reading n

author keywords: Machine learning; Genome; Growth; Fish; Striped bass; Metabolomics; Transcriptomics
Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2024 journal article

Selection for high and low antibody responses to sheep red blood cells influences cytokine and chemokine expression in chicken peripheral blood leukocytes and splenic tissue

Poultry Science.

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: July 1, 2024

2023 journal article

Combining supervised machine learning with statistics reveals differential gene expression patterns related to energy metabolism in the jejuna of chickens divergently selected for antibody response to sheep red blood cells

POULTRY SCIENCE, 102(7).

By: S. Nolin n, R. Taylor Jr, F. Edens n, P. Siegel* & C. Ashwell*

author keywords: gene expression; machine learning; antibody response; genetic selection; Virginia Tech HAS and LAS
MeSH headings : Animals; Adenosine Triphosphate; Antibody Formation; Chickens / genetics; Energy Metabolism; Erythrocytes; Gene Expression; Jejunum; Sheep / genetics; Supervised Machine Learning
TL;DR: Insight is provided into energetic resource needs and allocations in the jejunum in response to genetic selection and antigen exposure in HAS and LAS which may help explain phenotypic differences observed in antibody response. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 3, 2023

2023 journal article

Transgenerational epigenetic inheritance and immunity in chickens that vary in Marek's disease resistance

Poultry Science.

TL;DR: Results provide very solid evidence that DNA methylation patterns are transgenerational epigenetic inheritance (TEI) in chickens and also play a vital role in MD tumorigenesis and other immune responses; the specific methylated regions may be important modulators of general immunity. (via Semantic Scholar)
Source: ORCID
Added: January 31, 2024

2021 journal article

Effect of Nutritional Variance of Energy and Crude Protein on Sex Ratio and Development of W-36 Parent Offspring

POULTRY SCIENCE JOURNAL, 9(2), 255–262.

By: M. Wooten n, Z. Lowman n & C. Ashwell n

author keywords: Hen; Layer; Sex ratio; Nutrition; Reproduction
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 28, 2022

2020 journal article

Evaluation via Supervised Machine Learning of the Broiler Pectoralis Major and Liver Transcriptome in Association With the Muscle Myopathy Wooden Breast

FRONTIERS IN PHYSIOLOGY, 11.

By: C. Phillips n, B. Reading n, M. Livingston n, K. Livingston n & C. Ashwell n

author keywords: wooden breast; machine learning; poultry transcriptomics; support vector machines; artificial neural networks; transforming growth factor
TL;DR: The information provided has revealed many molecules and pathways making up a complex molecular mechanism involved with the progression of wooden breast and suggests that the etiology of the myopathy is not limited to activity in the muscle alone, but is an altered systemic pathology. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2019 journal article

Effects of acute and chronic heat stress on the performance, egg quality, body temperature, and blood gas parameters of laying hens

POULTRY SCIENCE, 98(12), 6684–6692.

By: N. Barrett*, K. Rowland*, C. Schmidt*, S. Lamont*, M. Rothschild*, C. Ashwell n, M. Persia*

author keywords: heat stress; performance; laying hen; blood chemistry; egg quality
MeSH headings : Animals; Blood Gas Analysis / veterinary; Body Temperature; Body Weight; Chickens / blood; Chickens / physiology; Eating; Female; Heat-Shock Response / physiology; Ovum / physiology
TL;DR: The cyclic HS had a significant effect on the performance, egg quality, and blood chemistry over the 4-wk HS. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 13, 2020

2019 journal article

Genetic analysis of production, physiological, and egg quality traits in heat-challenged commercial white egg-laying hens using 600k SNP array data

GENETICS SELECTION EVOLUTION, 51(1).

By: K. Rowland*, C. Ashwell n, M. Persia*, M. Rothschild*, C. Schmidt* & S. Lamont*

MeSH headings : Agriculture; Animal Husbandry; Animals; Chickens / genetics; Chickens / physiology; Eggs; Female; Heat-Shock Response / genetics; Hot Temperature; Oviposition; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable
TL;DR: Estimated heritabilities differed from 0 for 17 traits, which indicates that they are under genetic control and that there is potential for improving these traits through selective breeding. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: July 15, 2019

2019 journal article

Natural Selection Footprints Among African Chicken Breeds and Village Ecotypes

FRONTIERS IN GENETICS, 10.

author keywords: selection signatures; environmental stresses; African chicken; F-ST; runs of homozygosity
TL;DR: Inter-population FST among Egyptian populations reflected genetic mechanisms for the Fayoumi resistance to Newcastle Disease Virus, while FST between Egyptian and Rwanda–Uganda populations indicated the Secreted frizzled related protein 2, SFRP2, that contributes to melanogenic activity and most likely enhances the Dandarawi chicken adaptation to high-intensity of solar radiation in Southern Egypt. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID
Added: May 28, 2019

2018 conference paper

2018 Abstracts

British Poultry Abstracts, 14(1), 1–35.

By: I. Dunn, T. Doki, J. Oluyemi, A. Ologhobo, P. McDonald, R. Edwards, J. Greenhalgh, C. Morgan ...

Event: Glasgow University Tours

Source: ORCID
Added: February 4, 2021

2018 journal article

Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

BMC GENOMICS, 19(1).

By: M. Monson*, A. Van Goor*, C. Ashwell n, M. Persia*, M. Rothschild*, C. Schmidt*, S. Lamont*

author keywords: Heat stress; Lipopolysaccharide; Chicken; RNA-seq; Transcriptome; Bursa
MeSH headings : Animals; Birnaviridae Infections / drug therapy; Birnaviridae Infections / immunology; Birnaviridae Infections / veterinary; Birnaviridae Infections / virology; Bursa of Fabricius / immunology; Bursa of Fabricius / metabolism; Bursa of Fabricius / virology; Chickens / genetics; Chickens / immunology; Gene Expression Regulation; Gene Regulatory Networks; High-Throughput Nucleotide Sequencing; Hot Temperature; Immunologic Factors / pharmacology; Lipopolysaccharides / immunology; Poultry Diseases / genetics; Poultry Diseases / immunology; Poultry Diseases / virology; Transcriptome
TL;DR: RNA-seq identified genes and pathways involved in bursal responses to heat stress and LPS and elucidated that these effects were greatest in the combined treatment, which can inform future research on heat stress in poultry and could prove useful for improving disease resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: October 19, 2018

2018 journal article

Regions of Genomic Control Identified for Feed Efficiency in Laying Hens under Heat Stress

Animal Industry Report, 664(1), 52.

By: K. Rowland, J. Hsieh, N. Barrett, C. Ashwell, M. Persia, M. Rothschild, C. Schmidt, S. Lamont

Source: ORCID
Added: February 4, 2021

2017 journal article

Evidence of Natural Selection Footprints Among Some African Chicken Breeds and Village Ecotypes

Animal Industry Report, 663(1), 40.

By: A. Elbetagy, F. Bertolini, D. Fleming, A. Van Goor, C. Schmidt, S. Lamont, M. Rothschild

Source: ORCID
Added: February 4, 2021

2017 journal article

Exposure to Heat Stress and anImmune Stimulus AffectsGene Expression in Chicken Immune Tissues

Animal Industry Report, 663(1), 47.

By: M. Monson, A. Van Goor, C. Ashwell, M. Persia, M. Rothschild, C. Schmidt, S. Lamont

Source: ORCID
Added: February 4, 2021

2017 journal article

Genome-wide standing variation facilitates long-term response to bidirectional selection for antibody response in chickens

BMC GENOMICS, 18(1).

By: M. Lillie*, Z. Sheng*, C. Honaker*, B. Dorshorst*, C. Ashwell n, P. Siegel*, O. Carlborg*

Contributors: C. Ashwell n

author keywords: Pooled genome sequencing; Selective sweeps; Virginia chicken lines; Sheep red blood cells; Antibody response
MeSH headings : Alleles; Animals; Chickens; Erythrocytes / immunology; Evolution, Molecular; Genetic Variation; Genomics; Histocompatibility Antigens / genetics; Immunity, Humoral / genetics; Receptors, Transforming Growth Factor beta / genetics; Selection, Genetic; Sheep / blood
TL;DR: The extensive genomic changes highlight the polygenic genetic architecture of antibody response in these chicken populations, which are derived from a common founder population, demonstrating the extent of standing immunogenetic variation available at the onset of selection. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Genomic Comparison of Indigenous African and Northern European Chickens Reveals Putative Mechanisms of Stress Tolerance Related to Environmental Selection Pressure

G3-GENES GENOMES GENETICS, 7(5), 1525–1537.

By: D. Fleming*, S. Weigend*, H. Simianer*, A. Weigend*, M. Rothschild*, C. Schmidt*, C. Ashwell n, M. Persia*, J. Reecy*, S. Lamont*

author keywords: tolerance; selective pressure; genomic variation; adaptation; environment
MeSH headings : Animals; Chickens / genetics; Chickens / physiology; Environment; Genome; Haplotypes; Homozygote; Polymorphism, Genetic; Selection, Genetic; Stress, Physiological / genetics
TL;DR: Examination of the divergent populations has provided new insight into genes under possible selection related to tolerance of a population’s indigenous environment that may be baselines for examining the genomic contribution to tolerance adaptions. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Genomic comparison of indigenous African and Northern European chickens reveals putative mechanisms of stress tolerance related to environmental selection pressure

G3: Genes, Genomes, Genetics, 7(5), 1525–1537.

By: D. Fleming, S. Weigend, H. Simianer, A. Weigend, M. Rothschild, C. Schmidt, C. Ashwell, M. Persia, J. Reecy, S. Lamont

Source: ORCID
Added: February 4, 2021

2017 journal article

Protein and Caloric Intake on the Reproductive Performance Parameters of Hy-Line W-36 Parent Stock males

International Journal of Poultry Science, 16, 242–247.

By: Z. Lowman, M. Wooten, C. Ashwell, K. Anderson & H. Barnes

Source: ORCID
Added: February 4, 2021

2017 journal article

Unique genetic responses revealed in RNA-seq of the spleen of chickens stimulated with lipopolysaccharide and short-term heat

PLOS ONE, 12(2).

By: A. Van Goor*, C. Ashwell n, M. Persia*, M. Rothschild*, C. Schmidt* & S. Lamont*

MeSH headings : Animals; Biomarkers; Blood Chemical Analysis; Body Temperature; Chickens / blood; Chickens / genetics; Chickens / immunology; Computational Biology / methods; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Genome; High-Throughput Nucleotide Sequencing; Hot Temperature; Lipopolysaccharides / immunology; Reproducibility of Results; Spleen / immunology; Spleen / metabolism; Spleen / radiation effects
TL;DR: Transcriptional changes in spleens revealed pathways impacted by these stressors such as Remodelling of Epithelial Adherens Junctions due to heat stress, Granulocyte Adhesion and Diapedesis due to LPS, and Hepatic Fibrosis/Hepatic Stellate Cell Activation due to EMT. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Unique genetic responses revealed in RNAseq of the spleen of chickens stimulated with lipopolysaccharide and short-term heat

By: C. Ashwell, M. Persia, S. Lamont, M. Rothschild, C. Schmidt & A. Van Goor

Source: ORCID
Added: February 4, 2021

2016 journal article

Differences in mRNA populations of short and long bovine conceptuses on Day 15 of gestation

MOLECULAR REPRODUCTION AND DEVELOPMENT, 83(5), 424–441.

By: C. Barnwell n, P. Farin n, C. Ashwell n, W. Farmer n, S. Galphin n & C. Farin n

MeSH headings : Animals; Cattle; Female; Gestational Age; Morula / cytology; Morula / metabolism; Pregnancy; RNA, Messenger / metabolism
TL;DR: Differences in gene expression were identified between conceptuses recovered on Day 15 of gestation, based on their length, which may be used to identify genes and cellular pathways involved in enhanced conceptus elongation that could serve as markers of successful pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Differences in mRNA populations of short and long bovine conceptuses on Day 15 of gestation

Molecular Reproduction and Development, 83(5), 424–441.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2016 journal article

Genomes of African Chickens Show Evolutionary Response to Environmental Stress

Animal Industry Report, 662(1), 62.

By: D. Fleming, J. Koltes, A. Markey, C. Schmidt, C. Ashwell, M. Rothschild, M. Persia, J. Reecy, S. Lamont

Source: ORCID
Added: February 4, 2021

2016 journal article

Genomic analysis of Ugandan and Rwandan chicken ecotypes using a 600 k genotyping array

BMC GENOMICS, 17(1).

By: D. Fleming*, J. Koltes*, A. Markey*, C. Schmidt*, C. Ashwell n, M. Rothschild*, M. Persia*, J. Reecy*, S. Lamont*

author keywords: Homozygosity; Selection signatures; Stress response
MeSH headings : Animals; Chickens / genetics; Computational Biology / methods; Ecotype; Gene Ontology; Genetics, Population; Genome; Genomics / methods; Genotype; Genotyping Techniques; Homozygote; Selection, Genetic
TL;DR: The study suggests that these populations have alleles under selective pressure from their environment, which may aid in adaptation to harsh environments. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

P4060 Runs of homozygosity reveal natural selection footprints of some African chicken breeds and village ecotypes

Journal of Animal Science, 94(suppl_4), 108–109.

By: A. Elbeltagy, D. Fleming, F. Bertolini, A. Van Goor, C. Ashwell, C. Schmidt, S. Lamont, M. Rothschild

Source: ORCID
Added: February 4, 2021

2016 journal article

Parental diet effects on egg component weights and shell quality

JOURNAL OF APPLIED POULTRY RESEARCH, 25(3), 437–442.

By: Z. Lowman n & C. Ashwell n

author keywords: Egg components; protein; energy
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Quantitative trait loci identified for blood chemistry components of an advanced intercross line of chickens under heat stress

BMC GENOMICS, 17(1).

By: A. Van Goor*, C. Ashwell n, M. Persia*, M. Rothschild*, C. Schmidt* & S. Lamont*

MeSH headings : Angiopoietins / genetics; Animals; Blood Chemical Analysis; Chickens / blood; Chickens / genetics; Crosses, Genetic; Genome-Wide Association Study; Genotype; Heat-Shock Response / genetics; Hot Temperature; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci
TL;DR: The results of this study contribute to knowledge of levels and heritabilities of several blood components of chickens under thermoneutral and heat stress conditions and identify the Angiopoietin pathway as likely involved in the response to heat stress in chickens. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 article

Runs of homozygosity reveal natural selection footprints of some African chicken breeds and village ecotypes

Elbeltagy, A. R., Fleming, D. S., Bertolini, F., Van Goor, A. G., Ashwell, C. M., Schmidt, C. J., … Rothschild, M. F. (2016, September). JOURNAL OF ANIMAL SCIENCE, Vol. 94, pp. 108–109.

By: A. Elbeltagy*, D. Fleming*, F. Bertolini*, A. Van Goor*, C. Ashwell n, C. Schmidt*, S. Lamont*, M. Rothschild*

author keywords: runs of homozygosity; natural selection; African chicken
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Single nucleotide variant discovery of highly inbred Leghorn and Fayoumi chicken breeds using pooled whole genome resequencing data reveals insights into phenotype differences

BMC GENOMICS, 17(1).

By: D. Fleming*, J. Koltes*, E. Fritz-Waters*, M. Rothschild*, C. Schmidt*, C. Ashwell n, M. Persia*, J. Reecy*, S. Lamont*

author keywords: Resequencing; Single nucleotide variant; Genomic diversity
MeSH headings : Animals; Breeding; Chickens / genetics; Chromosomes; Computational Biology / methods; Genetic Variation; Genomics / methods; Mutation; Phenotype; Polymorphism, Single Nucleotide; Reproducibility of Results
TL;DR: Variant analysis elucidated GO functions indicative of breed-predominant phenotypes related to genomic variation in the lines, showing a possible link between the genetic variants and breed traits. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

UNIQUE GENETIC RESPONSES REVEALED IN RNA-SEQ OF THE SPLEEN OF CHICKENS STIMULATED WITH LIPOPOLYSACCHARIDE AND HEAT

The Genomics of Heat Stress and Immune Response in Chickens, 1001, 102.

By: A. Van Goor, C. Ashwell, M. Persia, M. Rothschild, C. Schmidt & S. Lamont

Source: ORCID
Added: February 4, 2021

2015 journal article

A Genomic Duplication is Associated with Ectopic Eomesodermin Expression in the Embryonic Chicken Comb and Two Duplex-comb Phenotypes

PLOS GENETICS, 11(3).

By: B. Dorshorst*, M. Harun-Or-Rashid*, A. Bagherpoor*, C. Rubin*, C. Ashwell n, D. Gourichon, M. Tixier-Boichard*, F. Hallbook*, L. Andersson*

MeSH headings : Animals; Chick Embryo; Chickens / genetics; Chickens / growth & development; Ectoderm / embryology; Ectoderm / growth & development; Ectoderm / metabolism; Embryonic Development / genetics; Gastrulation / genetics; Gene Expression Regulation, Developmental; Genes, Duplicate; Genome; Genomics; Haplotypes; Mutation; T-Box Domain Proteins / biosynthesis; T-Box Domain Proteins / genetics
TL;DR: It is shown that the two Duplex-comb alleles, V-shaped and Buttercup, are both associated with a 20 Kb tandem duplication containing several conserved putative regulatory elements located 200 Kb upstream of the eomesodermin gene (EOMES). (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Breed differences in physiologic response to embryonic thermal conditioning and post-hatch heat stress in chickens

Animal Industry Report, 661(1), 58.

By: S. Lamont, M. Kaiser, M. Rothschild, M. Persia, C. Ashwell & C. Schmidt

Source: ORCID
Added: February 4, 2021

2015 journal article

Genetic Markers Found for Response to Heat Stress in Chickens

Animal Industry Report, 661(1), 60.

By: A. Bjorkquist, M. Rothschild, M. Persia, C. Ashwell, C. Schmidt & S. Lamont

Source: ORCID
Added: February 4, 2021

2015 journal article

Identification of quantitative trait loci for body temperature, body weight, breast yield, and digestibility in an advanced intercross line of chickens under heat stress

GENETICS SELECTION EVOLUTION, 47(1).

By: A. Van Goor*, K. Bolek*, C. Ashwell n, M. Persia*, M. Rothschild*, C. Schmidt*, S. Lamont*

MeSH headings : Animals; Body Temperature / genetics; Body Weight / genetics; Breeding; Chickens; Crosses, Genetic; Gene Frequency; Genetic Association Studies; Genome-Wide Association Study; Genotype; Hot Temperature; Inheritance Patterns; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Quantitative Trait, Heritable; Stress, Physiological
TL;DR: This is the first study to estimate heritabilities and perform genome-wide association study (GWAS) for these traits and changes in BT and BW using this AIL for traits measured during heat stress, and these QTL may facilitate selection for improved animal performance in hot climatic conditions. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

RNA-seq: primary cells, cell lines and heat stress

BioRxiv, 013979.

By: C. Schmdt, E. Pritchett, L. Sun, R. Davis, A. Hubbard, K. Kniel, S. Markland, Q. Wang ...

Source: ORCID
Added: February 4, 2021

2015 journal article

The effect of hyperammonemia on myostatin and myogenic regulatory factor gene expression in broiler embryos

ANIMAL, 9(6), 992–999.

By: R. Stern n, C. Ashwell n, S. Dasarathy* & P. Mozdziak n

Contributors: R. Stern n, C. Ashwell n, S. Dasarathy* & P. Mozdziak n

author keywords: broiler; hyperammonemia; myogenesis; myogenic regulatory factor; myostatin
MeSH headings : Animals; Chick Embryo; Chickens; Gene Expression Regulation; Hyperammonemia / genetics; Hyperammonemia / metabolism; Hyperammonemia / veterinary; Muscle Development / genetics; Myogenic Regulatory Factors / genetics; Myogenic Regulatory Factors / metabolism; Myogenin / genetics; Myogenin / metabolism; Pectoralis Muscles / metabolism; Poultry Diseases / genetics; Poultry Diseases / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism
TL;DR: Overall, it appears possible to inhibit myostatin expression through hyperammonemia, which is expected to have a positive effect on embryonic myogenesis and postnatal muscle growth. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Third Report on Chicken Genes and Chromosomes 2015

CYTOGENETIC AND GENOME RESEARCH, 145(2), 78–179.

By: C. Ashwell (1 connected NC State author and many others, 104 authors in total )

MeSH headings : Animals; Chickens / classification; Chickens / genetics; Chickens / physiology; Chromosome Mapping; Chromosomes / genetics; DNA Methylation; Evolution, Molecular; Female; Gene Expression Profiling; Genetic Variation; Genomics / methods; In Situ Hybridization, Fluorescence / methods; Male; Molecular Sequence Annotation; Phylogeny
TL;DR: The Third Report on Chicken Genes and Chromosomes summarizes the current efforts to complete the gaps in the genome and describes the progress that has been made in genomic annotation, particularly with respect to noncoding RNAs and genetic variants. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Third report on chicken genes and chromosomes 2015

Cytogenetic and Genome Research, 145(2), 78–179.

By: M. Schmid, J. Smith, D. Burt, B. Aken, P. Antin, A. Archibald, C. Ashwell, P. Blackshear ...

Source: ORCID
Added: February 4, 2021

2015 journal article

Transcriptome Analysis of Post-Hatch Breast Muscle in Legacy and Modern Broiler Chickens Reveals Enrichment of Several Regulators of Myogenic Growth

PLOS ONE, 10(3).

By: R. Davis*, S. Lamont*, M. Rothschild*, M. Persia*, C. Ashwell n & C. Schmidt*

MeSH headings : Animals; Cattle; Chickens; Gene Expression Profiling; Humans; Mice; Muscle Development / genetics; Oviposition; Pectoralis Muscles / cytology; Pectoralis Muscles / growth & development; Pectoralis Muscles / innervation; Pectoralis Muscles / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sequence Analysis, RNA; Time Factors
TL;DR: Differences in the ratios of several positive and negative myogenic growth regulators may help explain the differences underlying the enhanced growth characteristics of the modern broilers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Transcriptome response to heat stress in a chicken hepatocellular carcinoma cell line

CELL STRESS & CHAPERONES, 20(6), 939–950.

By: L. Sun*, S. Lamont*, A. Cooksey*, F. McCarthy*, C. Tudor*, K. Vijay-Shanker*, R. DeRita*, M. Rothschild* ...

author keywords: Transcriptome; RNA-seq; Heat stress; Chicken; LMH cells
MeSH headings : Animals; Carcinoma, Hepatocellular / genetics; Cell Line, Tumor; Chickens; Heat-Shock Response / genetics; Heat-Shock Response / physiology; Hot Temperature; Transcriptome / genetics
TL;DR: The identified biological processes and pathways likely to function in adapting cells and organisms to hyperthermic stress should provide important insight to future efforts attempting to improve species abilities to withstand heat stress through genome-wide association studies and breeding. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

A cis-Regulatory Mutation of PDSS2 Causes Silky-Feather in Chickens

PLOS GENETICS, 10(8).

By: C. Feng*, Y. Gao*, B. Dorshorst*, C. Song*, X. Gu*, Q. Li*, J. Li*, T. Liu* ...

MeSH headings : Alkyl and Aryl Transferases / genetics; Animals; Breeding; Chickens / genetics; Feathers / growth & development; Feathers / metabolism; Gene Expression Regulation, Developmental; Genetic Linkage; Mutation; Phenotype; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid
TL;DR: A new example of feather structure variation associated with a spontaneous mutation is reported and the C to G transversion is shown to remarkably reduce PDSS2 promoter activity in vitro. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

A cis-regulatory mutation of PDSS2 causes silky-feather in chickens

PLoS Genetics, 10(8), e1004576.

By: C. Feng, Y. Gao, B. Dorshorst, C. Song, X. Gu, Q. Li, J. Li, T. Liu ...

Source: ORCID
Added: February 4, 2021

2014 journal article

Genetic Variation within the Mx Gene of Commercially Selected Chicken Lines Reveals Multiple Haplotypes, Recombination and a Protein under Selection Pressure

PLoS ONE, 9(9), e108054.

By: J. Fulton*, J. Arango*, R. Ali n, E. Bohorquez n, A. Lund*, C. Ashwell n, P. Settar*, N. O'Sullivan*, M. Koci n

Contributors: J. Fulton*, J. Arango*, R. Ali n, E. Bohorquez n, A. Lund*, C. Ashwell n, P. Settar*, . N.P. O'Sullivan, M. Koci n

Ed(s): A. Arez

MeSH headings : Animals; Base Sequence; Chickens / genetics; DNA; Haplotypes; Molecular Sequence Data; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proteins / genetics; Recombination, Genetic; Selection, Genetic; Untranslated Regions
TL;DR: Results suggest the conflicting reports in the literature describing the impact of the different SNP on chicken Mx function may be due to the varying context of haplotypes present in the populations studied. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2014 journal article

Genetic variation within the Mx gene of commercially selected chicken lines reveals multiple haplotypes, recombination and a protein under selection pressure

PloS One, 9(9), e108054.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2014 conference paper

NUTRITIONAL IMPRINTING: EARLY DIETARY MANUPULATIONS

Advancing Poultry Production Massey Technical Update Conference, 37.

By: R. Angel & C. Ashwell

Source: ORCID
Added: February 4, 2021

2014 journal article

QTL for body composition traits during heat stress revealed in an advanced intercross line of chickens

Change, 55(36), 2–27.

By: A. Bjorkquist, C. Ashwell, M. Persia, M. Rothschild, C. Schmidt & S. Lamont

Source: ORCID
Added: February 4, 2021

2014 journal article

RNA-seq analysis of broiler liver transcriptome reveals novel responses to high ambient temperature

BMC GENOMICS, 15(1).

By: D. Coble*, D. Fleming*, M. Persia*, C. Ashwell n, M. Rothschild*, C. Schmidt*, S. Lamont*

MeSH headings : Animals; Chickens / genetics; Chromosome Mapping; Down-Regulation; Gene Library; Gene Regulatory Networks; Genome; Liver / metabolism; Sequence Analysis, RNA; Signal Transduction; Temperature; Transcriptome; Up-Regulation
TL;DR: The gene expression differences in the liver transcriptome of the heat-exposed broilers reflected physiological responses to decrease internal temperature, reduce hyperthermia-induced apoptosis, and promote tissue repair, which highlight specific physiologic mechanisms by which broilers reduce the effects of exposure to high ambient temperature. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

ZS Lowman, FW Edens, CM Ashwell and SJ Nolin

International Journal of Poultry Science, 13(2), 114–123.

By: I. In

Source: ORCID
Added: February 4, 2021

2013 journal article

Atherosclerosis-susceptible and atherosclerosis-resistant pigeon aortic cells express different genes in vivo

POULTRY SCIENCE, 92(10), 2668–2680.

By: J. Anderson*, C. Ashwell n, S. Smith*, R. Shine*, E. Smith* & R. Taylor*

author keywords: atherosclerosis; pigeon; aorta; Show Racer; White Carneau
MeSH headings : Actins / genetics; Actins / metabolism; Animals; Aorta / metabolism; Aorta / pathology; Aortic Diseases / genetics; Aortic Diseases / metabolism; Aortic Diseases / veterinary; Atherosclerosis / genetics; Atherosclerosis / metabolism; Atherosclerosis / veterinary; Bird Diseases / genetics; Bird Diseases / metabolism; Columbidae; DNA Copy Number Variations; Disease Resistance; Gene Expression Regulation; Oligonucleotide Array Sequence Analysis / veterinary; Tissue Array Analysis / veterinary
TL;DR: Actin cytoskeletal remodeling appears to be one of the first differences between susceptible and resistant breeds, lending support to the smooth muscle cell phenotypic reversion hypothesis of human atherogenesis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Atherosclerosis-susceptible and atherosclerosis-resistant pigeon aortic cells express different genes in vivo

Poultry Science, 92(10), 2668–2680.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2013 journal article

Insulin-like growth factor-I gene polymorphism associations with growth, body composition, skeleton integrity and metabolic traits in chickens.

Asian Journal of Poultry Science, 9(4), 13351–13354.

By: A. Al-Hassani, D. Al-Hassani, I. Abdul-Hassan, H. Abbasi, M. Kazemi, A. Ali, K. Javed, A. Ali ...

Source: ORCID
Added: February 4, 2021

2013 journal article

Metabolic profiling of late-term turkey embryos by microarrays

POULTRY SCIENCE, 92(4), 1011–1028.

By: J. Oliveira n, S. Druyan n, Z. Uni*, C. Ashwell n & P. Ferket n

author keywords: poultry embryo; turkey; gene expression; microarray; metabolism
MeSH headings : Animals; Energy Metabolism; Gene Expression Profiling / veterinary; Gene Expression Regulation, Developmental; Liver / embryology; Liver / metabolism; Metabolome; Muscle, Skeletal / embryology; Muscle, Skeletal / metabolism; Oligonucleotide Array Sequence Analysis / veterinary; Turkeys / embryology; Turkeys / metabolism
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Metabolic profiling of late-term turkey embryos by microarrays

Poultry Science, 92(4), 1011–1028.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2013 journal article

Metabolic profiling of late-term turkey embryos by microarrays.

Poultry Science, 92(4), 1011–1028.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2013 journal article

RNA-SEQ ANALYSIS OF BROILER LIVER Transcriptome reveals novel responses to heat stress

The Effects of Biotic and Abiotic Stressors on Gene Expression in Chickens, 94.

By: D. Coble, D. Fleming, M. Persia, C. Ashwell, M. Rothschild, C. Schmidt, S. Lamont

Source: ORCID
Added: February 4, 2021

2013 conference paper

Selective Sweeps In Lines Selected For Antibody Response To Sheep Red Blood Cells

Plant and Animal Genome XXI Conference. Presented at the Plant and Animal Genome.

By: C. Ashwell

Event: Plant and Animal Genome

Source: ORCID
Added: February 4, 2021

2012 journal article

Actigen Influence on the Gene Expression of Heat Shock Proteins in Ross 708 Broiler Chickens.

By: Z. Lowman & others

Source: ORCID
Added: February 4, 2021

2012 journal article

Cell Walls of Saccharomyces cerevisiae Differentially Modulated Innate Immunity and Glucose Metabolism during Late Systemic Inflammation

PLoS ONE, 7(1), e30323.

By: B. Baurhoo*, P. Ferket n, C. Ashwell n, J. de Oliviera n & X. Zhao*

Ed(s): D. Chakravortty

MeSH headings : Analysis of Variance; Animals; Anti-Bacterial Agents / immunology; Anti-Bacterial Agents / pharmacology; Carbohydrate Metabolism / drug effects; Cell Wall / chemistry; Cell Wall / immunology; Chickens; Gene Expression Profiling; Glucose / metabolism; Humans; Immunity, Innate / drug effects; Immunity, Innate / immunology; Inflammation / genetics; Inflammation / immunology; Inflammation / metabolism; Intestinal Mucosa / metabolism; Intestines / drug effects; Intestines / immunology; Lipopolysaccharides / immunology; Lipopolysaccharides / pharmacology; Liver / drug effects; Liver / immunology; Liver / metabolism; Mannose / immunology; Oligonucleotide Array Sequence Analysis; Oligosaccharides / immunology; Oligosaccharides / pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae / chemistry; Saccharomyces cerevisiae / immunology; Salmonella typhimurium / chemistry; Salmonella typhimurium / drug effects; Salmonella typhimurium / immunology; Virginiamycin / immunology; Virginiamycin / pharmacology
TL;DR: MOS terminated inflammation earlier than VIRG and reduced glucose mobilization, thus representing a novel biological strategy to alleviate Salmonella-induced systemic inflammation in human and animal hosts. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2012 journal article

Direct fed microbial supplementation repartitions host energy to the immune system

JOURNAL OF ANIMAL SCIENCE, 90(8), 2639–2651.

By: R. Qiu n, J. Croom n, R. Ali n, A. Ballou n, C. Smith n, C. Ashwell n, H. Hassan n, C. Chiang, M. Koci n

Contributors: R. Qiu n, J. Croom n, R. Ali n, A. Ballou n, C. Smith n, C. Ashwell n, H. Hassan n, C. Chiang, M. Koci n

author keywords: broiler; direct fed microbials; energy metabolism; gene expression; probiotics; systemic immune function
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens / immunology; Chickens / metabolism; Diet / veterinary; Dietary Supplements; Energy Metabolism / immunology; Enzyme-Linked Immunosorbent Assay; Erythrocytes / immunology; Gene Expression Regulation / immunology; Gram-Positive Bacteria / physiology; Immunoglobulin A / blood; Immunoglobulin G / blood; Male; Oxygen Consumption; Sheep; Time Factors
TL;DR: Data indicate that supplementation with the direct fed microbial used in this study resulted in energy re-partitioning to the immune system and an increase in antibody production independent of changes in whole body metabolism or growth performance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Direct fed microbial supplementation repartitions host energy to the immune system

Journal of Animal Science, 90(8), 2639–2651.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2012 conference paper

Genome-wide methylation analysis of chicken primordial germ cells

Plant and Animal Genome XX Conference, January, 14–18.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

2012 article

Global Gene Expression Analysis of Long and Short Day 15 Bovine Conceptuses Produced In Vivo.

Oxford University Press.

By: C. Barnwell, C. Ashwell, P. Farin, W. Farmer & C. Farin

Source: ORCID
Added: February 4, 2021

2012 journal article

Physiological studies on the sex-linked dwarfism of the fowl: A review on the search for the gene's primary effect.

Asian Journal of Animal and Veterinary Advances, 11(9), 1785–1794.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2011 journal article

A Complex Genomic Rearrangement Involving the Endothelin 3 Locus Causes Dermal Hyperpigmentation in the Chicken

PLOS GENETICS, 7(12).

MeSH headings : Animals; Base Sequence; Breeding; Cell Proliferation; Chick Embryo; Chickens / genetics; Chickens / growth & development; Chromosome Mapping; Endothelin-3 / genetics; Feathers / growth & development; Gene Duplication; Gene Expression Regulation, Developmental; Gene Rearrangement; Genome; Melanocytes / cytology; Melanocytes / metabolism; Molecular Sequence Data; Mutation; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable; Skin Pigmentation / genetics
TL;DR: It is concluded that the same structural variant underlies this phenotype in all chicken breeds and this complex genomic rearrangement causing a specific monogenic trait in the chicken illustrates how novel mutations with major phenotypic effects have been reused during breed formation in domestic animals. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Differential expression of genes characterizing myofibre phenotype

ANIMAL GENETICS, 43(3), 298–308.

By: L. Nierobisz n, K. Sporer*, G. Strasburg*, K. Reed, S. Velleman*, C. Ashwell n, J. Felts n, P. Mozdziak n

Contributors: L. Nierobisz n, K. Sporer*, G. Strasburg*, K. Reed, S. Velleman*, C. Ashwell n, J. Felts n, P. Mozdziak n

author keywords: gene expression; microarray; muscle phenotype; turkey
MeSH headings : Age Factors; Animals; DNA, Complementary / genetics; Gene Expression Profiling; Gene Expression Regulation; Male; Meat; Muscle Fibers, Skeletal / metabolism; Muscle Proteins / genetics; Muscle Proteins / metabolism; Oligonucleotide Array Sequence Analysis; Phenotype; Real-Time Polymerase Chain Reaction; Turkeys / genetics; Turkeys / growth & development; Turkeys / metabolism
TL;DR: The gene analysis revealed that phenotypically 'red' BF muscle has high expression of glycolytic genes usually associated with the 'white' muscle phenotype, which may have large implications in muscle-type-related disorders and improvement of muscle quality in agricultural species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 conference paper

Bone development of three breed crosses of broilers is affected by incubation profiles

JOURNAL OF DAIRY SCIENCE, 93, 543–543.

Chris Ashwell

Event: ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA

Source: ORCID
Added: February 4, 2021

2010 journal article

Developmental Profile of Claudin-3,-5, and-16 Proteins in the Epithelium of Chick Intestine

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 293(7), 1175–1183.

By: O. Ozden*, B. Black n, C. Ashwell n, C. Tipsmark*, R. Borski n & B. Grubb n

author keywords: claudin proteins; tight junctions; intestine; goblet cells; chick embryo
MeSH headings : Animals; Chick Embryo; Chickens / genetics; Chickens / growth & development; Chickens / metabolism; Claudin-3; Claudins / analysis; Claudins / genetics; Claudins / metabolism; Immunohistochemistry; Intestinal Mucosa / embryology; Intestinal Mucosa / growth & development; Intestinal Mucosa / metabolism; Membrane Proteins / analysis; Membrane Proteins / genetics; Membrane Proteins / metabolism; RNA, Messenger / metabolism; Tight Junctions / chemistry; Tight Junctions / metabolism
TL;DR: Results of this work indicate that the claudin proteins assume their final locations within the epithelium around the time of hatching, suggesting that in addition to their known barrier and fence functions within tight junctions, these claudins may have additional roles in the differentiation and/or physiological function of chick intestine. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 conference paper

Early life nutritional conditioning with dietary phosphorus

JOURNAL OF DAIRY SCIENCE, 93, 216–216.

By: C. Ashwell & R. Angel

Event: ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA

Source: ORCID
Added: February 4, 2021

2010 journal article

Genomic Regions Associated with Dermal Hyperpigmentation, Polydactyly and Other Morphological Traits in the Silkie Chicken

JOURNAL OF HEREDITY, 101(3), 339–350.

By: B. Dorshorst n, R. Okimoto n & C. Ashwell n

author keywords: fibromelanosis; hyperpigmentation; inhibitor of dermal melanin; polydactyly; Silkie
MeSH headings : Animals; Chickens / abnormalities; Chickens / genetics; Chromosome Mapping; Crosses, Genetic; Female; Genome; Hedgehog Proteins / genetics; Male; Polydactyly / genetics; Polymorphism, Single Nucleotide; Regulatory Sequences, Nucleic Acid / genetics; Sequence Analysis, DNA; Skin Pigmentation / genetics
TL;DR: The primary focus of this study was to identify loci contributing to dermal pigmentation in the Silkie chicken, and loci associated with various other morphological traits segregating in these populations were also detected. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Genomic regions associated with antibody response to sheep red blood cells in the chicken

ANIMAL GENETICS, 42(3), 300–308.

By: B. Dorshorst n, P. Siegel* & C. Ashwell n

author keywords: association analysis; chicken; immune response; major histocompatibility complex; quantitative trait loci estimation; sheep red blood cells
MeSH headings : Animals; Antibodies / genetics; Antibodies / immunology; Antibody Formation; Body Weight; Chickens; Disease Susceptibility / immunology; Erythrocytes / immunology; Genetic Markers; Genetic Variation; Genome; Genome-Wide Association Study; Genotype; Haplotypes; Immunity, Innate; Immunization; Major Histocompatibility Complex / genetics; Major Histocompatibility Complex / immunology; Phenotype; Quantitative Trait Loci; Sheep
TL;DR: It is concluded that while these phenotypes are inversely correlated in the selected lines, they are controlled by distinct genetic loci and may be reflective of intense selection pressure on loci affecting the partitioning of nutrients between the immune system and growth pathways. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice.

Asian Journal of Agricultural Research, 6(3), 168–170.

By: T. Sopandi, E. Aksono H, R. Ahmed, S. Moushumi, H. Ahmed, M. Ali, H. Reza, W. Haq ...

Source: ORCID
Added: February 4, 2021

2010 journal article

Nutrigenomics for poultry--New tools for maximizing performance

Semantic Scholar.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

2010 journal article

Nutritional genomics: a practical approach by early life conditioning with dietary phosphorus

Revista Brasileira De Zootecnia, 39, 268–278.

By: C. Ashwell & R. Angel

Source: ORCID
Added: February 4, 2021

2010 conference paper

Testosterone exposure alters embryonic bursal gene expression in chicken lines selected for differential antibody response

JOURNAL OF DAIRY SCIENCE, 93, 544–544.

Chris Ashwell

Event: ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA

Source: ORCID
Added: February 4, 2021

2009 journal article

Genetic mapping of the sex-linked barring gene in the chicken

POULTRY SCIENCE, 88(9).

By: B. Dorshorst n & C. Ashwell n

author keywords: Barred Plymouth Rock; sex-linked barring; feather pigmentation; melanocyte
MeSH headings : Animals; Chickens / genetics; Chromosome Mapping / veterinary; Dose-Response Relationship, Drug; Feathers / physiology; Female; Genetic Linkage; Genetic Markers; Lymphoid Tissue / anatomy & histology; Male; Melanins / genetics; Organ Size; Phenotype; Sex Characteristics; Sex Chromosomes
TL;DR: The results indicate that further work directed at fine-mapping this region is necessary to identify this novel mechanism of melanocyte regulation, and suggests that several of these genes or their homologs are known to be involved in processes that could potentially explain the barring phenotype. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 article

Landmark contributions from the first one hundred years of Poultry Science Symposium: Introduction

Taylor, R. L., Jr., & Ashwell, C. M. (2009, April 1). POULTRY SCIENCE, Vol. 88, pp. 811–812.

By: R. Taylor* & C. Ashwell n

MeSH headings : Animals; Congresses as Topic; History, 20th Century; History, 21st Century; Poultry; Veterinary Medicine / history; Veterinary Medicine / standards
TL;DR: The paper provided a foundation for brain chemistry and brain development studies and further contributed to understanding gonadal development in photoperiod-ic birds through dissection of the neural pathways. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Landmark contributions from the first one hundred years of Poultry Science Symposium: Introduction

Poultry Science, 88(4), 811–812.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2009 journal article

Molecular, cellular, and developmental biology: Prehatch intestinal maturation of turkey embryos demonstrated through gene expression patterns

Poultry Science, 88, 2600–2609.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2009 conference paper

Nutritional epigenetics: Early life conditioning with dietary phosphorus

Proceedings of the... Mid-Atlantic Nutrition Conference.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

2009 journal article

Prehatch intestinal maturation of turkey embryos demonstrated through gene expression patterns

Poultry Science, 88(12), 2600–2609.

By: J. de Oliveira n, S. Druyan n, Z. Uni*, C. Ashwell n & P. Ferket n

author keywords: turkey embryo; intestinal development; gene expression; microarray
MeSH headings : Animals; Gene Expression Profiling; Gene Expression Regulation, Developmental / physiology; Intestinal Mucosa / metabolism; Intestines / embryology; Microvilli / metabolism; Oligonucleotide Array Sequence Analysis / veterinary; Symporters / metabolism; Turkeys / embryology
TL;DR: It is concluded that at hatch, poults should have the capacity to digest disaccharides but not oligopeptides, due to increased expression of sucrase-isomaltase but decreased expression of aminopeptidases and absorb monosaccharide and small peptides due to high expression of sodium-glucose cotransporter-4 and peptide transporter-1. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Prehatch intestinal maturation of turkey embryos demonstrated through gene expression patterns

Poultry Science, 88(12), 2600–2609.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2009 journal article

The effects of intra-amnionic feeding of arginine and/or ß-hyroxy-ß-methylbutyrate on jejunal gene expression in the turkey embryo and hatchling

International Journal of Poultry Science, 8(5), 437–445.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2008 conference paper

Dietary conditioning results in enduring effects on gene expression

WORLD’S POULTRY CONGRESS, 23.

By: C. Ashwell & R. Angel

Source: ORCID
Added: February 4, 2021

2008 conference paper

Dietary conditioning results in improved phosphorus utilization

World’s Poultry Congress 2008: Brisbane Proceedings; June 29--July, 4.

By: R. Angel & C. Ashwell

Source: ORCID
Added: February 4, 2021

2008 conference paper

Effect of in ovo feeding on turkey embryo intestinal morphology

POULTRY SCIENCE, 87, 31–31.

Chris Ashwell

Event: POULTRY SCIENCE ASSOC INC 1111 N DUNLAP AVE, SAVOY, IL 61874-9604 USA

Source: ORCID
Added: February 4, 2021

2008 journal article

Focused Microarrays as a Method to Evaluate Subtle Changes in Gene Expression

POULTRY SCIENCE, 87(11), 2418–2429.

By: S. Druyan n, J. Oliveira n & C. Ashwell n

author keywords: bioinformatics; microarray analysis; gene expression; embryonic development
MeSH headings : Animals; Chick Embryo / physiology; Chickens / genetics; DNA Primers; Embryo, Nonmammalian / physiology; Embryonic Development / genetics; Enzymes / genetics; Gene Expression; Genome; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis / methods; Proteins / genetics; RNA / genetics; RNA / isolation & purification
TL;DR: A focused 70-mer oligonucleotide microarray was developed to address the apparent limits of detection and issues with multiple testing resulting from the use of microarrays that include only a single spot (probe) for each gene, with detection of significant changes in gene expression of +/-7%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Focused microarrays as a method to evaluate subtle changes in gene expression

Poultry Science, 87(11), 2418–2429.

By: S. Druyan, J. De Oliveira & C. Ashwell

Source: ORCID
Added: February 4, 2021

2007 conference paper

Changes in the late term turkey embryo metabolism due to in ovo feeding

JOURNAL OF DAIRY SCIENCE, 90, 214–214.

Chris Ashwell

Event: AMER DAIRY SCIENCE ASSOC 1111 N DUNLAP AVE, SAVOY, IL 61874 USA

Source: ORCID
Added: February 4, 2021

2007 journal article

Characterization of the chicken small intestine type IIb sodium phosphate cotransporter

POULTRY SCIENCE, 86(1), 67–76.

By: F. Yan*, R. Angel* & C. Ashwell*

author keywords: phosphate; transporter; cloning; small intestine; chicken
MeSH headings : Amino Acid Sequence; Animal Feed; Animals; Base Sequence; Chickens / genetics; Chickens / metabolism; Cloning, Molecular; Diet / veterinary; Gene Expression Regulation; Genome; Intestine, Small / cytology; Intestine, Small / metabolism; Molecular Sequence Data; Phosphorus, Dietary / metabolism; Phosphorus, Dietary / pharmacology; Quantitative Trait Loci; Sodium-Phosphate Cotransporter Proteins, Type IIb / chemistry; Sodium-Phosphate Cotransporter Proteins, Type IIb / genetics; Sodium-Phosphate Cotransporter Proteins, Type IIb / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Dietary iron deficiency compromises normal development of elastic fibers in the aorta and lungs of chicks

JOURNAL OF NUTRITION, 137(8), 1895–1900.

By: C. Hill n, C. Ashwell*, S. Nolin n, F. Keeley*, C. Billingham*, A. Hinek*, B. Starcher*

MeSH headings : Animal Feed / analysis; Animals; Aorta / drug effects; Aorta / growth & development; Aorta / ultrastructure; Body Weight / drug effects; Chickens / metabolism; Diet; Elastic Tissue / drug effects; Elastic Tissue / growth & development; Iron Deficiencies; Iron, Dietary / administration & dosage; Iron, Dietary / metabolism; Lung / drug effects; Lung / growth & development; Lung / ultrastructure
TL;DR: The studies indicate that iron deficiency had a pronounced negative effect on elastic fiber development and suggests that fibrillin may have an important role in this pathology. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

ENVIRONMENT, WELL-BEING, AND BEHAVIOR

Poultry Science, 86, 15–20.

By: W. Awad, . Aschenbach, F. Setyabudi, E. Razzazi-Fazeli, J. Böhm & J. Zentek

Source: ORCID
Added: February 4, 2021

2007 journal article

Effect of dietary gelatin supplementation on the expression of selected enterocyte genes, intestinal development and early chick performance

Int J Poult Sci, 6, 944–951.

By: Y. Fasina, E. Moran, C. Ashwell, D. Conner, M. Leslie & . Mckee

Source: ORCID
Added: February 4, 2021

2007 journal article

Genome-Wide Linkage Analysis to Identify Chromosomal Regions Affecting Phenotypic Traits in the Chicken. II. Body Composition

Poultry Science, 86(2), 267.

By: H. Zhou, C. Evock-Clover, J. McMurtry, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2007 journal article

Genome-wide linkage analysis to identify chromosomal regions affecting phenotypic traits in the chicken. III. Skeletal integrity

Poultry Science, 86(2), 255–266.

By: H. Zhou, N. Deeb, C. Evock-Clover, A. Mitchell, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2007 journal article

Genome-wide linkage analysis to identify chromosomal regions affecting phenotypic traits in the chicken. IV. Metabolic traits

Poultry Science, 86(2), 267–276.

By: H. Zhou, C. Evock-Clover, J. McMurtry, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2007 journal article

Identification and characterization of a polymorphic mono-nucleotide microsatellite within 16S rRNA gene in chicken mitochondrial genome.

Asian Journal of Animal and Veterinary Advances, 6(8), 1195–1199.

By: J. Yin, S. Zeng, Y. Luo, J. Han, C. Amirinia, H. Emrani, M. Arbabe, R. Torshizi ...

Source: ORCID
Added: February 4, 2021

2007 conference paper

Improved phosphorus utilization in broilers fed phosphorus deficient diets early in life

JOURNAL OF DAIRY SCIENCE, 90, 72–73.

By: R. Angel & C. Ashwell

Event: AMER DAIRY SCIENCE ASSOC 1111 N DUNLAP AVE, SAVOY, IL 61874 USA

Source: ORCID
Added: February 4, 2021

2007 conference paper

Long-term effects on the expression of the intestinal Na-P type IIb cotransporter in broilers fed phosphorus deficient diets early in life

JOURNAL OF DAIRY SCIENCE, 90, 481–481.

By: C. Ashwell & R. Angel

Event: AMER DAIRY SCIENCE ASSOC 1111 N DUNLAP AVE, SAVOY, IL 61874 USA

Source: ORCID
Added: February 4, 2021

2007 journal article

Single strand conformation polymorphism in intron I of the chicken apoVLDL-II gene, and its relationship with triglyceride and very low density lipoprotein concentrations.

International Journal of Poultry Science, 16(11), pp-5.

By: A. Furqon, A. Gunawan, N. Ulupi, T. Suryati, C. Sumantri, S. Sulandari, M. Zein, S. Paryanti ...

Source: ORCID
Added: February 4, 2021

2007 conference paper

The expression patterns of HIF 1 alpha, HYOU1, HO1, and cTnT during embryonic development in the chicken heart

JOURNAL OF DAIRY SCIENCE, 90, 224–224.

By: S. Druyan, A. Cahaner & C. Ashwell

Event: AMER DAIRY SCIENCE ASSOC 1111 N DUNLAP AVE, SAVOY, IL 61874 USA

Source: ORCID
Added: February 4, 2021

2007 journal article

The expression patterns of hypoxia-inducing factor subunit alpha-1, heme oxygenase, hypoxia upregulated protein 1, and cardiac troponin T during development of the chicken heart

POULTRY SCIENCE, 86(11), 2384–2389.

By: S. Druyan n, A. Cahaner* & C. Ashwell n

author keywords: hypoxia; gene expression; embryonic development
MeSH headings : Animals; Chick Embryo; Gene Expression Regulation, Developmental; HSP70 Heat-Shock Proteins; Heart / embryology; Heme Oxygenase (Decyclizing) / genetics; Heme Oxygenase (Decyclizing) / metabolism; Hypoxia-Inducible Factor 1 / genetics; Hypoxia-Inducible Factor 1 / metabolism; Myocardium / metabolism; Oxygen Consumption; Proteins / genetics; Proteins / metabolism; Troponin T / genetics; Troponin T / metabolism
TL;DR: It appears that tissue Hypoxia is likely a normal component of embryonic development in the chicken based on the upregulation of hypoxia response genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 conference paper

Transcript profiling of testes from boars divergently selected for testosterone production

JOURNAL OF DAIRY SCIENCE, 90, 652–652.

By: M. Ashwell, S. Druyan, C. Ashwell & J. Cassady

Event: AMER DAIRY SCIENCE ASSOC 1111 N DUNLAP AVE, SAVOY, IL 61874 USA

Source: ORCID
Added: February 4, 2021

2006 conference paper

Assessing liver energy metabolism of late term turkey embryos using microarrays

POULTRY SCIENCE, 85, 35–35.

By: J. Oliveira, P. Ferket, C. Ashwell & Z. Uni

Event: POULTRY SCIENCE ASSOC INC 1111 N DUNLAP AVE, SAVOY, IL 61874-9604 USA

Source: ORCID
Added: February 4, 2021

2006 journal article

CA125 expression in spontaneous ovarian adenocarcinomas from laying hens

Gynecologic Oncology, 104(1), 192–198.

By: E. Jackson, K. Anderson*, C. Ashwell*, J. Petitte* & P. Mozdziak*

Contributors: E. Jackson, K. Anderson*, C. Ashwell*, J. Petitte* & P. Mozdziak*

author keywords: ovarian cancer; chicken; avian; cancer markers; in vitro; Western blotting
MeSH headings : Adenocarcinoma / pathology; Animals; Blotting, Western; CA-125 Antigen / biosynthesis; Cell Growth Processes / physiology; Chickens; Disease Models, Animal; Female; Immunohistochemistry; Ovarian Neoplasms / immunology; Ovarian Neoplasms / pathology
TL;DR: The growth of avian tumors in culture fits a sigmoidal curve for cell growth and suggests a cell cycle time of 28 h, and CA125 expression does not appear to change with time in culture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: January 2, 2020

2006 conference paper

CHICKEN MICROSATELLITE REPEATS: JUNGLE FOWL VS COMMERCIAL BIRDS

Plant and Animal Genome VX Conference Abstracts, (P561-241).

By: A. Kuo, J. Fulton, C. Clover, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2006 journal article

ENVIRONMENT, WELL-BEING, AND BEHAVIOR

Poultry Science, 85, 1123–1128.

By: J. McReynolds, R. Moore, L. Kubena, J. Byrd, C. Woodward, D. Nisbet, S. Ricke

Source: ORCID
Added: February 4, 2021

2006 conference paper

Effect of dietary gelatin supplementation on early intestinal development and performance of broiler chicks

POULTRY SCIENCE, 85, 36–36.

By: Y. Fasina, E. Moran, C. Ashwell, D. Conner & . Mckee

Event: POULTRY SCIENCE ASSOC INC 1111 N DUNLAP AVE, SAVOY, IL 61874-9604 USA

Source: ORCID
Added: February 4, 2021

2006 conference paper

Functional genomics: the beginning of a new age in nutrition research.

Nutritional biotechnology in the feed and food industries: Proceedings of Alltech's 22nd Annual Symposium, Lexington, Kentucky, USA, 23-26 April 2006, 199–205.

By: C. Ashwell & others

Event: Alltech UK

Source: ORCID
Added: February 4, 2021

2006 journal article

Genome-wide linkage analysis to identify chromosomal regions affecting phenotypic traits in the chicken. I. Growth and average daily gain

Poultry Science, 85(10), 1700–1711.

By: H. Zhou, N. Deeb, C. Evock-Clover, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2006 journal article

Genome-wide linkage analysis to identify chromosomal regions affecting phenotypic traits in the chicken. II. Body composition

Poultry Science, 85(10), 1712–1721.

By: H. Zhou, N. Deeb, C. Evock-Clover, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2006 journal article

Genome-wide linkage analysis to identify chromosomal regions affecting phenotypic traits in the chicken. II. Body composition.

International Journal of Poultry Science, 11(11), 121–127.

By: A. Fouad, H. El-Senousey, X. Yang, J. Yao, S. Abdukalykova, C. Ruiz-Feria, S. Abdukalykova, X. Zhao ...

Source: ORCID
Added: February 4, 2021

2006 article

IDENTIFICATION OF 876 NEW MICROSATELLITE MARKERS BY USING CHICKEN GENOME SEQUENCES

Cold Spring Harbor Press, Vol. 18. Cold Spring Harbor Press Abstract.

By: A. Kuo, J. Fulton, C. Clover, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2006 journal article

Integration of microsatellite-based genetic maps for the turkey (Meleagris gallopavo)

GENOME, 49(10), 1308–1318.

By: K. Reed n, L. Chaves n, T. Knutson n, S. Krueth n, C. Ashwell n & D. Burt n

author keywords: genetic mapping; Meleagris gallopavo; microsatellite
MeSH headings : Animals; Chickens / genetics; Chromosome Mapping; Computational Biology; Genetic Linkage; Genetic Markers; Genome / genetics; Microsatellite Repeats / genetics; Polymorphism, Genetic; Sequence Alignment; Turkeys / genetics
TL;DR: With the addition of the markers from the Roslin map, 438 markers are now genetically linked in the UMN/NTBF families, and more than 1700 turkey sequences have now been assigned to likely positions in the chicken-genome sequence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 conference paper

Microarray gene expression of breast muscle from chickens red low crude protein diets

POULTRY SCIENCE, 85, 172–172.

By: C. Ashwell, E. Oviedo-Rondon, S. Clemente-Hernandez & F. Salvador

Event: POULTRY SCIENCE ASSOC INC 1111 N DUNLAP AVE, SAVOY, IL 61874-9604 USA

Source: ORCID
Added: February 4, 2021

2006 journal article

Molecular genotype identification of the Gallus gallus major histocompatibility complex

IMMUNOGENETICS, 58(5-6), 407–421.

By: J. Fulton*, H. Juul-Madsen*, C. Ashwell n, A. McCarron*, J. Arthur*, . Neil P. O'Sullivan, R. Taylor*

author keywords: chicken MHC; molecular identification; MHC haplotype; microsatellite; genotype sequence
MeSH headings : Alleles; Animals; Chickens / genetics; Chickens / immunology; Gene Frequency; Genotype; Histocompatibility Antigens / classification; Histocompatibility Antigens / genetics; Major Histocompatibility Complex / genetics; Molecular Sequence Data; Phylogeny
TL;DR: Typing with LEI0258 and MCW0371 will be useful in identifying MHC haplotypes in outbred populations of chickens particularly for the initial development of serological reagents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Rapid aerosol transmission of Salmonella among turkeys in a simulated holding-shed environment

Poultry Science, 85(10), 1693–1699.

By: E. Harbaugh, D. Trampel, I. Wesley, S. Hoff, R. Griffith & H. Hurd

Source: ORCID
Added: February 4, 2021

2006 journal article

The relationship of body composition, feed intake, and metabolic hormones for broiler breeder females

POULTRY SCIENCE, 85(7), 1173–1184.

By: J. Sun*, M. Richards*, R. Rosebrough*, C. Ashwell n, J. McMurtry* & C. Coon*

author keywords: body composition; feed intake; metabolic hormone; broiler breeder
MeSH headings : Animal Feed / analysis; Animals; Body Composition / physiology; Chickens / physiology; Diet; Estradiol / metabolism; Feeding Behavior; Female; Glucagon / metabolism; Insulin / metabolism; Insulin-Like Growth Factor I / metabolism; Insulin-Like Growth Factor II / metabolism; Leptin / metabolism; Light; Organ Size; Ovary / physiology; Oviposition / physiology; Thyroid Hormones
TL;DR: Stepwise regressions for predicting percentage carcass protein for breeders fed by both systems shows that T3 and IGF-I concentrations were the most important for ad libitum-fed breeders, whereas IGF-II and T4 were best for feed-restricted breeders. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Assignment of 42 Microsatellite Markers from Chromosome 28 on Chicken Genome (Genbank Bv 680436-Bv680477)

Genbank.

By: A. Kuo, J. Fulton & C. Ashwell

Source: ORCID
Added: February 4, 2021

2005 journal article

Chicken quantitative trait loci for growth and body composition associated with the very low density apolipoprotein-II gene

Poultry Science, 84(5), 697–703.

By: H. Li, N. Deeb, H. Zhou, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2005 journal article

Dietary metformin effects on in vitro and in vivo metabolism in the chicken

Nutrition Research, 25(5), 491–497.

By: R. Rosebrough* & C. Ashwell*

author keywords: biguanides; blood glucose; appetite; metabolism; chicken
TL;DR: The increase in plasma lactic acid suggests that MET stimulates pyruvate kinase in the chicken, as it does in mammals, and may explain MET's ability to reduce hepatic triglyceride synthesis and suppress appetite. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020

2005 journal article

ENVIRONMENT, WELL-BEING, AND BEHAVIOR

Poultry Science, 84, 185–193.

By: C. Woodward, Y. Kwon, L. Kubena, J. Byrd, R. Moore, D. Nisbet, S. Ricke

Source: ORCID
Added: February 4, 2021

2005 journal article

ENVIRONMENT, WELL-BEING, AND BEHAVIOR

Poultry Science, 84, 679–686.

By: J. Do, I. Choi & K. Nahm

Source: ORCID
Added: February 4, 2021

2005 journal article

Effects of chemically amended litter on broiler performances, atmospheric ammonia concentration, and phosphorus solubility in litter

Poultry Science, 84(5), 679–686.

By: J. Do, I. Choi & K. Nahm

Source: ORCID
Added: February 4, 2021

2005 journal article

Environmental and management factors affecting the welfare of chickens on commercial farms in the United Kingdom and Denmark stocked at five densities

Poultry Science, 84(8), 1155–1165.

By: T. Jones, C. Donnelly & M. Stamp Dawkins

Source: ORCID
Added: February 4, 2021

2005 journal article

Evaluation of the broiler’s ability to adapt to an early moderate deficiency of phosphorus and calcium

Poultry Science, 84(8), 1232–1241.

By: F. Yan, R. Angel, C. Ashwell, A. Mitchell & M. Christman

Source: ORCID
Added: February 4, 2021

2005 journal article

Expressed sequence tag analysis of Eimeria-stimulated intestinal intraepithelial lymphocytes in chickens

Molecular Biotechnology, 30(2), 143–149.

By: W. Min, H. Lillehoj, C. Ashwell, C. Van Tassell, R. Dalloul, L. Matukumalli, J. Han, E. Lillehoj

Source: ORCID
Added: February 4, 2021

2005 conference paper

GENOME-WIDE LINKAGE AND QTL MAPPING IN CHICKEN F2 POPULATIONS

Plant and Animal Genome VX Conference Abstracts, 209.

By: H. Zhou, N. Deeb, C. Evock-Clover, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2005 journal article

Insulin-like growth factor-I gene polymorphism associations with growth, body composition, skeleton integrity, and metabolic traits in chickens

Poultry Science, 84(2), 212–219.

By: H. Zhou, A. Mitchell, J. McMurtry, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2005 journal article

Interactions among endocrine, nutritional and genetic factors controlling metabolism in the broiler

Avian and Poultry Biology Reviews, 16(2), 95–100.

By: R. Rosebrough, J. McMurtry, M. Richards, A. Mitchell, T. Ramsay & C. Ashwell

Source: ORCID
Added: February 4, 2021

2005 journal article

MICROSATELLITE MARKERS FROM CHROMOSOME 27 BY USING THE CHICKEN GENOME SEQUENCE (GENBANK BV680374-BV680405)

Genbank.

By: A. Kuo, J. Fulton & C. Ashwell

Source: ORCID
Added: February 4, 2021

2005 conference paper

USING CHICKEN GENOME SEQUENCES TO SEARCH FOR NEW MICROSATELLITE BIOMARKERS

Plant and Animal Genome VX Conference Abstracts, 206.

By: A. Kuo, J. Fulton & C. Ashwell

Source: ORCID
Added: February 4, 2021

2005 conference paper

Use of biotechnology in nutrition research

CAROLINA POULTRY NUTRITION CONFERENCE, 32, 107–116.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

2005 journal article

changes in the efficiency of muscular contraction under pressure

Journal of Cellular and Comparative Physiology.

By: O. Ozden, B. Black, C. Ashwell, C. Tipsmark, R. Borski & others

Source: ORCID
Added: February 4, 2021

2004 conference paper

ASSOCIATIONS OF SINGLE NUCLEOTIDE POLYMORPHISM IN INSULIN-LIKE GROWTH FACTOR 1 GENE WITH GROWTH, BODY COMPOSITION, SKELETON INTEGRITY, AND METABOLIC TRAITS IN CHICKENS

World Poultry, 1–4.

By: H. Zhou, A. Mitchell, J. Mcmurtry, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2004 conference paper

Analysis of Expressed Sequence Tags (Est) Cdna Library from Eimeria-Activated Intestinal Intra-Epithelial Lymphocytes

Avian Immunology Group Meeting, 60.

By: H. Lillehoj, W. Min, C. Ashwell & C. Van Tassell

Source: ORCID
Added: February 4, 2021

2004 journal article

Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms.

Asian Journal of Poultry Science, 10(3), 123–128.

By: C. Supakorn, S. Wattanachant, S. Benjakul, D. Ledward, N. Dorji, M. Daungjinda, Y. Phasuk, N. Dorji ...

Source: ORCID
Added: February 4, 2021

2004 conference paper

Molecular cloning and characterization of a broiler small intestine Type IIb sodium phosphate cotransporter gene

JOURNAL OF DAIRY SCIENCE, 87, 263–263.

By: F. Yan, C. Ashwell & R. Angel

Event: AMER DAIRY SCIENCE ASSOC 1111 N DUNLAP AVE, SAVOY, IL 61874 USA

Source: ORCID
Added: February 4, 2021

2004 conference paper

Molecular genotype identification of the chicken major histocompatibility complex

Proc. International Conference on Animal Genetics, Tokyo, Japan, 59.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2004 journal article

Plasma clearance and tissue distribution of radiolabeled leptin in the chicken

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 138(1), 27–32.

By: J. McMurtry*, C. Ashwell*, D. Brocht* & T. Caperna*

author keywords: binding proteins; food intake; hormone; receptor
MeSH headings : Animals; Chickens; Iodine Radioisotopes / pharmacokinetics; Leptin / blood; Leptin / pharmacokinetics; Male; Receptors, Cell Surface / blood; Receptors, Leptin; Tissue Distribution; Trichloroacetic Acid / analysis; Trichloroacetic Acid / metabolism
TL;DR: It is concluded that unlike mammals, no circulating leptin binding protein is present in chickens and leptin is metabolized and cleared very rapidly from blood by the kidney. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020

2003 journal article

Association of Bmp Genes with Skeletal Integrity in Chickens

Poultry Science, 82(Suppl 1), 23.

By: H. Zhou, N. Deeb, A. Mitchell, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2003 journal article

Chicken quantitative trait loci for growth and body composition associated with transforming growth factor-beta genes

Poultry Science, 82(3), 347–356.

By: H. Li, N. Deeb, H. Zhou, A. Mitchell, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2003 journal article

Development of mucoadhesive patches for buccal administration of ibuprofen.

International Journal of Pharmacology, 8(5), 331–336.

By: A. Behra, T. Kumar Giri, D. Krishna Tripathi, A. Alexander, M. Abdollahi, A. Bahreini-Moghadam, B. Emami, F. Fooladian ...

Source: ORCID
Added: February 4, 2021

2003 journal article

Estimation of genetic parameters for fat deposition and carcass traits in broilers.

Pakistan Journal of Biological Sciences, 12(1), pp-1.

By: S. Zerehdaran, S. Hassani, A. Gharebash, A. Khanahmadi, F. Farivar, J. Arthur, G. Albers, W. Bessei ...

Source: ORCID
Added: February 4, 2021

2003 journal article

Expression of selected genes related to lipid metabolism in broiler breeder chickens

Journal of Nutrition, 133, 707–715.

By: M. Richards, S. Poch, C. Coon, R. Rosebrough, C. Ashwell & J. McMurty

Source: ORCID
Added: February 4, 2021

2003 journal article

Feed restriction significantly alters lipogenic gene expression in broiler breeder chickens

The Journal of Nutrition, 133(3), 707–715.

By: M. Richards, S. Poch, C. Coon, R. Rosebrough, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2003 journal article

Ghrelin Gene Sequence and Expression in Lines of Chickens Selected for High and Low Body Weight

Poultry Science, 82(Suppl 1), 62.

By: A. Kuo, V. Blacksburg, C. Ashwell, M. Richards, S. Poch, P. Siegel, V. Blacksburg, D. Denbow, V. Blacksburg

Source: ORCID
Added: February 4, 2021

2003 journal article

Hypoglycemia and reduced feed intake in broiler chickens treated with metformin

Poultry Science, 82(1), 106–110.

By: C. Ashwell & J. Mcmurtry

Source: ORCID
Added: February 4, 2021

2003 journal article

Nutrient-Gene Interactions

J. Nutr, 133, 707–715.

By: M. Richards, S. Poch, C. Coon, R. Rosebrough, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2003 journal article

The development of homologous radioimmunoassay for chicken leptin

Poult. Sci, 82(Suppl 1), 84.

By: J. McMurtry, D. Brocht, C. Ashwell, P. Allen, R. Leach & C. Coon

Source: ORCID
Added: February 4, 2021

2002 conference paper

Chicken QTLs for growth, body composition, and metabolic factors associated with TGF-beta family genes

Abstract of a poster presented at the Plant, Animal and Microbe Genomes X Conference.

By: H. Li, N. Deeb, H. Zhou, C. Ashwell & S. Lamont

Source: ORCID
Added: February 4, 2021

2002 conference paper

Endocrine and metabolic factors in unique inbred$\times$ outbred chicken crosses

7th World Congress on Genetics Applied to Livestock Production, Montpellier, France.

By: C. Ashwell, J. McMurtry, N. Deeb & S. Lamont

Source: ORCID
Added: February 4, 2021

2002 journal article

Endocrine and metabolite adaptations in the thermoconditioned chicken in response to high ambient température

Poultry Sci, 81, 214.

By: J. Mc Murtry, S. Yahav, D. Brocht, C. Ashwell, R. Rosebrough, S. Kahl, . Leach

Source: ORCID
Added: February 4, 2021

2002 journal article

Expression of an uncoupling protein gene homolog in chickens

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 133(2), 345–358.

By: C. Evock-Clover, S. Poch, M. Richards, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2001 journal article

Identification and expression of the turkey leptin receptor gene

Poult. Sci, 80, 394.

By: M. Richards, S. Poch & C. Ashwell

Source: ORCID
Added: February 4, 2021

2001 journal article

Isolation, characterization and mapping of the bovine signal peptidase subunit 18 gene

Animal Genetics, 32(4), 232–233.

By: M. Ashwell, C. Ashwell, W. Garrett & G. Bennett

Source: ORCID
Added: February 4, 2021

2001 conference paper

Leptin receptor gene expression in turkeys

FASEB JOURNAL, 15(5), A961–A961.

By: M. Richards, S. Poch & C. Ashwell

Event: FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA

Source: ORCID
Added: February 4, 2021

2001 journal article

Leptin: molecular biology and physiology

Avian Endocrinology. Narosa Publishing House, New Delhi, India, 317–328.

By: J. McMurtry, C. Ashwell, M. Richards & R. Vasilatos-Younken

Source: ORCID
Added: February 4, 2021

2001 journal article

The ontogeny of leptin mRNA expression in growing broilers and its relationship to metabolic body weight

Domestic Animal Endocrinology, 21(3), 161–168.

By: C. Ashwell, M. Richards & J. McMurtry

Source: ORCID
Added: February 4, 2021

2000 journal article

Design and application of a polyclonal peptide antiserum for the universal detection of leptin protein

Journal of Biochemical and Biophysical Methods, 45(2), 147–156.

By: M. Richards, T. Caperna, T. Elsasser, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2000 journal article

Leptin-induced decrease in food intake in chickens

Physiology & Behavior, 69(3), 359–362.

By: D. Denbow, S. Meade, A. Robertson, J. McMurtry, M. Richards & C. Ashwell

Source: ORCID
Added: February 4, 2021

2000 journal article

PROTEIN SYNTHESIS, POST-TRANSLATION MODIFICATION, AND DEGRADATION-The role of the membrane-spanning domain of type I signal peptidases in substrate cleavage site selection.

Journal of Biological Chemistry, 275(49), 38813–38822.

By: J. Carlos, M. Paetzel, G. Brubaker, A. Karla, C. Ashwell, M. Lively, G. Cao, P. Bullinger, R. Dalbey

Source: ORCID
Added: February 4, 2021

2000 journal article

Quantitative analysis of leptin mRNA using competitive reverse transcription polymerase chain reaction and capillary electrophoresis with laser-induced fluorescence detection

ELECTROPHORESIS: An International Journal, 21(4), 792–798.

By: M. Richards, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

2000 journal article

The role of the membrane-spanning domain of type I signal peptidases in substrate cleavage site selection

Journal of Biological Chemistry, 275(49), 38813–38822.

By: J. Carlos, M. Paetzel, G. Brubaker, A. Karla, C. Ashwell, M. Lively, G. Cao, P. Bullinger, R. Dalbey

Source: ORCID
Added: February 4, 2021

1999 journal article

Analysis of leptin gene expression in chickens using reverse transcription polymerase chain reaction and capillary electrophoresis with laser-induced fluorescence detection

Journal of Chromatography A, 853(1-2), 321–335.

By: M. Richards, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

1999 journal article

Effects of growth hormone and pair-feeding on leptin mRNA expression in liver and adipose tissue

Domestic Animal Endocrinology, 17(1), 77–84.

By: C. Ashwell, J. McMurtry, X. Wang, Y. Zhou & R. Vasilatos-Younken

Source: ORCID
Added: February 4, 2021

1999 conference paper

First Diverless Subsea Wireline Well Intervention Performed in Offshore Vietnam offers Low-Cost Solution for Light Well Workovers: Case Histories and Future Trends

SPE Asia Pacific Oil and Gas Conference and Exhibition. Presented at the Society of Petroleum Engineers.

By: D. Larimore, C. Ashwell, A. Halim, Z. Abidin & others

Event: Society of Petroleum Engineers

Source: ORCID
Added: February 4, 2021

1999 journal article

Hormonal regulation of leptin expression in broiler chickens

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 276(1), R226–R232.

By: C. Ashwell, S. Czerwinski, D. Brocht & J. McMurtry

Source: ORCID
Added: February 4, 2021

1999 conference paper

Leptin expression patterns in embryonic development

FASEB JOURNAL, 13(4), A442–A442.

By: C. Ashwell, M. Richards, D. Brocht & J. McMurtry

Event: FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA

Source: ORCID
Added: February 4, 2021

1999 chapter

Signal peptidases

In Proteases New Perspectives (pp. 35–43). Birkhäuser, Basel.

By: M. Lively & C. Ashwell

Source: ORCID
Added: February 4, 2021

1998 journal article

Changes in body composition and adipocyte cellularity of male broilers subjected to varying degrees early-life feed restriction.

Asian Journal of Animal and Veterinary Advances, 3(4), 321–326.

By: K. Benyi, O. Acheampong-Boateng, D. Norris, M. Mikasi, O. Altan, S. Ozkan, S. Yakin, M. Appleby ...

Source: ORCID
Added: February 4, 2021

1998 journal article

Cloning of turkey insulin-like growth factor-I (IGF-I)

DNA Database.

By: S. Czerwinski, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

1998 journal article

EFFECTS OF GROWTH HORMONE AND PAIR-FEEDING ON LEPTIN mRNA EXPRESSION IN LIVER AND ADIPOSE TISSUE OF BROILER CHICKENS

BIOTECHNOLOGIE AGRONOMIE SOCIETE ET ENVIRONNEMENT, 2, 45–45.

By: C. Ashwell, J. McMurtry, X. Wang, Y. Zhou & R. Vasilatos-Younken

Source: ORCID
Added: February 4, 2021

1998 journal article

Investigations into the nature of signal peptidase substrate interactions.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

1998 journal article

Turkey leptin (ob) mRNA, partial cds

GenBank Accession Number AF082501.

By: C. Ashwell, S. Czerwinski & J. McMurtry

Source: ORCID
Added: February 4, 2021

1997 conference paper

Eukaryotic signal peptidase recognizes signal peptides asymmetrically

FASEB JOURNAL, 11(9), A1392–A1392.

By: C. Ashwell & M. Lively

Event: FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA

Source: ORCID
Added: February 4, 2021

1996 journal article

Brief-Offshore North-Sea Case-Histories of the Environmentally Friendly Testing Vessel, the Crystal-Sea

Journal of Petroleum Technology, 48(4), 324–325.

By: O. Tjelta, C. Ashwell, G. Hilmarsen, R. Taylor & others

Source: ORCID
Added: February 4, 2021

1996 conference paper

Probing the substrate binding site of signal peptidases with a synthetic signal peptide model containing a p-benzoyl-phenylalanine photoaffinity label.

FASEB JOURNAL, 10(6), 2343–2343.

By: C. Ashwell, J. Harp, R. Dalbey & M. Lively

Event: FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998

Source: ORCID
Added: February 4, 2021

1995 journal article

Nutrient requirements of laying hens.

International Journal of Poultry Science, 11(7), 261–270.

By: M. Reyes, C. Salas, C. Coon, Y. Attia, W. Burke, K. Yamani, L. Jensen, H. Boekholt ...

Source: ORCID
Added: February 4, 2021

1995 conference paper

Offshore Northern Sea Case Histories of the Environmentally Friendly Testing Vessel, the" Crystal Sea"

Offshore Technology Conference. Presented at the Offshore Technology Conference.

By: O. Tjelta, C. Ashwell, R. Taylor & others

Event: Offshore Technology Conference

Source: ORCID
Added: February 4, 2021

1995 report

The well testing vessel``Crystal Sea:``Cost effective alternative to flaring hydrocarbon into the atmosphere

American Society of Mechanical Engineers, New York, NY (United States).

By: C. Ashwell, S. Bringsli, R. Bullock & R. Taylor

Source: ORCID
Added: February 4, 2021

1994 conference paper

Development of gel systems for pipeline dewatering and drying applications

Offshore technology conference. Presented at the Offshore Technology Conference.

By: G. Schreurs, P. Burman, S. Hamid, C. Falck, J. Maribu, C. Ashwell, others

Event: Offshore Technology Conference

Source: ORCID
Added: February 4, 2021

1993 journal article

Characterization of the N-terminal region within the alkyl hydroperoxide reductase AhpF protein

Free Radical Biology and Medicine, 15(5), 506.

By: C. Ashwell & L. Poole

Source: ORCID
Added: February 4, 2021

1990 journal article

Effects of energy and protein allowances during lay on the reproductive performance of broiler breeder hens.

International Journal of Poultry Science, 10(12), pp-1.

By: M. Reyes, C. Salas, C. Coon, Y. Attia, W. Burke, K. Yamani, L. Jensen, D. Balnave ...

Source: ORCID
Added: February 4, 2021

1987 journal article

Genetic diversity of Chinese native chicken breeds based on protein polymorphism, randomly amplified polymorphic DNA and microsatellite polymorphism.

Pakistan Journal of Biological Sciences, 10(15), pp-1.

By: H. H. Musa, J. H. Cheng, W. B. Bao, B. C. Li, D. M. Mekki, G. H. Chen, F. Allendorf, N. Ryman ...

Source: ORCID
Added: February 4, 2021

1977 journal article

A new method for the direct determination of serum cholesterol.

Asian Journal of Poultry Science, 9(3), 1149–1149.

By: A. DSilva, C. DSouza, G. Bowers, R. McComb, M. Kelley, V. Bowes, R. Julian, T. Stirtzinger ...

Source: ORCID
Added: February 4, 2021

1916 journal article

Quantitative trait loci identified for blood chemistry components of an advanced intercross line of chickens under heat stress

By: M. Rothschild, C. Ashwell, M. Persia, S. Lamont, A. Van Goor & C. Schmidt

Source: ORCID
Added: February 4, 2021

journal article

2003 Poultry Science Author Index

Catena, 1050, 381.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

journal article

2009 Poultry Science Association Annual Meeting

Abbas, A. O., Abdou, A. M., Abi-Ghanem, D., Acar, N., Adedokun, S. A., Adejinmi, O. O., … others.

By: A. Abbas, A. Abdou, D. Abi-Ghanem, N. Acar, S. Adedokun, O. Adejinmi, Y. Adesiji, A. Adeyeye ...

Source: ORCID
Added: February 4, 2021

journal article

ANALYSIS OF LEPTIN GENE EXPRESSION IN CHICKENS USING RT-PCR AND CAPILLARY ELECTROPHORESIS WITH LASER-INDUCED FLURESCENCE DETECTION

Richards, M., Ashwell, C., & McMurtry, J. Journal of Chromatography.

By: M. Richards, C. Ashwell & J. McMurtry

Source: ORCID
Added: February 4, 2021

journal article

Genomics of heat stress in chickens SJ Lamont1, DJ Coble1, A. Bjorkquist1, MF Rothschild1, M. Persia1, C. Ashwell2 and C. Schmidt3

Lamont, S. J., Coble, D. J., Bjorkquist, A., Rothschild, M. F., Persia, M., Ashwell, C., & Schmidt, C.

By: S. Lamont, D. Coble, A. Bjorkquist, M. Rothschild, M. Persia, C. Ashwell, C. Schmidt

Source: ORCID
Added: February 4, 2021

journal article

INVITED CONTRIBUTIONS AND FOCUSED PRESENTATIONS

Siegel, P. B., Honaker, C. F., Dunn, I. C., Haberer, G., Wolc, A., Arango, J., … others.

By: P. Siegel, C. Honaker, I. Dunn, G. Haberer, A. Wolc, J. Arango, P. Settar, J. Fulton ...

Source: ORCID
Added: February 4, 2021

journal article

Immunology and Pathology: Poultry Immunology and Diseases

Chris Ashwell

Source: ORCID
Added: February 4, 2021

journal article

Prestage Department of Poultry Science North Carolina State University, Raleigh, NC, 27606

Lowman, Z. S., & Ashwell, C. M.

By: Z. Lowman & C. Ashwell

Source: ORCID
Added: February 4, 2021

journal article

The beginning of a new age in nutrition research

Ashwell, C. M.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

Employment

Updated: July 9th, 2024 21:39

2021 - present

West Virginia University Morgantown, West Virginia, US
School Director and Professor School of Agriculture and Food Systems

2003 - 2021

North Carolina State University Raleigh, NC, US
Professor Prestage Department of Poultry Science

Education

Updated: September 27th, 2019 12:36

1992 - 1997

Wake Forest University Winston-Salem, NC, US
PhD Biochemistry

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