Carly Marie Catella

College of Engineering

Works (4)

Updated: November 19th, 2025 16:13

2025 article

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

Catella, C. M., Sarma, S., Hinesley, C. M., Febo, C. E., Breau, K. A., Durmusoglu, D., … Crook, N. (2025, November 14). Biotechnology and Bioengineering.

By: C. Catella n, S. Sarma n, C. Hinesley *, C. Febo n, K. Breau *, D. Durmusoglu n, E. Purnell n, S. Magness* ...

topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Helicobacter pylori-related gastroenterology studies; Yersinia bacterium, plague, ectoparasites research
Sources: NC State University Libraries, NC State University Libraries
Added: November 16, 2025

2023 article

Design of 8-mer peptides that block Clostridioides difficile toxin A in intestinal cells

Sarma, S., Catella, C. M., Pedro, E. T. S., Xiao, X., Durmusoglu, D., Menegatti, S., … Hall, C. K. (2023, August 26). Communications Biology, Vol. 6.

By: S. Sarma n, C. Catella n, E. Pedro*, X. Xiao n, D. Durmusoglu n, S. Menegatti n , N. Crook n , S. Magness*, C. Hall n 

topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Microscopic Colitis; Toxin Mechanisms and Immunotoxins
TL;DR: An approach that combines a Pep tide B inding D esign (PepBD) algorithm, molecular-level simulations, a rapid screening assay, and surface plasmon resonance (SPR) measurements to develop peptide inhibitors that block Toxin A in colon epithelial cells is described. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 27, 2023

2021 article

Design and in situ biosynthesis of precision therapies against gastrointestinal pathogens

Durmusoglu, D., Catella, C. M., Purnell, E. F., Menegatti, S., & Crook, N. C. (2021, July 1). Current Opinion in Physiology, Vol. 10.

By: D. Durmusoglu n, C. Catella n, E. Purnell n, S. Menegatti n  & N. Crook n 

topics (OpenAlex): Antimicrobial Peptides and Activities; Probiotics and Fermented Foods; Antifungal resistance and susceptibility
TL;DR: Recent progress in understanding of small molecules that inhibit specific virulence mechanisms point to an emerging integrative approach to treatment of gastrointestinal diseases, comprising microbiologists, peptide chemists, and synthetic biologists. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 26, 2021

2020 article

Peptides and pseudopeptide ligands: a powerful toolbox for the affinity purification of current and next-generation biotherapeutics

Chu, W., Prodromou, R., Day, K. N., Schneible, J. D., Bacon, K. B., Bowen, J. D., … Menegatti, S. (2020, October 23). Journal of Chromatography A, Vol. 1635.

By: W. Chu n, R. Prodromou n, K. Day n, J. Schneible n, K. Bacon n, J. Bowen n, R. Kilgore n, C. Catella n ...

author keywords: Affinity ligands; peptides; peptoids; pseudopeptides; biotherapeutics
MeSH headings : Antibodies / isolation & purification; Biological Products / isolation & purification; Chemistry, Pharmaceutical / methods; Chromatography, Affinity; Family Characteristics; Humans; Ligands; Peptides / isolation & purification; Peptoids / chemistry; Proteins / isolation & purification
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; Chemical Synthesis and Analysis; Click Chemistry and Applications
TL;DR: This work presents a comprehensive and systematic review of the literature on peptide-based ligands and their use in the affinity purification of established and upcoming biological drugs. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: January 25, 2021

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