Works (9)
Updated: April 5th, 2024 11:01
2024 journal article
Flunixin meglumine tissue residues after intravenous administration in goats
FRONTIERS IN VETERINARY SCIENCE, 10.
author keywords: flunixin; goat; residues; tolerance limit method; withdrawal interval; withdrawal time
TL;DR:
Since any detection of flunixin residues at slaughter found in goat tissues is considered a violative residue, a conservative withdrawal interval of 17 days was calculated to ensure levels of flunixin fell below the regulatory limits of detection in liver, kidney, and muscle tissues.
(via Semantic Scholar)
www.frontiersin.org (publisher PDF)
Sources: Web Of Science, NC State University Libraries
Added: February 12, 2024
2023 journal article
Milk residues following multiple doses of meloxicam and gabapentin in lactating dairy cattle
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261(12), 1873–1879.
author keywords: meloxicam; gabapentin; lactation; postpartum; dairy cattle
TL;DR:
Results of this study suggest that milk from cows treated with multiple doses of meloxicam alone or in combination with gabapentin will have low drug concentrations and falls below the reported limit of detection formeloxicam or gABapentin 120 and 60 hours respectively, following the final dose regardless of their stage of lactation.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 1, 2024
2021 journal article
EVALUATION OF THE PHARMACOKINETIC BEHAVIOR OF TULATHROMYCIN (DRAXXIN) IN FLORIDA MANATEES (TRICHECHUS MANATUS LATIROSTRIS) UNDERGOING MEDICAL REHABILITATION
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 52(3), 880–885.
MeSH headings : Animals; Animals, Wild; Cattle; Disaccharides; Heterocyclic Compounds; Horses; Swine; Trichechus; Trichechus manatus
TL;DR:
The pharmacokinetic behavior of tulathromycin in Florida manatees can be used to optimize dosage regimens in this species, and this antibiotic has also been used in manatee with positive clinical outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 2, 2021
2019 journal article
Comparative plasma and urine concentrations of flunixin and meloxicam in goats
SMALL RUMINANT RESEARCH, 174, 40–46.
TL;DR:
The information from this study represents a potential worst-case scenario for urine depletion and helps determine the withdrawal intervals needed for flunixin meglumine in show goats when administered in this extra label manner.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 4, 2019
2019 journal article
Impact of bovine respiratory disease on the pharmacokinetics of danofloxacin and tulathromycin in different ages of calves
PLOS ONE, 14(6).
Ed(s): D. Gladue
MeSH headings : Age Factors; Animals; Area Under Curve; Bronchoalveolar Lavage Fluid / chemistry; Cattle; Cattle Diseases / drug therapy; Disaccharides / administration & dosage; Disaccharides / pharmacokinetics; Extracellular Fluid / chemistry; Female; Fluoroquinolones / administration & dosage; Fluoroquinolones / pharmacokinetics; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / pharmacokinetics; Pasteurella Infections / drug therapy; Pasteurella Infections / veterinary; Pasteurella multocida / pathogenicity; Respiration Disorders / drug therapy; Respiration Disorders / veterinary
TL;DR:
Age was determined to be a significant covariate for calves administered danofloxacin and tulathromycin for plasma PK parameters and potential reasons for age-related differences on plasma concentration–time profiles and the impact of disease on the partitioning of the drug from the blood to the lungs and ISF as a function of age are explored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 30, 2019
2018 journal article
Effect of age on plasma protein binding of several veterinary drugs in dairy Check for calves 2
RESEARCH IN VETERINARY SCIENCE, 121, 59–64.
author keywords: Protein binding; Calves; Alpha-1-acid glycoprotein; Albumin
MeSH headings : Age Factors; Animals; Blood Proteins / metabolism; Cattle / metabolism; Protein Binding; Veterinary Drugs / metabolism
TL;DR:
Findings from these calves suggest that age is not an important factor in the binding of these drugs to plasma proteins, and statistically significant age-effects on plasma protein binding were not observed for any of the drugs evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 17, 2018
2018 journal article
Short communication: Use of an ultrafiltration device in gland cistern for continuous sampling of healthy and mastitic quarters of lactating cattle for pharmacokinetic modeling.
Journal of Dairy Science, 101(11), 10414–10420.
MeSH headings : Administration, Intravenous / veterinary; Animals; Cattle; Chromatography, High Pressure Liquid / veterinary; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Feasibility Studies; Female; Lactation; Mammary Glands, Animal / metabolism; Mass Spectrometry / veterinary; Mastitis, Bovine / diagnosis; Milk / chemistry; Ultrafiltration / veterinary
TL;DR:
Collection of ultrafiltration samples from the mammary gland of cows provides a viable means to continuously assess drug concentrations in the milk while continuing to milk the cow normally, and demonstrates the utility of continuous sampling of milk via ultraFiltration for future pharmacokinetic studies in cattle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: November 5, 2018
journal article
Comparative urine residues of flunixin and meloxicam in show goats
Bublitz, C. M., Mzyk, D. A., Mays, T., Fajt, V. R., Hairgrove, T., & Baynes, R. E. Journal of Veterinary Pharmacology and Therapeutics, 41, 24–24.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Impact of bovine respiratory disease on the pharmacokinetics of danofloxacin and tulathromycin in different ages of calves
Mzyk, D. A., Bublitz, C. M., Martinez, M. N., Davis, J. L., Baynes, R. E., & Smith, G. W. Journal of Veterinary Pharmacology and Therapeutics, 41, 33–33.
Source: NC State University Libraries
Added: August 6, 2018
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