Christopher Dekaney

Sheahan, B. J., Theriot, C. M., Cortes, J. E., & Dekaney, C. M. (2022). Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells. GUT MICROBES, 14(1). https://doi.org/10.1080/19490976.2021.2018898

Sheahan, B. J., Freeman, A. N., Keeley, T. M., Samuelson, L. C., Roper, J., Hasapis, S., … Dekaney, C. M. (2021). Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 12(1), 119–140. https://doi.org/10.1016/j.jcmgh.2021.01.015

Dekaney, C. M. (2021). Hyperproliferation of the Intestinal Epithelium. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, Vol. 12, pp. 1145–1146. https://doi.org/10.1016/j.jcmgh.2021.06.010

Shanahan, M. T., Kanke, M., Oyesola, O. O., Hung, Y.-H., Koch-Laskowski, K., Singh, A. P., … Sethupathy, P. (2021). Multiomic analysis defines the first microRNA atlas across all small intestinal epithelial lineages and reveals novel markers of almost all major cell types. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 321(6), G668–G681. https://doi.org/10.1152/ajpgi.00222.2021

Cray, P., Sheahan, B. J., & Dekaney, C. M. (2021). [Review of Secretory Sorcery: Paneth Cell Control of Intestinal Repair and Homeostasis]. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 12(4), 1239–1250. https://doi.org/10.1016/j.jcmgh.2021.06.006

Cray, P., Sheahan, B. J., Cortes, J. E., & Dekaney, C. M. (2020). Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers. SCIENTIFIC REPORTS, 10(1). https://doi.org/10.1038/s41598-020-78473-1

Singh, A. P., Hung, Y.-H., Shanahan, M. T., Kanke, M., Bonfini, A., Dame, M. K., … Sethupathy, P. (2020). Enteroendocrine Progenitor Cell-Enriched mir-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent Manner. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 9(3), 447–464. https://doi.org/10.1016/j.jcmgh.2019.11.001

Jones, J. C., Brindley, C. D., Elder, N. H., Myers, M. G., Jr., Rajala, M. W., Dekaney, C. M., … Dempsey, P. J. (2019). Cellular Plasticity of Defa4(Cre)-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 7(3), 533–554. https://doi.org/10.1016/j.jcmgh.2018.11.004

Dekaney, C. M., King, S., Sheahan, B., & Cortes, J. E. (2019). Mist1 Expression Is Required for Paneth Cell Maturation. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 8(4), 549–560. https://doi.org/10.1016/j.jcmgh.2019.07.003

Sheahan, B., & Dekaney, C. M. (2018). Decrypting the Crypt: Novel Monoclonal Antibodies to Identify Intestinal Stem Cell Populations. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, Vol. 6, pp. 121–122. https://doi.org/10.1016/j.jcmgh.2018.04.006

Rigby, R. J., Carr, J., Orgel, K., King, S. L., Lund, P. K., & Dekaney, C. M. (2016). Intestinal bacteria are necessary for doxorubicin-induced intestinal damage but not for doxorubicin-induced apoptosis. Gut Microbes, 7(5), 414–423. https://doi.org/10.1080/19490976.2016.1215806

Carr, J., King, S. L., & Dekaney, C. M. (2015). 1009 Depletion of Enteric Microbiota Protects from Chemotherapy-Induced Damage in the Murine Small Intestine. Gastroenterology, 148(4), S-1132. https://doi.org/10.1016/S0016-5085(15)33862-2

King, S. L., Carr, J., & Dekaney, C. M. (2015). 798 Mist1 Is Necessary for Paneth Cell Maturation. Gastroenterology, 148(4), S-156-S-157. https://doi.org/10.1016/S0016-5085(15)30527-8

Seiler, K. M., Schenhals, E. L., von Furstenberg, R. J., Allena, B. K., Smith, B. J., Scaria, D., … Henning, S. J. (2015). Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage. Cell and Tissue Research, 361(2), 427–438. https://doi.org/10.1007/s00441-015-2111-1

Gewain, K., King, S. L., & Dekaney, C. M. (2013). Mo1824 Jejunal and Ileal Epithelium Demonstrate Differing Damage Responses to Doxorubicin Treatment. Gastroenterology, 144(5), S-672. https://doi.org/10.1016/S0016-5085(13)62492-0

King, S. L., Mohiuddin, J. J., & Dekaney, C. M. (2013). Paneth cells expand from newly created and preexisting cells during repair after doxorubicin-induced damage. American Journal of Physiology-Gastrointestinal and Liver Physiology, 305(2), G151–G162. https://doi.org/10.1152/ajpgi.00441.2012

King, S. L., & Dekaney, C. M. (2013). Small Intestinal Stem Cells. Current Opinion in Gastroenterology, 29, 140–145.

Packey, C. D., Gewain, K., Sartor, R. B., & Dekaney, C. M. (2013). Tu2027 The Chemotherapeutic Agent Doxorubicin Induces Contrasting Microbial Responses in the Jejunum and Distal Ileum That May Contribute to Differential Injury Patterns. Gastroenterology, 144(5), S-907-S-908. https://doi.org/10.1016/S0016-5085(13)63383-1

Dehmer, J. J., Garrison, A. P., Speck, K. E., Dekaney, C. M., Henning, S. J., & Helmrath, M. A. (2011). Characterization Of Intestinal Stem Cells During Development: The Role Of Lgr5. Journal of Surgical Research, 165(2), 339. https://doi.org/10.1016/j.jss.2010.11.142

Dehmer, J. J., Garrison, A. P., Speck, K. E., Dekaney, C. M., Van Landeghem, L., Sun, X., … Helmrath, M. A. (2011). Expansion of Intestinal Epithelial Stem Cells during Murine Development. PLoS ONE, 6(11), e27070. https://doi.org/10.1371/journal.pone.0027070

Rigby, R. J., Lund, P. K., & Dekaney, C. M. (2010). 750 Germ Free Mice Show Apoptosis but Dramatically Reduced Overt Mucosal Damage After Doxorubicin. Gastroenterology, 138(5), S-103. https://doi.org/10.1016/S0016-5085(10)60471-4

Dekaney, C. M. (2010). T1727 Paneth Cells Expand From a Pre-Existing Pool During Repair After Doxorubicin-Induced Damage. Gastroenterology, 138(5), S-566. https://doi.org/10.1016/S0016-5085(10)62605-4

Dekaney, C. M., Gulati, A. S., Helmrath, M. A., & Henning, S. J. (2009). 488 Regeneration of Intestinal Stem Cells Following Doxorubicin Treatment of Mice. Gastroenterology, 136(5), A-79. https://doi.org/10.1016/S0016-5085(09)60354-1

Garrison, A. P., Dekaney, C. M., von Allmen, D. C., Lund, P. K., Henning, S. J., & Helmrath, M. A. (2009). Early but not late administration of glucagon-like peptide-2 following ileo-cecal resection augments putative intestinal stem cell expansion. American Journal of Physiology-Gastrointestinal and Liver Physiology, 296(3), G643–G650. https://doi.org/10.1152/ajpgi.90588.2008

Dekaney, C. M., Gulati, A. S., Garrison, A. P., Helmrath, M. A., & Henning, S. J. (2009). Regeneration of intestinal stem/progenitor cells following doxorubicin treatment of mice. American Journal of Physiology-Gastrointestinal and Liver Physiology, 297(3), G461–G470. https://doi.org/10.1152/ajpgi.90446.2008

Garrison, A. P., Dekaney, C. M., von Allmen, D. C., Henning, S. J., & Helmrath, M. A. (2008). 163. Timing of Glucagon-Like Peptide-2 (GLP-2) Required for Augmented Expansion of Intestinal Stem Cells Following Ileo-Cecal Resection (ICR) in Mice. Journal of Surgical Research, 144(2), 249–250. https://doi.org/10.1016/j.jss.2007.12.186

Dekaney, C. M., von Allmen, D. C., Garrison, A. P., Rigby, R. J., Lund, P. K., Henning, S. J., & Helmrath, M. A. (2008). 29. Bacterial Dependent up Regulation of Ileal Bile Acid Binding Protein and Bile Acid Transporters Is FXR-Mediated Following Ileo-Cecal Resection (ICR). Journal of Surgical Research, 144(2), 188–189. https://doi.org/10.1016/j.jss.2007.12.034

Dekaney, C. M., von Allmen, D. C., Garrison, A. P., Rigby, R. J., Lund, P. K., Henning, S. J., & Helmrath, M. A. (2008). Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection. Surgery, 144(2), 174–181. https://doi.org/10.1016/j.surg.2008.03.035

Garrison, A. P., Dekaney, C. M., von Allmen, D. C., Henning, S. J., & Helmrath, M. A. (2008). Developmental insight into intestinal adaptation: characterization of intestinal stem cell (ISC) expansion and glucagon-like peptide-2 (GLP-2) actions during murine intestinal development. Journal of the American College of Surgeons, 207(3), S55–S56. https://doi.org/10.1016/j.jamcollsurg.2008.06.120

Dekaney, C. M., Wu, G., Yin, Y.-L., & Jaeger, L. A. (2008). Regulation of ornithine aminotransferase gene expression and activity by all-transretinoic acid in Caco-2 intestinal epithelial cells. The Journal of Nutritional Biochemistry, 19(10), 674–681. https://doi.org/10.1016/j.jnutbio.2007.09.002

Garrison, A. P., Dekaney, C. M., von Allmen, D. C., Lund, P. K., Henning, S. J., & Helmrath, M. A. (2008). T1818 Early Administration of Glucagon-Like Peptide-2 (GLP-2) Following Ileocecal Resection Augments Insulin-Like Growth Factor-I (IGF-I) Signaling During Intestinal Stem Cell Expansion. Gastroenterology, 134(4), A-569-A-570. https://doi.org/10.1016/S0016-5085(08)62659-1

Dekaney, C. M., Fong, J. J., Rigby, R. J., Lund, P. K., Henning, S. J., & Helmrath, M. A. (2007). Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice. American Journal of Physiology-Gastrointestinal and Liver Physiology, 293(5), G1013–G1022. https://doi.org/10.1152/ajpgi.00218.2007

Helmrath, M. A., Fong, J. J., Dekaney, C. M., & Henning, S. J. (2007). Rapid expansion of intestinal secretory lineages following a massive small bowel resection in mice. American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(1), G215–G222. https://doi.org/10.1152/ajpgi.00188.2006

Dekaney, C. M., Fong, J., Rodriguez, J. M., Henning, S. J., & Helmrath, M. A. (2006). Massive small bowel resection results in sustained increases in intestinal stem cell number. Journal of Surgical Research, 130(2), 253. https://doi.org/10.1016/j.jss.2005.11.262

Dekaney, C. M., Rodriguez, J. M., Graul, M. C., & Henning, S. J. (2006). Reply. Gastroenterology, 130(3), 1013–1014. https://doi.org/10.1053/J.GASTRO.2006.01.076

Dekaney, C. M., Rodriguez, J. M., Graul, M. C., & Henning, S. J. (2005). Isolation and Characterization of a Putative Intestinal Stem Cell Fraction From Mouse Jejunum. Gastroenterology, 129(5), 1567–1580. https://doi.org/10.1053/j.gastro.2005.08.011

Helmrath, M. A., Fong, J. J., Dekaney, C. M., & Henning, H. S. (2004). Early activation of Wnt β-catenin system following a massive small bowel resection in mice. Journal of Surgical Research, 121(2), 309–310. https://doi.org/10.1016/j.jss.2004.07.140